Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer

Armando Lucero-Acuña1 Department of Chemical and Environmental Engineering, University of Arizona, Tucson, AZ, USA

Justin J Jeffery2 Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA

Edward R Abril3 University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA;4 Department of Pathology, University of Arizona, Tucson, AZ, USA

Raymond B Nagle3 University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA;4 Department of Pathology, University of Arizona, Tucson, AZ, USA

Roberto Guzman1 Department of Chemical and Environmental Engineering, University of Arizona, Tucson, AZ, USA

Mark D Pagel2 Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA;3 University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA;5 Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA;6 Department of Medical Imaging, University of Arizona, Tucson, AZ, USA

Emmanuelle J Meuillet3 University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA;7 Department of Molecular and Cell Biology, University of Arizona, Tucson, AZ, USA;8 Department of Nutritional Sciences, University of Arizona, Tucson, AZ, USACorrespondence[email protected]

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Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer

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Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer

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