Journal of Hepatocellular Carcinoma, Volume 9, Issue (2022)

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Journal of Hepatocellular Carcinoma, Volume 9, Issue (2022)

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Original Research

Article
Factors Associated with Survival of Hepatocellular Carcinoma (HCC) Patients at a Safety Net Hospital in Arizona without On-Site Liver Transplant Program
Erica Turse, Majd Aboona, Ericka Charley, Arnold Forlemu, Tessa Bowie, Bikash Bhattarai, Keng-Yu Chuang & Abdul Nadir
Pages: 1-11
Published online: 22 Jan 2022
AbstractforFactors Associated with Survival of Hepatocellular Carcinoma (HCC) Patients at a Safety Net Hospital in Arizona without On-Site Liver Transplant Program | Full Text | References | PDF (840.6 KB) | EPUB
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Open Access
Article
Surgical Strategy for Resecting Hepatocellular Carcinoma in the Caudate Lobe: Isolated or Combined Lobectomy? A Single-Center Study and Meta-Analysis
Zheng-Gang Xu, Fei-Hong Zhang, Dong-Wei Sun, Qi-Tong Zheng, Gu-Wei Ji & Ke Wang
Pages: 13-25
Published online: 26 Jan 2022
AbstractforSurgical Strategy for Resecting Hepatocellular Carcinoma in the Caudate Lobe: Isolated or Combined Lobectomy? A Single-Center Study and Meta-Analysis | Full Text | References | PDF (6.6 MB) | EPUB
  • 123 Views
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Open Access

Retraction

Retraction
Drug-Eluting Bead Transarterial Chemoembolization versus Conventional Transarterial Chemoembolization Both Combined Apatinib for Hepatocellular Carcinoma: A Retrospective, Propensity-Score Matched Study [Retraction]
Pages: 27-28
Published online: 28 Jan 2022
CitationforDrug-Eluting Bead Transarterial Chemoembolization versus Conventional Transarterial Chemoembolization Both Combined Apatinib for Hepatocellular Carcinoma: A Retrospective, Propensity-Score Matched Study [Retraction] | Full Text | PDF (135.5 KB) | EPUB
  • 85 Views
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Open Access

Original Research

Article
Dynamic Lymphocyte Changes Following Transarterial Radioembolization: Association with Normal Liver Dose and Effect on Overall Survival
Shamar Young, Ranjan Ragulojan, Ting Chen, Joshua Owen, Donna D’souza, Tina Sanghvi, Jafar Golzarian & Siobhan Flanagan
Pages: 29-39
Published online: 04 Feb 2022
AbstractforDynamic Lymphocyte Changes Following Transarterial Radioembolization: Association with Normal Liver Dose and Effect on Overall Survival | Full Text | References | PDF (2.2 MB) | EPUB
  • 124 Views
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Open Access

Review

Review Article
Current Perspective of Traditional Chinese Medicines and Active Ingredients in the Therapy of Hepatocellular Carcinoma
Yuyao Li, Yue Li, Jinghao Zhang, Longshan Ji, Man Li, Xuehua Sun, Hai Feng, Zhuo Yu & Yueqiu Gao
Pages: 41-56
Published online: 09 Feb 2022
AbstractforCurrent Perspective of Traditional Chinese Medicines and Active Ingredients in the Therapy of Hepatocellular Carcinoma | Full Text | References | PDF (2.1 MB) | EPUB
  • 384 Views
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Open Access

Original Research

Article
CtBP1 Mediates Hypoxia-Induced Sarcomatoid Transformation in Hepatocellular Carcinoma
Xiaoling Zhang, Xiaoyu Wang, Liting Jia, Yang Yang, Fan Yang & Shengjun Xiao
Pages: 57-67
Published online: 11 Feb 2022
AbstractforCtBP1 Mediates Hypoxia-Induced Sarcomatoid Transformation in Hepatocellular Carcinoma | Full Text | References | PDF (9.8 MB) | EPUB
  • 112 Views
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Open Access
Article
Hepatocellular Carcinoma Risk Prediction in the NIH-AARP Diet and Health Study Cohort: A Machine Learning Approach
Jonathan Thomas, Linda M Liao, Rashmi Sinha, Tushar Patel & Samuel O Antwi
Pages: 69-81
Published online: 15 Feb 2022
AbstractforHepatocellular Carcinoma Risk Prediction in the NIH-AARP Diet and Health Study Cohort: A Machine Learning Approach | Full Text | References | PDF (3.3 MB) | EPUB
  • 117 Views
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Open Access
Article
SLC39A1 Overexpression is Associated with Immune Infiltration in Hepatocellular Carcinoma and Promotes Its Malignant Progression
Xiaowu Ma, Hongkai Zhuang, Qingbin Wang, Lei Yang, Zhiqin Xie, Ziyu Zhang, Wenliang Tan, Chenwei Tang, Yajin Chen & Changzhen Shang
Pages: 83-98
Published online: 15 Feb 2022
AbstractforSLC39A1 Overexpression is Associated with Immune Infiltration in Hepatocellular Carcinoma and Promotes Its Malignant Progression | Full Text | References | PDF (12 MB) | EPUB
  • 156 Views
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Open Access

Review

Review Article
Current Perspectives on the Unique Roles of Exosomes in Drug Resistance of Hepatocellular Carcinoma
Dongdong Xue, Jingzhao Han, Ze Liang, Lin Jia, Yifan Liu, Hongfang Tuo & Yanhui Peng
Pages: 99-112
Published online: 18 Feb 2022
AbstractforCurrent Perspectives on the Unique Roles of Exosomes in Drug Resistance of Hepatocellular Carcinoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 287 Views
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Open Access

Original Research

Article
MicroRNA-128-3p Mediates Lenvatinib Resistance of Hepatocellular Carcinoma Cells by Downregulating c-Met
Xin Xu, Wenjing Jiang, Peng Han, Jingyan Zhang, Liquan Tong & Xueying Sun
Pages: 113-126
Published online: 27 Feb 2022
AbstractforMicroRNA-128-3p Mediates Lenvatinib Resistance of Hepatocellular Carcinoma Cells by Downregulating c-Met | Full Text | References | PDF (11.9 MB) | EPUB
  • 182 Views
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Open Access
Article
Postoperative Adjuvant Transarterial Chemoembolization Plus Tyrosine Kinase Inhibitor for Hepatocellular Carcinoma: a Multicentre Retrospective Study
Kongying Lin, Fuqun Wei, Qizhen Huang, Zisen Lai, Jinyu Zhang, Qingjing Chen, Yabin Jiang, Jie Kong, Shichuan Tang, Jianhuai Lin, Yufeng Chen, Jinhong Chen & Yongyi Zeng
Pages: 127-140
Published online: 08 Mar 2022
AbstractforPostoperative Adjuvant Transarterial Chemoembolization Plus Tyrosine Kinase Inhibitor for Hepatocellular Carcinoma: a Multicentre Retrospective Study | Full Text | References | PDF (1.9 MB) | EPUB
  • 133 Views
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Open Access
Article
The Oncogenic and Diagnostic Potential of Stanniocalcin 2 in Hepatocellular Carcinoma
Zhixian Wu, Hongwei Cheng, Jie Liu, Shuaishuai Zhang, Minda Zhang, Fangzhou Liu, Yinghui Li, Qian Huang, Yi Jiang, Shaohua Chen, Lizhi Lv, Dongliang Li & Jin-Zhang Zeng
Pages: 141-155
Published online: 08 Mar 2022
AbstractforThe Oncogenic and Diagnostic Potential of Stanniocalcin 2 in Hepatocellular Carcinoma | Full Text | References | PDF (8.9 MB) | EPUB
  • 135 Views
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Open Access
Article
Regorafenib Combined with PD-1 Blockade Immunotherapy versus Regorafenib as Second-Line Treatment for Advanced Hepatocellular Carcinoma: A Multicenter Retrospective Study
Jingjun Huang, Yongjian Guo, Wensou Huang, Xiaotao Hong, Yi Quan, Liteng Lin, Jingwen Zhou, Licong Liang, Yaqin Zhang, Juan Zhou, Mingyue Cai & Kangshun Zhu
Pages: 157-170
Published online: 10 Mar 2022
AbstractforRegorafenib Combined with PD-1 Blockade Immunotherapy versus Regorafenib as Second-Line Treatment for Advanced Hepatocellular Carcinoma: A Multicenter Retrospective Study | Full Text | References | PDF (6.3 MB) | EPUB
  • 220 Views
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Open Access
Article
Borealin Promotes Tumor Growth and Metastasis by Activating the Wnt/β-Catenin Signaling Pathway in Hepatocellular Carcinoma
Baiyang Chen, Yang Gu, Hui Shen, Qiangsheng Liu, Hongbo Wang, Yabo Li, Xifan Liu, Yu Liu, Qinghao Du, Huapeng Sun & Xiaofeng Liao
Pages: 171-188
Published online: 11 Mar 2022
AbstractforBorealin Promotes Tumor Growth and Metastasis by Activating the Wnt/β-Catenin Signaling Pathway in Hepatocellular Carcinoma | Full Text | References | PDF (16.8 MB) | EPUB
  • 126 Views
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Open Access
Article
Preoperative Radiomics Analysis of Contrast-Enhanced CT for Microvascular Invasion and Prognosis Stratification in Hepatocellular Carcinoma
Tingfeng Xu, Liying Ren, Minjun Liao, Bigeng Zhao, Rongyu Wei, Zhipeng Zhou, Yong He, Hao Zhang, Dongbo Chen, Hongsong Chen & Weijia Liao
Pages: 189-201
Published online: 20 Mar 2022
AbstractforPreoperative Radiomics Analysis of Contrast-Enhanced CT for Microvascular Invasion and Prognosis Stratification in Hepatocellular Carcinoma | Full Text | References | PDF (5.5 MB) | EPUB
  • 184 Views
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Open Access
Article
LRP1B is a Potential Biomarker for Tumor Immunogenicity and Prognosis of HCC Patients Receiving ICI Treatment
Yang Cheng, Rui Tang, Xiangzhao Li, Biao Wang, Yanling Cheng, Shuzhe Xiao, Penghui Sun, Wenxuan Yu, Cheng Li, Xinsheng Lin & Yun Zhu
Pages: 203-220
Published online: 22 Mar 2022
AbstractforLRP1B is a Potential Biomarker for Tumor Immunogenicity and Prognosis of HCC Patients Receiving ICI Treatment | Full Text | References | PDF (12.5 MB) | EPUB
  • 183 Views
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Open Access
Article
Autoantibody Against Ferritin Light Chain is a Serum Biomarker for the Detection of Liver Cirrhosis but Not Liver Cancer
Pengfei Ren, Keyan Wang, Jie Ma, Xiaoqin Cao, Jiuzhou Zhao, Chengzhi Zhao, Yongjun Guo & Hua Ye
Pages: 221-232
Published online: 29 Mar 2022
AbstractforAutoantibody Against Ferritin Light Chain is a Serum Biomarker for the Detection of Liver Cirrhosis but Not Liver Cancer | Full Text | References | PDF (4.8 MB) | EPUB
  • 136 Views
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Open Access

Review

Review Article
Systemic Therapy for Hepatocellular Carcinoma: Current Updates and Outlook
Yinjie Fan, Hang Xue & Huachuan Zheng
Pages: 233-263
Published online: 30 Mar 2022
AbstractforSystemic Therapy for Hepatocellular Carcinoma: Current Updates and Outlook | Full Text | References | PDF (1.3 MB) | EPUB
  • 340 Views
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Open Access

Original Research

Article
Safety and Efficacy of Transarterial Chemoembolization and Immune Checkpoint Inhibition with Camrelizumab for Treatment of Unresectable Hepatocellular Carcinoma
Jin-Xing Zhang, Pei Chen, Sheng Liu, Qing-Quan Zu, Hai-Bin Shi & Chun-Gao Zhou
Pages: 265-272
Published online: 31 Mar 2022
AbstractforSafety and Efficacy of Transarterial Chemoembolization and Immune Checkpoint Inhibition with Camrelizumab for Treatment of Unresectable Hepatocellular Carcinoma | Full Text | References | PDF (2.7 MB) | EPUB
  • 180 Views
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Open Access
Article
Noninvasive Imaging Evaluation Based on Computed Tomography of the Efficacy of Initial Transarterial Chemoembolization to Predict Outcome in Patients with Hepatocellular Carcinoma
Yanmei Dai, Huijie Jiang, Shi-Ting Feng, Yuwei Xia, Jinping Li, Sheng Zhao, Dandan Wang, Xu Zeng, Yusi Chen, Yanjie Xin & Dongmin Liu
Pages: 273-288
Published online: 05 Apr 2022
AbstractforNoninvasive Imaging Evaluation Based on Computed Tomography of the Efficacy of Initial Transarterial Chemoembolization to Predict Outcome in Patients with Hepatocellular Carcinoma | Full Text | References | PDF (6.1 MB) | EPUB
  • 140 Views
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Open Access
Article
MCT4 Promotes Hepatocellular Carcinoma Progression by Upregulating TRAPPC5 Gene
Zheyu Niu, Faji Yang, Hongguang Li, Jianlu Wang, Qingqiang Ni, Chaoqun Ma, Huaqiang Zhu, Hong Chang, Xu Zhou, Jun Lu & Hengjun Gao
Pages: 289-300
Published online: 08 Apr 2022
AbstractforMCT4 Promotes Hepatocellular Carcinoma Progression by Upregulating TRAPPC5 Gene | Full Text | References | PDF (6.8 MB) | EPUB
  • 143 Views
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Open Access
Article
Impact of PNPLA3 p.I148M and Hepatic Steatosis on Long-Term Outcomes for Hepatocellular Carcinoma and HBsAg Seroclearance in Chronic Hepatitis B
Rei-Chi Hsueh, Wan-Jung Wu, Chih-Lin Lin, Chun-Jen Liu, Yi-Wen Huang, Jui-Ting Hu, Chih-Feng Wu, Feng-Yu Sung, Wen-Jie Liu & Ming-Whei Yu
Pages: 301-313
Published online: 11 Apr 2022
AbstractforImpact of PNPLA3 p.I148M and Hepatic Steatosis on Long-Term Outcomes for Hepatocellular Carcinoma and HBsAg Seroclearance in Chronic Hepatitis B | Full Text | References | PDF (3.3 MB) | EPUB
  • 187 Views
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Open Access
Article
Antiviral Treatments Eliminate the Adverse Impacts of High Baseline HBV Loads on the Survival of HBV-Related HCC Patients
Zili Hu, Xuqi Sun, Jie Mei, Zhiwen Hu, Ziliang Yang, Jingyu Hou, Yizhen Fu, Xiaohui Wang & Minshan Chen
Pages: 315-325
Published online: 19 Apr 2022
AbstractforAntiviral Treatments Eliminate the Adverse Impacts of High Baseline HBV Loads on the Survival of HBV-Related HCC Patients | Full Text | References | PDF (1.3 MB) | EPUB
  • 105 Views
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Open Access
Article
Protodioscin Induces Mitochondrial Apoptosis of Human Hepatocellular Carcinoma Cells Through Eliciting ER Stress-Mediated IP3R Targeting Mfn1/Bak Expression
Chen-Lin Yu, Hsiang-Lin Lee, Shun-Fa Yang, Shih-Wei Wang, Ching-Pin Lin, Yi-Hsien Hsieh & Hui-Ling Chiou
Pages: 327-341
Published online: 24 Apr 2022
AbstractforProtodioscin Induces Mitochondrial Apoptosis of Human Hepatocellular Carcinoma Cells Through Eliciting ER Stress-Mediated IP3R Targeting Mfn1/Bak Expression | Full Text | References | PDF (11.4 MB) | EPUB
  • 211 Views
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Open Access

Review

Review Article
An Overview of Hepatocellular Carcinoma After Insufficient Radiofrequency Ablation
Yusheng Guo, Yanqiao Ren, Xiangjun Dong, Xuefeng Kan & Chuansheng Zheng
Pages: 343-355
Published online: 26 Apr 2022
AbstractforAn Overview of Hepatocellular Carcinoma After Insufficient Radiofrequency Ablation | Full Text | References | PDF (547.7 KB) | EPUB
  • 190 Views
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Open Access

Original Research

Article
Skull Base Metastasis from Hepatocellular Carcinoma: Clinical Presentation and Efficacy of Radiotherapy
Kangpyo Kim, Joongyo Lee & Jinsil Seong
Pages: 357-366
Published online: 29 Apr 2022
AbstractforSkull Base Metastasis from Hepatocellular Carcinoma: Clinical Presentation and Efficacy of Radiotherapy | Full Text | References | PDF (2.5 MB) | EPUB
  • 160 Views
  • 1 CrossRef citations
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Open Access
Article
Nonsynonymous C1653T Mutation of Hepatitis B Virus X Gene Enhances Malignancy of Hepatocellular Carcinoma Cells
Cuifang Zhang, Ying Xie, Ruixue Lai, Jianhua Wu & Zhanjun Guo
Pages: 367-377
Published online: 03 May 2022
AbstractforNonsynonymous C1653T Mutation of Hepatitis B Virus X Gene Enhances Malignancy of Hepatocellular Carcinoma Cells | Full Text | References | PDF (5.5 MB) | EPUB
  • 159 Views
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Open Access

Review

Review Article
Macrotrabecular-Massive Hepatocellular Carcinoma: What Should We Know?
Xiaoming Li, Qiandong Yao, Chen Liu, Jian Wang, Huarong Zhang, Shiguang Li & Ping Cai
Pages: 379-387
Published online: 05 May 2022
AbstractforMacrotrabecular-Massive Hepatocellular Carcinoma: What Should We Know? | Full Text | References | PDF (1.7 MB) | EPUB
  • 217 Views
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Open Access

Original Research

Article
Identification and Validation of Novel Biomarkers for Hepatocellular Carcinoma, Liver Fibrosis/Cirrhosis and Chronic Hepatitis B via Transcriptome Sequencing Technology
Dandan Zhao, Xiaoxiao Zhang, Yuhui Tang, Peilin Guo, Rong Ai, Mengmeng Hou, Yiqi Wang, Xiwei Yuan, Luyao Cui, Yuguo Zhang, Suxian Zhao, Wencong Li, Yang Wang, Xiaoye Sun, Lingdi Liu, Shiming Dong, Lu Li, Wen Zhao & Yuemin Nan
Pages: 389-403
Published online: 09 May 2022
AbstractforIdentification and Validation of Novel Biomarkers for Hepatocellular Carcinoma, Liver Fibrosis/Cirrhosis and Chronic Hepatitis B via Transcriptome Sequencing Technology | Full Text | References | PDF (7 MB) | EPUB
  • 222 Views
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Open Access
Article
RNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial–Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma
Lu Zhang, Yi Zhang, Dongliang Shen, Ying Chen, Jianguo Feng, Xing Wang, Lunkun Ma, Yi Liao & Liling Tang
Pages: 405-422
Published online: 09 May 2022
AbstractforRNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial–Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma | Full Text | References | PDF (11.8 MB) | EPUB
  • 187 Views
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Open Access
Article
Platelet-Related Molecular Subtype to Predict Prognosis in Hepatocellular Carcinoma
Genhao Zhang
Pages: 423-436
Published online: 19 May 2022
AbstractforPlatelet-Related Molecular Subtype to Predict Prognosis in Hepatocellular Carcinoma | Full Text | References | PDF (11 MB) | EPUB
  • 138 Views
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Open Access
Article
Application of the CT/MRI LI-RADS Treatment Response Algorithm to Contrast-Enhanced Ultrasound: A Feasibility Study
Si-Min Ruan, Mei-Qing Cheng, Hui Huang, Hang-Tong Hu, Wei Li, Xiao-Yan Xie, Ming-De Lu, Ming Kuang, Man-Xia Lin & Wei Wang
Pages: 437-451
Published online: 20 May 2022
AbstractforApplication of the CT/MRI LI-RADS Treatment Response Algorithm to Contrast-Enhanced Ultrasound: A Feasibility Study | Full Text | References | PDF (5.1 MB) | EPUB
  • 132 Views
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Open Access
Article
CT-Based Radiomics for the Recurrence Prediction of Hepatocellular Carcinoma After Surgical Resection
Fang Wang, Qingqing Chen, Yuanyuan Zhang, Yinan Chen, Yajing Zhu, Wei Zhou, Xiao Liang, Yunjun Yang & Hongjie Hu
Pages: 453-465
Published online: 23 May 2022
AbstractforCT-Based Radiomics for the Recurrence Prediction of Hepatocellular Carcinoma After Surgical Resection | Full Text | References | PDF (1.2 MB) | EPUB
  • 213 Views
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Open Access
Article
The Prognostic Role of Circulating FPR Before Operation in Patients with BCLC A-C Hepatocellular Carcinoma: A Retrospective Cohort Study
Yanjun Shen, Yawen Xu, Jianying Wei & Wendong Li
Pages: 467-476
Published online: 31 May 2022
AbstractforThe Prognostic Role of Circulating FPR Before Operation in Patients with BCLC A-C Hepatocellular Carcinoma: A Retrospective Cohort Study | Full Text | References | PDF (2.7 MB) | EPUB
  • 104 Views
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Open Access

Review

Review Article
Hepatocellular Carcinoma Due to Nonalcoholic Fatty Liver Disease: Current Concepts and Future Challenges
Muhammad Imran Ahmad, Muhammad Umair Khan, Sudha Kodali, Akshay Shetty, S Michelle Bell & David Victor
Pages: 477-496
Published online: 01 Jun 2022
AbstractforHepatocellular Carcinoma Due to Nonalcoholic Fatty Liver Disease: Current Concepts and Future Challenges | Full Text | References | PDF (1.4 MB) | EPUB
  • 288 Views
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Open Access

Original Research

Article
Identification of KRBA1 as a Potential Prognostic Biomarker Associated with Immune Infiltration and m6A Modification in Hepatocellular Carcinoma
Yue Liu, Bidong Fu, Zichuan Yu, Gelin Song, Hong Zeng, Yiyang Gong, Yongqi Ding & Da Huang
Pages: 497-516
Published online: 31 May 2022
AbstractforIdentification of KRBA1 as a Potential Prognostic Biomarker Associated with Immune Infiltration and m6A Modification in Hepatocellular Carcinoma | Full Text | References | PDF (12.4 MB) | EPUB
  • 175 Views
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Open Access

Review

Review Article
Trial Designs for Integrating Novel Therapeutics into the Management of Intermediate-Stage Hepatocellular Carcinoma
Yung-Yeh Su, Yi-Sheng Liu, Chin-Fu Hsiao, Chiun Hsu & Li-Tzong Chen
Pages: 517-536
Published online: 02 Jun 2022
AbstractforTrial Designs for Integrating Novel Therapeutics into the Management of Intermediate-Stage Hepatocellular Carcinoma | Full Text | References | PDF (3.2 MB) | EPUB
  • 175 Views
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Open Access

Original Research

Article
Tumor Response and Nomogram-Based Prognostic Stratification for Hepatocellular Carcinoma After Drug-Eluting Beads Transarterial Chemoembolization
Kun Ji, Hanlong Zhu, Wei Wu, Xin Li, Pengchao Zhan, Yang Shi, Junhui Sun & Zhen Li
Pages: 537-551
Published online: 07 Jun 2022
AbstractforTumor Response and Nomogram-Based Prognostic Stratification for Hepatocellular Carcinoma After Drug-Eluting Beads Transarterial Chemoembolization | Full Text | References | PDF (2 MB) | EPUB
  • 127 Views
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Open Access
Article
CTB-193M12.5 Promotes Hepatocellular Carcinoma Progression via Enhancing NSD1-Mediated WNT10B/Wnt/β-Catenin Signaling Activation
Shuhua Zhang, Mi Jiang, Huan Cao, Jun Xiong & Jianqun Xu
Pages: 553-569
Published online: 07 Jun 2022
AbstractforCTB-193M12.5 Promotes Hepatocellular Carcinoma Progression via Enhancing NSD1-Mediated WNT10B/Wnt/β-Catenin Signaling Activation | Full Text | References | PDF (11.3 MB) | EPUB
  • 142 Views
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Open Access

Review

Review Article
Neoadjuvant Immunotherapy for Hepatocellular Carcinoma
Thomas U Marron, Myron Schwartz, Virginia Corbett & Miriam Merad
Pages: 571-581
Published online: 30 Jun 2022
AbstractforNeoadjuvant Immunotherapy for Hepatocellular Carcinoma | Full Text | References | PDF (397.3 KB) | EPUB
  • 255 Views
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Open Access
Review Article
Understanding the Role of Metabolic Syndrome as a Risk Factor for Hepatocellular Carcinoma
Norberto C Chavez-Tapia, Sofía Murúa-Beltrán Gall, Ana Luisa Ordoñez-Vázquez, Natalia Nuño-Lambarri, Paulina Vidal-Cevallos & Misael Uribe
Pages: 583-593
Published online: 05 Jul 2022
AbstractforUnderstanding the Role of Metabolic Syndrome as a Risk Factor for Hepatocellular Carcinoma | Full Text | References | PDF (1.3 MB) | EPUB
  • 202 Views
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Original Research

Article
Comparative Response of HCC Cells to TKIs: Modified in vitro Testing and Descriptive Expression Analysis
Paula Sagmeister, Jimmy Daza, Andrea Ofner, Andreas Ziesch, Liangtao Ye, Najib Ben Khaled, Matthias Ebert, Julia Mayerle, Andreas Teufel, Enrico N De Toni & Stefan Munker
Pages: 595-607
Published online: 09 Jul 2022
AbstractforComparative Response of HCC Cells to TKIs: Modified in vitro Testing and Descriptive Expression Analysis | Full Text | References | PDF (3.5 MB) | EPUB
  • 156 Views
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Open Access

REVIEW

Review
Systemic Therapy in Advanced Hepatocellular Carcinoma: Patient Selection and Key Considerations
Michael H Storandt, Amit Mahipal, Sri Harsha Tella, Anuhya Kommalapati & Zhaohui Jin
Pages: 1187-1200
Published online: 29 Nov 2022
AbstractforSystemic Therapy in Advanced Hepatocellular Carcinoma: Patient Selection and Key Considerations | Full Text | References | PDF (1 MB) | EPUB
  • 107 Views
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Open Access

ORIGINAL RESEARCH

Article
Integrated Analysis of Altered lncRNA, circRNA, microRNA, and mRNA Expression in Hepatocellular Carcinoma Carrying TERT Promoter Mutations
Haibin Zhang, Xiaolu Zhang & Jingya Yu
Pages: 1201-1215
Published online: 29 Nov 2022
AbstractforIntegrated Analysis of Altered lncRNA, circRNA, microRNA, and mRNA Expression in Hepatocellular Carcinoma Carrying TERT Promoter Mutations | Full Text | References | PDF (13.9 MB) | EPUB
  • 93 Views
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Open Access
Article
Transarterial Chemoembolization Combined with Immune Checkpoint Inhibitors Plus Tyrosine Kinase Inhibitors versus Immune Checkpoint Inhibitors Plus Tyrosine Kinase Inhibitors for Advanced Hepatocellular Carcinoma
Jin-Tao Huang, Bin-Yan Zhong, Nan Jiang, Wan-Ci Li, Shuai Zhang, Yu Yin, Jun Yang, Jian Shen, Wan-Sheng Wang & Xiao-Li Zhu
Pages: 1217-1228
Published online: 30 Nov 2022
AbstractforTransarterial Chemoembolization Combined with Immune Checkpoint Inhibitors Plus Tyrosine Kinase Inhibitors versus Immune Checkpoint Inhibitors Plus Tyrosine Kinase Inhibitors for Advanced Hepatocellular Carcinoma | Full Text | References | PDF (4.8 MB) | EPUB
  • 103 Views
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Open Access
Article
Vitamin B6 Metabolic Pathway is Involved in the Pathogenesis of Liver Diseases via Multi-Omics Analysis
Meihua Mei, Danping Liu, Xiuxin Tang, Ying You, Baogang Peng, Xiaoshun He & Junqi Huang
Pages: 729-750
Published online: 11 Aug 2022
AbstractforVitamin B6 Metabolic Pathway is Involved in the Pathogenesis of Liver Diseases via Multi-Omics Analysis | Full Text | References | PDF (14.3 MB) | EPUB
  • 210 Views
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Open Access
Article
Rethinking Liver Fibrosis Staging in Patients with Hepatocellular Carcinoma: New Insights from a Large Two-Center Cohort Study
Wei Xu, Bolun Li, Zhanwei Yang, Jingdong Li, Fei Liu & Yu Liu
Pages: 751-781
Published online: 12 Aug 2022
AbstractforRethinking Liver Fibrosis Staging in Patients with Hepatocellular Carcinoma: New Insights from a Large Two-Center Cohort Study | Full Text | References | PDF (22.3 MB) | EPUB
  • 74 Views
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Open Access
Article
Nomogram for the Preoperative Prediction of the Macrotrabecular-Massive Subtype of Hepatocellular Carcinoma
Yuying Shan, Xi Yu, Yong Yang, Jiannan Sun, Shengdong Wu, Shuqi Mao & Caide Lu
Pages: 717-728
Published online: 10 Aug 2022
AbstractforNomogram for the Preoperative Prediction of the Macrotrabecular-Massive Subtype of Hepatocellular Carcinoma | Full Text | References | PDF (4.2 MB) | EPUB
  • 81 Views
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Open Access
Article
Extending Surgical Resection for Hepatocellular Carcinoma Beyond Barcelona Clinic for Liver Cancer (BCLC) Stage A: A Novel Application of the Modified BCLC Staging System
Ian JY Wee, Fiona NN Moe, Rehena Sultana, Reiko WT Ang, Pearly PS Quek, Brian Kim Poh Goh, Chung Yip Chan, Peng Chung Cheow, Alexander YF Chung, Prema Raj Jeyaraj, Ye Xin Koh, Peter OP Mack, London Lucien PJ Ooi, Ek Khoon Tan, Jin Yao Teo, Juinn Huar Kam, Jacelyn SS Chua, Ashley WY Ng, Jade SQ Goh & Pierce KH Chow
Pages: 839-851
Published online: 17 Aug 2022
AbstractforExtending Surgical Resection for Hepatocellular Carcinoma Beyond Barcelona Clinic for Liver Cancer (BCLC) Stage A: A Novel Application of the Modified BCLC Staging System | Full Text | References | PDF (2.5 MB) | EPUB
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Article
Disruption of Growth Hormone Receptor Signaling Abrogates Hepatocellular Carcinoma Development
Abedul Haque, Vishal Sahu, Jamie Lynne Lombardo, Lianchun Xiao, Bhawana George, Robert A Wolff, Jeffrey S Morris, Asif Rashid, John J Kopchick, Ahmed O Kaseb & Hesham M Amin
Pages: 823-837
Published online: 15 Aug 2022
AbstractforDisruption of Growth Hormone Receptor Signaling Abrogates Hepatocellular Carcinoma Development | Full Text | References | PDF (8.3 MB) | EPUB
  • 123 Views
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Article
Safety and Efficacy of Drug-Eluting Beads Trans-Arterial Chemoembolization for Hepatocellular Carcinoma in Taiwan (SERENADE-T)
Yi-Sheng Liu, Pi-Yi Chang, Po-Chin Liang, Ming-Ching Ou, Jen-I Hwang & Chien-Hung Chen
Pages: 811-821
Published online: 15 Aug 2022
AbstractforSafety and Efficacy of Drug-Eluting Beads Trans-Arterial Chemoembolization for Hepatocellular Carcinoma in Taiwan (SERENADE-T) | Full Text | References | PDF (1 MB) | EPUB
  • 110 Views
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Article
Predictive Value of Preoperative Serum AFP, CEA, and CA19-9 Levels in Patients with Single Small Hepatocellular Carcinoma: Retrospective Study
Leijuan Gan, Shaohua Ren, Mengran Lang, Guangtao Li, Feng Fang, Lu Chen, Yayue Liu, Ruyu Han, Kangwei Zhu & Tianqiang Song
Pages: 799-810
Published online: 13 Aug 2022
AbstractforPredictive Value of Preoperative Serum AFP, CEA, and CA19-9 Levels in Patients with Single Small Hepatocellular Carcinoma: Retrospective Study | Full Text | References | PDF (673.1 KB) | EPUB
  • 141 Views
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Article
Effect of Transarterial Chemoembolization Plus Percutaneous Ethanol Injection or Radiofrequency Ablation for Liver Tumors
Lei Chen, Weihua Zhang, Tao Sun, Yanqiao Ren, Bo Sun, Licheng Zhu, Huangxuan Zhao & Chuansheng Zheng
Pages: 783-797
Published online: 12 Aug 2022
AbstractforEffect of Transarterial Chemoembolization Plus Percutaneous Ethanol Injection or Radiofrequency Ablation for Liver Tumors | Full Text | References | PDF (3.6 MB) | EPUB
  • 76 Views
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REVIEW

Review
Neoadjuvant Therapy for Hepatocellular Carcinoma
Zongyi Yin, Dongying Chen, Shuang Liang & Xiaowu Li
Pages: 929-946
Published online: 31 Aug 2022
AbstractforNeoadjuvant Therapy for Hepatocellular Carcinoma | Full Text | References | PDF (3.7 MB) | EPUB
  • 249 Views
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Review
Recurrent Hepatocellular Carcinoma: Patterns, Detection, Staging and Treatment
Dimitrios Papaconstantinou, Diamantis I Tsilimigras & Timothy M Pawlik
Pages: 947-957
Published online: 03 Sep 2022
AbstractforRecurrent Hepatocellular Carcinoma: Patterns, Detection, Staging and Treatment | Full Text | References | PDF (3.1 MB) | EPUB
  • 201 Views
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ORIGINAL RESEARCH

Article
The Prognostic Value of Baseline Clinical and Radiologic Imaging Features in Patients with Unresectable Hepatocellular Carcinoma Treated with Atezolizumab Plus Bevacizumab
Muhammad O Awiwi, Khaled M Elsayes, Yehia I Mohamed, Lina Altameemi, Migena Gjoni, Omayr Muhammad Irshad, Ahmed Sayed Ahmed, Ahmad O Kaseb & Usama Salem
Pages: 913-927
Published online: 30 Aug 2022
AbstractforThe Prognostic Value of Baseline Clinical and Radiologic Imaging Features in Patients with Unresectable Hepatocellular Carcinoma Treated with Atezolizumab Plus Bevacizumab | Full Text | References | PDF (581 KB) | EPUB
  • 96 Views
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Article
Lipid-Based Factors: A Promising New Biomarker for Predicting Prognosis and Conditional Survival Probability in Hepatocellular Carcinoma
Ziwei Guo & Jun Liang
Pages: 869-883
Published online: 26 Aug 2022
AbstractforLipid-Based Factors: A Promising New Biomarker for Predicting Prognosis and Conditional Survival Probability in Hepatocellular Carcinoma | Full Text | References | PDF (7.4 MB) | EPUB
  • 92 Views
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CORRIGENDUM

Correction
Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum]
Pages: 853-854
Published online: 29 Aug 2022
CitationforExperimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum] | Full Text | PDF (1.4 MB) | EPUB
  • 72 Views
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REVIEW

Review
Pathogenesis from Inflammation to Cancer in NASH-Derived HCC
Simiao Yu, Jingxiao Wang, Haocheng Zheng, Ruilin Wang, Nadia Johnson, Tao Li, Ping Li, Jie Lin, Yuan Li, Jin Yan, Ying Zhang, Zhenyu Zhu & Xia Ding
Pages: 855-867
Published online: 26 Aug 2022
AbstractforPathogenesis from Inflammation to Cancer in NASH-Derived HCC | Full Text | References | PDF (2.1 MB) | EPUB
  • 135 Views
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ORIGINAL RESEARCH

Article
Identification and Validation in a Novel Classification of Helicase Patterns for the Prediction of Tumor Proliferation and Prognosis
Yi Yin, Zi-Yuan Xu, Yuan-jie Liu, Wei Huang, Qian Zhang, Jie-pin Li & Xi Zou
Pages: 885-900
Published online: 27 Aug 2022
AbstractforIdentification and Validation in a Novel Classification of Helicase Patterns for the Prediction of Tumor Proliferation and Prognosis | Full Text | References | PDF (16 MB) | EPUB
  • 90 Views
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Article
A Novel Nomogram for Prediction of Post-Hepatectomy Liver Failure in Patients with Resectable Hepatocellular Carcinoma: A Multicenter Study
Jitao Wang, Zhanguo Zhang, Dong Shang, Yong Liao, Peng Yu, Jinling Li, Shubo Chen, Dengxiang Liu, Hongrui Miao, Shuang Li, Biao Zhang, Anliang Huang, Hao Liu, Yewei Zhang & Xiaolong Qi
Pages: 901-912
Published online: 27 Aug 2022
AbstractforA Novel Nomogram for Prediction of Post-Hepatectomy Liver Failure in Patients with Resectable Hepatocellular Carcinoma: A Multicenter Study | Full Text | References | PDF (5.1 MB) | EPUB
  • 87 Views
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Article
Circular RNA circRASSF5 Functions as an Anti-Oncogenic Factor in Hepatocellular Carcinoma by Acting as a Competitive Endogenous RNA Through Sponging miR-331-3p
Zhao Zhou, Xiaohan Cui, Peng Gao, Xudong Zhang, Chunfu Zhu & Beicheng Sun
Pages: 1041-1056
Published online: 04 Oct 2022
AbstractforCircular RNA circRASSF5 Functions as an Anti-Oncogenic Factor in Hepatocellular Carcinoma by Acting as a Competitive Endogenous RNA Through Sponging miR-331-3p | Full Text | References | PDF (11.8 MB) | EPUB
  • 77 Views
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REVIEW

Review
Assessment and Monitoring of Response to Systemic Treatment in Advanced Hepatocellular Carcinoma: Current Insights
Antonella Cammarota, Valentina Zanuso, Tiziana Pressiani, Nicola Personeni & Lorenza Rimassa
Pages: 1011-1027
Published online: 14 Sep 2022
AbstractforAssessment and Monitoring of Response to Systemic Treatment in Advanced Hepatocellular Carcinoma: Current Insights | Full Text | References | PDF (603.4 KB) | EPUB
  • 79 Views
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Review
Circulating Non-Coding RNAs as Potential Diagnostic Biomarkers in Hepatocellular Carcinoma
Tingsong Chen
Pages: 1029-1040
Published online: 15 Sep 2022
AbstractforCirculating Non-Coding RNAs as Potential Diagnostic Biomarkers in Hepatocellular Carcinoma | Full Text | References | PDF (597.8 KB) | EPUB
  • 84 Views
  • 3 CrossRef citations
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ORIGINAL RESEARCH

Article
Impaired Autophagy Response in Hepatocellular Carcinomas Enriches Glypican-3 in Exosomes, Not in the Microvesicles
Ali Riza Koksal, Paul Thevenot, Yucel Aydin, Kelley Nunez, Tyler Sandow, Kyle Widmer, Leela Nayak, John Scott, Molly Delk, Martin W Moehlen, Ari J Cohen & Srikanta Dash
Pages: 959-972
Published online: 07 Sep 2022
AbstractforImpaired Autophagy Response in Hepatocellular Carcinomas Enriches Glypican-3 in Exosomes, Not in the Microvesicles | Full Text | References | PDF (6.5 MB) | EPUB
  • 93 Views
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Article
Retrospective Study of the Efficacy and Safety of Chemoembolization with Drug-Eluting Microspheres Combined with Intra-Arterial Infusion of Bevacizumab for Unresectable Hepatocellular Carcinoma
Shota Ueda, Shinichi Hori, Atsushi Hori, Kazuhiro Makitani, Ke Wan & Tetsuo Sonomura
Pages: 973-985
Published online: 12 Sep 2022
AbstractforRetrospective Study of the Efficacy and Safety of Chemoembolization with Drug-Eluting Microspheres Combined with Intra-Arterial Infusion of Bevacizumab for Unresectable Hepatocellular Carcinoma | Full Text | References | PDF (2.2 MB) | EPUB
  • 114 Views
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Article
Efficacy and Safety of TKI Plus PD-1 Inhibitors in Elderly uHCC Patients: A Retrospective Study
Bowen Chen, Jin Lei, Haitao Zhao, Jinghui Dong, Zhen Zeng, Yinyin Li, Lingxiang Yu, Lin Zhou, Aiying Jia, Yinying Lu & Jiamin Cheng
Pages: 1171-1185
Published online: 08 Nov 2022
AbstractforEfficacy and Safety of TKI Plus PD-1 Inhibitors in Elderly uHCC Patients: A Retrospective Study | Full Text | References | PDF (772.2 KB) | EPUB
  • 79 Views
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Article
Incidence of Hepatocellular Carcinoma and Decompensated Liver Cirrhosis and Prognostic Accuracy of the PAGE-B HCC Risk Score in a Low Endemic Hepatitis B Virus Infected Population
Signe Bollerup, Frederik Engsig, Sofie Hallager, Amanda Mocroft, Birgit T Roege, Peer B Christensen, Alex L Laursen, Henrik Krarup, Mette R Clausen, Peter Thielsen, Lone G Madsen, Lars Noerregaard, Toke S Barfod, Ulla Balslev, Britta Tarp, Jesper B Hansen, Lone H Mygind, Jan Gerstoft & Nina Weis
Pages: 1093-1104
Published online: 18 Oct 2022
AbstractforIncidence of Hepatocellular Carcinoma and Decompensated Liver Cirrhosis and Prognostic Accuracy of the PAGE-B HCC Risk Score in a Low Endemic Hepatitis B Virus Infected Population | Full Text | References | PDF (2.7 MB) | EPUB
  • 62 Views
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CASE SERIES

Delayed Hepatocellular Carcinoma Recurrence After Liver Transplantation: Comprehensive Clinical Characterization of Case Series
Ta-Hsiang Wong, Cheng-Maw Ho, Hsao-Hsun Hsu, Yao-Ming Wu, Ming-Chih Ho, Po-Huang Lee & Rey-Heng Hu
Pages: 1081-1091
Published online: 17 Oct 2022
AbstractforDelayed Hepatocellular Carcinoma Recurrence After Liver Transplantation: Comprehensive Clinical Characterization of Case Series | Full Text | References | PDF (3.7 MB) | EPUB
  • 98 Views
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ORIGINAL RESEARCH

Article
Serum IGF-1 Scores and Clinical Outcomes in the Phase III IMbrave150 Study of Atezolizumab Plus Bevacizumab versus Sorafenib in Patients with Unresectable Hepatocellular Carcinoma
Ahmed O Kaseb, Yinghui Guan, Betul Gok Yavuz, Alexander R Abbas, Shan Lu, Elshad Hasanov, Han Chong Toh, Wendy Verret & Yulei Wang
Pages: 1065-1079
Published online: 11 Oct 2022
AbstractforSerum IGF-1 Scores and Clinical Outcomes in the Phase III IMbrave150 Study of Atezolizumab Plus Bevacizumab versus Sorafenib in Patients with Unresectable Hepatocellular Carcinoma | Full Text | References | PDF (992.6 KB) | EPUB
  • 93 Views
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Article
The Age, Gamma-Glutamyl Transpeptidase and Platelet Index: A Novel Noninvasive Model for Predicting Hepatocellular Carcinoma in Patients with Hepatitis B Virus-Related Liver Cirrhosis
Kai Liu, Zeyu Huang, Suhua Yang, Lin Lin, Shuqin Zheng, Xiujun Zhang, Yuan Xue & Weibin Xie
Pages: 1057-1063
Published online: 08 Oct 2022
AbstractforThe Age, Gamma-Glutamyl Transpeptidase and Platelet Index: A Novel Noninvasive Model for Predicting Hepatocellular Carcinoma in Patients with Hepatitis B Virus-Related Liver Cirrhosis | Full Text | References | PDF (1.7 MB) | EPUB
  • 65 Views
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CASE REPORT

Case Report
Thrombotic Thrombocytopenic Purpura After Radiofrequency Ablation of Hepatocellular Carcinoma: A Case Report
Renbiao Chen, Yonglei Zhao, Pierre Umba Mabombo, Hongjie Hu & Xiaoxuan Zhou
Pages: 1105-1108
Published online: 26 Oct 2022
AbstractforThrombotic Thrombocytopenic Purpura After Radiofrequency Ablation of Hepatocellular Carcinoma: A Case Report | Full Text | References | PDF (418.7 KB) | EPUB
  • 65 Views
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REVIEW

Review
Tumor Microenvironment in Hepatocellular Carcinoma: Key Players for Immunotherapy
Hai Feng, Yunhui Zhuo, Xuemei Zhang, Yuyao Li, Yue Li, Xiangjuan Duan, Jia Shi, Chengbin Xu, Yueqiu Gao & Zhuo Yu
Pages: 1109-1125
Published online: 26 Oct 2022
AbstractforTumor Microenvironment in Hepatocellular Carcinoma: Key Players for Immunotherapy | Full Text | References | PDF (3.5 MB) | EPUB
  • 141 Views
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ORIGINAL RESEARCH

Article
Neutrophil-to-Lymphocyte Ratio Can Distinguish Patients with Liver Cirrhosis from Healthy People but Cannot Distinguish Patients with Cirrhotic Hepatocellular Carcinoma from Patients with Liver Cirrhosis
Xuming Zhu & Hongxing Zhou
Pages: 1127-1136
Published online: 29 Oct 2022
AbstractforNeutrophil-to-Lymphocyte Ratio Can Distinguish Patients with Liver Cirrhosis from Healthy People but Cannot Distinguish Patients with Cirrhotic Hepatocellular Carcinoma from Patients with Liver Cirrhosis | Full Text | References | PDF (2.4 MB) | EPUB
  • 66 Views
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Article
Prognostic Value of Red Blood Cell Distribution Width (RDW) in the Recurrence of Hepatocellular Carcinoma Following Curative Resection
Mohammad Golriz, Ali Ramouz, Sadeq Ali-Hasan-Al-Saegh, Saeed Shafiei, Ehsan Aminizadeh, Ahmed Hammad, Markus Mieth, Christian Rupp, Christoph Springfeld, Katrin Hoffmann, Markus Büchler & Arianeb Mehrabi
Pages: 1137-1147
Published online: 31 Oct 2022
AbstractforPrognostic Value of Red Blood Cell Distribution Width (RDW) in the Recurrence of Hepatocellular Carcinoma Following Curative Resection | Full Text | References | PDF (3.2 MB) | EPUB
  • 88 Views
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REVIEW

Review
Understanding the Immunoenvironment of Primary Liver Cancer: A Histopathology Perspective
Annabelle Chung, David Nasralla & Alberto Quaglia
Pages: 1149-1169
Published online: 02 Nov 2022
AbstractforUnderstanding the Immunoenvironment of Primary Liver Cancer: A Histopathology Perspective | Full Text | References | PDF (3.5 MB) | EPUB
  • 115 Views
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ORIGINAL RESEARCH

Article
Effects of Early TACE Refractoriness on Survival in Patients with Hepatocellular Carcinoma: A Real-World Study
Chao Yang, Yin-gen Luo, Hong-cai Yang, Zhi-hang Yao & Xiao Li
Pages: 621-631
Published online: 21 Jul 2022
AbstractforEffects of Early TACE Refractoriness on Survival in Patients with Hepatocellular Carcinoma: A Real-World Study | Full Text | References | PDF (4.1 MB) | EPUB
  • 90 Views
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Article
Natural Killer Group 2D Receptor and B1a Cells Crosstalk in Post-Hepatitis C Virus Infection Hepatocellular Carcinoma and Cirrhosis
Reham Hammad, Mona A Eldosoky, Alshaimaa M Mosaad, Asmaa M El-Nasser, Fatma M Kotb, Salwa I Elshennawy, Noha Abdel-Rahman Eldesoky, Mohamed A Selim, Gina G Naguib, Ossama A Ahmed, Mohamed Alboraie & Reda Badr Aglan
Pages: 609-619
Published online: 18 Jul 2022
AbstractforNatural Killer Group 2D Receptor and B1a Cells Crosstalk in Post-Hepatitis C Virus Infection Hepatocellular Carcinoma and Cirrhosis | Full Text | References | PDF (3.9 MB) | EPUB
  • 78 Views
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Article
Preoperative Prognostic Nutritional Index May Be a Strong Predictor of Hepatocellular Carcinoma Recurrence Following Liver Transplantation
Arno Kornberg, Linda Kaschny, Jennifer Kornberg & Helmut Friess
Pages: 649-660
Published online: 27 Jul 2022
AbstractforPreoperative Prognostic Nutritional Index May Be a Strong Predictor of Hepatocellular Carcinoma Recurrence Following Liver Transplantation | Full Text | References | PDF (3.7 MB) | EPUB
  • 93 Views
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Article
Histological Severity of Cirrhosis Influences Surgical Outcomes of Hepatocellular Carcinoma After Curative Hepatectomy
Bin-Yong Liang, Jin Gu, Min Xiong, Er-Lei Zhang, Zun-Yi Zhang, Wan-Yee Lau, Shao-Fa Wang, Yan Guan, Xiao-Ping Chen & Zhi-Yong Huang
Pages: 633-647
Published online: 23 Jul 2022
AbstractforHistological Severity of Cirrhosis Influences Surgical Outcomes of Hepatocellular Carcinoma After Curative Hepatectomy | Full Text | References | PDF (8.5 MB) | EPUB
  • 80 Views
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REVIEW

Review
Macrotrabecular-Massive Hepatocellular Carcinoma: Light and Shadow in Current Knowledge
Anna Sessa, Sébastien Mulé, Raffaele Brustia, Hélène Regnault, Athena Galletto Pregliasco, Rami Rhaiem, Vincent Leroy, Daniele Sommacale, Alain Luciani, Julien Calderaro & Giuliana Amaddeo
Pages: 661-670
Published online: 27 Jul 2022
AbstractforMacrotrabecular-Massive Hepatocellular Carcinoma: Light and Shadow in Current Knowledge | Full Text | References | PDF (676.2 KB) | EPUB
  • 127 Views
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ORIGINAL RESEARCH

Article
Transarterial Chemoebolization in Hepatocellular Carcinoma: A Binational Japanese-German Study
Timo A Auer, Keitaro Sofue, Eisuke Ueshima, Nina Rauer, Takeru Yamaguchi, Bernhard Gebauer, Bernd Hamm, Takamichi Murakami & Christian E Althoff
Pages: 695-705
Published online: 01 Aug 2022
AbstractforTransarterial Chemoebolization in Hepatocellular Carcinoma: A Binational Japanese-German Study | Full Text | References | PDF (1.8 MB) | EPUB
  • 60 Views
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Article
Comparison of the Efficacy and Safety of Transarterial Chemoembolization with or without Lenvatinib for Unresectable Hepatocellular Carcinoma: A Retrospective Propensity Score–Matched Analysis
Yu-Xing Chen, Jin-Xing Zhang, Chun-Gao Zhou, Jin Liu, Sheng Liu, Hai-Bin Shi & Qing-Quan Zu
Pages: 685-694
Published online: 01 Aug 2022
AbstractforComparison of the Efficacy and Safety of Transarterial Chemoembolization with or without Lenvatinib for Unresectable Hepatocellular Carcinoma: A Retrospective Propensity Score–Matched Analysis | Full Text | References | PDF (2 MB) | EPUB
  • 62 Views
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Article
The Abnormal Proliferation of Hepatocytes is Associated with MC-LR and C-Terminal Truncated HBX Synergistic Disturbance of the Redox Balance
Dong-Mei Cai, Fan-Biao Mei, Chao-Jun Zhang, San-Chun An, Rui-Bo Lv, Guan-Hua Ren, Chan-Chan Xiao, Long Long, Tian-Ren Huang & Wei Deng
Pages: 1229-1246
Published online: 05 Dec 2022
AbstractforThe Abnormal Proliferation of Hepatocytes is Associated with MC-LR and C-Terminal Truncated HBX Synergistic Disturbance of the Redox Balance | Full Text | References | PDF (9.6 MB) | EPUB
  • 76 Views
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REVIEW

Review
Expert Insights on Current Treatments for Hepatocellular Carcinoma: Clinical and Molecular Approaches and Bottlenecks to Progress
Alexander H Shannon, Samantha M Ruff & Timothy M Pawlik
Pages: 1247-1261
Published online: 07 Dec 2022
AbstractforExpert Insights on Current Treatments for Hepatocellular Carcinoma: Clinical and Molecular Approaches and Bottlenecks to Progress | Full Text | References | PDF (3 MB) | EPUB
  • 141 Views
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ORIGINAL RESEARCH

Article
Hepatic Arterial Infusion Chemotherapy as a Timing Strategy for Conversion Surgery to Treat Hepatocellular Carcinoma: A Single-Center Real-World Study
Jiongliang Wang, Zhikai Zheng, Tianqing Wu, Wenxuan Li, Juncheng Wang, Yangxun Pan, Wei Peng, Dandan Hu, Jiajie Hou, Li Xu, Yaojun Zhang, Minshan Chen, Rongxin Zhang & Zhongguo Zhou
Pages: 999-1010
Published online: 14 Sep 2022
AbstractforHepatic Arterial Infusion Chemotherapy as a Timing Strategy for Conversion Surgery to Treat Hepatocellular Carcinoma: A Single-Center Real-World Study | Full Text | References | PDF (3.6 MB) | EPUB
  • 114 Views
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REVIEW

Review
Animal Models of Hepatocellular Carcinoma: Current Applications in Clinical Research
Francesca Fornari, Catia Giovannini, Fabio Piscaglia & Laura Gramantieri
Pages: 1263-1278
Published online: 08 Dec 2022
AbstractforAnimal Models of Hepatocellular Carcinoma: Current Applications in Clinical Research | Full Text | References | PDF (1.3 MB) | EPUB
  • 201 Views
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ORIGINAL RESEARCH

Article
Does HCC Etiology Impact the Efficacy of Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma? An Asian Liver Radiation Therapy Group Study
Nalee Kim, Jason Chia-Hsien Cheng, Nitin Ohri, Wen-Yen Huang, Tomoki Kimura, Zhao Chong Zeng, Victor Ho Fun Lee, Chul Seung Kay & Jinsil Seong
Pages: 707-715
Published online: 06 Aug 2022
AbstractforDoes HCC Etiology Impact the Efficacy of Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma? An Asian Liver Radiation Therapy Group Study | Full Text | References | PDF (2.9 MB) | EPUB
  • 99 Views
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Article
A Machine Learning Model Based on Health Records for Predicting Recurrence After Microwave Ablation of Hepatocellular Carcinoma
Chao An, Hongcai Yang, Xiaoling Yu, Zhi-Yu Han, Zhigang Cheng, Fangyi Liu, Jianping Dou, Bing Li, Yansheng Li, Yichao Li, Jie Yu & Ping Liang
Pages: 671-684
Published online: 28 Jul 2022
AbstractforA Machine Learning Model Based on Health Records for Predicting Recurrence After Microwave Ablation of Hepatocellular Carcinoma | Full Text | References | PDF (5.9 MB) | EPUB
  • 175 Views
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REVIEW

Review
Antitumor Effects and Mechanisms of Metabolic Syndrome Medications on Hepatocellular Carcinoma
Kyoko Oura, Asahiro Morishita, Joji Tani & Tsutomu Masaki
Pages: 1279-1298
Published online: 14 Dec 2022
AbstractforAntitumor Effects and Mechanisms of Metabolic Syndrome Medications on Hepatocellular Carcinoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 204 Views
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ORIGINAL RESEARCH

Article
Advanced Hepatocellular Carcinoma in Adults Without Cirrhosis: A Single-Institution Retrospective Review
Ellery Altshuler, Raymond Richhart, Mahmoud Aryan, William King, Kelsey Pan, Akash Mathavan, Akshay Mathavan, Diana Rodriguez, Bishal Paudel, Nathan Northern, Brian Ramnaraign, Ilyas Sahin & Jesus C Fabregas
Pages: 1299-1307
Published online: 19 Dec 2022
AbstractforAdvanced Hepatocellular Carcinoma in Adults Without Cirrhosis: A Single-Institution Retrospective Review | Full Text | References | PDF (1.2 MB) | EPUB
  • 92 Views
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Article
Comparison of the Efficacy and Safety of Transarterial Chemoembolization Plus Microwave Ablation versus Surgical Resection in Patients with Solitary Large Hepatocellular Carcinoma: A Propensity Score-Matched Analysis
Yongchao Zhang, Hualei Chen, Shanshan Chen, Youjia Duan, Long Cheng, Jie Gao & Wei Li
Pages: 1309-1321
Published online: 19 Dec 2022
AbstractforComparison of the Efficacy and Safety of Transarterial Chemoembolization Plus Microwave Ablation versus Surgical Resection in Patients with Solitary Large Hepatocellular Carcinoma: A Propensity Score-Matched Analysis | Full Text | References | PDF (2.3 MB) | EPUB
  • 99 Views
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Article
Validation of Hepatocellular Carcinoma Risk Prediction Models in Patients with Hepatitis B-Related Cirrhosis
Ran Cheng & Xiaoyuan Xu
Pages: 987-997
Published online: 12 Sep 2022
AbstractforValidation of Hepatocellular Carcinoma Risk Prediction Models in Patients with Hepatitis B-Related Cirrhosis | Full Text | References | PDF (1.9 MB) | EPUB
  • 110 Views
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Article
ARFIP2 Regulates EMT and Autophagy in Hepatocellular Carcinoma in Part Through the PI3K/Akt Signalling Pathway
Kaida Huang, Yubiao Lin, Keyin Wang, Jianfen Shen & Dahai Wei
Pages: 1323-1339
Published online: 20 Dec 2022
AbstractforARFIP2 Regulates EMT and Autophagy in Hepatocellular Carcinoma in Part Through the PI3K/Akt Signalling Pathway | Full Text | References | PDF (14 MB) | EPUB
  • 125 Views
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Article
Nrf2-siRNA Enhanced the Anti-Tumor Effects of As2O3 in 5-Fluorouracil-Resistant Hepatocellular Carcinoma by Inhibiting HIF-1α/HSP70 Signaling
Xuhua Duan, Wenze Xu, Hao Li, Manzhou Wang, Wenhui Wang, Huibin Lu, Yancang Zhang & Xinwei Han
Pages: 1341-1352
Published online: 21 Dec 2022
AbstractforNrf2-siRNA Enhanced the Anti-Tumor Effects of As2O3 in 5-Fluorouracil-Resistant Hepatocellular Carcinoma by Inhibiting HIF-1α/HSP70 Signaling | Full Text | References | PDF (10.4 MB) | EPUB
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Hepatectomy After Conversion Therapy for Initially Unresectable HCC: What is the Difference?
Laihui Luo, Yongzhu He, Guoqing Zhu, Yongqiang Xiao, Shengjiang Song, Xian Ge, Tao Wang, Jin Xie, Wei Deng, Zhigao Hu & Renfeng Shan
Pages: 1353-1368
Published online: 22 Dec 2022
AbstractforHepatectomy After Conversion Therapy for Initially Unresectable HCC: What is the Difference? | Full Text | References | PDF (4.3 MB) | EPUB
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Sulfatase 2 Along with Syndecan 1 and Glypican 3 Serum Levels are Associated with a Prognostic Value in Patients with Alcoholic Cirrhosis-Related Advanced Hepatocellular Carcinoma
Nesrine Mouhoubi, Jessica Bamba-Funck, Angela Sutton, Lorraine Blaise, Olivier Seror, Nathalie Ganne-Carrié, Marianne Ziol, Gisèle N’Kontchou, Nathalie Charnaux, Pierre Nahon, Jean-Charles Nault & Erwan Guyot
Pages: 1369-1383
Published online: 28 Dec 2022
AbstractforSulfatase 2 Along with Syndecan 1 and Glypican 3 Serum Levels are Associated with a Prognostic Value in Patients with Alcoholic Cirrhosis-Related Advanced Hepatocellular Carcinoma | Full Text | References | PDF (4.5 MB) | EPUB
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Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses
Chu-Yu Huang, Zih-Yin Lai, Tzu-Jung Hsu, Fong-In Chou, Hong-Ming Liu & Yung-Jen Chuang
Pages: 1385-1401
Published online: 29 Dec 2022
AbstractforBoron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses | Full Text | References | PDF (9.6 MB) | EPUB
  • 207 Views
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Development and Validation of Prognostic Nomograms for Hepatocellular Carcinoma After Hepatectomy Based on Inflammatory Markers
Zili Hu, Yu Yuan, Zhiwen Hu, Qingbo Liu, Yizhen Fu, Jingyu Hou, Xuqi Sun, Shaoqiang Li, Wenbin Duan & Minshan Chen
Pages: 1403-1413
Published online: 29 Dec 2022
AbstractforDevelopment and Validation of Prognostic Nomograms for Hepatocellular Carcinoma After Hepatectomy Based on Inflammatory Markers | Full Text | References | PDF (665.2 KB) | EPUB
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The Clinical Relevance and Immune Correlation of SLC10 Family Genes in Liver Cancer
Shan Tian, Jiao Li, Jiankang Xiang & Pailan Peng
Pages: 1415-1431
Published online: 30 Dec 2022
AbstractforThe Clinical Relevance and Immune Correlation of SLC10 Family Genes in Liver Cancer | Full Text | References | PDF (14.3 MB) | EPUB
  • 133 Views
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Repeated Measurement of FIB-4 to Predict Long-Term Risk of HCC Development Up to 10 Years After SVR
Yanzheng Zou, Ming Yue, Linna Jia, Yidi Wang, Hongbo Chen, Yifan Wang, Meiling Zhang, Yue Feng, Rongbin Yu, Sheng Yang & Peng Huang
Pages: 1433-1443
Published online: 30 Dec 2022
AbstractforRepeated Measurement of FIB-4 to Predict Long-Term Risk of HCC Development Up to 10 Years After SVR | Full Text | References | PDF (802.4 KB) | EPUB
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