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Drug Delivery Volume 24, 2017 - Issue 1
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Research Article

Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine

Nina Henrya INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; ;b Institut des Matériaux Jean Rouxel (IMN), Université de Nantes, CNRS, Nantes, France; ;c UFR Odontologie, Université de Nantes, Nantes, France; View further author information
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Johann Cloueta INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; ;c UFR Odontologie, Université de Nantes, Nantes, France; ;d CHU Nantes, PHU 11 Pharmacie, Pharmacie Centrale, Nantes, France; ;e UFR Sciences Biologiques et Pharmaceutiques, Université de Nantes, Nantes, France; View further author information
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Audrey Fragalea INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; ;c UFR Odontologie, Université de Nantes, Nantes, France; View further author information
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Louise Griveaua INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; View further author information
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Claire Chédevillea INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; View further author information
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Joëlle Véziersa INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; ;c UFR Odontologie, Université de Nantes, Nantes, France; ;f SC3M platform, UMS INSERM 016/CNRS 3556, SFR François Bonamy, Nantes, France; ;g CHU Nantes, PHU 4 OTONN, Nantes, France; View further author information
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Pierre Weissc UFR Odontologie, Université de Nantes, Nantes, France; ;h INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team REGOS “Regenerative Medicine of Bone Tissues”, Nantes, FranceView further author information
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Jean Le Bideaub Institut des Matériaux Jean Rouxel (IMN), Université de Nantes, CNRS, Nantes, France; View further author information
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Jérôme Guicheuxa INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; ;c UFR Odontologie, Université de Nantes, Nantes, France; ;g CHU Nantes, PHU 4 OTONN, Nantes, France; View further author information
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Catherine Le Visagea INSERM, UMRS 1229, RMeS “Regenerative Medicine and Skeleton”, Team STEP “Skeletal Physiopathology and Joint Regenerative Medicine”, Nantes, France; ;c UFR Odontologie, Université de Nantes, Nantes, France; Correspondence[email protected]
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Pages 999-1010 | Received 03 May 2017, Accepted 06 Jun 2017, Published online: 23 Jun 2017

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