Evaluation of pharmacokinetic interactions between bicyclol and co-administered drugs in rat and human liver microsomes in vitro and in rats in vivo

References

• Amundsen R, Åsberg A, Ohm IK, Christensen H. (2012). Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro. Drug Metab Dispos 40:655–61.
   PubMed Web of Science ®Google Scholar
• Bhavesh D, Shah S, Shivprakash. (2009). Determination of fenofibric acid in human plasma by ultra performance liquid chromatography-electrospray ionization mass spectrometry: application to a bioequivalence study. Biomed Chromatogr 23:922–28.
   PubMed Web of Science ®Google Scholar
• Chiba K. (1995). Drug-drug interaction via metabolism by cytochrome P450. Farumashia 31:992–96.
   Google Scholar
• Choi JS, Choi I, Choi DH. (2016). Effects of pioglitazone on the pharmacokinetics of nifedipine and its main metabolite, dehydronifedipine, in rats. Eur J Drug Metab Pharmacokinet 41:231–38.
   PubMed Web of Science ®Google Scholar
• Choi YH, Lee MG. (2006). Effects of enzyme inducers and inhibitors on the pharmacokinetics of metformin in rats: involvement of CYP2C11, 2D1 and 3A1/2 for the metabolism of metformin. Br J Pharmacol 149:424–30.
   PubMed Web of Science ®Google Scholar
• Choi YH, Lee MG. (2012). Pharmacokinetic and pharmacodynamic interaction between nifedipine and metformin in rats: competitive inhibition for metabolism of nifedipine and metforminby each other via CYP isozymes. Xenobiotica 42:483–95.
   PubMed Web of Science ®Google Scholar
• Dai Y, Hebert MF, Isoherranen N, et al. (2006). Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro. Drug Metab Dispos 34:836–47.
   PubMed Web of Science ®Google Scholar
• Han Y, Shi JP, Ma AL, et al. (2014). Randomized, vitamin E-controlled trial of bicyclol plus metformin in non-alcoholic fatty liver disease patients with impaired fasting glucose. Clin Drug Investig 34:1–7.
   PubMed Web of Science ®Google Scholar
• Hermann M, Christensen H, Reubsaet JL. (2005). Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LC-tandem MS. Anal Bioanal Chem 382:1242–9.
   PubMed Web of Science ®Google Scholar
• Jaakkola T, Laitila J, Neuvonen PJ, Backman JT. (2006). Pioglitazone is metabolised by CYP2C8 and CYP3A4 in vitro: potential for interactions with CYP2C8 inhibitors. Basic Clin Pharmacol Toxicol 99:44–51.
   PubMed Web of Science ®Google Scholar
• Ju MH, Li Y. (2005). Metabolism of bicyclol in rat and human liver microsomes in vitro. Acta Pharmaceutica Sinica 2:111–6.
   Google Scholar
• Kajosaari LI, Laitila J, Neuvonen PJ, Backman JT. (2005). Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin. Basic Clin Pharmacol Toxicol 97:249–56.
   PubMed Web of Science ®Google Scholar
• Kelly PA, Wang H, Napoli KL, et al. (1999). Metabolism of cyclosporine by cytochromes P450 3A9 and 3A4. Eur J Drug Metab Pharmacokinet 24:321–8.
   PubMed Web of Science ®Google Scholar
• Krieter PA, Colletti AE, Doss GA, Miller RR. (1994) Disposition and metabolism of the hypoglycemic agent pioglitazone in rats. Drug Metab Dispos 22:625–30.
   PubMed Web of Science ®Google Scholar
• Lamoureux F, Picard N, Boussera B, et al. (2012). Sirolimus and everolimus intestinal absorption and interaction with calcineurin inhibitors: a differential effect between cyclosporine and tacrolimus. Fundam Clin Pharmacol 26:463–72.
   PubMed Web of Science ®Google Scholar
• Li Y, Li Y, Liu GT. (2004). Protective effects of bicyclol on liver fibrosis induced by carbon tetrachloride. Chin Med J, 84:2096–101.
   Google Scholar
• Liu GT. (2009). Bicyclol: a novel drug for treating chronic viral hepatitis B and C. Med Chem 5:29–43.
   PubMed Web of Science ®Google Scholar
• Martignoni M, Groothuis GM, de Kanter R. (2006). Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin Drug Metab Toxicol 2:875–94.
   PubMed Web of Science ®Google Scholar
• Mc Donnell CG, Shorten G, Van Pelt FN. (2005). Effect of atorvastatin and fluvastatin on the metabolism of midazolam by cytochrome P450 in vitro. Anaesthesia 60:747–53.
   PubMed Web of Science ®Google Scholar
• Miller DB, Spence JD. (1998). Clinical pharmacokinetics of fibric acid derivatives (fibrates). Clin Pharmacokinet 34:155–62.
   PubMed Web of Science ®Google Scholar
• Müller J, Keiser M, Drozdzik M, Oswald S. (2017). Expression, regulation and function of intestinal drug transporters: an update. Biol Chem 398:175–92.
   PubMed Web of Science ®Google Scholar
• Niwa T, Yamamoto S, Saito M, et al. (2007). Effect of cyclosporine and tacrolimus on cytochrome p450 activities in human liver microsomes. Yakugaku Zasshi 127:209–16.
   PubMed Web of Science ®Google Scholar
• Omura T, Sato R. (1964). The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239:2370–78.
   PubMed Web of Science ®Google Scholar
• Park JE, Kim KB, Bae SK, et al. (2008). Contribution of cytochrome P450 3A4 and 3A5 to the metabolism of atorvastatin. Xenobiotica 38:1240–51.
   PubMed Web of Science ®Google Scholar
• Sahi J, Black CB, Hamilton GA, et al. (2003). Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition. Drug Metab Dispos 31:439–46.
   PubMed Web of Science ®Google Scholar
• Scheen AJ. (1996). Clinical pharmacokinetics of metformin. Clin Pharmacokinet 30:359–71.
   PubMed Web of Science ®Google Scholar
• Tan W, Chen H, Zhao J, et al. (2008). A study of intestinal absorption of bicyclol in rats: active efflux transport and metabolism as causes of its poor bioavailability. J Pharm Pharm Sci 11:97–105.
   PubMed Web of Science ®Google Scholar
• Venkataramanan R, Zang S, Gayowski T, Singh N. (2002). Voriconazole inhibition of the metabolism of tacrolimus in a liver transplant recipient and in human liver microsomes. Antimicrob Agents Chemother 46:3091–3.
   PubMed Web of Science ®Google Scholar
• Vickers AE, Fischer V, Connors S, et al. (1992). Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines. Drug Metab Dispos 20:802–9.
   PubMed Web of Science ®Google Scholar
• Wang H, Li Y. (2006). Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice. Eur J Pharmacol 534:194–201.
   PubMed Web of Science ®Google Scholar
• Xie F, Ding X, Zhang QY. (2016). An update on the role of intestinal cytochrome P450 enzymes in drug disposition. Acta Pharm Sin B 6:374–83.
   PubMed Web of Science ®Google Scholar
• Yao XM, Wang BL, Yu HY, Li Y. (2011). Effect of bicyclol on the activity and expression of cytochrome P450 after hepatic warm ischemia/reperfusion in rats. J Asian Nat Prod Res 13:634–44.
   Web of Science ®Google Scholar
• Zhu PL, Pan SY, Zhou SF, et al. (2015). Effects of combined dietary supplementation with fenofibrate and Schisandrae Fructus pulp on lipid and glucose levels and liver function in normal and hypercholesterolemic mice. Drug Design Develop Ther 9:923–35.
   PubMed Web of Science ®Google Scholar