References
- American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5). 5th. Washington, DC: American Psychiatric Association;2013. p. 490–97
- American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-IV). 4th. Washington, DC: American Psychiatric Association;1994. p. 194–204
- World Health Organization. The ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. Geneva: World Health Organization; 1993. p. 70–83.
- World Health Organization. Global status report on alcohol and health 2018. Geneva: World Health Organization; 2018.
- Rosen AD, Robertson KD, Hlady RA, Muench C, Lee J, Philibert R, Horvath S, Kaminsky ZA, Lohoff FW. DNA methylation age is accelerated in alcohol dependence. Transl Psychiatry. 2018;5:182. doi:https://doi.org/10.1038/s41398-018-0233-4.
- Degenhardt L, Bharat C, Bruno R, Glantz MD, Sampson NA, Lago L, Aguilar-Gaxiola S, Alonso J, Andrade LH, Bunting B, et al. Concordance between the diagnostic guidelines for alcohol and cannabis use disorders in the draft ICD-11 and other classification systems: analysis of data from the WHO’s World Mental Health Surveys. Addiction. 2019;114:534–52.
- Ji AL, Lou PA, Dong ZM, Xu CR, Zhang P, Chang GQ, Li T. The prevalence of alcohol dependence and its association with hypertension: a population-based cross-sectional study4 in Xuzhou city, China. BMC Public Health. 2018;18:364. doi:https://doi.org/10.1186/s12889-018-5276-1.
- Zhu JJ, Wang YJ, Wang HB, Cheng WW, Li ZP, Qian YF, Li XH, Li XS, Yu YQ. Abnormal gray matter asymmetry in alcohol dependence. Neuroreport. 2018;29:753–59. doi:https://doi.org/10.1097/WNR.0000000000001027.
- Thayer RE, Hagerty SL, Sabbineni A, Claus ED, Hutchison KE, Weiland BJ. Negative and interactive effects of sex, aging, and alcohol abuse on gray matter morphometry. Hum Brain Mapp. 2016;37:2276–92. doi:https://doi.org/10.1002/hbm.23172.
- Sorg SF, Squeglia LM, Taylor MJ, Alhassoon OM, Delano-Wood LM, Igor Grant I. Effects of aging on frontal white matter microstructure in alcohol use disorder and associations with processing speed. J Stud Alcohol Drugs. 2015;76:296–306. doi:https://doi.org/10.15288/jsad.2015.76.296.
- Venkataraman A, Kalk N, Sewell G, Ritchie CW, Anne Lingford-Hughes A. Alcohol and Alzheimer’s disease-does alcohol dependence contribute to beta-amyloid deposition, neuroinflammation and neurodegeneration in Alzheimer’s Disease? Alcohol. 2017;52:158.
- Sachdeva A, Chandra M, Choudhary M, Dayal P, Anand KS, Dementia A-R. Neurocognitive impairment: a review study. Int J High Risk Behav Addict. 2016;5:e27976. doi:https://doi.org/10.5812/ijhrba.27976.
- Anderson P, Moller L, Galea G. Alcohol in the European Union: consumption, harm and policy approaches. Copenhagen: World Health Organization Regional Office for Europe; 2012.
- Cheng HG, Deng F, Xiong W, Phillips MR. Prevalence of alcohol use disorders in mainland China: a systematic review. Addiction. 2015;110:761–74. doi:https://doi.org/10.1111/add.12876.
- Gelernter J, Kranzler HR. Genetics of alcohol dependence. Hum Genet. 2009;126:91–99. doi:https://doi.org/10.1007/s00439-009-0701-2.
- Zhang HP, Herman AI, Kranzler HR, Anton RF, Simen AA, Gelernter J. Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence. J Hum Genet. 2012;57:670–75. doi:https://doi.org/10.1038/jhg.2012.98.
- Zhang HP, Gelernter J. DNA methylation and alcohol use disorders: progress and challenges. Am J Addict. 2017;26:502–15. doi:https://doi.org/10.1111/ajad.12465.
- Ball D. Addiction science and its genetics. Addiction. 2008;103:360–67. doi:https://doi.org/10.1111/j.1360-0443.2007.02061.x.
- Crist RC, Berrettini WH. Pharmacogenetics of OPRM1. Pharmacol Biochem Behav. 2014;123:25–33. doi:https://doi.org/10.1016/j.pbb.2013.10.018.
- Marini V, Fucile C, Zuccoli ML, Testino G, Sumberaz A, Robbiano L, Martelli A, Mattioli F. Involvement of the mu-opioid receptor gene polymorphism A118G in the efficacy of detoxification of alcohol dependent patients. Addict Behav. 2013;38:1669–71. doi:https://doi.org/10.1016/j.addbeh.2012.09.015.
- Woodcock EA, Lundahl LH, Burmeister M, Greenwald MK. Functional mu opioid receptor polymorphism (OPRM1 A(118) G) associated with heroin use outcomes in Caucasian males: a pilot study. Am J Addict. 2015;24:329–35. doi:https://doi.org/10.1111/ajad.12187.
- Miranda R, Ray L, Justus A, Meyerson LA, Knopik VS, McGeary J, Monti PM. Initial evidence of an association between OPRM1 and adolescent alcohol misuse. Alcohol Clin Exp Res. 2010;34:112–22. doi:https://doi.org/10.1111/j.1530-0277.2009.01073.x.
- Koller G, Zill P, Rujescu D, Ridinger M, Pogarell O, Fehr C, Wodarz N, Bondy B, Soyka M, Preuss UW. Possible association between OPRM1 genetic variance at the 118 locus and alcohol dependence in a large treatment sample: relationship to alcohol dependence symptoms. Alcohol Clin Exp Res. 2012;36:1230–36. doi:https://doi.org/10.1111/j.1530-0277.2011.01714.x.
- Bart G, Kreek MJ, Ott J, LaForge KS, Proudnikov D, Pollak L, Heilig M. Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacol. 2005;30:417–22. doi:https://doi.org/10.1038/sj.npp.1300598.
- Deb I, Chakraborty J, Gangopadhyay PK, Choudhury SR, Das S. Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction. J Neurochem. 2010;112:486–96. doi:https://doi.org/10.1111/j.1471-4159.2009.06472.x.
- Nishizawa D, Han WH, Hasegawa J, Ishida T, Numata Y, Sato T, Kawai A, Ikeda K. Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population. Neuropsychobiology. 2006;53:137–41. doi:https://doi.org/10.1159/000093099.
- Chen DY, Liu L, Xiao Y, Peng YH, Yang CW, Wang ZZ. Ethnic-specific meta-analyses of association between the OPRM1 A118G polymorphism and alcohol dependence among Asians and Caucasians. Drug Alcohol Depend. 2012;123:1–6. doi:https://doi.org/10.1016/j.drugalcdep.2011.10.012.
- Zhang HP, Luo XG, Kranzler HR, Lappalainen J, Yang BZ, Krupitsky E, Zvartau E, Gelernter J. Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. Hum Mol Genet. 2006;15:807–19. doi:https://doi.org/10.1093/hmg/ddl024.
- Quillen EE, Chen XD, Almasy L, Yang F, He H, Li X, Wang XY, Liu TQ, Hao W, Deng HW, et al. ALDH2 is associated to alcohol dependence and is the major genetic determinant of “daily maximum drinks” in a GWAS study of an isolated rural Chinese sample. Am J Med Genet B Neuropsychiatr Genet. 2014;165:103–10.
- Fischer M, Wetherill LF, Carr LG, You M, Crabb DW. Association of the aldehyde dehydrogenase 2 promoter polymorphism with alcohol consumption and reactions in an American Jewish population. Alcohol Clin Exp Res. 2007;31:1654–59. doi:https://doi.org/10.1111/j.1530-0277.2007.00471.x.
- Zhang FF, Hou LF, Terry MB, Lissowska J, Morabia A, Chen JB, Yeager M, Zatonski W, Chanock S, Chow WH. Genetic polymorphisms in alcohol metabolism, alcohol intake and the risk of stomach cancer in Warsaw, Poland. Int J Cancer. 2007;121:2060–64. doi:https://doi.org/10.1002/ijc.22973.
- Huang CY, Shen W, Zhu M, Wang C, Ma HX, Shen HB. Associations between single nucleotide polymorphisms (SNPs) with acetaldehyde dehydrogenase gene 2 (ALDH2) and male drinking behavior. Chin J Dis Control Prevention. 2015;6:539–42.
- Pathak H, Frieling H, Bleich S, Glahn A, Heberlein A, Nassab MH, Hillemacher T, Burkert A, Rhein M. Promoter polymorphism rs886205 genotype interacts with DNA methylation of the ALDH2 regulatory region in alcohol dependence. Alcohol Alcohol. 2017;52:269–76.
- Nassab MH, Rhein M, Hagemeier L, Kaeser M, Muschler M, Glahn A, Pich A, Heberlein A, Kornhuber J, Bleich S, et al. Impaired regulation of ALDH2 protein expression revealing a yet unknown epigenetic impact of rs886205 on specific methylation of a negative regulatory promoter region inalcohol-dependent patients. Eur Addict Res. 2016;22:59–69.
- Selzer ML. The Michigan alcoholism screening test (MAST): the quest for a new diagnostic instrument.[J]. Amer.j.psychiat. 1971;127:1653–58. doi:https://doi.org/10.1176/ajp.127.12.1653.
- Saunders JB, Aasland OG, Babor TF,de la Fuente JR, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption–II.[J]. Addiction. 1993;88:791–804.
- Madden PA, Heath AC, Starmer GA, Whitfield JB, Martin NG. Alcohol sensitivity and smoking history in men and women. Alcohol Clin Exp Res. 1995;19:1111–20. doi:https://doi.org/10.1111/j.1530-0277.1995.tb01588.x.
- Bucholz KK, Heath AC, Madden PA. Transitions in drinking in adolescent females: evidence from the Missouri adolescent female twin study. Alcohol Clin Exp Res. 2000;24:914–23.doi:https://doi.org/10.1111/j.1530-0277.2000.tb02073.x.
- Verplaetse TL, McKee SA. An overview of alcohol and tobacco/nicotine interactions in the human laboratory. Am J Drug Alcohol Abuse. 2017;43:186–96. doi:https://doi.org/10.1080/00952990.2016.1189927.
- Xu HQ, Wang F, Kranzler HR, Gelernter J, Zhang HP. Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes. Sci Rep. 2017;7:41816. doi:https://doi.org/10.1038/srep41816.
- Nielsen DA, Yuferov V, Hamon S, Jackson C, Ho A, Ott J, Kreek MJ. Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts. Neuropsychopharmacol. 2009;34:867–73. doi:https://doi.org/10.1038/npp.2008.108.
- Nielsen DA, Hamon S, Yuferov V, Jackson C, Ho A, Ott J, Kreek MJ. Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts. Hum Genet. 2010;127:639–49. doi:https://doi.org/10.1007/s00439-010-0807-6.
- Chorbov VM, Todorov AA, Lynskey MT, Cicero TJ. Elevated levels of DNA methylation at the OPRM1 promoter in blood and sperm from male opioid addicts. J Opioid Manag. 2011;7:258–64. doi:https://doi.org/10.5055/jom.2011.0067.
- Ebrahimi G, Asadikaram G, Akbari H, Nematollahi MH, Abolhassani M, Shahabinejad G, Khodadadnejad L, Hashemi M. Elevated levels of DNA methylation at the OPRM1 promoter region in men with opioid use disorder. Am J Drug Alcohol Abuse. 2018;44:193–99. doi:https://doi.org/10.1080/00952990.2016.1275659.
- Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH. Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Mol Cell Biol. 2007;27:4720–36. doi:https://doi.org/10.1128/MCB.00073-07.