mAbs, Volume 3, Issue 5 (2011)

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mAbs, Volume 3, Issue 5 (2011)

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Editorial

Editorial
Therapeutic Fc-fusion proteins and peptides as successful alternatives to antibodies
Alain Beck & Janice M. Reichert
Pages: 415-416
Published online: 01 Sep 2011
AbstractforTherapeutic Fc-fusion proteins and peptides as successful alternatives to antibodies | Full Text | PDF (479.8 KB)
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Meeting Report

Meeting Report
2nd Charles Richet et Jules Héricourt Workshop
Therapeutic antibodies and anaphylaxis; May 31-June 1, 2011, Tours, France
Arnaud Daguet & Hervé Watier
Pages: 417-421
Published online: 01 Sep 2011
Abstractfor2nd Charles Richet et Jules Héricourt Workshop | Full Text | References | PDF (1 MB)
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Review

Review Article
Neonatal Fc receptor and IgG-based therapeutics
Timothy T. Kuo & Victoria G. Aveson
Pages: 422-430
Published online: 01 Sep 2011
AbstractforNeonatal Fc receptor and IgG-based therapeutics | Full Text | References | PDF (2.2 MB)
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Review Article
Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies
Imre Kacskovics, Judit Cervenak, Anna Erdei, Richard A. Goldsby & John E. Butler
Pages: 431-439
Published online: 01 Sep 2011
AbstractforRecent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies | Full Text | References | PDF (2.1 MB)
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Review Article
Bridging the gap
Facilities and technologies for development of early stage therapeutic mAb candidates
Trent P. Munro, Stephen M. Mahler, Edwin P. Huang, David Y. Chin & Peter P. Gray
Pages: 440-452
Published online: 01 Sep 2011
AbstractforBridging the gap | Full Text | References | PDF (2.6 MB)
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Review Article
Biochemical and biophysical characterization of humanized IgG1 produced in Pichia pastoris
Sha Ha, Yang Wang & Richard R. Rustandi
Pages: 453-460
Published online: 01 Sep 2011
AbstractforBiochemical and biophysical characterization of humanized IgG1 produced in Pichia pastoris | Full Text | References | PDF (2 MB)
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Review Article
Infections associated with monoclonal antibody and fusion protein therapy in humans
Florence Uettwiller, Emilie Rigal & Cyrille Hoarau
Pages: 461-466
Published online: 01 Sep 2011
AbstractforInfections associated with monoclonal antibody and fusion protein therapy in humans | Full Text | References | PDF (1.5 MB)
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Review Article
Utilization of monoclonal antibody-targeted nanomaterials in the treatment of cancer
Daniel C. Julien, Steven Behnke, Guankui Wang, Gordon K. Murdoch & Rodney A. Hill
Pages: 467-478
Published online: 01 Sep 2011
AbstractforUtilization of monoclonal antibody-targeted nanomaterials in the treatment of cancer | Full Text | References | PDF (3.3 MB)
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Report

Article
The improvement of an anti-CD22 immunotoxin
Conversion to single-chain and disulfide stabilized form and affinity maturation by alanine scan
Seiji Kawa, Masanori Onda, Mitchell Ho, Robert J. Kreitman, Tapan K. Bera & Ira Pastan
Pages: 479-486
Published online: 01 Sep 2011
AbstractforThe improvement of an anti-CD22 immunotoxin | Full Text | References | PDF (2.9 MB)
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Article
Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design
Enrico L. DiGiammarino, John E. Harlan, Karl A. Walter, Uri S. Ladror, Rohinton P. Edalji, Charles W. Hutchins, Marc R. Lake, Amy J. Greischar, Junjian Liu, Tariq Ghayur & Clarissa G. Jakob
Pages: 487-494
Published online: 01 Sep 2011
AbstractforLigand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design | Full Text | References | PDF (2.1 MB) | Supplemental
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Brief Report

Brief Report
Bacterial expression and characterization of a novel human anti-IgE scFv fragment
MingRong Wang, YongXia Zhang, TianFei Du, YunJian Dai, YongZhi He, Xin Yu, Cong Cong & MingYue He
Pages: 495-499
Published online: 01 Sep 2011
AbstractforBacterial expression and characterization of a novel human anti-IgE scFv fragment | Full Text | References | PDF (1.6 MB)
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Editor's Corner

Editorial
2011 upcoming meetings
Janice M. Reichert
Pages: 500-501
Published online: 01 Sep 2011
Citationfor2011 upcoming meetings | PDF (501.1 KB)
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