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mAbs Volume 3, 2011 - Issue 4
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Review

Immunoglobulin A

A next generation of therapeutic antibodies?

Jantine E. Bakema Department of Molecular Cell Biology and Immunology; VU University Medical Center; Amsterdam, The Netherlands
&
Marjolein van Egmond Department of Molecular Cell Biology and Immunology, Department of Surgery; VU University Medical Center; Amsterdam, The NetherlandsCorrespondence[email protected]
Pages 352-361 | Received 20 Jun 2011, Accepted 11 May 2011, Published online: 01 Jul 2011

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Celine A.N. Sewnath, Leonie M. Behrens & Marjolein van Egmond. (2022) Targeting myeloid cells with bispecific antibodies as novel immunotherapies of cancer. Expert Opinion on Biological Therapy 22:8, pages 983-995.
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Jiatong Chai, Zeyu Sun, Shunli Zhang, Qi Zhou & Jiancheng Xu. (2022) An indirect approach for reference intervals establishment of immunoglobulin A, G and M: the combination of laboratory database and statistics. Scandinavian Journal of Clinical and Laboratory Investigation 82:4, pages 311-322.
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Kouya Yamaki, Masato Terashi, Saori Yamamoto, Rei Fujiwara, Jun-ichi Inoue, Kishi Shimizu, Sakura Yanagita, Yuma Doi, Kei-ichiro Kimura, Kayo Kotani, Mai Sugihara & Yutaka Koyama. (2022) Immunoglobulin a suppresses B cell receptor-mediated activation of mouse B cells with differential inhibition of signaling molecules. Immunopharmacology and Immunotoxicology 44:1, pages 76-86.
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Melissa Maria Johanna van Gool & Marjolein van Egmond. (2020) IgA and FcαRI: Versatile Players in Homeostasis, Infection, and Autoimmunity. ImmunoTargets and Therapy 9, pages 351-372.
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Martina Dicker & Richard Strasser. (2015) Using glyco-engineering to produce therapeutic proteins. Expert Opinion on Biological Therapy 15:10, pages 1501-1516.
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Kouya Yamaki, Kenji Miyatake, Takayuki Nakashima, Ayumi Morioka, Midori Yamamoto, Yuki Ishibashi, Ayaka Ito, Ayu Kuranishi & Shin Yoshino. (2014) Intravenous IgA complexed with antigen reduces primary antibody response to the antigen and anaphylaxis upon antigen re-exposure by inhibiting Th1 and Th2 activation in mice. Immunopharmacology and Immunotoxicology 36:5, pages 316-328.
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Jenny M. Woof. (2012) Insights from Fc receptor biology: A route to improved antibody reagents. mAbs 4:3, pages 291-293.
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Fabian Bohländer. (2023) A new hope? Possibilities of therapeutic IgA antibodies in the treatment of inflammatory lung diseases. Frontiers in Immunology 14.
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Leonie M. Behrens, Timo K. van den Berg & Marjolein van Egmond. (2022) Targeting the CD47-SIRPα Innate Immune Checkpoint to Potentiate Antibody Therapy in Cancer by Neutrophils. Cancers 14:14, pages 3366.
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Anju Maharjan, Ravi Gautam, JiHun Jo, Manju Acharya, DaEun Lee, Pramod Bahadur K C, Jin Gim, Sojung Sin, Hyocher Kim, ChangYul Kim, SooYeon Lee, SooJin Lee, Yong Heo & HyoungAh Kim. (2022) Comparison of Overall Immunity Levels among Workers at Grape Orchard, Rose Greenhouse, and Open-Field Onion Farm. Safety and Health at Work 13:2, pages 248-254.
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Charlotte de Fays, François M. Carlier, Sophie Gohy & Charles Pilette. (2022) Secretory Immunoglobulin A Immunity in Chronic Obstructive Respiratory Diseases. Cells 11:8, pages 1324.
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Hitomi Sugino, Yu Sawada & Motonobu Nakamura. (2021) IgA Vasculitis: Etiology, Treatment, Biomarkers and Epigenetic Changes. International Journal of Molecular Sciences 22:14, pages 7538.
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Fabian Bohländer, Dennis Riehl, Sabrina Weißmüller, Marcus Gutscher, Jörg Schüttrumpf & Stefanie Faust. (2021) Immunomodulation: Immunoglobulin Preparations Suppress Hyperinflammation in a COVID-19 Model via FcγRIIA and FcαRI. Frontiers in Immunology 12.
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Samantha K Davis, Kevin J Selva, Stephen J Kent & Amy W Chung. (2020) Serum IgA Fc effector functions in infectious disease and cancer. Immunology & Cell Biology 98:4, pages 276-286.
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Stephanie N. Langel, Claire E. Otero, David R. Martinez & Sallie R. Permar. (2020) Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection. PLOS Pathogens 16:3, pages e1008303.
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Merav E. Shaul & Zvi G. Fridlender. (2019) Tumour-associated neutrophils in patients with cancer. Nature Reviews Clinical Oncology 16:10, pages 601-620.
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Annelot Breedveld & Marjolein van Egmond. (2019) IgA and FcαRI: Pathological Roles and Therapeutic Opportunities. Frontiers in Immunology 10.
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Merav E. Shaul & Zvi G. Fridlender. (2018) Cancer‐related circulating and tumor‐associated neutrophils – subtypes, sources and function. The FEBS Journal 285:23, pages 4316-4342.
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Eric D. Frontera, Rafa M. Khansa, Dana L. Schalk, Lauren E. Leakan, Tracey J. Guerin-Edbauer, Manohar Ratnam, David H. Gorski & Cecilia L. Speyer. (2018) IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells. Breast Cancer Research and Treatment 172:3, pages 551-560.
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Roy Jefferis. 2014. State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 1. Monoclonal Antibody Therapeutics: Structure, Function, and Regulatory Space. State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 1. Monoclonal Antibody Therapeutics: Structure, Function, and Regulatory Space 35 68 .
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