419
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Genetic testing for hereditary cancer: Effects of alexithymia and coping strategies on variations in anxiety before and after result disclosure

, , , &
Pages 855-873 | Received 17 Oct 2009, Accepted 01 Jul 2010, Published online: 23 Mar 2011

References

  • Aktan-Collan , K , Haukkala , A , Mecklin , JP , Uutela , A and Kaariainen , H . 2001 . Psychological consequences of predictive genetic testing for hereditary non-polyposis colorectal cancer (HNPCC): A prospective follow-up study . International Journal of Cancer , 93 ( 4 ) : 608 – 611 .
  • Audrain , J , Rimer , B , Cella , D , Stefanek , M , Garber , J , Pennanen , M Lerman , C . 1999 . The impact of a brief coping skills intervention on adherence to breast self-examination among first-degree relatives of newly diagnosed breast cancer patients . Psycho-oncology , 8 ( 3 ) : 220 – 229 .
  • Bagby , RM , Parker , JD and Taylor , GJ . 1994 . The twenty-item Toronto Alexithymia Scale-I. Item selection and cross-validation of the factor structure . Journal of Psychosomatic Research , 38 ( 1 ) : 23 – 32 .
  • Baron , RM and Kenny , DA . 1986 . The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations . Journal of Personality and Socical Psychology , 51 ( 6 ) : 1173 – 1182 .
  • Bermond , B . 1997 . “ Brain and Alexithymia ” . In The (non) expression of emotion in health and disease , Edited by: Vingerhoets , A , Van Bussen , F and Boelhouwers , J . 115 – 131 . Tilburg , , The Netherlands : Tilburg University Press .
  • Bolger , N . 1990 . Coping as a personality process: A prospective study . Journal of Personality and Social Psychoology , 59 ( 3 ) : 525 – 537 .
  • Broadstock , M , Michie , S , Gray , J , Mackay , J and Marteau , TM . 2000 . The psychological consequences of offering mutation searching in the family for those at risk of hereditary breast and ovarian cancer – A pilot study . Psychooncology , 9 ( 6 ) : 537 – 548 .
  • Brownlee , S , Leventhal , H and Leventhal , EA . 2000 . “ Regulation, self-regulation, and construction of the self in the maintenance of physical health ” . In Handbook of self-regulation , Edited by: Monique , B , Paul , RP and Moshe , Z . 369 – 416 . San Diego : Academic Press .
  • Bruchon-Schweitzer , ML . 1993 . Manuel de l'inventaire d'anxiété état-trait forme Y (STAI-Y) de Spielberger , Paris : ECPA .
  • Bruchon-Schweitzer , ML . 2002 . Psychologie de la santé. Modèles, concepts et méthodes , Paris : Dunod .
  • Butow , PN , Lobb , EA , Meiser , B , Barratt , A and Tucker , KM . 2003 . Psychological outcomes and risk perception after genetic testing and counselling in breast cancer: A systematic review . The Medical Journal of Australia , 178 ( 2 ) : 77 – 81 .
  • Carver, C.S. (2000). Influences of personality and coping variables on health behaviors and health outcomes. Compendium of Continuing Education in Dentistry, 30(Suppl), 49–56; quiz 66–47.
  • Chin , WW . 1998 . “ The partial least squares approach for structural equation modeling ” . In Modern methods for business research , Edited by: Marcoulides , GA . 295 – 336 . London : Lawrence Erlbaum Associates .
  • Claes , E , Denayer , L , Evers-Kiebooms , G , Boogaerts , A and Legius , E . 2004 . Predictive testing for hereditary non-polyposis colorectal cancer: Motivation, illness representations and short-term psychological impact . Patient Education and Counseling , 55 ( 2 ) : 265 – 274 .
  • Cohen , J . 1992 . A power primer . Psychological Bulletin , 112 ( 1 ) : 155 – 159 .
  • Cousson , F , Bruchon-Schweitzer , ML , Quintard , B , Nuissier , J and Rascle , N . 1996 . Analyse multidimentionnelle d’une échelle de coping : Validation française de la W.C.C (ways of coping checklist) . Psychologie Française , 41 ( 2 ) : 155 – 164 .
  • Croyle , RT , Smith , KR , Botkin , JR , Baty , B and Nash , J . 1997 . Psychological responses to BRCA1 mutation testing: Preliminary findings . Health Psychology , 16 ( 1 ) : 63 – 72 .
  • De Vente , W , Kamphuis , JH and Emmelkamp , PMG . 2006 . Alexithymia, risk factor or consequence of work-related stress? . Psychotherapy and Psychosomatics , 75 ( 5 ) : 304 – 311 .
  • Endler , NS . 1997 . Stress, anxiety and coping: The multidimensional interaction model . Canadian Psychology , 38 ( 3 ) : 136 – 153 .
  • Fantini-Hauwel, C., Manouvrier, S., & Pedinielli, J L. (2007). A Multidimensional Approach to Genetic Testing: How Alexithymia Influences Emotional Pathways of Adjustment. Paper presented at the 21st Conference of the EHPS “Health Psychology and Society” 15th–18th August, 2007, Maastricht, The Netherlands.
  • Fantini-Hauwel, C., & Pedinielli, J.L. (2007). Absolute and Relative Stability of Alexithymia: A Third Way of Reflection. Paper presented at the EHPS 2007: “Health Psychology and Society”.
  • Fantini-Hauwel , C and Pedinielli , JL . 2008 . De la non-expression à la surexpression des émotions ou comment l'expérience émotionnelle repose la question des liens entre sexe, alexithymie et répression . Annales Médico-Psychologiques , 166 ( 4 ) : 277 – 284 .
  • Flett, G.L., Blankstein, K.R., & Obertynski, M. (1996). Affect intensity, coping styles, mood regulation expectancies and depressive symptoms. Personality and individual differences, 20, 221–228.
  • Fornell , C and Bookstein , F . 1982 . “ A comparative analysis of two structural equation models: LISREL and PLS applied to market data ” . In A second general of multivariate analysis , Edited by: Fornell , C . Vol. 1 , 289 – 323 . New York : Praeger .
  • Freyberger , H . 1977 . Supportive psychotherapeutic techniques in primary and secondary alexithymia . Psychotherapy and Psychosomatics , 28 ( 1–4 ) : 337 – 342 .
  • Fukunishi , I . 1992 . Psychosomatic problems surrounding kidney transplantation: Incidence of alexithymia and psychiatric disturbances . Psychotherapy and Psychosomatics , 57 ( 1–2 ) : 42 – 49 .
  • Fukunishi , I , Kikuchi , M , Wogan , J and Takubo , M . 1997 . Secondary alexithymia as a state reaction in panic disorder and social phobia . Comprehensive Psychiatry , 38 ( 3 ) : 166 – 170 .
  • Fukunishi , I , Saito , S and Ozaki , S . 1992 . The influence of defense mechanisms on secondary alexithymia in hemodialysis patients . Psychotherapy and Psychosomatics , 57 ( 1–2 ) : 50 – 56 .
  • Gefen , D , Straub , D and Boudreau , M . 2000 . Structural equation modeling and regression: Guidelines for research practice . Communications of the Association for Information Systems , 4 : 1 – 80 .
  • Geirdal , AO and Dahl , AA . 2008 . The relationship between coping strategies and anxiety in women from families with familial breast-ovarian cancer in the absence of demonstrated mutations . Psychooncology , 17 ( 1 ) : 49 – 57 .
  • Gritz , ER , Peterson , SK , Vernon , SW , Marani , SK , Baile , WF , Watts , BG Lynch , PM . 2005 . Psychological impact of genetic testing for hereditary nonpolyposis colorectal cancer . Journal of Clinical Oncology , 23 ( 9 ) : 1902 – 1910 .
  • Heshka , JT , Palleschi , C , Howley , H , Wilson , B and Wells , PS . 2008 . A systematic review of perceived risks, psychological and behavioral impacts of genetic testing . Genetics in Medicine , 10 ( 1 ) : 19 – 32 .
  • Horowitz , M . 1996 . Stress response syndromes: PTSD, grief, and adjustment disorders (Rev. 3rd ed.) , Northvale NJ : Jason Aronson .
  • Kelley , JE , Lumley , MA and Leisen , JC . 1997 . Health effects of emotional disclosure in rheumatoid arthritis patients . Health Psychology , 16 ( 4 ) : 331 – 340 .
  • Kojima , M , Frasure-Smith , N and Lesperance , F . 2001 . Alexithymia following myocardial infarction: Psychometric properties and correlates of the Toronto Alexithymia Scale . Journal of Psychosomatic Research , 51 ( 3 ) : 487 – 495 .
  • Krystal , H . 1988 . Integration and selfhealing: Affect, trauma, alexithymia , Hillsdale , NJ : Analytic Press .
  • Lazarus , RS . 1984 . Emotion and adaptation , New York, Oxford : Oxford University Press .
  • Leventhal, H., Benyamini, Y., Brownlee, S., Diefenbach, M., Leventhal, E.A., Miller, L.P., & Robitaille, C. (1998). Illness representations theoretical foundations. In K.J. Petrie, J. Weinman (Eds.). Perceptions of Health and Illness: Current Research and Applications. Hove, UK: Psychology Press.
  • Loas , G , Fremaux , D and Marchand , MP . 1995 . Factorial structure and internal consistency of the French version of the twenty-item Toronto Alexithymia Scale in a group of 183 healthy probands . Encephale , 21 ( 2 ) : 117 – 122 .
  • Loas , G , Otmani , O , Verrier , A , Fremaux , D and Marchand , MP . 1996 . Factor analysis of the French version of the 20-Item Toronto Alexithymia Scale (TAS-20) . Psychopathology , 29 ( 2 ) : 139 – 144 .
  • Lohmoeller , J . 1989 . Latent variable path modeling with partial least squares , New York : Springer-Verlag .
  • Luminet , O , Bagby , RM and Taylor , GJ . 2001 . An evaluation of the absolute and relative stability of alexithymia in patients with major depression . Psychotherapy and Psychosomatics , 70 ( 5 ) : 254 – 260 .
  • Luminet , O , Rokbani , L , Ogez , D and Jadoulle , V . 2007 . An evaluation of the absolute and relative stability of alexithymia in women with breast cancer . Journal of Psychosomatic Research , 62 ( 6 ) : 641 – 648 .
  • Lynch , HT and Smyrk , T . 1996 . Hereditary nonpolyposis colorectal cancer (Lynch syndrome): An updated review . Cancer , 78 ( 6 ) : 1149 – 1167 .
  • MacKinnon , DP , Lockwood , CM , Hoffman , JM , West , SG and Sheets , V . 2002 . A comparison of methods to test mediation and other intervening variable effects . Psychological Methods , 7 ( 1 ) : 83 – 104 .
  • Marchesi , C , Brusamonti , E and Maggini , C . 2000 . Are alexithymia, depression, and anxiety distinct constructs in affective disorders? . Journal of Psychosomatic Research , 49 ( 1 ) : 43 – 49 .
  • Marchesi , C , Fontò , S , Balista , C , Cimmino , C and Maggini , C . 2005 . Relationship between Alexithymia and panic disorder: A longitudinal study to answer an open question . Psychotherapy and Psychosomatics , 74 ( 1 ) : 56 – 60 .
  • Meiser , B , Butow , P , Friedlander , M , Barratt , A , Schnieden , V , Watson , M Tucker , K . 2002 . Psychological impact of genetic testing in women from high-risk breast cancer families . European Journal of Cancer , 38 ( 15 ) : 2025 – 2031 .
  • Meiser , B , Collins , V , Warren , R , Gaff , C , St John , DJ , Young , MA Halliday , J . 2004 . Psychological impact of genetic testing for hereditary non-polyposis colorectal cancer . Clinical Genetics , 66 ( 6 ) : 502 – 511 .
  • Murakami , Y , Okamura , H , Sugano , K , Yoshida , T , Kazuma , K , Akechi , T, Uchitomi , Y . 2004 . Psychologic distress after disclosure of genetic test results regarding hereditary nonpolyposis colorectal carcinoma . Cancer , 101 ( 2 ) : 395 – 403 .
  • Nesselroade , J , Stigler , S and Baltes , P . 1980 . Regression toward the mean and the study of change . Psychological Bulletin , 88 ( 3 ) : 622 – 637 .
  • Newman , B , Austin , MA , Lee , M and King , MC . 1988 . Inheritance of human breast cancer: Evidence for autosomal dominant transmission in high-risk families . Proceedings of the National Academy of Sciences of the United States of America , 85 : 3044 – 3048 .
  • Nordin , K , Liden , A , Hansson , M , Rosenquist , R and Berglund , G . 2002 . Coping style, psychological distress, risk perception, and satisfaction in subjects attending genetic counselling for hereditary cancer . Journal of Medical Genetics , 39 ( 9 ) : 689 – 694, 689–694 .
  • Paez , D , Velasco , C and Gonzalez , JL . 1999 . Expressive writing and the role of alexythimia as a dispositional deficit in self-disclosure and psychological health . Journal of Personality and Social Psychology , 77 ( 3 ) : 630 – 641 .
  • Parker , JD , Taylor , GJ and Bagby , RM . 1998 . Alexithymia: Relationship with ego defense and coping styles . Comprehensive Psychiatry , 39 ( 2 ) : 91 – 98 .
  • Payne , SA . 1990 . Coping with palliative chemotherapy . Journal of Advanced Nursing , 15 ( 6 ) : 652 – 658 .
  • Pennebaker , JW , Hughes , CF and O’Heeron , RC . 1987 . The psychophysiology of confession: Linking inhibitory and psychosomatic processes . Journal of Personality and Social Psychology , 52 ( 4 ) : 781 – 793 .
  • Pennebaker , JW and Susman , JR . 1988 . Disclosure of traumas and psychosomatic processes . Social Science and Medicine , 26 ( 3 ) : 327 – 332 .
  • Preacher , KJ and Hayes , AF . 2008 . Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models . Behavior Research Methods , 40 ( 3 ) : 879 – 891 .
  • R Development Core Team. (2010). R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing.
  • Smith , AW , Dougall , AL , Posluszny , DM , Somers , TJ , Rubinstein , WS and Baum , A . 2008 . Psychological distress and quality of life associated with genetic testing for breast cancer risk . Psycho-oncology , 17 ( 8 ) : 767 – 773 .
  • Smyth , J . 1998 . Written emotional expression: Effect sizes, outcome types, and moderating variables . Journal of Consulting and Clinical Psychology , 66 ( 1 ) : 174 – 184 .
  • Spielberger , CD . 1983 . Manual for the State-Trait Anxiety Inventory (Form Y) , Palo Alto : Consulting Psychologist Press .
  • Spielberger, C.D., Gorsuch, R.L., Lushene, R., Vagg, P.R., & Jacobs, G.A. (1993). Manuel de l'inventaire d'anxiété état-trait forme Y (STAI-Y). Adapté par M. Bruchon-Schweitzer et I. Paulhan. Paris: ECPA.
  • Stanton , AL , Danoff-Burg , S , Cameron , CL , Bishop , M , Collins , CA , Kirk , SB Twillman , R . 2000 . Emotionally expressive coping predicts psychological and physical adjustment to breast cancer . Journal of Consulting and Clinical Psychology , 68 ( 5 ) : 875 – 882 .
  • Stanton , AL , Danoff-Burg , S , Cameron , CL and Ellis , AP . 1994 . Coping through emotional approach: Problems of conceptualization and confounding . Journal of Personality and Social Psychology , 66 ( 2 ) : 350 – 362 .
  • Stone, L.A., & Nielson, K.A. (2001). Intact physiological response to arousal with impaired emotional recognition in alexithymia. Psychotherapy and Psychosomatics, 70(2), 92–102.
  • Suls , J and Fletcher , B . 1985 . The relative efficacy of avoidant and nonavoidant coping strategies: A meta-analysis . Health Psychology , 4 ( 3 ) : 249 – 288 .
  • Taylor , GJ . 1997 . Disorders of affect regulation. Alexithymia in medical and psychiatric illness , Cambridge : Cambridge University Press .
  • Taylor , GJ . 2000 . Recent developments in alexithymia theory and research . Canadian Journal of Psychiatry , 45 ( 2 ) : 134 – 142 .
  • Taylor , GJ and Bagby , RM . 2004 . New trends in alexithymia research . Psychotherapy and Psychosomatics , 73 ( 2 ) : 68 – 77 .
  • Tenenhaus, M., Amato, S., & Esposito-Vinzi, V. (2004). A global goodness-of-fit index for PLS structural equation modelling. Paper presented at the Proceedings of the XLII SIS Scientific Meeting, Contributed Papers, CLEUP (pp. 739–742), Padova, Italy.
  • Tenenhaus , M , Vinzi , VE , Chatelin , Y-M and Lauro , C . 2005 . PLS path modeling . Computational Statistics and Data Analysis , 48 ( 1 ) : 159 – 205 .
  • Tercyak , KP , Lerman , C , Peshkin , BN , Hughes , C , Main , D , Isaacs , C Schwartz , MD . 2001 . Effects of coping style and BRCA1 and BRCA2 test results on anxiety among women participating in genetic counseling and testing for breast and ovarian cancer risk . Health Psychology , 20 ( 3 ) : 217 – 222 .
  • Terry , DJ . 1994 . Determinants of coping: The role of stable and situational factors . Journal of Personality and Social Psychology , 66 ( 5 ) : 895 – 910 .
  • Valentiner , DPH , Charles , J and Moos , RH . 1993 . Social support, appraisals of event controllability, and coping: An integrative model . Journal of Personality and Social Psychology , 66 ( 6 ) : 1094 – 1102 .
  • Van Middendorp , H and Geenen , R . 2008 . Poor cognitive-emotional processing may impede the outcome of emotional disclosure interventions . British Journal of Health Psychology , 13 ( 1 ) : 49 – 52 .
  • Van Middendorp , H , Geenen , R , Sorbi , MJ , van Doornen , LJ and Bijlsma , JW . 2005 . Emotion regulation predicts change of perceived health in patients with rheumatoid arthritis . Annals of Rheumatic Disorder , 64 ( 7 ) : 1071 – 1074 .
  • Van Middendorp , H , Lumley , MA , Jacobs , JW , van Doornen , LJ , Bijlsma , JW and Geenen , R . 2008 . Emotions and emotional approach and avoidance strategies in fibromyalgia . Journal of Psychosomatic Research , 64 ( 2 ) : 159 – 167 .
  • Vingerhoets , AJ , Van Heck , GL , Grim , R and Bermond , B . 1995 . Alexithymia: A further exploration of its nomological network . Psychotherapy and Psychosomatic , 64 ( 1 ) : 32 – 42 .
  • Vitaliano , PP , Russo , J , Carr , JE , Maiuro , RD and Becker , J . 1985 . The ways of coping checklist: Revision and psychometric properties . Multivariate Behavioral Research , 20 : 3 – 26 .
  • Wakefield , CE , Homewood , J , Mahmut , M , Taylor , A and Meiser , B . 2007 . Usefulness of the threatening medical situations inventory in individuals considering genetic testing for cancer risk . Patient Education and Counseling , 69 ( 1–3 ) : 29 – 38 .
  • Wise , TN , Mann , LS and Epstein , S . 1991 . Ego defensive styles and alexithymia: A discriminant validation study . Psychotherapy and Psychosomatic , 56 : 141 – 145 .
  • Zimmermann , G , Rossier , J , Meyer de Stadelhofen , F and Gaillard , F . 2005 . Alexithymia assessment and relations with dimensions of personality . European Journal of Psychological Assessment , 21 ( 1 ) : 23 – 33 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.