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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 2
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Animal Pharmacokinetics and metabolism

Effects of triptolide on pharmacokinetics of fenofibrate in rats and its potential mechanism

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Pages 211-215 | Received 27 Dec 2017, Accepted 05 Feb 2018, Published online: 06 Mar 2018

References

  • Agouridis AP, Kostapanos MS, Tsimihodimos V, et al. (2012). Effect of rosuvastatin monotherapy or in combination with fenofibrate or omega-3 fatty acids on lipoprotein subfraction profile in patients with mixed dyslipidaemia and metabolic syndrome. Int J Clin Pract 66:843–53.
  • Brinker AM, Raskin I. (2005). Determination of triptolide in root extracts of Tripterygium wilfordii by solid-phase extraction and reverse-phase high-performance liquid chromatography. J Chromatogr A 1070:65–70.
  • Chapman MJ. (1987). Pharmacology of fenofibrate. Am J Med 83:21–5.
  • Filippatos TD. (2012). A review of time courses and predictors of lipid changes with fenofibric acid-statin combination. Cardiovasc Drugs Ther 26:245–55.
  • Genest Jr J, Nguyen NH, Theroux P, et al. (2000). Effect of micronized fenofibrate on plasma lipoprotein levels and hemostatic parameters of hypertriglyceridemic patients with low levels of high-density lipoprotein cholesterol in the fed and fasted state. J Cardiovasc Pharmacol 35:164–72.
  • Hamilton SJ, Chew GT, Davis TM, Watts GF. (2010). Fenofibrate improves endothelial function in the brachial artery and forearm resistance arterioles of statin-treated Type 2 diabetic patients. Clin Sci (Lond) 118:607–15.
  • Hu L, Wu H, Niu F, et al. (2011). Design of fenofibrate microemulsion for improved bioavailability. Int J Pharm 420:251–5.
  • Huang Y, Zhao J, Jian W, Wang G. (2017). Effects of verapamil on the pharmacokinetics of dihydromyricetin in rats and its potential mechanism. Xenobiotica. [Epub ahead of print]. DOI:10.1080/00498254.2017.1366576
  • Jia Y, Liu J, Xu J. (2017). Influence of grapefruit juice on pharmacokinetics of triptolide in rats grapefruit juice on the effects of triptolide. Xenobiotica 48:407–11.
  • Li H, Liu L, Xie L, et al. (2016). Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharm Biol 54:2886–94.
  • Li W, Liu Y, He YQ, et al. (2008). Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes. Xenobiotica 38:1551–65.
  • Mao SJ, Huang XM. (2016). Tripterygium wilfordii Hook F is efficacious in the treatment of Henoch-Schonlein purpura nephritis in children. World J Pediatr 12:375–6.
  • Miller DB, Spence JD. (1998). Clinical pharmacokinetics of fibric acid derivatives (fibrates). Clin Pharmacokinet 34:155–62.
  • Moutzouri E, Kei A, Elisaf MS, Milionis HJ. (2010). Management of dyslipidemias with fibrates, alone and in combination with statins: role of delayed-release fenofibric acid. Vasc Health Risk Manag 6:525–39.
  • Najib J. (2002). Fenofibrate in the treatment of dyslipidemia: a review of the data as they relate to the new suprabioavailable tablet formulation. Clin Ther 24:2022–50.
  • Park JS, Rehman SU, Kim IS, et al. (2017). Evaluation of herb-drug interactions of hovenia dulcis fruit extracts. Pharmacogn Mag 13:236–9.
  • Wang BY, Cao J, Chen JW, Liu QY. (2014a). Triptolide induces apoptosis of gastric cancer cells via inhibiting the overexpression of MDM2. Med Oncol 31:270.
  • Wang Q, Meng J, Dong A, et al. (2016). The pharmacological effects and mechanism of tripterygium wilfordii Hook F in central nervous system autoimmunity. J Altern Complement Med 22:496–502.
  • Wang X, Zhang X, Liu F, et al. (2017). The effects of triptolide on the pharmacokinetics of sorafenib in rats and its potential mechanism. Pharm Biol 55:1863–7.
  • Wang XF, Zhao YB, Wu Q, et al. (2014b). Triptolide induces apoptosis in endometrial cancer via a p53independent mitochondrial pathway. Mol Med Rep 9:39–44.
  • Zhang H, Ya G, Rui H. (2017). Inhibitory Effects of triptolide on human liver cytochrome P450 enzymes and P-glycoprotein. Eur J Drug Metab Pharmacokinet 42:89–98.
  • Zhao Y, Yu J, Liu J, An X. (2016). The role of liuwei dihuang pills and ginkgo leaf tablets in treating diabetic complications. Evid Based Complement Alternat Med 2016:7931314.

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