References
- BENET, L. Z. and ZIA-ÄMIRHOSSEINI, P., 1995, Basic principles of pharmacokinetics. Toxicologic Pathology, 23, 115–123.
- CARLILE, D. J., HAKOOZ, N., BAYLISS, M. K. and HOUSTON, J. B., 1999, Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans. British Journal of Clinical Pharmacology, 47, 625–635.
- CLARKE, S. E., BALDWIN, S. J., BLOOMER, J. C., AYRTON, A. D., Sozio, R. S. and CHENERY, R. J., 1994, Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes. Chemical Research in Toxicology, 7, 836–842.
- CRESPI, C. L., MILLER, V. P. and PENMAN, B. W., 1997, Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450. Analytical Biochemistry, 248, 188–190.
- HOUSTON, J. B. and CARLILE, D. J., 1997, Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices. Drug Metabolism Reviews, 29, 891–922.
- HOUSTON, J. B. and KENWORTHY, K. E., 2000, In vitro—in vivo scaling of CYP kinetic data not consistent with the classical Michaelis—Menten model. Drug Metabolism and Disposition, 28, 246–254.
- LIPINSKI, C. A., LOMBARDO, F., DOMINY, B. W. and FEENEY, P. J., 1997, Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced Drug Delivery Reviews, 23, 3–25.
- OBACIT, R. S., 1999, Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: an examination of in vitro half-life approach and nonspecific binding to microsomes. Drug Metabolism and Disposition, 27, 1350–1359.
- RODRIGUES, A. D., 1997, Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective. Pharmaceutical Research, 14, 1504–1510.
- SCHNEIDER, G., COASSOLO, P. and LAVE, T., 1999, Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques. Journal of Medicinal Chemistry, 42, 5072–5076.
- WILKINSON, G. R. and SHAND, G. G., 1975, A physiological approach to hepatic drug clearance. Clinical Pharmacology and Therapeutics, 18, 377–390.