91
Views
0
CrossRef citations to date
0
Altmetric
Articles

Perceived sensitivity to medicines and medication concerns beliefs predict intentional nonadherence to antiretroviral therapy among young people living with HIV

, &
Pages 931-946 | Received 25 Jan 2022, Accepted 01 Sep 2022, Published online: 16 Sep 2022

References

  • Amico, K. R., Harman, J. J., & Johnson, B. T. (2006). Efficacy of antiretroviral therapy adherence interventions: a research synthesis of trials, 1996 to 2004. Journal of Acquired Immune Deficiency Syndromes (1999), 41(3), 285–297. https://doi.org/10.1097/01.qai.0000197870.99196.ea
  • Ammassari, A., Murri, R., Pezzotti, P., Trotta, M. P., Ravasio, L., & De Longis, P. (2001). Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection. Journal of Acquired Immune Deficiency Syndromes, 28(5), 445–449.
  • Andresen-Streichert, H., Müller, A., Glahn, A., Skopp, G., & Sterneck, M. (2018). Alcohol biomarkers in clinical and forensic contexts. Deutsches Arzteblatt International, 115(18), 309–315.
  • Arts, D. L., Voncken, A. G., Medlock, S., Abu-Hanna, A., & van Weert, H. C. (2016). Reasons for intentional guideline non-adherence: A systematic review. International Journal of Medical Informatics, 89, 55–62. https://doi.org/10.1016/j.ijmedinf.2016.02.009
  • Aujla, N., Walker, M., Sprigg, N., Abrams, K., Massey, A., & Vedhara, K. (2016). Can illness beliefs, from the common-sense model, prospectively predict adherence to self-management behaviours? A systematic review and meta-analysis. Psychology & Health, 31(8), 931–958. https://doi.org/10.1080/08870446.2016.1153640
  • Bangsberg, D. R., & Deeks, S. G. (2002). Is average adherence to HIV antiretroviral therapy enough? Journal of General Internal Medicine, 17(10), 812–813. https://doi.org/10.1046/j.1525-1497.2002.20812.x
  • Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Chesney, M., & Moss, A. (2001). Comparing objective measures of adherence to HIV antiretroviral therapy: Electronic medication monitors and unannounced pill counts. AIDS and Behavior, 5(3), 275–281. https://doi.org/10.1023/A:1011396711486
  • Berg, C., Raminani, S., Greer, J., Harwood, M., & Safren, S. (2008). Participants’ perspectives on cognitive-behavioral therapy for adherence and depression in HIV. Psychotherapy Research: Journal of the Society for Psychotherapy Research, 18(3), 271–280. https://doi.org/10.1080/10503300701561537
  • CDC. (2017). Strategies and emerging interventions for improving medication adherence. https://www.cdc.gov/dhdsp/pubs/docs/SIB_feature_Aug2017.pdf.
  • CDC. (2018). Diagnoses of HIV infection in the United States and dependent areas, 2020. https://www.cdc.gov/hiv/library/reports/hiv-surveillance/vol-31/content/tables.html.
  • CDC. (2019). Understanding the HIV care continuum. https://www.cdc.gov/hiv/pdf/library/factsheets/cdc-hiv-care-continuum.pdf.
  • Crepaz, N., Tang, T., Marks, G., Mugavero, M. J., Espinoza, L., & Hall, H. I. (2016). Durable viral suppression and transmission risk potential among persons with diagnosed HIV infection: United States. Clinical Infectious Diseases, 63(7), 976–983. https://doi.org/10.1093/cid/ciw418
  • El-Krab, R., & Kalichman, S. C. (2021). Alcohol-antiretroviral therapy interactive toxicity beliefs and intentional medication nonadherence: Review of research with implications for interventions. AIDS and Behavior, 25(S3), 251–264. https://doi.org/10.1007/s10461-021-03285-x
  • Finitsis, D. J., Pellowski, J. A., Huedo-Medina, T. B., Fox, M. C., & Kalichman, S. C. (2016). Visual analogue scale (VAS) measurement of antiretroviral adherence in people living with HIV (PLWH): a meta-analysis. Journal of Behavioral Medicine, 39(6), 1043–1055. https://doi.org/10.1007/s10865-016-9770-6
  • Giordano, T. P., Guzman, D., Clark, R., Charlebois, E. D., & Bangsberg, D. (2004). Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scale. HIV Clinical Trials, 5(2), 74–79. https://doi.org/10.1310/JFXH-G3X2-EYM6-D6UG
  • Hayes, A. F. (2013). Model templates for PROCESS for SPSS and SAS. Guilford Press.
  • Heller, M. K., Chapman, S. C., & Horne, R. (2015). Beliefs about medication predict the misattribution of a common symptom as a medication side effect–Evidence from an analogue online study. Journal of Psychosomatic Research, 79(6), 519–529. https://doi.org/10.1016/j.jpsychores.2015.10.003
  • Heller, M. K., Chapman, S. C., & Horne, R. (2017). No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects. Psychology & Health, 32(4), 402–421. https://doi.org/10.1080/08870446.2016.1273355
  • Horne, R., Chapman, S. C., Parham, R., Freemantle, N., Forbes, A., & Cooper, V. (2013). Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework. PLoS One, 8(12), e80633. https://doi.org/10.1371/journal.pone.0080633
  • Horne, R., Chapman, S., Glendinning, E., Date, H. L., Guitart, J., & Cooper, V. (2019). Mind matters: Treatment concerns predict the emergence of antiretroviral therapy side effects in people with HIV. AIDS and Behavior, 23(2), 489–498. https://doi.org/10.1007/s10461-018-2239-6
  • Horne, R., Cooper, V., Gellaitry, G., Date, H. L., & Fisher, M. (2007). Patients’ perceptions of highly active antiretroviral therapy in relation to treatment uptake and adherence: the utility of the necessity-concerns framework. Journal of Acquired Immune Deficiency Syndromes (1999), 45(3), 334–341. https://doi.org/10.1097/QAI.0b013e31806910e3
  • Horne, R., Faasse, K., Cooper, V., Diefenbach, M. A., Leventhal, H., Leventhal, E., & Petrie, K. J. (2013). The perceived sensitivity to medicines (PSM) scale: an evaluation of validity and reliability. British Journal of Health Psychology, 18(1), 18–30. https://doi.org/10.1111/j.2044-8287.2012.02071.x
  • Judd, C. M., & Kenny, D. A. (1981). Process analysis: Estimating mediation in treatment evaluations. Evaluation Review, 5(5), 602–619. https://doi.org/10.1177/0193841X8100500502
  • Kalichman, S. C., Amaral, C. M., Cherry, C., Flanagan, J., Pope, H., Eaton, L., Kalichman, M. O., Cain, D., Detorio, M., Caliendo, A., & Schinazi, R. F. (2008). Monitoring antiretroviral adherence by unannounced pill counts conducted by telephone: Reliability and criterion-related validity. HIV Clinical Trials, 9(5), 298–308. https://doi.org/10.1310/hct0905-298
  • Kalichman, S. C., Amaral, C. M., Stearns, H., White, D., Flanagan, J., Pope, H., Cherry, C., Cain, D., Eaton, L., & Kalichman, M. O. (2007). Adherence to antiretroviral therapy assessed by unannounced pill counts conducted by telephone. Journal of General Internal Medicine, 22(7), 1003–1006. https://doi.org/10.1007/s11606-007-0171-y
  • Kalichman, S. C., Grebler, T., Amaral, C. M., McNerey, M., White, D., Kalichman, M. O., Cherry, C., & Eaton, L. (2013). Intentional non-adherence to medications among HIV positive alcohol drinkers: prospective study of interactive toxicity beliefs. Journal of General Internal Medicine, 28(3), 399–405. https://doi.org/10.1007/s11606-012-2231-1
  • Kalichman, S. C., Horne, R., Katner, H., & Hernandez, D. (2019). Perceived sensitivity to medicines, alcohol interactive toxicity beliefs, and medication adherence among people living with HIV who drink alcohol. Journal of Behavioral Medicine, 42(3), 392–400. https://doi.org/10.1007/s10865-018-9987-7
  • Kalichman, S. C., Kalichman, M. O., Cherry, C., Hoyt, G., Washington, C., Grebler, T., Welles, B., & Merely, C. (2015). Intentional medication nonadherence because of interactive toxicity beliefs among HIV-positive active drug users. Journal of Acquired Immune Deficiency Syndromes (1999), 70(5), 503–509. https://doi.org/10.1097/QAI.0000000000000776
  • Kalichman, S. C., Katner, H., Hill, M., Ewing, W., & Kalichman, M. O. (2021). Perceived sensitivity to medicines and the experience of side-effects: understanding intentional medication nonadherence among people living with HIV. Psychology, Health & Medicine, 1–12. Online ahead of print. https://doi.org/10.1080/13548506.2021.1960391
  • Lailulo, Y., Kitenge, M., Jaffer, S., Aluko, O., & Nyasulu, P. S. (2020). Factors associated with antiretroviral treatment failure among people living with HIV on antiretroviral therapy in resource-poor settings: a systematic review and metaanalysis. Systematic Reviews, 9(1), 292. https://doi.org/10.1186/s13643-020-01524-1
  • Leaver, C. A., Bargh, G., Dunn, J. R., & Hwang, S. W. (2007). The effects of housing status on health-related outcomes in people living with HIV: a systematic review of the literature. AIDS and Behavior, 11(6 Suppl), 85–100. https://doi.org/10.1007/s10461-007-9246-3
  • Lehane, E., & McCarthy, G. (2007). An examination of the intentional and unintentional aspects of medication non-adherence in patients diagnosed with hypertension. Journal of Clinical Nursing, 16(4), 698–706. https://doi.org/10.1111/j.1365-2702.2005.01538.x
  • Locher, C., Messerli, M., Gaab, J., & Gerger, H. (2019). Long-term effects of psychological interventions to improve adherence to antiretroviral treatment in HIV-infected persons: A systematic review and meta-analysis. AIDS Patient Care and STDs, 33(3), 131–144. https://doi.org/10.1089/apc.2018.0164
  • Molecular A. (2020). RealTime HIV-1 assay. Abbott Laboratories Abbott Park, IL. https://www.molecular.abbott/us/en/products/infectious-disease/realtime-hiv-1-viral-load.
  • Norton, W. E., Amico, K. R., Fisher, W. A., Shuper, P. A., Ferrer, R. A., Cornman, D. H., Trayling, C. A., Redding, C., & Fisher, J. D. (2010). Information-motivation-behavioral skills barriers associated with intentional versus unintentional ARV non-adherence behavior among HIV + patients in clinical care. AIDS Care, 22(8), 979–987. https://doi.org/10.1080/09540121003758630
  • Ortego, C., Huedo-Medina, T. B., Llorca, J., Sevilla, L., Santos, P., Rodríguez, E., Warren, M. R., & Vejo, J. (2011). Adherence to highly active antiretroviral therapy (HAART): a meta-analysis. AIDS and Behavior, 15(7), 1381–1396. https://doi.org/10.1007/s10461-011-9942-x
  • Parienti, J.-J., Barrail-Tran, A., Duval, X., Nembot, G., Descamps, D., Vigan, M., Vrijens, B., Panhard, X., Taburet, A.-M., Mentré, F., & Goujard, C. (2013). Adherence profiles and therapeutic responses of treatment-naive HIV-infected patients starting boosted atazanavir-based therapy in the ANRS 134-COPHAR 3 trial. Antimicrobial Agents and Chemotherapy, 57(5), 2265–2271. https://doi.org/10.1128/AAC.02605-12
  • Safren, S. A., O'Cleirigh, C., Tan, J. Y., Raminani, S. R., Reilly, L. C., Otto, M. W., & Mayer, K. H. (2009). A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association, 28(1), 1–10. https://doi.org/10.1037/a0012715
  • Safren, S. A., Otto, M. W., Worth, J. L., Salomon, E., Johnson, W., Mayer, K., & Boswell, S. (2001). Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring. Behaviour Research and Therapy, 39(10), 1151–1162. https://doi.org/10.1016/S0005-7967(00)00091-7
  • Selnes, O. A. (2002). Neurocognitive aspects of medication adherence in HIV infection. Journal of Acquired Immune Deficiency Syndromes, 31(Suppl 3), S132–S5.
  • Shubber, Z., Mills, E. J., Nachega, J. B., Vreeman, R., Freitas, M., Bock, P., Nsanzimana, S., Penazzato, M., Appolo, T., Doherty, M., & Ford, N. (2016). Patient-reported barriers to adherence to antiretroviral therapy: A systematic review and meta-analysis. PLoS Medicine, 13(11), e1002183. https://doi.org/10.1371/journal.pmed.1002183
  • Tang, N., Pahalawatta, V., Frank, A., Bagley, Z., Viana, R., Lampinen, J., Leckie, G., Huang, S., Abravaya, K., & Wallis, C. L. (2017). HIV-1 viral load measurement in venous blood and fingerprick blood using Abbott RealTime HIV-1 DBS assay. Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology, 92, 56–61. https://doi.org/10.1016/j.jcv.2017.05.002
  • Thorneloe, R. J., Griffiths, C. E. M., Emsley, R., Ashcroft, D. M., & Cordingley, L., British Association of Dermatologists Biologic Interventions R. (2018). Intentional and unintentional medication non-adherence in psoriasis: The role of patients’ medication beliefs and habit strength. The Journal of Investigative Dermatology, 138(4), 785–794. https://doi.org/10.1016/j.jid.2017.11.015
  • Thorneloe, R. J., Horne, R., Side, L., Wolf, M. S., Smith, S. G., Adamson, V., Ainsworth, S., Akerlund, M., Baker, I., Barwell, J., Beesley, J., Brock, L., Butcher, C., Carpenter, J., Clark, M., Cocks, S., Conteh, V., Coulding, M., Darby, S., … Wiseman, J. (2019). Beliefs about medication and uptake of preventive therapy in women at increased risk of breast cancer: Results from a multicenter prospective study. Clinical Breast Cancer, 19(1), e116–e26. https://doi.org/10.1016/j.clbc.2018.10.008
  • Weinman, J., Graham, S., Canfield, M., Kleinstäuber, M., Perera, A. I., Dalbeth, N., & Petrie, K. J. (2018). The Intentional Non-Adherence Scale (INAS): Initial development and validation. Journal of Psychosomatic Research, 115, 110–116. https://doi.org/10.1016/j.jpsychores.2018.10.010
  • Weiser, S. D., Bangsberg, D. R., Kegeles, S., Ragland, K., Kushel, M. B., & Frongillo, E. A. (2009). Food insecurity among homeless and marginally housed individuals living with HIV/AIDS in San Francisco. AIDS and Behavior, 13(5), 841–848. https://doi.org/10.1007/s10461-009-9597-z

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.