Pharmacogenomics and Personalized Medicine, Volume 13, Issue (2020)

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Pharmacogenomics and Personalized Medicine, Volume 13, Issue (2020)

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Original Research

Article
Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine
Monpat Chamnanphon, Andrea Gaedigk, Apichaya Puangpetch, Ekawat Pasomsub, Wasun Chantratita, Rhea J Longley, Jetsumon Sattabongkot, Pajaree Chariyavilaskul & Chonlaphat Sukasem
Pages: 1-12
Published online: 22 Dec 2022
AbstractforPharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine | Full Text | References | PDF (1.7 MB) | EPUB
  • 131 Views
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Open Access
Article
The Effect of UGT1A9, CYP2B6 and CYP2C9 Genes Polymorphism on Propofol Pharmacokinetics in Children
Dimitrije Pavlovic, Ivana Budic, Tatjana Jevtovic Stoimenov, Dragana Stokanovic, Vesna Marjanovic, Marija Stevic, Milan Slavkovic & Dusica Simic
Pages: 13-27
Published online: 17 Jan 2020
AbstractforThe Effect of UGT1A9, CYP2B6 and CYP2C9 Genes Polymorphism on Propofol Pharmacokinetics in Children | Full Text | References | PDF (2.5 MB) | EPUB
  • 189 Views
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Open Access
Article
CYP2C19*17 May Increase the Risk of Death Among Patients with an Acute Coronary Syndrome and Non-Valvular Atrial Fibrillation Who Receive Clopidogrel and Rivaroxaban
DA Sychev, OA Baturina, KB Mirzaev, E Rytkin, DV Ivashchenko, DA Andreev, KA Ryzhikova, EA Grishina, PO Bochkov & RV Shevchenko
Pages: 29-37
Published online: 22 Dec 2022
AbstractforCYP2C19*17 May Increase the Risk of Death Among Patients with an Acute Coronary Syndrome and Non-Valvular Atrial Fibrillation Who Receive Clopidogrel and Rivaroxaban | Full Text | References | PDF (652 KB) | EPUB
  • 153 Views
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Open Access

Review

Review Article
Towards Precision Medicine in Systemic Lupus Erythematosus
Elliott Lever, Marta R Alves & David A Isenberg
Pages: 39-49
Published online: 04 Feb 2020
AbstractforTowards Precision Medicine in Systemic Lupus Erythematosus | Full Text | References | PDF (384.5 KB) | EPUB
  • 362 Views
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Open Access

Original Research

Article
HMGA2 Polymorphisms and Hepatoblastoma Susceptibility: A Five-Center Case-Control Study
Li Li, Zhenjian Zhuo, Zhen Yang, Jinhong Zhu, Xiaoli He, Zhonghua Yang, Jiao Zhang, Yijuan Xin, Jing He & Tiesong Zhang
Pages: 51-57
Published online: 22 Dec 2022
AbstractforHMGA2 Polymorphisms and Hepatoblastoma Susceptibility: A Five-Center Case-Control Study | Full Text | References | PDF (370.7 KB) | EPUB
  • 110 Views
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Open Access

Case Report

Case Report
A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions
Carlos Alberto Calderon-Ospina, Mario Hernández-Sómerson, Ana María García, Adriana Mejia, Caroll Tamayo-Agudelo, Paul Laissue & Dora Janeth Fonseca Mendoza
Pages: 59-70
Published online: 22 Dec 2022
AbstractforA Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions | Full Text | References | PDF (3.8 MB) | EPUB
  • 180 Views
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Open Access

Original Research

Article
Sex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid Analgesics
Guilherme S Lopes, Suzette J Bielinski, Ann M Moyer, John Logan Black III, Debra J Jacobson, Ruoxiang Jiang, Nicholas B Larson & Jennifer L St Sauver
Pages: 71-79
Published online: 13 Mar 2020
AbstractforSex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid Analgesics | Full Text | References | PDF (1 MB) | EPUB
  • 179 Views
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Open Access
Article
ADAM17 Genetic Variants and the Response of TNF-α Inhibitor in Rheumatoid Arthritis Patients
Hyun Jeong Kim, Nga Thi Trinh, Yunjeong Choi, Woorim Kim, Kyung Hyun Min, Sang Oh Kang, Joo Hee Kim, Hyoun-Ah Kim, Ju-Yang Jung, In Ah Choi & Kyung Eun Lee
Pages: 81-88
Published online: 16 Mar 2020
AbstractforADAM17 Genetic Variants and the Response of TNF-α Inhibitor in Rheumatoid Arthritis Patients | Full Text | References | PDF (767.8 KB) | EPUB
  • 109 Views
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Open Access

Review

Review Article
Pharmacogenetics of Pediatric Asthma: Current Perspectives
Javier Perez-Garcia, Antonio Espuela-Ortiz, Fabian Lorenzo-Diaz & Maria Pino-Yanes
Pages: 89-103
Published online: 18 Mar 2020
AbstractforPharmacogenetics of Pediatric Asthma: Current Perspectives | Full Text | References | PDF (569.9 KB) | EPUB
  • 398 Views
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Open Access
Review Article
On the Role of Artificial Intelligence in Genomics to Enhance Precision Medicine
Óscar Álvarez-Machancoses, Enrique J DeAndrés Galiana, Ana Cernea, J Fernández de la Viña & Juan Luis Fernández-Martínez
Pages: 105-119
Published online: 19 Mar 2020
AbstractforOn the Role of Artificial Intelligence in Genomics to Enhance Precision Medicine | Full Text | References | PDF (6.4 MB) | EPUB
  • 1403 Views
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Open Access

Original Research

Article
Association Between lncRNA HULC rs7763881 Polymorphism and Gastric Cancer Risk
Jang Hee Hong, Eun-Heui Jin, In Ae Chang, Hyojin Kang, Sang-Il Lee & Jae Kyu Sung
Pages: 121-126
Published online: 22 Dec 2022
AbstractforAssociation Between lncRNA HULC rs7763881 Polymorphism and Gastric Cancer Risk | Full Text | References | PDF (451 KB) | EPUB
  • 105 Views
  • 1 CrossRef citations
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Open Access

Review

Review Article
Challenges and Future Prospects of Precision Medicine in Psychiatry
Mirko Manchia, Claudia Pisanu, Alessio Squassina & Bernardo Carpiniello
Pages: 127-140
Published online: 22 Dec 2022
AbstractforChallenges and Future Prospects of Precision Medicine in Psychiatry | Full Text | References | PDF (1.2 MB) | EPUB
  • 1410 Views
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Open Access

Original Research

Article
Effects of CYP3A5 Polymorphisms on Efficacy and Safety of Tacrolimus Therapy in Patients with Idiopathic Membranous Nephropathy
Chengning Zhang, Suyan Duan, Miao Guo, Yanggang Yuan, Zhimin Huang, Jingfeng Zhu, Bin Sun, Bo Zhang & Changying Xing
Pages: 141-149
Published online: 22 Dec 2022
AbstractforEffects of CYP3A5 Polymorphisms on Efficacy and Safety of Tacrolimus Therapy in Patients with Idiopathic Membranous Nephropathy | Full Text | References | PDF (323.6 KB) | EPUB
  • 105 Views
  • 2 CrossRef citations
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Open Access
Article
Negative Association Between lncRNA HOTTIP rs3807598 C>G and Hirschsprung Disease
Yi Zheng, Zhenjian Zhuo, Xiaoli Xie, Lifeng Lu, Qiuming He & Wei Zhong
Pages: 151-156
Published online: 22 Dec 2022
AbstractforNegative Association Between lncRNA HOTTIP rs3807598 C>G and Hirschsprung Disease | Full Text | References | PDF (248.2 KB) | EPUB
  • 86 Views
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Open Access
Article
Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility
Bingqi Wang, Min Wang, Xianping Li, Min Yang & Lei Liu
Pages: 157-165
Published online: 22 Dec 2022
AbstractforVariations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility | Full Text | References | PDF (1.9 MB) | EPUB
  • 162 Views
  • 6 CrossRef citations
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Open Access

Review

Review Article
Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review
Mohammad Jamshidi, Somayeh Mohammadi Pour & Mohammad-Reza Mahmoudian-Sani
Pages: 167-180
Published online: 22 Dec 2022
AbstractforSingle Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review | Full Text | References | PDF (476.6 KB) | EPUB
  • 161 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Association Between CYP17A1, CYB5A Polymorphisms and Efficacy of Abiraterone Acetate/Prednisone Treatment in Castration-Resistant Prostate Cancer Patients
Xiang Wu, Qing-Jiang Xu, Ping-Zhou Chen, Chen-Bo Yu, Lie-Fu Ye & Tao Li
Pages: 181-188
Published online: 22 Dec 2022
AbstractforAssociation Between CYP17A1, CYB5A Polymorphisms and Efficacy of Abiraterone Acetate/Prednisone Treatment in Castration-Resistant Prostate Cancer Patients | Full Text | References | PDF (1.5 MB) | EPUB
  • 113 Views
  • 1 CrossRef citations
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Open Access
Article
Association Study of MAP3K1 SNPs and Risk Factors with Susceptibility to Esophageal Squamous Cell Carcinoma in a Chinese Population: A Case–Control Study
Yiling Yang, Qiang Zhou, Huiwen Pan, Liming Wang & Cheng Qian
Pages: 189-197
Published online: 17 Nov 2022
AbstractforAssociation Study of MAP3K1 SNPs and Risk Factors with Susceptibility to Esophageal Squamous Cell Carcinoma in a Chinese Population: A Case–Control Study | Full Text | References | PDF (336.4 KB) | EPUB
  • 94 Views
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Open Access
Article
Analysis of Comprehensive Pharmacogenomic Profiling of VIP Variants Among the Genetically Isolated Chechen Subpopulation from Jordan
Laith N AL-Eitan, Doaa M Rababa’h, Nancy M Hakooz, Mansour A Alghamdi & Rana B Dajani
Pages: 199-215
Published online: 17 Nov 2022
AbstractforAnalysis of Comprehensive Pharmacogenomic Profiling of VIP Variants Among the Genetically Isolated Chechen Subpopulation from Jordan | Full Text | References | PDF (497.2 KB) | EPUB
  • 97 Views
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Open Access
Article
Development of Customizable Implementation Guides to Support Clinical Adoption of Pharmacogenomics: Experiences of the Implementing GeNomics In pracTicE (IGNITE) Network
Benjamin Q Duong, Meghan J Arwood, J Kevin Hicks, Amber L Beitelshees, Francesco Franchi, John T Houder, Nita A Limdi, Kelsey J Cook, Aniwaa Owusu Obeng, Natasha Petry, Sony Tuteja, Amanda R Elsey, Larisa H Cavallari, Kristin Wiisanen & on behalf of the IGNITE Network
Pages: 217-226
Published online: 17 Nov 2022
AbstractforDevelopment of Customizable Implementation Guides to Support Clinical Adoption of Pharmacogenomics: Experiences of the Implementing GeNomics In pracTicE (IGNITE) Network | Full Text | References | PDF (768.7 KB) | EPUB
  • 164 Views
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Open Access

Review

Review Article
Comparison of Patient Susceptibility Genes Across Breast Cancer: Implications for Prognosis and Therapeutic Outcomes
Shira Peleg Hasson, Tehillah Menes & Amir Sonnenblick
Pages: 227-238
Published online: 17 Nov 2022
AbstractforComparison of Patient Susceptibility Genes Across Breast Cancer: Implications for Prognosis and Therapeutic Outcomes | Full Text | References | PDF (1.3 MB) | EPUB
  • 222 Views
  • 6 CrossRef citations
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Open Access
Review Article
Clinical Utility of CYP2C19 Genotype-Guided Antiplatelet Therapy in Patients at Risk of Adverse Cardiovascular and Cerebrovascular Events: A Review of Emerging Evidence
Megan N Gower, Lindsay R Ratner, Alexis K Williams, Joseph S Rossi, George A Stouffer & Craig R Lee
Pages: 239-252
Published online: 17 Nov 2022
AbstractforClinical Utility of CYP2C19 Genotype-Guided Antiplatelet Therapy in Patients at Risk of Adverse Cardiovascular and Cerebrovascular Events: A Review of Emerging Evidence | Full Text | References | PDF (2.2 MB) | EPUB
  • 210 Views
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Open Access

Original Research

Article
Genetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet’s Disease in Saudi Population
Fahdah Al Okaily, Seham Alrashidi, Mohammad Mustafa & Faris Bander Alrashdan
Pages: 253-259
Published online: 17 Nov 2022
AbstractforGenetic Polymorphisms in Transforming Growth Factor-β, Interferon-γ and Interleukin-6 Genes and Susceptibility to Behcet’s Disease in Saudi Population | Full Text | References | PDF (3.2 MB) | EPUB
  • 118 Views
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Open Access

Review

Review Article
Pharmacogenomic Response of Inhaled Corticosteroids for the Treatment of Asthma: Considerations for Therapy
Mario Cazzola, Paola Rogliani, Luigino Calzetta & Maria Gabriella Matera
Pages: 261-271
Published online: 17 Nov 2022
AbstractforPharmacogenomic Response of Inhaled Corticosteroids for the Treatment of Asthma: Considerations for Therapy | Full Text | References | PDF (359.1 KB) | EPUB
  • 375 Views
  • 2 CrossRef citations
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Open Access

Original Research

Article
Polymorphism of XRCC3 in Egyptian Breast Cancer Patients
Mona Khyri Alkasaby, Abeer Ibrahim Abd El-Fattah, Iman Hassan Ibrahim & Hesham Samir Abd El-Samie
Pages: 273-282
Published online: 06 Aug 2020
AbstractforPolymorphism of XRCC3 in Egyptian Breast Cancer Patients | Full Text | References | PDF (2.9 MB) | EPUB
  • 168 Views
  • 2 CrossRef citations
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Open Access
Article
miR-100 rs1834306 A>G Increases the Risk of Hirschsprung Disease in Southern Chinese Children
Yun Zhu, Ao Lin, Yi Zheng, Xiaoli Xie, Qiuming He & Wei Zhong
Pages: 283-288
Published online: 10 Aug 2020
AbstractformiR-100 rs1834306 A>G Increases the Risk of Hirschsprung Disease in Southern Chinese Children | Full Text | References | PDF (273 KB) | EPUB
  • 98 Views
  • 3 CrossRef citations
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Open Access

Short Report

Brief Report
CYP2D6 Expression in Veterans Experiencing Opioid Overdose: A Postmortem Review
Julia Boyle & Christopher J Stock
Pages: 289-293
Published online: 11 Aug 2020
AbstractforCYP2D6 Expression in Veterans Experiencing Opioid Overdose: A Postmortem Review | Full Text | References | PDF (238.3 KB) | EPUB
  • 107 Views
  • 1 CrossRef citations
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Open Access

Review

Review Article
Implementation of Pharmacogenetics to Individualize Treatment Regimens for Children with Acute Lymphoblastic Leukemia
Dimitri Maamari, Habib El-Khoury, Omran Saifi, Samar A Muwakkit & Nathalie K Zgheib
Pages: 295-317
Published online: 12 Aug 2020
AbstractforImplementation of Pharmacogenetics to Individualize Treatment Regimens for Children with Acute Lymphoblastic Leukemia | Full Text | References | PDF (4 MB) | EPUB
  • 305 Views
  • 7 CrossRef citations
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Open Access

Original Research

Article
CHRM3 rs2165870 Polymorphism Correlates with Postoperative Nausea and Vomiting Incidence and the Efficacy of Ondansetron in a Chinese Han Population
Jiayu Wang, Yang Li, Cuijuan Zheng, Yan Sun & Jianping Yang
Pages: 319-326
Published online: 13 Aug 2020
AbstractforCHRM3 rs2165870 Polymorphism Correlates with Postoperative Nausea and Vomiting Incidence and the Efficacy of Ondansetron in a Chinese Han Population | Full Text | References | PDF (289.5 KB) | EPUB
  • 115 Views
  • 1 CrossRef citations
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Open Access
Article
Association Between Vitamin D Receptor Gene Polymorphism rs2228570 and Allergic Rhinitis
Wei Zhang & Yu Xu
Pages: 327-335
Published online: 17 Nov 2022
AbstractforAssociation Between Vitamin D Receptor Gene Polymorphism rs2228570 and Allergic Rhinitis | Full Text | References | PDF (618.6 KB) | EPUB
  • 217 Views
  • 4 CrossRef citations
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Open Access
Article
IL-6 −572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study
Matias F Martinez, Enzo Alveal, Tomas G Soto, Eva I Bustamante, Fernanda Ávila, Shrikant I Bangdiwala, Ivonne Flores, Claudia Benavides, Ricardo Morales, Nelson M Varela & Luis A Quiñones
Pages: 337-343
Published online: 19 Aug 2020
AbstractforIL-6 −572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study | Full Text | References | PDF (1.8 MB) | EPUB
  • 113 Views
  • 2 CrossRef citations
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Open Access
Article
IKBKB rs2272736 is Associated with Gastric Cancer Survival
Yang Gong, Wenjing Zhao, Qiong Jia, Jiali Dai, Nan Chen, Yuetong Chen, Dongying Gu, Xinying Huo & Jinfei Chen
Pages: 345-352
Published online: 19 Aug 2020
AbstractforIKBKB rs2272736 is Associated with Gastric Cancer Survival | Full Text | References | PDF (1.5 MB) | EPUB
  • 100 Views
  • 3 CrossRef citations
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Open Access

Corrigendum

Correction
Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility [Corrigendum]
Pages: 353-354
Published online: 24 Aug 2020
CitationforVariations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility [Corrigendum] | Full Text | PDF (196.1 KB) | EPUB
  • 83 Views
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Open Access

Original Research

Article
The Relationship Between Single Nucleotide Polymorphisms of SMAD3/SMAD6 and Risk of Esophageal Squamous Cell Carcinoma in Chinese Population
Jinjie Yu, Yunpeng Dong, Weifeng Tang, Huiwen Pan, Lu Lv, Tao Long, Qiang Zhou, Junqing Qi, Jianchao Liu, Guowen Ding, Jun Yin & Lijie Tan
Pages: 355-363
Published online: 17 Nov 2022
AbstractforThe Relationship Between Single Nucleotide Polymorphisms of SMAD3/SMAD6 and Risk of Esophageal Squamous Cell Carcinoma in Chinese Population | Full Text | References | PDF (305.7 KB) | EPUB
  • 95 Views
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Open Access
Article
Prognostic Values of Radiosensitivity Genes and CD19 Status in Gastric Cancer: A Retrospective Study Using TCGA Database
Li-Bo Liang, Xin-Yan Huang, He He & Ji-Yan Liu
Pages: 365-373
Published online: 17 Nov 2022
AbstractforPrognostic Values of Radiosensitivity Genes and CD19 Status in Gastric Cancer: A Retrospective Study Using TCGA Database | Full Text | References | PDF (5.5 MB) | EPUB
  • 108 Views
  • 5 CrossRef citations
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Open Access
Article
Carvedilol Alters Circulating MiR-1 and MiR-214 in Heart Failure
Elham Shirazi-Tehrani, Negar Firouzabadi, Gholamhossein Tamaddon, Ehsan Bahramali & Asma Vafadar
Pages: 375-383
Published online: 03 Sep 2020
AbstractforCarvedilol Alters Circulating MiR-1 and MiR-214 in Heart Failure | Full Text | References | PDF (1.5 MB) | EPUB
  • 169 Views
  • 5 CrossRef citations
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Open Access
Article
Altered Gene Expression in Acne Vulgaris Patients Treated by Oral Isotretinoin: A Preliminary Study
Yuchen Jiang, Haiyan Chen, Le Han, Xiaoyuan Xie, Yue Zheng & Wei Lai
Pages: 385-395
Published online: 15 Sep 2020
AbstractforAltered Gene Expression in Acne Vulgaris Patients Treated by Oral Isotretinoin: A Preliminary Study | Full Text | References | PDF (4.1 MB) | EPUB
  • 261 Views
  • 1 CrossRef citations
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Open Access
Article
A Variant of Leptin Gene Decreases the Risk of Gastric Cancer in Chinese Individuals: Evidence from a Case–Control Study
Renjie Ma & Qi He
Pages: 397-404
Published online: 17 Nov 2022
AbstractforA Variant of Leptin Gene Decreases the Risk of Gastric Cancer in Chinese Individuals: Evidence from a Case–Control Study | Full Text | References | PDF (949.7 KB) | EPUB
  • 97 Views
  • 3 CrossRef citations
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Open Access
Article
Genetic Testing for BCHE Variants Identifies Patients at Risk of Prolonged Neuromuscular Blockade in Response to Succinylcholine
Guang-dan Zhu, Eric Dawson, Angela Huskey, Ronald J Gordon & Andria L Del Tredici
Pages: 405-414
Published online: 17 Nov 2022
AbstractforGenetic Testing for BCHE Variants Identifies Patients at Risk of Prolonged Neuromuscular Blockade in Response to Succinylcholine | Full Text | References | PDF (393.2 KB) | EPUB
  • 261 Views
  • 2 CrossRef citations
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Open Access
Article
Comprehensive Evaluation of Endocytosis-Associated Protein SCAMP3 in Hepatocellular Carcinoma
Ao Zhou, Hongjing Liu & Bin Tang
Pages: 415-426
Published online: 07 Oct 2020
AbstractforComprehensive Evaluation of Endocytosis-Associated Protein SCAMP3 in Hepatocellular Carcinoma | Full Text | References | PDF (5.6 MB) | EPUB
  • 94 Views
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Open Access

Review

Review Article
Genetic Polymorphisms and the Efficacy of Platinum-Based Chemotherapy: Review
Nadiya Nurul Afifah, Ajeng Diantini, Ruri Intania, Rizky Abdulah & Melisa I Barliana
Pages: 427-444
Published online: 17 Nov 2022
AbstractforGenetic Polymorphisms and the Efficacy of Platinum-Based Chemotherapy: Review | Full Text | References | PDF (3.6 MB) | EPUB
  • 192 Views
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Open Access

Original Research

Article
Competing Endogenous RNA (ceRNA) Network Analysis of Autophagy-Related Genes in Hepatocellular Carcinoma
Chenyu Yang, Yixiu Wang, Weijie Xue, Yuwei Xie, Qian Dong & Chengzhan Zhu
Pages: 445-462
Published online: 17 Nov 2022
AbstractforCompeting Endogenous RNA (ceRNA) Network Analysis of Autophagy-Related Genes in Hepatocellular Carcinoma | Full Text | References | PDF (46.3 MB) | EPUB
  • 123 Views
  • 3 CrossRef citations
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Open Access

Review

Review Article
Pharmacogenomics and Pharmacogenetics: In Silico Prediction of Drug Effects in Treatments for Novel Coronavirus SARS-CoV2 Disease
Concetta Cafiero, Agnese Re, Alessandra Micera, Raffaele Palmirotta, Delio Monaco, Francesca Romano, Claudia Fabrizio, Raffaele Di Francia, Andrea Cacciamani, Pier Luigi Surico, Gerardo D’Amato & Salvatore Pisconti
Pages: 463-484
Published online: 17 Nov 2022
AbstractforPharmacogenomics and Pharmacogenetics: In Silico Prediction of Drug Effects in Treatments for Novel Coronavirus SARS-CoV2 Disease | Full Text | References | PDF (2 MB) | EPUB
  • 273 Views
  • 6 CrossRef citations
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Open Access

Corrigendum

Correction
A Variant of Leptin Gene Decreases the Risk of Gastric Cancer in Chinese Individuals: Evidence from a Case–Control Study [Corrigendum]
Page: 485
Published online: 17 Nov 2022
CitationforA Variant of Leptin Gene Decreases the Risk of Gastric Cancer in Chinese Individuals: Evidence from a Case–Control Study [Corrigendum] | Full Text | PDF (166.5 KB) | EPUB
  • 75 Views
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Open Access

Original Research

Article
Identifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula on Alzheimer’s Disease: Coupling Network Pharmacology with GEO Database
Tingting Zhang, Linlin Pan, Yu Cao, Nanyang Liu, Wei Wei & Hao Li
Pages: 487-502
Published online: 17 Nov 2022
AbstractforIdentifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula on Alzheimer’s Disease: Coupling Network Pharmacology with GEO Database | Full Text | References | PDF (15 MB) | EPUB
  • 199 Views
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Open Access
Article
Genetic Association of Epilepsy and Anti-Epileptic Drugs Treatment in Jordanian Patients
Laith N AL-Eitan, Islam M Al-Dalala, Afrah K Elshammari, Wael H Khreisat, Aseel F Nimiri, Adan H Alnaamneh, Hanan A Aljamal & Mansour A Alghamdi
Pages: 503-510
Published online: 16 Oct 2020
AbstractforGenetic Association of Epilepsy and Anti-Epileptic Drugs Treatment in Jordanian Patients | Full Text | References | PDF (311.6 KB) | EPUB
  • 200 Views
  • 3 CrossRef citations
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Open Access
Article
Immune Response-Related Genes – STAT4, IL8RA and CCR7 Polymorphisms in Lung Cancer: A Case–Control Study in China
Yunfan Ma, Yinxi Zhou, Huixin Zhang & Xiaoan Su
Pages: 511-519
Published online: 17 Nov 2022
AbstractforImmune Response-Related Genes – STAT4, IL8RA and CCR7 Polymorphisms in Lung Cancer: A Case–Control Study in China | Full Text | References | PDF (317.1 KB) | EPUB
  • 101 Views
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Open Access
Article
SLCO1B1 and ABCG2 Gene Polymorphisms in a Thai Population
Punyabhorn Rattanacheeworn, Monpat Chamnanphon, Siriwan Thongthip, Wonngarm Kittanamongkolchai, Natavudh Townamchai, Yingyos Avihingsanon, Udomsak Udomnilobol, Thomayant Prueksaritanont, Suree Jianmongkol & Pajaree Chariyavilaskul
Pages: 521-530
Published online: 22 Oct 2020
AbstractforSLCO1B1 and ABCG2 Gene Polymorphisms in a Thai Population | Full Text | References | PDF (2 MB) | EPUB
  • 136 Views
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Open Access

Review

Review Article
Repurposing Drugs for COVID-19: Pharmacokinetics and Pharmacogenomics of Chloroquine and Hydroxychloroquine
Mariana Babayeva & Zvi Loewy
Pages: 531-542
Published online: 23 Oct 2020
AbstractforRepurposing Drugs for COVID-19: Pharmacokinetics and Pharmacogenomics of Chloroquine and Hydroxychloroquine | Full Text | References | PDF (366.8 KB) | EPUB
  • 228 Views
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Original Research

Article
CYP2D6 Predicts Plasma Donepezil Concentrations in a Cohort of Thai Patients with Mild to Moderate Dementia
Monpat Chamnanphon, Sorawit Wainipitapong, Teeravut Wiwattarangkul, Phenphichcha Chuchuen, Kunathip Nissaipan, Weeraya Phaisal, Sookjaroen Tangwongchai, Chonlaphat Sukasem, Supeecha Wittayalertpanya, Andrea Gaedigk, Daruj Aniwattanapong & Pajaree Chariyavilaskul
Pages: 543-551
Published online: 02 Nov 2020
AbstractforCYP2D6 Predicts Plasma Donepezil Concentrations in a Cohort of Thai Patients with Mild to Moderate Dementia | Full Text | References | PDF (2.1 MB) | EPUB
  • 182 Views
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Open Access
Article
Sex-Specific Influence of the SCARB1 Rs5888 SNP on the Serum Lipid Response to Atorvastatin in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Dong-Feng Wu, Dan Lin, Feng Lu, Qin-Chen Liao, Yu-Juan Wu, Zhou Wang, Kun Yu, Wei-Jun Li & Jin-Long Deng
Pages: 553-561
Published online: 29 Oct 2020
AbstractforSex-Specific Influence of the SCARB1 Rs5888 SNP on the Serum Lipid Response to Atorvastatin in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention | Full Text | References | PDF (331.4 KB) | EPUB
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Article
Susceptibility of PON1/PON2 Genetic Variations to Ischemic Stroke Risk in a Chinese Han Population
Yuqin Pan, Bangshun He, Huiling Sun, Tao Xu, Bei Pan, Shukui Wang & Yanping Mei
Pages: 563-570
Published online: 17 Nov 2022
AbstractforSusceptibility of PON1/PON2 Genetic Variations to Ischemic Stroke Risk in a Chinese Han Population | Full Text | References | PDF (296.2 KB) | EPUB
  • 92 Views
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Article
Prevalence of CYP2C8*2 and *3 among Eritreans and its Potential Impact on Artesunate/Amodiaquine Treatment
Lidia Habtemikael, Mulugeta Russom, Iyassu Bahta, Selam Mihreteab, Araia Berhane, Andreas Mårtensson & Jose Pedro Gil
Pages: 571-575
Published online: 12 Nov 2020
AbstractforPrevalence of CYP2C8*2 and *3 among Eritreans and its Potential Impact on Artesunate/Amodiaquine Treatment | Full Text | References | PDF (914.1 KB) | EPUB
  • 134 Views
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Article
Functional Genetic Variation in the 3′-UTRNTRK2 is Associated with Risk of Ischemic Stroke
Jiajia Shi, Ying Sun & Jiajia Hua
Pages: 577-584
Published online: 17 Nov 2022
AbstractforFunctional Genetic Variation in the 3′-UTRNTRK2 is Associated with Risk of Ischemic Stroke | Full Text | References | PDF (1.5 MB) | EPUB
  • 98 Views
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Article
P2RX7 Gene rs1718125 Polymorphism is Related with Postoperative Pain and Fentanyl Intake in Esophageal Cancer Patients
Cuijuan Zheng, Jiayu Wang & Shouxiang Xie
Pages: 585-589
Published online: 17 Nov 2022
AbstractforP2RX7 Gene rs1718125 Polymorphism is Related with Postoperative Pain and Fentanyl Intake in Esophageal Cancer Patients | Full Text | References | PDF (258.7 KB) | EPUB
  • 102 Views
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Article
Association Between Cannabinoid Receptor-1 Gene Polymorphism and the Risk of Diabetic Nephropathy Among Patients with Type 2 Diabetes Mellitus
Xuelian Zhang, Haiqing Zhu, Xiaoyan Xing & Chunyu Zhang
Pages: 591-599
Published online: 12 Nov 2020
AbstractforAssociation Between Cannabinoid Receptor-1 Gene Polymorphism and the Risk of Diabetic Nephropathy Among Patients with Type 2 Diabetes Mellitus | Full Text | References | PDF (415.9 KB) | EPUB
  • 125 Views
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Review

Review Article
Pharmacogenomic Assessment of Patients with Colorectal Cancer and Potential Treatments
Gemma Bruera, Enrico Ricevuto & On behalf of Oncology Network ASL1 Abruzzo
Pages: 601-617
Published online: 16 Nov 2020
AbstractforPharmacogenomic Assessment of Patients with Colorectal Cancer and Potential Treatments | Full Text | References | PDF (398.6 KB) | EPUB
  • 239 Views
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Original Research

Article
Influence of PSRC1, CELSR2, and SORT1 Gene Polymorphisms on the Variability of Warfarin Dosage and Susceptibility to Cardiovascular Disease
Laith N AL-Eitan, Barakat Z Elsaqa, Ayah Y Almasri, Hatem A Aman, Rame H Khasawneh & Mansour A Alghamdi
Pages: 619-632
Published online: 17 Nov 2020
AbstractforInfluence of PSRC1, CELSR2, and SORT1 Gene Polymorphisms on the Variability of Warfarin Dosage and Susceptibility to Cardiovascular Disease | Full Text | References | PDF (1.4 MB) | EPUB
  • 166 Views
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Article
The Relationship Between Human Papillomavirus, OFD1 and Primary Ciliogenesis in the Progression of Oropharyngeal Cancer: A Retrospective Cohort Study
Hong-xue Meng, Xin-xin Yang, Rui-qi Liu, Jun-jie Bao, Yun-jing Hou, Ji Sun, Su-sheng Miao & Guo-fan Qu
Pages: 633-644
Published online: 17 Nov 2022
AbstractforThe Relationship Between Human Papillomavirus, OFD1 and Primary Ciliogenesis in the Progression of Oropharyngeal Cancer: A Retrospective Cohort Study | Full Text | References | PDF (2.6 MB) | EPUB
  • 110 Views
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Article
Should CYP2C19 Genotyping Be Recommended as a Straight Forward Approach to Optimize Clopidogrel Utilization in Patients with Ischemic Stroke Complicated by Type 2 Diabetes Mellitus?
Jialin Sun, Ping Leng, Chen Sun, Wen Xu, Zhenhuan Zhao, Xiao Li, Xiaolei Zhang & Jing Li
Pages: 645-653
Published online: 23 Nov 2020
AbstractforShould CYP2C19 Genotyping Be Recommended as a Straight Forward Approach to Optimize Clopidogrel Utilization in Patients with Ischemic Stroke Complicated by Type 2 Diabetes Mellitus? | Full Text | References | PDF (1.2 MB) | EPUB
  • 107 Views
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Article
Impact of APOE Alleles-by-Diet Interactions on Glycemic and Lipid Features– A Cross-Sectional Study of a Cohort of Type 2 Diabetes Patients from Western Mexico: Implications for Personalized Medicine
Rafael Torres-Valadez, Omar Ramos-Lopez, Kevin J Frías Delgadillo, Aurelio Flores-García, Esaú Rojas Carrillo, Pedro Aguiar-García, J Antonio Bernal Pérez, Erika Martinez-Lopez, J Alfredo Martínez & Eloy A Zepeda-Carrillo
Pages: 655-663
Published online: 26 Nov 2020
AbstractforImpact of APOE Alleles-by-Diet Interactions on Glycemic and Lipid Features– A Cross-Sectional Study of a Cohort of Type 2 Diabetes Patients from Western Mexico: Implications for Personalized Medicine | Full Text | References | PDF (1 MB) | EPUB
  • 224 Views
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Case Report

Case Report
The Identification of a Novel Thiopurine S-Methyltransferase Allele, TPMT*45, in Korean Patient with Crohn’s Disease
Changhee Ha, Eun Sil Kim, Yiyoung Kwon, Yon Ho Choe, Mi Jin Kim & Soo-Youn Lee
Pages: 665-671
Published online: 26 Nov 2020
AbstractforThe Identification of a Novel Thiopurine S-Methyltransferase Allele, TPMT*45, in Korean Patient with Crohn’s Disease | Full Text | References | PDF (1.3 MB) | EPUB
  • 100 Views
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Original Research

Article
Association of MDM4 Gene rs4245739 Polymorphism with the Risk and Clinical Characteristics of Colorectal Cancer in a Chinese Han Population
De-Ming Zhao, Yu-E Diao & Qing Xu
Pages: 673-678
Published online: 26 Nov 2020
AbstractforAssociation of MDM4 Gene rs4245739 Polymorphism with the Risk and Clinical Characteristics of Colorectal Cancer in a Chinese Han Population | Full Text | References | PDF (536.1 KB) | EPUB
  • 91 Views
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Article
Cystic Fibrosis Polymorphic Variants in a Russian Population
Anna Kiseleva, Marina Klimushina, Evgeniia Sotnikova, Olga Skirko, Mikhail Divashuk, Olga Kurilova, Alexandra Ershova, Eleonora Khlebus, Anastasia Zharikova, Irina Efimova, Maria Pokrovskaya, Petr A Slominsky, Svetlana Shalnova, Alexey Meshkov & Oxana Drapkina
Pages: 679-686
Published online: 01 Dec 2020
AbstractforCystic Fibrosis Polymorphic Variants in a Russian Population | Full Text | References | PDF (2.4 MB) | EPUB
  • 150 Views
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Review

Review Article
Identification of Novel Biomarkers for Predicting Kidney Injury Due to Drugs Using “Omic” Strategies
Linda Awdishu, Amandla Atilano-Roque, Stacey Tuey & Melanie S Joy
Pages: 687-705
Published online: 17 Nov 2022
AbstractforIdentification of Novel Biomarkers for Predicting Kidney Injury Due to Drugs Using “Omic” Strategies | Full Text | References | PDF (2.8 MB) | EPUB
  • 180 Views
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Original Research

Article
A Seven-NF-κB-Related Gene Signature May Distinguish Patients with Ulcerative Colitis-Associated Colorectal Carcinoma
Chao-Yi Ge, Li-Yuan Wei, Yu Tian & Hua-Hong Wang
Pages: 707-718
Published online: 02 Dec 2020
AbstractforA Seven-NF-κB-Related Gene Signature May Distinguish Patients with Ulcerative Colitis-Associated Colorectal Carcinoma | Full Text | References | PDF (8.4 MB) | EPUB
  • 115 Views
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Short Report

Brief Report
Pharmacist Consult Reports to Support Pharmacogenomics Report Interpretation
David Bright, Claire Saadeh, Susan DeVuyst-Miller, Minji Sohn, Ashley Choker & Anna Langerveld
Pages: 719-724
Published online: 17 Nov 2022
AbstractforPharmacist Consult Reports to Support Pharmacogenomics Report Interpretation | Full Text | References | PDF (340.7 KB) | EPUB
  • 126 Views
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Original Research

Article
Association of IL-17 and IL-23 Gene Variants with Plasma Levels and Risk of Vulvovaginal Candidiasis in a Chinese Han Population
Wei Li, Wenyin Shi, Yujun Yin, Juan Chen & Lanlan Luo
Pages: 725-733
Published online: 17 Nov 2022
AbstractforAssociation of IL-17 and IL-23 Gene Variants with Plasma Levels and Risk of Vulvovaginal Candidiasis in a Chinese Han Population | Full Text | References | PDF (606.8 KB) | EPUB
  • 142 Views
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Article
A Novel Prognostic Score Based on ZG16 for Predicting CRC Survival
Wei Wang, Jian-Fang Sun, Xiao-Zhong Wang, Hou-Qun Ying, Xia-Hong You & Fan Sun
Pages: 735-747
Published online: 16 Dec 2020
AbstractforA Novel Prognostic Score Based on ZG16 for Predicting CRC Survival | Full Text | References | PDF (5.7 MB) | EPUB
  • 121 Views
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Article
Case–Control Study on TNFRSF6B Gene Polymorphism and Susceptibility to Gastric Cancer in a Chinese Han Population
Xuyu Gu, Zhenwei Mao, Huiwen Pan, Chen Zou, Guowen Ding & Yu Fan
Pages: 749-756
Published online: 17 Nov 2022
AbstractforCase–Control Study on TNFRSF6B Gene Polymorphism and Susceptibility to Gastric Cancer in a Chinese Han Population | Full Text | References | PDF (298.1 KB) | EPUB
  • 94 Views
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Article
Screening and Identifying Cisplatin-Related Gene Mutations in Lung Squamous Cell Carcinoma
Xiaohua Li, Yuntao Wang, Sheng Hu & Yifeng Bai
Pages: 757-766
Published online: 18 Dec 2020
AbstractforScreening and Identifying Cisplatin-Related Gene Mutations in Lung Squamous Cell Carcinoma | Full Text | References | PDF (6.6 MB) | EPUB
  • 100 Views
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Article
Single-Nucleotide Polymorphisms in Genes Predisposing to Leprosy in Leprosy Household Contacts in Zhejiang Province, China
Yun-Liang Shen, Si-Yu Long, Wen-Ming Kong, Li-Mei Wu, Li-Juan Fei, Qiang Yao & Hong-Sheng Wang
Pages: 767-773
Published online: 17 Nov 2022
AbstractforSingle-Nucleotide Polymorphisms in Genes Predisposing to Leprosy in Leprosy Household Contacts in Zhejiang Province, China | Full Text | References | PDF (954.6 KB) | EPUB
  • 122 Views
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