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Original Research
Safety, tolerability, pharmacokinetics, and pharmacodynamics of novel glucokinase activator HMS5552: results from a first-in-human single ascending dose study
Hongrong Xu1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
, Lei Sheng1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
, Weili Chen1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
, Fei Yuan1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
, Mengjie Yang1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
, Hui Li1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
, Xuening Li1 Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
, John Choi2 Department of Clinical Research & Development, Hua Medicine, Shanghai, People’s Republic of China
, Guiyu Zhao2 Department of Clinical Research & Development, Hua Medicine, Shanghai, People’s Republic of China
, Tianxin Hu2 Department of Clinical Research & Development, Hua Medicine, Shanghai, People’s Republic of China
, Yongguo Li2 Department of Clinical Research & Development, Hua Medicine, Shanghai, People’s Republic of China
, Yi Zhang2 Department of Clinical Research & Development, Hua Medicine, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
& Li Chen2 Department of Clinical Research & Development, Hua Medicine, Shanghai, People’s Republic of China
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Pages 1619-1626
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Published online: 09 May 2016
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