Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study

R. A. BudinskyThe Dow Chemical Company Midland, MIUSACorrespondence[email protected]

D. SchrenkDepartment of Food Chemistry and Environmental Toxicology, Technical University of Kaiserslautern KaiserslauternGermany

T. SimonTed Simon, LLC Winston, GAUSA

M. Van den BergInstitute for Risk Assessment Sciences, Utrecht University Utrechtthe Netherlands

J. F. ReichardToxicology Excellence for Risk Assessment Cincinnati, OHUSA

J. B. SilkworthGlobal Research Center, General Electric Company NiskayunaNew York

L. L. AylwardSummit Toxicology LLP, Falls Church, VAUSA

A. BrixExperimental Pathology Laboratories, Inc Research Triangle Park, NCUSA

T. GasiewiczSchool of Medicine and Dentistry, University of Rochester Rochester, NYUSA

N. KaminskiCenter for Integrative Toxicology, Michigan State University East Lansing, MIUSA

G. PerdewVeternary and Biomedical Sciences, The Pennsylvania State University, University Park PAUSA

T. B. StarrTBS Associates Raleigh, NCUSA

N. J. WalkerNational Institute of Environmental Health Sciences, Research Triangle Park NCUSA

J. C. RowlandsThe Dow Chemical Company Midland, MIUSA

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