Expert Opinion on Drug Discovery, Volume 13, Issue 6 (2018)

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Expert Opinion on Drug Discovery, Volume 13, Issue 6 (2018)

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Editorial

Editorial
Evolving models of collaborative drug discovery: managing intellectual capital assets
Minna Allarakhia
Pages: 473-476
Published online: 23 Mar 2018
First Page PreviewforEvolving models of collaborative drug discovery: managing intellectual capital assets | Full Text | References | PDF (467.2 KB)
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Free Access

Review

Review
Novel drug discovery strategies for atherosclerosis that target necrosis and necroptosis
Isabelle Coornaert, Sam Hofmans, Lars Devisscher, Koen Augustyns, Pieter Van Der Veken, Guido R.Y. De Meyer & Wim Martinet
Pages: 477-488
Published online: 29 Mar 2018
AbstractforNovel drug discovery strategies for atherosclerosis that target necrosis and necroptosis | Full Text | References | PDF (1.3 MB)
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Review
Current and potential targets for drug design in the androgen receptor pathway for prostate cancer
Achuta Kumar Guddati
Pages: 489-496
Published online: 06 Apr 2018
AbstractforCurrent and potential targets for drug design in the androgen receptor pathway for prostate cancer | Full Text | References | PDF (802.2 KB)
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Review
Overcoming problems of poor drug penetration into bacteria: challenges and strategies for medicinal chemists
Davide Benedetto Tiz, Danijel Kikelj & Nace Zidar
Pages: 497-507
Published online: 23 Mar 2018
AbstractforOvercoming problems of poor drug penetration into bacteria: challenges and strategies for medicinal chemists | Full Text | References | PDF (1.2 MB)
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Review
Computational modeling of human oral bioavailability: what will be next?
Miguel Ángel Cabrera-Pérez & Hai Pham-The
Pages: 509-521
Published online: 17 Apr 2018
AbstractforComputational modeling of human oral bioavailability: what will be next? | Full Text | References | PDF (1.5 MB)
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Review
Have there been improvements in Alzheimer’s disease drug discovery over the past 5 years?
Ramón Cacabelos
Pages: 523-538
Published online: 01 Apr 2018
AbstractforHave there been improvements in Alzheimer’s disease drug discovery over the past 5 years? | Full Text | References | PDF (1.2 MB)
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Review
Bundling arrows: improving translational CNS drug development by integrated PK/PD-metabolomics
W. J. van den Brink, T. Hankemeier, P. H. van der Graaf & E. C. M. de Lange
Pages: 539-550
Published online: 08 Mar 2018
AbstractforBundling arrows: improving translational CNS drug development by integrated PK/PD-metabolomics | Full Text | References | PDF (1.6 MB)
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Open Access
Review
Murine models of psoriasis and their usefulness for drug discovery
Shih-Yi Chuang, Chih-Hung Lin, Calvin T. Sung & Jia-You Fang
Pages: 551-562
Published online: 17 Apr 2018
AbstractforMurine models of psoriasis and their usefulness for drug discovery | Full Text | References | PDF (1.1 MB)
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Drug Discovery Case History

Article
The discovery and development of aclidinium bromide for the treatment of chronic obstructive pulmonary disease
Mario Malerba, Alessandro Radaeli, Giuseppe Santini, Jaymin Morjaria, Nadia Mores, Chiara Mondino, Giuseppe Macis & Paolo Montuschi
Pages: 563-577
Published online: 04 Apr 2018
AbstractforThe discovery and development of aclidinium bromide for the treatment of chronic obstructive pulmonary disease | Full Text | References | PDF (1.2 MB)
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