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OncoImmunology Volume 1, 2012 - Issue 9
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Original Research

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Richard Metz New Link Genetics Corporation; Ames, IA USA
,
Sonja Rust New Link Genetics Corporation; Ames, IA USA
,
James B. DuHadaway Lankenau Institute for Medical Research; Wynnewood, PA USA
,
Mario R. Mautino New Link Genetics Corporation; Ames, IA USA
,
David H. Munn Immunotherapy Center; Georgia Health Sciences University; Augusta, GA USA
,
Nicholas N. Vahanian New Link Genetics Corporation; Ames, IA USA
,
Charles J. Link New Link Genetics Corporation; Ames, IA USA
&
George C. Prendergast Lankenau Institute for Medical Research; Wynnewood, PA USA; Kimmel Cancer Center; Thomas Jefferson University; Philadelphia, PA USACorrespondence[email protected]
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Pages 1460-1468 | Received 29 Jul 2012, Accepted 03 Aug 2012, Published online: 06 Dec 2012

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