Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms

Claudia A. Castro JaramilloRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Sara BelliRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Anne-Christine CascaisRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Sherri DudalUCB Celltech, Slough, UK

Martin R. EdelmannRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Markus HaakRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Marie-Elise BrunRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Michael B. OttenederRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Mohammed UllahRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Christoph FunkRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Franz SchulerRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland

Silke SimonRoche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, SwitzerlandCorrespondence[email protected]

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