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Expert Opinion on Investigational Drugs Volume 14, 2005 - Issue 9
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Key Paper Evaluation

Rho-kinase inhibitors show promise in pulmonary hypertension

NAGAOKA T, FAGAN KA, GEBB SA et al.: Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. Am. J. Respir. Crit. Care Med. (2005) 171:494-499. FUKUMOTO Y, MATOBA T, ITO A et al.: Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart (2005) 91:391-392.

Sheila A Doggrell Division of Health Practice, Auckland University of Technology – Akoranga Campus, Northcote, Auckland, New Zealand. [email protected]
Pages 1157-1159 | Published online: 22 Aug 2005

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