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Small GTPases Volume 2, 2011 - Issue 5
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Ca2+-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells

André Limnander Department of Medicine; Howard Hughes Medical Institute; Rosalind Russell Medical Research Center for Arthritis; University of California at San Francisco; San Francisco, CA USA
&
Arthur Weiss Department of Medicine; Howard Hughes Medical Institute; Rosalind Russell Medical Research Center for Arthritis; University of California at San Francisco; San Francisco, CA USACorrespondence[email protected]
Pages 282-288 | Received 11 Jul 2011, Accepted 18 Aug 2011, Published online: 01 Sep 2011

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Andre Limnander, Julie Zikherman, Tannia Lau, Michael Leitges, Arthur Weiss & Jeroen P. Roose. (2014) Protein Kinase Cδ Promotes Transitional B Cell-Negative Selection and Limits Proximal B Cell Receptor Signaling To Enforce Tolerance. Molecular and Cellular Biology 34:8, pages 1474-1485.
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Jenna M. DeLuca, Maegan K. Murphy, Xin Wang & Timothy J. Wilson. (2021) FCRL1 Regulates B Cell Receptor–Induced ERK Activation through GRB2. The Journal of Immunology 207:11, pages 2688-2698.
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Gwo‐Ching Sun, Chung‐Ren Jan & Wei‐Zhe Liang. (2019) Exploring the impact of a naturally occurring sapogenin diosgenin on underlying mechanisms of Ca 2+ movement and cytotoxicity in human prostate cancer cells . Environmental Toxicology 35:3, pages 395-403.
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Gwo‐Ching Sun, Wei‐Zhe Liang & Chung‐Ren Jan. (2019) Mechanisms underlying the effect of an oral antihyperglycaemic agent glyburide on calcium ion (Ca 2+ ) movement and its related cytotoxicity in prostate cancer cells . Clinical and Experimental Pharmacology and Physiology 47:1, pages 111-118.
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Franz Fenninger & Wilfred A. Jefferies. (2019) What’s Bred in the Bone: Calcium Channels in Lymphocytes. The Journal of Immunology 202:4, pages 1021-1030.
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Xinchen Li, Ying Ding, Mengting Zi, Li Sun, Wenjie Zhang, Shun Chen & Yuekang Xu. (2017) CD19, from bench to bedside. Immunology Letters 183, pages 86-95.
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Elias Hobeika, Peter J. Nielsen & David Medgyesi. (2015) Signaling mechanisms regulating B-lymphocyte activation and tolerance. Journal of Molecular Medicine 93:2, pages 143-158.
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Solrun M. Maggadottir & Kathleen E. Sullivan. (2014) The intersection of immune deficiency and autoimmunity. Current Opinion in Rheumatology 26:5, pages 570-578.
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Lenka S. Teodorovic, Chiara Babolin, Sarah L. Rowland, Sarah A. Greaves, David P. Baldwin, Raul M. Torres & Roberta Pelanda. (2014) Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodies. Proceedings of the National Academy of Sciences 111:27.
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Maike Buchner & Markus Müschen. (2014) Targeting the B-cell receptor signaling pathway in B lymphoid malignancies. Current Opinion in Hematology 21:4, pages 341-349.
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Randall F. Gill, Michael J. McCabe & Allen J. Rosenspire. (2014) Elements of the B Cell Signalosome Are Differentially Affected by Mercury Intoxication. Autoimmune Diseases 2014, pages 1-10.
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João Bosco Oliveira. 2014. Stiehm's Immune Deficiencies. Stiehm's Immune Deficiencies 461 474 .
Joao Bosco Oliveira, V. Koneti Rao, Helen Su & Michael Lenardo. 2014. The Autoimmune Diseases. The Autoimmune Diseases 695 709 .
João Bosco Oliveira. (2013) The expanding spectrum of the autoimmune lymphoproliferative syndromes. Current Opinion in Pediatrics 25:6, pages 722-729.
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Olga Ksionda, Andre Limnander & Jeroen P. Roose. (2013) RasGRP Ras guanine nucleotide exchange factors in cancer. Frontiers in Biology 8:5, pages 508-532.
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Hye Sun KuehnJulie E. NiemelaAndreia Rangel-SantosMingchang ZhangStefania Pittaluga, Jennifer L. StoddardAshleigh A. HusseyMoses O. Evbuomwan, Debra A. Long Priel, Douglas B. Kuhns, C. Lucy Park, Thomas A. FleisherGulbu UzelJoão B. Oliveira. (2013) Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans. Blood 121:16, pages 3117-3125.
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Thomas A. Fleisher & Joao Bosco Oliveira. (2012) Monogenic defects in lymphocyte apoptosis. Current Opinion in Allergy & Clinical Immunology 12:6, pages 609-615.
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