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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 3
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Research Article

Intestinal and hepatic first-pass extraction of the 11β-HSD1 inhibitor AMG 221 in rats with chronic vascular catheters

Qiuxia GaoDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSA
,
Robert E. KimuraDepartment of Pediatrics, Rush University Medical Center Chicago, ILUSA
,
Xiping ZhangDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSA
,
Joon NamDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSA
,
Benny M. AmoreDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSA
,
Dean HickmanDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSA
,
J. Greg SlatterDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSA
&
Maurice G. EmeryDepartment of Pharmacokinetics and Drug Metabolism, Amgen Inc. Seattle, WAUSACorrespondence[email protected]
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Pages 264-269 | Received 05 Dec 2011, Accepted 18 Jan 2013, Published online: 21 Mar 2013

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