Advanced search
Publication Cover
Pediatric Hematology and Oncology Volume 38, 2021 - Issue 1
Submit an article Journal homepage
139
Views
1
CrossRef citations to date
0
Altmetric
Article Commentary

Histiocytic sarcoma arising in a child affected by Burkitt lymphoma, with t(8;14)(q24;q32) positivity in both tumors

Emanuele S.G d’Amorea Department of Pathology, San Bortolo Hospital, Vicenza, Italy
,
Chiara Mainardib Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, ItalyORCID Iconhttps://orcid.org/0000-0001-6855-3507
ORCID Icon,
Lara Mussolinb Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, Italy;c Institute of Pediatric Research, Fondazione Città della Speranza, Padova, Italy
,
Elisa Carrarob Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, Italy
,
Rita Alaggiod Department of Pathology, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
,
Elena Lazzaria Department of Pathology, San Bortolo Hospital, Vicenza, Italy
,
Stefano Fusettie Maxillofacial Surgery Unit, Department of Neurosciences, University of Padova Medical School, Padova, Italy
,
Cristina Ghirottof Maxillofacial Surgery Unit, ULSS 3 Serenissima Hospital, Venezia, Italy
,
Antonio Marzollob Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, Italy
,
Giada Biddecib Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, ItalyORCID Iconhttps://orcid.org/0000-0001-8029-2784
ORCID Icon,
Tiziana Toffoluttig Department of Medicine, Pediatric Radiology Unit Radiology Institute Hospital-University of Padova, Padova, Italy
,
Davide Massanob Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, Italy
,
Giovanni Scarzelloh Radiotherapy Department, Istituto Oncologico Veneto-IRCCS, Padova, Italy
,
Monica Zulianig Department of Medicine, Pediatric Radiology Unit Radiology Institute Hospital-University of Padova, Padova, Italy
,
Maria Caterina Puttib Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, ItalyORCID Iconhttps://orcid.org/0000-0001-7218-8645
ORCID Icon,
Alessandra Biffib Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, Italy;c Institute of Pediatric Research, Fondazione Città della Speranza, Padova, Italy;i Gene Therapy Program, Dana Farber/Boston Children’s Cancer and Blood Disorders Centers, Boston, Massachusetts, USAORCID Iconhttps://orcid.org/0000-0002-4610-0870
ORCID Icon &
Marta Pillonb Clinic of Pediatric Haemato-Oncology, Hospital-University of Padova, Padova, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1190-3198
ORCID Icon show all
Pages 1-7 | Received 08 May 2020, Accepted 29 Dec 2020, Published online: 23 Feb 2021

References

  • Emile JF, Abla O, Fraitag S, et al. Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. Blood. 2016;127(22):2672–2682. doi:10.1182/blood-2016-01-690636.
  • Swerdlow S, Campo E, Harris N, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Revised 4th ed.; IARC: Lyon, France, 2017.
  • Bucsky P, Maarten Egeler R. Malignant histiocytic disorders in children. clinical and therapeutic approaches with a nosologic discussion. Hematol. Oncol. Clin. North Am. 1998;12(2):465–471.
  • Skala SL, Lucas DR, Dewar R. Histiocytic sarcoma: review, discussion of transformation from B-cell lymphoma, and differential diagnosis. Arch Pathol Lab Med. 2018;142(11):1322–1329. doi:10.5858/arpa.2018-0220-RA.
  • Feldman AL, Arber DA, Pittaluga S, et al. Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: Evidence for transdifferentiation of the follicular lymphoma clone. Blood. 2008;111(12):5433–5439. doi:10.1182/blood-2007-11-124792.
  • Wang E, Hutchinson CB, Huang Q, et al. Histiocytic sarcoma arising in indolent small B-cell lymphoma: report of two cases with molecular/genetic evidence suggestive of a “'transdifferentiation' during the clonal evolution”. Leuk Lymphoma. 2010;51(5):802–812. doi:10.3109/10428191003699845.
  • Shao H, Xi L, Raffeld M, et al. Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a study of seven cases. Mod Pathol. 2011;24(11):1421–1432. doi:10.1038/modpathol.2011.102.
  • Soslow RA, Davis RE, Warnke RA, Cleary ML, Kamel OW. True histiocytic lymphoma following therapy for lymphoblastic neoplasms. Blood. 1996;87(12):5207–5212.
  • Kumar R, Khan SP, Joshi DD, et al. Pediatric histiocytic sarcoma clonally related to precursor B-cell acute lymphoblastic leukemia with homozygous deletion of CDKN2A encoding p16INK4A. Pediatr Blood Cancer. 2011;56(2):307–310. doi:10.1002/pbc.22810.
  • Pillon M, Mussolin L, Carraro E, et al. Detection of prognostic factors in children and adolescents with Burkitt and diffuse large B-cell lymphoma treated with the AIEOP LNH-97 protocol. Br J Haematol. 2016;175(3):467–475. doi:10.1111/bjh.14240.
  • Griffin TC, Weitzman S, Weinstein H, et al. A study of rituximab and ifosfamide, carboplatin, and etoposide chemotherapy in children with recurrent/refractory B-cell (CD20+) non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2009;52(2):177–181. doi:10.1002/pbc.21753.
  • Dunleavy K, Pittaluga S, Maeda L, et al. Dose-adjusted EPOCH-Rituximab therapy in primary mediastinal B-cell lymphoma. N Engl J Med. 2013;368(15):1408–1416. doi:10.1056/NEJMoa1214561.
  • Ornvold K, Carstensen H, Junge J, Gyhrs A, Ralfkiaer E. Tumours classified as “malignant histiocytosis” in children are T-cell neoplasms. APMIS. 1992;100(6):558–566. doi:10.1111/j.1699-0463.1992.tb00911.x.
  • Shanmugam V, Griffin GK, Jacobsen ED, et al. Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma. Mod Pathol. 2019;32(6):830–843. doi:10.1038/s41379-018-0200-x.
  • Castro ECC, Blazquez C, Boyd J, et al. Clinicopathologic features of histiocytic lesions following ALL, with a review of the literature. Pediatr Dev Pathol. 2010;13(3):225–237. doi:10.2350/09-03-0622-OA.1.
  • Xie H, Ye M, Feng R, Graf T, York N. Stepwise reprogramming of B cells into macrophages. Cell. 2004;117(5):663–676. doi:10.1016/S0092-8674(04)00419-2.
  • Cobaleda C, Jochum W, Busslinger M. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature. 2007;449(7161):473–477. doi:10.1038/nature06159.
  • Mainardi C, D'Amore ESG, Pillon M, Toffolutti T, Rosolen A. A case of resistant pediatric histiocytic sarcoma successfully treated with chemo-radiotherapy and autologous peripheral blood stem cell transplant. Leuk Lymphoma. 2011;52(7):1367–1371. doi:10.3109/10428194.2011.565840.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.