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mAbs Volume 12, 2020 - Issue 1
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A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease model

Songmao Zhenga Biologics Development Sciences, Janssen BioTherapeutics (JBIO), Spring House, PA, USA
,
Jin Niua Biologics Development Sciences, Janssen BioTherapeutics (JBIO), Spring House, PA, USA;b Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA
,
Brian Geista Biologics Development Sciences, Janssen BioTherapeutics (JBIO), Spring House, PA, USA
,
Damien Finka Biologics Development Sciences, Janssen BioTherapeutics (JBIO), Spring House, PA, USA
,
Zhenhua Xuc Clinical Pharmacology and Pharmacometrics, Quantitative Sciences, Spring House, PA, USA
,
Honghui Zhouc Clinical Pharmacology and Pharmacometrics, Quantitative Sciences, Spring House, PA, USA
&
Weirong Wangc Clinical Pharmacology and Pharmacometrics, Quantitative Sciences, Spring House, PA, USACorrespondence[email protected]
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Article: 1813962 | Received 25 May 2020, Accepted 19 Aug 2020, Published online: 24 Sep 2020

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