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Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 4
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Research Article

Prediction of metabolic clearance using fresh human hepatocytes: Comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines

D. Hallifax Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, M13 9PT, UK
,
A. Galetin Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, M13 9PT, UK
&
J. B. Houston Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, M13 9PT, UK
Pages 353-367 | Received 29 Nov 2007, Accepted 29 Nov 2007, Published online: 22 Sep 2008

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