http://orcid.org/0000-0002-4198-2077
Figures & data
Figure 1. PD-L1 expression on tumor cells and host cells jointly support tumor outgrowth. Left: in a typical immunogenic tumor, both tumor cells and intratumoral host cells express PD-L1, resulting in progressive tumor growth. Middle: experimental genetic deletion of PD-L1 on tumor cells or the host results in reduced tumor growth, mediated by CD8 T cells. Right: complete removal of PD-L1 expression by addition of blocking antibodies results in tumor eradication.
