Figures & data
Figure 1. The induction of senescence promotes FAS upregulation via NFκB as well as the release of chemokines (blue diamonds) that recruit cells of the innate immune system. In addition, senescence results in the secretion of cytokines (red and yellow dots) that act locally within autocrine and paracrine loops, hence sustaining the senescent phenotype and promoting the killing of senescent cells by the immune system.
