Nutraceutical, functional, and therapeutic properties of Garcinia cambogia: a review

Figures & data

Figure 1. Garcinia cambogia.

Table 1. Functional and nutraceutical properties of common phytochemicals in Cambogia.

Compound	Part of plant	Activity	References
Garbogiol	Roots	Inhibition of α-glucosid	Nguyen et al., 2019^[Citation17]
]Oxy-guttiferone i	Fruits	Hepatoprotective	Espirito et al., 2020^[Citation8]
Rheedia xanthone A	Peel	Anticancer activity	Kurniawan et al., 2021^[Citation23]
Oxy-guttiferone k2	Fruits	Antitumor activity	Wu et al., 2017^[Citation24]
Oxy-guttiferone k	Fruits	Anticancer and antitumor	Wu, M et al., 2015^[Citation25]
Oxy-guttiferone m	Fruits	Antiproliferative activity	Semwal et al., 2015^[Citation6]
garcinol	Peel	Anticancer, antiparasitic, Antiinflammatory, action on nervous system	Schobert et al., 2019^[Citation18]
Isogarcinol	Peel	Anticancer, action on nervous system, antiparasitic,	Schobert et al., 2019^[Citation18]
Guttiferone i	Fruits	Hepatoprotective	Jamila et al., 2017^[Citation19]
Guttiferone m	Fruits	Topoisomerase II inhibitor	Di micco et al., 2019^[Citation26]
Guttiferone k		Topoisomerase II inhibitor	Di micco et al., 2019^[Citation26]
Guttiferone j	Fruits	Semisynthesis and antimicrobial activity	Conceição et al., 2022^[Citation20]
Guttiferone n	Fruits	Antiplasmodial, antioxidant	Espirito et al., 2020^[Citation8]
Tartaric acid	Fruits	Antiemetic, expectorant	Sambavathas et al., 2022^[Citation21]
Heterocyclic amines	Fruits	Antiobesity	Murthy et al., 2019^[Citation27]
Citric acid	Fruits	Skin diseases, metabolic acidosis, renal infection	Nguyen et al., 2019^[Citation17]
Malic acid	Fruits	Antimicrobial	Abdallah et al., 2017^[Citation7]
Garcinialactone	Fruits	Nephroprotective, cardioprotective	Espirito Santo et al., 2020^[Citation8]
Amino acids	All parts	Amino acids are Arginine, asparagine, glutamine, threonin, glycine, proline, leucine, isoleucine, ornithine, and lysine. Amino acids are the most common amino acids	Espirito Santo et al., 2020^[Citation8]

Figure 2. Garcinia cambogia oil is highly beneficial for weight loss.

Figure 3. Multiple factors that contribute to the effect of HCA for Garcinia/anti-obesity: (a) Summary of regulation of the serotonin and the removal of food intakes; (b) Summary of reduction in de novo lipogenesis; (c) Summary of fat oxidation stimulation; and (d) Glucose reduction Summary; (a) and (b) contribute to Garcinia/HCA weight management effect, while (b) and [c) are responsible for the Garcinia/HCA anti-obesity effect.

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Data availability statement

Additional data will be made available on request