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Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
Peng Zhaoa Brown Foundation Institute of Molecular Medicine, Texas Therapeutics Institute, University of Texas Health Science Center at Houston, Houston, Texas, USAView further author information
, Yuanzhong Xub Center for Metabolic and Degenerative Diseases, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USAView further author information
, Xuejun Fana Brown Foundation Institute of Molecular Medicine, Texas Therapeutics Institute, University of Texas Health Science Center at Houston, Houston, Texas, USAView further author information
, Leike Lia Brown Foundation Institute of Molecular Medicine, Texas Therapeutics Institute, University of Texas Health Science Center at Houston, Houston, Texas, USAView further author information
, Xin Lia Brown Foundation Institute of Molecular Medicine, Texas Therapeutics Institute, University of Texas Health Science Center at Houston, Houston, Texas, USAView further author information
, Hisashi Arasec Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Suita, JapanView further author information
, Qingchun Tongb Center for Metabolic and Degenerative Diseases, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USAView further author information
, Ningyan Zhanga Brown Foundation Institute of Molecular Medicine, Texas Therapeutics Institute, University of Texas Health Science Center at Houston, Houston, Texas, USACorrespondence[email protected]
View further author information
& View further author information
Zhiqiang Ana Brown Foundation Institute of Molecular Medicine, Texas Therapeutics Institute, University of Texas Health Science Center at Houston, Houston, Texas, USACorrespondence[email protected]
https://orcid.org/0000-0001-9309-2335View further author information
Article: 2107971
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Received 18 May 2022, Accepted 27 Jul 2022, Published online: 03 Aug 2022
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