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the fate of foreign compounds in biological systems
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Preface for Special Issue: “Emerging strategies, technologies and approaches for the next generation ADCs”

Editors M Wallesa Pharmacokinetic Sciences, Biomedical Research, Novartis, Basel, SwitzerlandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8376-8311View further author information
ORCID Icon &
K Xub BioAnalytical Sciences, Genentech Inc., South San Francisco, CA, USAView further author information
Received 26 Jul 2024, Accepted 26 Jul 2024, Accepted author version posted online: 29 Jul 2024
Accepted author version

References:

  • Gray ME, Zielinski KM, Xu F, Elder KK, McKay SJ, Ojo VT, Benjamin SR, Yaseen AA, Brooks TA, Tumey LN. 2024. A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin cleavable ADC linkers. Xenobiotica. May 13:1-13. doi: 10.1080/00498254.2024.2352051..
  • Hengel S, Erickson A, Hossam K, Alley, S. 2024. A modeling approach to compare ADC deconjugation and systemic elimination rates of individual drug-load species using native ADC LC-MS data from human plasma. Xenobiotica.
  • Huang Q, Pilvankar MR, Dixit R, Yu H.2 024. Approaches to Improve the Translation of Safety, Pharmacokinetics and Therapeutic Index of ADCs. Xenobiotica. May 11:1-16. doi: 10.1080/00498254.2024.2352600..
  • Liao MZ, Leipold DD, Chen SC, Li Z, Kamath AV, Li C. 2024.Wy Translational PK/PD framework for antibody-drug conjugates to inform drug discovery and development. Xenobiotica. May 13:1-11. doi: 10.1080/00498254.2024.2351044..
  • Marelli M, Moore E, Rice M, Roy G, Zhang W. 2024. Emerging conjugation strategies and protein engineering technologies aim to improve ADCs in the fight against cancer. Xenobiotica.
  • Murphy A, Hill R, Berna M. 2024. Bioanalytical approaches to support the development of antibody-oligonucleotide conjugate (AOC) therapeutic proteins. Xenobiotica. Apr 12:1-23. doi: 10.1080/00498254.2024.2339983..
  • Park SJ, Lim JH, Lee J, Lee J, Hwang S, Kim H, Jo S, Shin D, Ma SH, Kim ML, Shin YG. 2024. Investigation of pharmacokinetic properties of a PEGylated bilirubin nanoparticle in male Sprague-Dawley rats using liquid chromatography-quadrupole time-of-flight mass spectrometry. Xenobiotica. Nov 16:1-36. doi: 10.1080/00498254.2023.2284859..
  • Rudolph B, Davis JA, Hainzl D, Walles M. 2024. A general perspective for the conduct of radiolabelled distribution, metabolism, and excretion studies for antibody-drug conjugates. Xenobiotica.
  • Sun H, Wienkers LC, Lee A. 2024. Beyond Cytotoxic Potency: Disposition Features Required to Design ADC Payload. Xenobiotica. Jul 17:1-25. doi: 10.1080/00498254.2024.2381139..
  • Yip V, Saad OM, Leipold DL, Li C, Kamath A, Shen BQ. 2024. Monomethyl Auristatin E (MMAE), a Payload for Multiple Antibody Drug Conjugates (ADCs), Demonstrates Differential Red Blood Cell Partitioning Across Human and Animal Species. Xenobiotica. Apr 22:1-13. doi: 10.1080/00498254.2024.2345849..

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