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mAbs Volume 3, 2011 - Issue 5
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The improvement of an anti-CD22 immunotoxin

Conversion to single-chain and disulfide stabilized form and affinity maturation by alanine scan

Seiji Kawa Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Bethesda, MD USA
,
Masanori Onda Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Bethesda, MD USA
,
Mitchell Ho Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Bethesda, MD USA
,
Robert J. Kreitman Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Bethesda, MD USA
,
Tapan K. Bera Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Bethesda, MD USA
&
Ira Pastan Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Bethesda, MD USACorrespondence[email protected]
Pages 479-486 | Received 23 Jun 2011, Accepted 28 Jul 2011, Published online: 01 Sep 2011

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