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Stéphane Hausmann, Johan Geiser, Oscar Vadas, Verena Ducret, Karl Perron & Martina Valentini. (2020) Auxiliary domains of the HrpB bacterial DExH-box helicase shape its RNA preferences. RNA Biology 17:5, pages 637-650.
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Gonzalo I. Mendoza-Ochoa, J. David Barrass, Isabella E. Maudlin & Jean D. Beggs. (2019) Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo. RNA Biology 16:12, pages 1775-1784.
Read now
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Eva Absmeier, Karine F. Santos & Markus C. Wahl. (2016) Functions and regulation of the Brr2 RNA helicase during splicing. Cell Cycle 15:24, pages 3362-3377.
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Rogerio Alves de Almeida & Raymond T O’Keefe. (2015) The NineTeen Complex (NTC) and NTC-associated proteins as targets for spliceosomal ATPase action during pre-mRNA splicing . RNA Biology 12:2, pages 109-114.
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Articles from other publishers (85)
Xing Hu, Yan Ju & Yue‐Kang Zhang. (2023) Ivermectin as a potential therapeutic strategy for glioma. Journal of Neuroscience Research 102:1.
Crossref
Crossref
Che-Sheng Chung, Hsu Lei Wai, Ching-Yang Kao & Soo-Chen Cheng. (2023) An ATP-independent role for Prp16 in promoting aberrant splicing. Nucleic Acids Research 51:20, pages 10815-10828.
Crossref
Crossref
Tim Benedict Garbers, Marieke Enders, Piotr Neumann & Ralf Ficner. (2023) Crystal structure of Prp16 in complex with ADP. Acta Crystallographica Section F Structural Biology Communications 79:8, pages 200-207.
Crossref
Crossref
Katherine E. Bohnsack, Soon Yi, Sarah Venus, Eckhard Jankowsky & Markus T. Bohnsack. (2023) Cellular functions of eukaryotic RNA helicases and their links to human diseases. Nature Reviews Molecular Cell Biology.
Crossref
Crossref
Corbin S. Black, Thomas A. Whelan, Erin L. Garside, Andrew M. MacMillan, Naomi M. Fast & Stephen D. Rader. (2023) Spliceosome assembly and regulation: insights from analysis of highly reduced spliceosomes. RNA 29:5, pages 531-550.
Crossref
Crossref
Xindi Li, Changhao Li, Jiaying Zhu, Songxiao Zhong, Hongliang Zhu & Xiuren Zhang. (2023) Functions and mechanisms of RNA helicases in plants. Journal of Experimental Botany 74:7, pages 2295-2310.
Crossref
Crossref
Santiago Movilla, Maite Roca, Vicent Moliner & Alessandra Magistrato. (2023) Molecular Basis of RNA-Driven ATP Hydrolysis in DExH-Box Helicases. Journal of the American Chemical Society 145:12, pages 6691-6701.
Crossref
Crossref
Stéphane Hausmann, Johan Geiser & Martina Valentini. (2022) Mechanism of inhibition of bacterial RNA helicases by diazo dyes and implications for antimicrobial drug development. Biochemical Pharmacology 204, pages 115194.
Crossref
Crossref
Jirayu Nuadthaisong, Tanaporn Phetruen, Chanakan Techawisutthinan & Sittinan Chanarat. (2022) Insights into the Mechanism of Pre-mRNA Splicing of Tiny Introns from the Genome of a Giant Ciliate Stentor coeruleus. International Journal of Molecular Sciences 23:18, pages 10973.
Crossref
Crossref
Nele Hug, Stuart Aitken, Dasa Longman, Michaela Raab, Hannah Armes, Abigail R. Mann, Ana Rio-Machin, Jude Fitzgibbon, Kevin Rouault-Pierre & Javier F. Cáceres. (2022) A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation. RNA 28:9, pages 1224-1238.
Crossref
Crossref
Sarah Venus & Eckhard Jankowsky. (2022) Measuring the impact of cofactors on RNA helicase activities. Methods 204, pages 376-385.
Crossref
Crossref
Anirban Chakraborty, Linda Krause & Dagmar Klostermeier. (2022) Determination of rate constants for conformational changes of RNA helicases by single-molecule FRET TIRF microscopy. Methods 204, pages 428-441.
Crossref
Crossref
Raquel Crespo, Shringar Rao & Tokameh Mahmoudi. (2022) HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Crossref
Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd & Markus C. Wahl. (2022) A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing. Nature Communications 13:1.
Crossref
Crossref
Rizwan Ullah, Jia Li, Puxian Fang, Shaobo Xiao & Liurong Fang. (2022) DEAD/H-box helicases:Anti-viral and pro-viral roles during infections. Virus Research 309, pages 198658.
Crossref
Crossref
Nadia Ruiz-Gutierrez, Martin Rieu, Jimmy Ouellet, Jean-François Allemand, Vincent Croquette & Hervé Le Hir. 2022. Helicase Enzymes Part B. Helicase Enzymes Part B
359
403
.
Vanessa Cristina Arfelli & Leticia Fröhlich Archangelo. 2022. Transcriptomics in Health and Disease. Transcriptomics in Health and Disease
51
71
.
Daniel Jutzi & Marc-David Ruepp. 2022. Alternative Splicing. Alternative Splicing
1
19
.
Chen Zhao, Yingwei Li, Chunping Qiu, Jingying Chen, Huan Wu, Qiuman Wang, Xinyue Ma, Kun Song & Beihua Kong. (2021) Splicing Factor DDX23, Transcriptionally Activated by E2F1, Promotes Ovarian Cancer Progression by Regulating FOXM1. Frontiers in Oncology 11.
Crossref
Crossref
Ching-Yang Kao, En-Cih Cao, Hsu Lei Wai & Soo-Chen Cheng. (2021) Evidence for complex dynamics during U2 snRNP selection of the intron branchpoint. Nucleic Acids Research 49:17, pages 9965-9977.
Crossref
Crossref
Sittinan Chanarat. (2021) UBL5/Hub1: An Atypical Ubiquitin-Like Protein with a Typical Role as a Stress-Responsive Regulator. International Journal of Molecular Sciences 22:17, pages 9384.
Crossref
Crossref
Zhenwei Zhang, Norbert Rigo, Olexandr Dybkov, Jean-Baptiste Fourmann, Cindy L. Will, Vinay Kumar, Henning Urlaub, Holger Stark & Reinhard Lührmann. (2021) Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature 596:7871, pages 296-300.
Crossref
Crossref
Pascal Donsbach & Dagmar Klostermeier. (2021) Regulation of RNA helicase activity: principles and examples. Biological Chemistry 402:5, pages 529-559.
Crossref
Crossref
Katherine E. Bohnsack, Ralf Ficner, Markus T. Bohnsack & Stefanie Jonas. (2021) Regulation of DEAH-box RNA helicases by G-patch proteins. Biological Chemistry 402:5, pages 561-579.
Crossref
Crossref
Lisa M. Strittmatter, Charlotte Capitanchik, Andrew J. Newman, Martina Hallegger, Christine M. Norman, Sebastian M. Fica, Chris Oubridge, Nicholas M. Luscombe, Jernej Ule & Kiyoshi Nagai. (2021) psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation. Nature Communications 12:1.
Crossref
Crossref
Francesca De Bortoli, Sara Espinosa & Rui Zhao. (2021) DEAH-Box RNA Helicases in Pre-mRNA Splicing. Trends in Biochemical Sciences 46:3, pages 225-238.
Crossref
Crossref
Ulrich Kück & Olga Schmitt. (2021) The Chloroplast Trans-Splicing RNA–Protein Supercomplex from the Green Alga Chlamydomonas reinhardtii. Cells 10:2, pages 290.
Crossref
Crossref
Katherine A. Wood, Megan A. Eadsforth, William G. Newman & Raymond T. O’Keefe. (2021) The Role of the U5 snRNP in Genetic Disorders and Cancer. Frontiers in Genetics 12.
Crossref
Crossref
Rui Bai, Ruixue Wan, Chuangye Yan, Qi Jia, Jianlin Lei & Yigong Shi. (2021) Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science 371:6525.
Crossref
Crossref
Inga Jarmoskaite, Pilar Tijerina & Rick Russell. (2021) ATP utilization by a DEAD-box protein during refolding of a misfolded group I intron ribozyme. Journal of Biological Chemistry 296, pages 100132.
Crossref
Crossref
Yosser Zina Abdelkrim, Josette Banroques & N. Kyle Tanner. 2021. RNA Remodeling Proteins. RNA Remodeling Proteins
35
52
.
Frances Taschuk, Iulia Tapescu, Ryan H. Moy & Sara Cherry. (2020) DDX56 Binds to Chikungunya Virus RNA To Control Infection. mBio 11:5.
Crossref
Crossref
Junqiao Jia, Oleg M Ganichkin, Marco Preußner, Eva Absmeier, Claudia Alings, Bernhard Loll, Florian Heyd & Markus C Wahl. (2020) A Snu114–GTP–Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Research 48:8, pages 4572-4584.
Crossref
Crossref
Robert E. Boer, Zachary R. Torrey & John S. SchneeklothJr.Jr.. (2020) Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems. ACS Chemical Biology 15:4, pages 808-818.
Crossref
Crossref
Michael K. Studer, Lazar Ivanović, Marco E. Weber, Sabrina Marti & Stefanie Jonas. (2020) Structural basis for DEAH-helicase activation by G-patch proteins. Proceedings of the National Academy of Sciences 117:13, pages 7159-7170.
Crossref
Crossref
Florian HamannAndreas SchmittFilippo FavrettoRomina HofelePiotr NeumannShengQi XiangHenning Urlaub, Markus Zweckstetter & Ralf Ficner. (2020) Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proceedings of the National Academy of Sciences 117:6, pages 2948-2956.
Crossref
Crossref
Sittinan Chanarat & Jisnuson Svasti. (2020) Stress-induced upregulation of the ubiquitin-relative Hub1 modulates pre-mRNA splicing and facilitates cadmium tolerance in Saccharomyces cerevisiae. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:2, pages 118565.
Crossref
Crossref
Takashi Ideue & Tokio Tani. (2020) Centromeric Non-Coding RNAs: Conservation and Diversity in Function. Non-Coding RNA 6:1, pages 4.
Crossref
Crossref
Claudia Tanja MierkeClaudia Tanja Mierke. 2020. Cellular Mechanics and Biophysics. Cellular Mechanics and Biophysics
509
593
.
Nan-Ying Wu & Soo-Chen Cheng. (2019) Functional analysis of Cwc24 ZF-domain in 5′ splice site selection. Nucleic Acids Research 47:19, pages 10327-10339.
Crossref
Crossref
Rebecca Toroney, Klaus H. Nielsen & Jonathan P. Staley. (2019) Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6. Genes & Development 33:21-22, pages 1555-1574.
Crossref
Crossref
Berthold Kastner, Cindy L. Will, Holger Stark & Reinhard Lührmann. (2019) Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes. Cold Spring Harbor Perspectives in Biology 11:11, pages a032417.
Crossref
Crossref
Catarina Felisberto-Rodrigues, Jemima C. Thomas, Craig McAndrew, Yann-Vaï Le Bihan, Rosemary BurkePaul Workman & Rob L. M. van Montfort. (2019) Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release. Biochemical Journal 476:18, pages 2521-2543.
Crossref
Crossref
Amlan Roychowdhury, Clément Joret, Gabrielle Bourgeois, Valérie Heurgué-Hamard, Denis L J Lafontaine & Marc Graille. (2019) The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis. Nucleic Acids Research 47:14, pages 7548-7563.
Crossref
Crossref
Kanako Nishimura, Yukiko Cho, Kazuaki Tokunaga, Mitsuyoshi Nakao, Tokio Tani & Takashi Ideue. (2019) DEAH box RNA helicase DHX38 associates with satellite I noncoding RNA involved in chromosome segregation. Genes to Cells 24:8, pages 585-590.
Crossref
Crossref
Florian Hamann, Marieke Enders & Ralf Ficner. (2019) Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Research 47:8, pages 4349-4362.
Crossref
Crossref
Zheng Xing, Wai Kit Ma & Elizabeth J. Tran. (2018) The DDX5/Dbp2 subfamily of DEAD‐box RNA helicases. WIREs RNA 10:2.
Crossref
Crossref
Sebastian M. Fica, Chris Oubridge, Max E. Wilkinson, Andrew J. Newman & Kiyoshi Nagai. (2019) A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science 363:6428, pages 710-714.
Crossref
Crossref
Andreas Schmitt, Florian Hamann, Piotr Neumann & Ralf Ficner. (2018) Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallographica Section D Structural Biology 74:7, pages 643-654.
Crossref
Crossref
Max E. WilkinsonPei-Chun LinClemens PlaschkaKiyoshi Nagai. (2018) Cryo-EM Studies of Pre-mRNA Splicing: From Sample Preparation to Model Visualization. Annual Review of Biophysics 47:1, pages 175-199.
Crossref
Crossref
Kentaro Nakaminami & Motoaki Seki. 2018. Survival Strategies in Extreme Cold and Desiccation. Survival Strategies in Extreme Cold and Desiccation
23
44
.
Lydia Herzel, Diana S. M. Ottoz, Tara Alpert & Karla M. Neugebauer. (2017) Splicing and transcription touch base: co-transcriptional spliceosome assembly and function. Nature Reviews Molecular Cell Biology 18:10, pages 637-650.
Crossref
Crossref
Qingliang Zheng, Jin Hou, Ye Zhou, Zhenyang Li & Xuetao Cao. (2017) The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus. Nature Immunology 18:10, pages 1094-1103.
Crossref
Crossref
Ralf Ficner, Achim Dickmanns & Piotr Neumann. (2017) Studying structure and function of spliceosomal helicases. Methods 125, pages 63-69.
Crossref
Crossref
Ramazan Karaduman, Sittinan Chanarat, Boris Pfander & Stefan Jentsch. (2017) Error-Prone Splicing Controlled by the Ubiquitin Relative Hub1. Molecular Cell 67:3, pages 423-432.e4.
Crossref
Crossref
Jean-Baptiste Fourmann, Marcel J. Tauchert, Ralf Ficner, Patrizia Fabrizio & Reinhard Lührmann. (2017) Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2. Nucleic Acids Research 45:7, pages 4068-4080.
Crossref
Crossref
Masatoshi Mutazono, Misato Morita, Chihiro Tsukahara, Madoka Chinen, Shiori Nishioka, Tatsuhiro Yumikake, Kohei Dohke, Misuzu Sakamoto, Takashi Ideue, Jun-ichi Nakayama, Kojiro Ishii & Tokio Tani. (2017) The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin. PLOS Genetics 13:2, pages e1006606.
Crossref
Crossref
A K Kesarwani, O Ramirez, A K Gupta, X Yang, T Murthy, A C Minella & M M Pillai. (2016) Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3′ splice sites within RNA secondary structures. Oncogene 36:8, pages 1123-1133.
Crossref
Crossref
Marcel J Tauchert, Jean-Baptiste Fourmann, Reinhard Lührmann & Ralf Ficner. (2017) Structural insights into the mechanism of the DEAH-box RNA helicase Prp43. eLife 6.
Crossref
Crossref
Dmitry E. Agafonov, Marieke van Santen, Berthold Kastner, Prakash Dube, Cindy L. Will, Henning Urlaub & Reinhard Lührmann. (2016) ATPγS stalls splicing after B complex formation but prior to spliceosome activation. RNA 22:9, pages 1329-1337.
Crossref
Crossref
Chengfu Sun, Norbert Rigo, Patrizia Fabrizio, Berthold Kastner & Reinhard Lührmann. (2016) A protein map of the yeast activated spliceosome as obtained by electron microscopy. RNA 22:9, pages 1427-1440.
Crossref
Crossref
Chuangye YanRuixue WanRui BaiGaoxingyu HuangYigong Shi. (2016) Structure of a yeast activated spliceosome at 3.5 Å resolution. Science 353:6302, pages 904-911.
Crossref
Crossref
Carsten Boesler, Norbert Rigo, Maria M. Anokhina, Marcel J. Tauchert, Dmitry E. Agafonov, Berthold Kastner, Henning Urlaub, Ralf Ficner, Cindy L. Will & Reinhard Lührmann. (2016) A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. Nature Communications 7:1.
Crossref
Crossref
Cyril F. Bourgeois, Franck Mortreux & Didier Auboeuf. (2016) The multiple functions of RNA helicases as drivers and regulators of gene expression. Nature Reviews Molecular Cell Biology 17:7, pages 426-438.
Crossref
Crossref
Marcel J. Tauchert & Ralf Ficner. (2016)
Structural analysis of the spliceosomal RNA helicase Prp28 from the thermophilic eukaryote
Chaetomium thermophilum
. Acta Crystallographica Section F Structural Biology Communications 72:5, pages 409-416.
Crossref
Crossref
Paul A. Howles, Leigh K. Gebbie, David A. Collings, Arvind Varsani, Ronan C. Broad, Stephen Ohms, Rosemary J. Birch, Ann H. Cork, Tony Arioli & Richard E. Williamson. (2016) A temperature-sensitive allele of a putative mRNA splicing helicase down-regulates many cell wall genes and causes radial swelling in Arabidopsis thaliana. Plant Molecular Biology 91:1-2, pages 1-13.
Crossref
Crossref
Jean-Baptiste Fourmann, Olexandr Dybkov, Dmitry E Agafonov, Marcel J Tauchert, Henning Urlaub, Ralf Ficner, Patrizia Fabrizio & Reinhard Lührmann. (2016) The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction. eLife 5.
Crossref
Crossref
Inessa De, Jana Schmitzová & Vladimir Pena. (2016)
The organization and contribution of helicases to
RNA
splicing
. WIREs RNA 7:2, pages 259-274.
Crossref
Crossref
Athea Vichas, Matthew T. Laurie & Jennifer A. Zallen. (2015) The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity. Journal of Cell Biology 211:5, pages 1011-1024.
Crossref
Crossref
J. Rajan Prabu, Marisa Müller, Andreas W. Thomae, Steffen Schüssler, Fabien Bonneau, Peter B. Becker & Elena Conti. (2015) Structure of the RNA Helicase MLE Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling. Molecular Cell 60:3, pages 487-499.
Crossref
Crossref
Katja Meyer, Tino Koester & Dorothee Staiger. (2015) Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process. Biomolecules 5:3, pages 1717-1740.
Crossref
Crossref
Francesca Fiorini, Debjani Bagchi, Hervé Le Hir & Vincent Croquette. (2015) Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities. Nature Communications 6:1.
Crossref
Crossref
Kathleen C. Lehmann, Eric J. Snijder, Clara C. Posthuma & Alexander E. Gorbalenya. (2015) What we know but do not understand about nidovirus helicases. Virus Research 202, pages 12-32.
Crossref
Crossref
Ana Leitão, Marina Costa & Francisco Enguita. (2015) Unzippers, Resolvers and Sensors: A Structural and Functional Biochemistry Tale of RNA Helicases. International Journal of Molecular Sciences 16:2, pages 2269-2293.
Crossref
Crossref
Julien Robert-Paganin, Stéphane Réty & Nicolas Leulliot. (2015) Regulation of DEAH/RHA Helicases by G-Patch Proteins. BioMed Research International 2015, pages 1-9.
Crossref
Crossref
Zbigniew Warkocki, Cornelius Schneider, Sina Mozaffari-Jovin, Jana Schmitzová, Claudia Höbartner, Patrizia Fabrizio & Reinhard Lührmann. (2015) The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes & Development 29:1, pages 94-107.
Crossref
Crossref
W. Luke Ward & Rick Russell. 2015. RNA Remodeling Proteins. RNA Remodeling Proteins
1
16
.
Olivier Cordin, Daniela Hahn, Ross Alexander, Amit Gautam, Cosmin Saveanu, J. David Barrass & Jean D. Beggs. (2014) Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase. Nucleic Acids Research 42:22, pages 13897-13910.
Crossref
Crossref
Inga JarmoskaiteRick Russell. (2014) RNA Helicase Proteins as Chaperones and Remodelers. Annual Review of Biochemistry 83:1, pages 697-725.
Crossref
Crossref
Sina Möhlmann, Rebecca Mathew, Piotr Neumann, Andreas Schmitt, Reinhard Lührmann & Ralf Ficner. (2014) Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallographica Section D Biological Crystallography 70:6, pages 1622-1630.
Crossref
Crossref
Keerthi T. Chathoth, J. David Barrass, Shaun Webb & Jean D. Beggs. (2014) A Splicing-Dependent Transcriptional Checkpoint Associated with Prespliceosome Formation. Molecular Cell 53:5, pages 779-790.
Crossref
Crossref
Aydan Salman-Dilgimen, Pierre-Olivier Hardy, Justin D. Radolf, Melissa J. Caimano & George Chaconas. (2013) HrpA, an RNA Helicase Involved in RNA Processing, Is Required for Mouse Infectivity and Tick Transmission of the Lyme Disease Spirochete. PLoS Pathogens 9:12, pages e1003841.
Crossref
Crossref
Jeffrey Noland, Jonathan Breitenbach, Holly Popham, Sue Hum-Musser, Heiko Vogel & Richard Musser. (2013) Gut Transcription in Helicoverpa zea is Dynamically Altered in Response to Baculovirus Infection. Insects 4:3, pages 506-520.
Crossref
Crossref
Manhong Guo & Yuliang Wu. (2013) Fighting an old war with a new weapon-silencing transposons by Piwi-interacting RNA. IUBMB Life 65:9, pages 739-747.
Crossref
Crossref
Chyi-Ying A. Chen & Ann-Bin Shyu. (2013) Protein segregase meddles in remodeling of mRNA–protein complexes. Genes & Development 27:9, pages 980-984.
Crossref
Crossref