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ORIGINAL RESEARCH

Hepatic Arterial Infusion Chemotherapy as a Timing Strategy for Conversion Surgery to Treat Hepatocellular Carcinoma: A Single-Center Real-World Study

, , , , , ORCID Icon, , , , ORCID Icon, ORCID Icon, , & show all
Pages 999-1010 | Received 28 Jun 2022, Accepted 09 Sep 2022, Published online: 14 Sep 2022

Figures & data

Table 1 Baseline Characteristics of Patients with Hepatocellular Carcinoma

Figure 1 Flow diagram of patients with hepatocellular carcinoma who underwent either hepatectomy or HAIC-hepatectomy.

Figure 1 Flow diagram of patients with hepatocellular carcinoma who underwent either hepatectomy or HAIC-hepatectomy.

Figure 2 A visualization of the Propensity Score Matching.

Figure 2 A visualization of the Propensity Score Matching.

Figure 3 Kaplan-Meier curves for RFS in the Surgery and HAIC-Surgery groups. Vertical bars indicate censoring of patients alive at their last follow-up.

Figure 3 Kaplan-Meier curves for RFS in the Surgery and HAIC-Surgery groups. Vertical bars indicate censoring of patients alive at their last follow-up.

Table 2 Study Surgery-Related Complications for Patients Who Underwent Either Hepatectomy or Hepatectomy After HAIC

Figure 4 Waterfall plots depicting the change of ALBI grade before and after hepatectomy (A and B); Comparison of ALBI score of patients after HAIC conversion therapy and before surgery. ALBI, albumin-bilirubin (C). Yellow triangle: ALBI score before HAIC; blue marks: ALBI score before surgery; red squares: ALBI score after surgery; grey lines: changes of ALBI score before HAIC and before surgery in the same patient; green lines: changes of ALBI score before and after surgery in the same patient.

Figure 4 Waterfall plots depicting the change of ALBI grade before and after hepatectomy (A and B); Comparison of ALBI score of patients after HAIC conversion therapy and before surgery. ALBI, albumin-bilirubin (C). Yellow triangle: ALBI score before HAIC; blue marks: ALBI score before surgery; red squares: ALBI score after surgery; grey lines: changes of ALBI score before HAIC and before surgery in the same patient; green lines: changes of ALBI score before and after surgery in the same patient.

Table 3 Correlation Analysis of Tumor Stage and Tumor Size with HAIC Cycles of Treatment

Table 4 Correlation Analysis of 4 Major Postoperative Complications with HAIC Cycles of Treatment