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Articles

Comparison of physicochemical properties and aqueous solubility of xanthone prepared via oil-in-water emulsion and complex coacervation techniques

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Pages 784-798 | Received 14 Jul 2017, Accepted 23 Feb 2018, Published online: 07 May 2018

Figures & data

Table 1. Physicochemical characteristics of pure xanthone, spray-dried O/W emulsion and oven-dried coacervates (Mean ± S.D, n = 9).

Figure 1. (a). Particle size distribution profile of spray-dried xanthone O/W emulsion. (b). Particle size distribution profile of oven-dried xanthone coacervates.

Figure 1. (a). Particle size distribution profile of spray-dried xanthone O/W emulsion. (b). Particle size distribution profile of oven-dried xanthone coacervates.

Figure 2. Photomicrographs at 100 x magnification of A: dispersed pure xanthone; B: dispersed oven-dried blank coacervate; C: dispersed oven-dried coacervates; D: dispersed spray-dried O/W emulsion.

Figure 2. Photomicrographs at 100 x magnification of A: dispersed pure xanthone; B: dispersed oven-dried blank coacervate; C: dispersed oven-dried coacervates; D: dispersed spray-dried O/W emulsion.

Figure 3. FESEM photographs of xanthone in A: spray-dried O/W emulsion; B: oven-dried coacervates.

Figure 3. FESEM photographs of xanthone in A: spray-dried O/W emulsion; B: oven-dried coacervates.

Figure 4. (a). FTIR spectrum of spray-dried blank emulsion, sample (xanthone in O/W emulsion) and pure xanthone. (b). FTIR spectrum of blank coacervate, sample (oven-dried xanthone coacervates) and pure xanthone.

Figure 4. (a). FTIR spectrum of spray-dried blank emulsion, sample (xanthone in O/W emulsion) and pure xanthone. (b). FTIR spectrum of blank coacervate, sample (oven-dried xanthone coacervates) and pure xanthone.

Figure 5. X-ray diffractograms of spray-dried xanthone in O/W emulsion, oven-dried xanthone coacervates and pure xanthone.

Figure 5. X-ray diffractograms of spray-dried xanthone in O/W emulsion, oven-dried xanthone coacervates and pure xanthone.

Figure 6. HPLC chromatograms at 237 nm of A: pure xanthone; B: spray-dried xanthone in O/W emulsion; C: oven-dried xanthone coacervates.

Figure 6. HPLC chromatograms at 237 nm of A: pure xanthone; B: spray-dried xanthone in O/W emulsion; C: oven-dried xanthone coacervates.

Figure 7. (a). DSC thermograms of spray-dried xanthone O/W emulsion, spray-dried blank O/W emulsion and pure xanthone under open pan condition. (b). DSC thermograms of spray-dried xanthone O/W emulsion under closed pan condition.

Figure 7. (a). DSC thermograms of spray-dried xanthone O/W emulsion, spray-dried blank O/W emulsion and pure xanthone under open pan condition. (b). DSC thermograms of spray-dried xanthone O/W emulsion under closed pan condition.

Figure 8. DSC thermograms of oven-dried xanthone coacervates, oven-dried blank coacervates and pure xanthone under open pan condition.

Figure 8. DSC thermograms of oven-dried xanthone coacervates, oven-dried blank coacervates and pure xanthone under open pan condition.