Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China

Figures & data

Table 1 Off-label usage with Gendicine in China

Type of tumor	Number of patients	Administration routes	Combination with other therapies	Reference
Hepatocellular carcinoma	68	CT-guided intratumor injection	Chemotherapy	Guan et al 2005
Lung cancer	15	CT-guided pneumocentesis	None	Weng et al 2004
	15	CT-guided pneumocentesis or via bronchial artery	Chemotherapy	Guan et al 2005
Soft tissue sarcoma	12	Intratumor injection	Hyperthermia	Xiao et al 2007
Malignant effusions by malignant mesothelioma and alimentary tract carcinoma	32	Peritoneal injection	Hyperthermia	Liu et al 2006

Abbreviation: CT, computed tomography.

GuanYSSunLZhouXP2005Combination therapy with recombinant adenovirus-p53 injection (rAd-p53) via transcatheter hepatic arterial chemoembolization for advanced hepatic carcinomaShijie Huaren Xiaohua Zazhi131257

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WengZQinTLTanSY2004Clinical trial for the treatment of advanced lung cancer by intratumoral injection of rAd p53Shenzhen Zhong Xi Yi Jie He Za Zhi1420610

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XiaoSLiuCSunY2007Clinical observation of the effect of recombinant adenovirus- p53 plus radio-thermotherapy on soft tissue sarcomaZhong Guo Zhong Liu Lin Chuang34657

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