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Original Research
IL-6 −572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study
Matias F Martinez1 Laboratory of Chemical Carcinogenesis and Pharmacogenetics (CQF), Department of Basic and Clinical Oncology (DOBC), Faculty of Medicine, University of Chile, Santiago, Chile;2 Latin American Network for the Implementation and Validation of Pharmacogenomic Clinical Guidelines (RELIVAF-CYTED), Madrid, Spainhttps://orcid.org/0000-0003-0498-6447
, Enzo Alveal1 Laboratory of Chemical Carcinogenesis and Pharmacogenetics (CQF), Department of Basic and Clinical Oncology (DOBC), Faculty of Medicine, University of Chile, Santiago, Chile
, Tomas G Soto1 Laboratory of Chemical Carcinogenesis and Pharmacogenetics (CQF), Department of Basic and Clinical Oncology (DOBC), Faculty of Medicine, University of Chile, Santiago, Chile;3 Departamento De Ciencias Básicas Santiago, Facultad De Ciencias, Universidad Santo Tomás, Santiago, Chile
, Eva I Bustamante4 Cancer Institute Arturo López Pérez Foundation, Santiago, Chilehttps://orcid.org/0000-0002-3125-8608
, Fernanda Ávila5 Infectology Section, Medicine Department, Clinical Hospital of the University of Chile, Santiago, Chile
, Shrikant I Bangdiwala6 Population Health Research Institute, McMaster University, Hamilton, ON, Canada;7 Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada
, Ivonne Flores4 Cancer Institute Arturo López Pérez Foundation, Santiago, Chile
, Claudia Benavides4 Cancer Institute Arturo López Pérez Foundation, Santiago, Chile
, Ricardo Morales4 Cancer Institute Arturo López Pérez Foundation, Santiago, Chilehttps://orcid.org/0000-0003-4784-9872
, Nelson M Varela1 Laboratory of Chemical Carcinogenesis and Pharmacogenetics (CQF), Department of Basic and Clinical Oncology (DOBC), Faculty of Medicine, University of Chile, Santiago, Chile;2 Latin American Network for the Implementation and Validation of Pharmacogenomic Clinical Guidelines (RELIVAF-CYTED), Madrid, Spainhttps://orcid.org/0000-0002-5229-3007
& Luis A Quiñones1 Laboratory of Chemical Carcinogenesis and Pharmacogenetics (CQF), Department of Basic and Clinical Oncology (DOBC), Faculty of Medicine, University of Chile, Santiago, Chile;2 Latin American Network for the Implementation and Validation of Pharmacogenomic Clinical Guidelines (RELIVAF-CYTED), Madrid, SpainCorrespondence[email protected] [email protected]
https://orcid.org/0000-0002-7967-5320
show allhttps://orcid.org/0000-0002-7967-5320
Pages 337-343
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Published online: 19 Aug 2020
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