Metabolic stability and inhibitory effect of O-methylated theaflavins on H₂O₂-induced oxidative damage in human HepG2 cells

References

• Yang Z, Tu Y, Xia H, Jie G, Chen X, He P. Suppression of free-radicals and protection against H2O2-induced oxidative damage in HPF-1 cell by oxidized phenolic compounds present in black tea. Food Chem. 2007;105:1349–1356.10.1016/j.foodchem.2007.05.006
   Web of Science ®Google Scholar
• Lin JK, Chen PC, Ho CT, Lin-Shiau SY. Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3,3′-digallate, (-)-epigallocatechin-3-gallate, and propyl gallate. J. Agric. Food Chem. 2000;48:2736–2743.10.1021/jf000066d
   PubMed Web of Science ®Google Scholar
• Feng Q, Torii Y, Uchida K, Nakamura Y, Hara Y, Osawa T. Black tea polyphenols, theaflavins, prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P450 1A1 in cell cultures. J. Agric. Food Chem. 2002;50:213–220.10.1021/jf010875c
   PubMed Web of Science ®Google Scholar
• Nishimura M, Ishiyama K, Watanabe A, Kawano S, Miyase T, Sano M. Determination of theaflavins including methylated theaflavins in black tea leaves by solid-phase extraction and HPLC analysis. J. Agric. Food Chem. 2007;55:7252–7257.10.1021/jf070312m
   PubMed Web of Science ®Google Scholar
• Tanaka Y, Kirita M, Miyata S, Abe Y, Tagashira M, Kanda T, Maeda-Yamamoto M. O-Methylated theaflavins suppress the intracellular accumulation of triglycerides from terminally differentiated human visceral adipocytes. J. Agric. Food Chem. 2013;61:12634–12639.10.1021/jf404446h
   PubMed Web of Science ®Google Scholar
• Ishiyama K, Nishimura M, Deguchi M, Terasaka E, Miyase T, Sano M. Enzymatic preparation of methylated theaflavins and their antioxidant activities. Nippon Shokuhin Kagaku Kogaku Kaishi (in Japanese). 2013;60:339–346.10.3136/nskkk.60.339
   Web of Science ®Google Scholar
• Wen X, Walle T. Methylated flavonoids have greatly improved intestinal absorption and metabolic stability. Drug Metabol. Dispos. 2006;34:1786–1792.10.1124/dmd.106.011122
   PubMed Web of Science ®Google Scholar
• Puiggròs F, Llópiz N, Ardévol A, Bladé C, Arola L, Salvadó MJ. Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems. J. Agric. Food Chem. 2005;53:6080–6086.10.1021/jf050343m
   PubMed Web of Science ®Google Scholar
• Okushio K, Suzuki M, Matsumoto N, Nanjo F, Hara Y. Methylation of tea catechins by rat liver homogenates. Biosci. Biotechnol. Biochem. 1999;63:430–432.10.1271/bbb.63.430
   PubMed Web of Science ®Google Scholar
• Dou J, Lee VSY, Tzen JTC, Lee MR. Identification and comparison of phenolic compounds in the preparation of oolong tea manufactured by semifermentation and drying processes. J. Agric. Food Chem. 2007;55:7462–7468.10.1021/jf0718603
   PubMed Web of Science ®Google Scholar
• Gao S, Feng N, Yu S, Yu D, Wang X. Vasodilator constituents from the roots of Lysidice rhodostega. Planta Med. 2004;70:1128–1134.10.1055/s-2004-835839
   PubMed Web of Science ®Google Scholar
• Watanabe M. Catechins as antioxidants from buckwheat (Fagopyrum esculentum Moench) groats. J. Agric. Food Chem. 1998;46:839–845.10.1021/jf9707546
   Web of Science ®Google Scholar
• Mulder TPJ, Van Platerink CJ, Wijnand Schuyl PJ, Van Amelsvoort JMM. Analysis of theaflavins in biological fluids using liquid chromatography-electrospray mass spectrometry. J. Chromatogr. B. 2001;760:271–279.10.1016/S0378-4347(01)00285-7
   PubMed Web of Science ®Google Scholar
• Kirita M, Honma D, Tanaka Y, Usui S, Shoji T, Sami M, Yokota T, Tagashira M, Muranaka A, Uchiyama M, Kanda T, Maeda-Yamamoto M. Cloning of a novel O-methyltransferase from camellia sinensis and synthesis of O-methylated EGCG and evaluation of their bioactivity. J. Agric. Food Chem. 2010;58:7196–7201.10.1021/jf100493s
   PubMed Web of Science ®Google Scholar
• Spencer JPE, Abd El Mohsen MM, Rice-Evans C. Cellular uptake and metabolism of flavonoids and their metabolites: Implications for their bioactivity. Arch. Biochem. Biophys. 2004;423:148–161.10.1016/j.abb.2003.11.010
   PubMed Web of Science ®Google Scholar