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Expert Opinion on Drug Discovery Volume 13, 2018 - Issue 6
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Review

Bundling arrows: improving translational CNS drug development by integrated PK/PD-metabolomics

W. J. van den BrinkDivision of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The NetherlandsORCID Iconhttp://orcid.org/0000-0002-4493-2382View further author information
ORCID Icon,
T. HankemeierDivision of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The NetherlandsView further author information
,
P. H. van der GraafDivision of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands;Certara QSP, Canterbury Innovation House, Canterbury, United KingdomView further author information
&
E. C. M. de LangeDivision of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The NetherlandsCorrespondence[email protected]
View further author information
Pages 539-550 | Received 01 Nov 2017, Accepted 26 Feb 2018, Published online: 08 Mar 2018

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