The Canadian environment for innovation and business development in the biotechnology industry: a firm‐level analysis

References

• Amit , R , Brander , J and Zott , C . (1998) . Why do Venture Capital Firms Exist? Theory and Canadian Evidence . Journal of Business Venturing , 13 (6) : pp. 441–466
   Web of Science ®Google Scholar
• Arundel , A and Rose , A . (1999) . The Diffusion of Environmental Biotechnology in Canada: Adoption Strategies and Cost Offsets . Technovation , 19 (9) : pp. 551–560
   Web of Science ®Google Scholar
• Audretsch , DB and Stephan , PE . (1996) . Company‐Scientist Locational Links: The Case of Biotechnology . The American Economic Review , 86 (3) : pp. 641–652
   Web of Science ®Google Scholar
• Audretsch , D and Stephan , P . (2000) . Knowledge spillovers in biotechnology: sources and incentives . Journal of Evolutionary Economics , 9 : pp. 97–107
   Web of Science ®Google Scholar
• Bagchi‐Sen , S , Hall , L and Petryshan , L . (2001) . A Study of University‐industry Linkages in the Biotechnology Industry: Perspectives from Canada . International Journal of Biotechnology , 3 (3/4) : pp. 390–410
   Google Scholar
• Belem , MAF . (1999) . Application of Biotechnology in the Product Development of Nutraceuticals in Canada . Trends in Food Science and Technology , 10 (3) : pp. 101–106
   Web of Science ®Google Scholar
• BRAVO – Industry Canada (2003) BRAVO Introduction http://www.bravo.ic.gc.ca/biotech/body.htm
   Google Scholar
• Canadian Biotechnology Advisory Committee (2003) Canadian Biotechnology Advisory Committee – About Us http://cbac‐cccb.ca/epic/internet/incbac‐cccb.nsf/vwGeneratedInterE/h_ah0002e.html
   Google Scholar
• Canadian Biotechnology Strategy (1998) CBS Online – Related Resources Documents: 1983 National Biotechnology Strategy http://biotech.gc.ca/archives/engdoc/bh00194e.html
   Google Scholar
• Cooke P (2002) Rational drug design and the rise of bioscience megacentres Presented at the Fourth Triple Helix Conference on Breaking Boundaries‐Building Bridges, Copenhagen, Denmark‐Lund, Sweden, November 6–9
   Google Scholar
• Cooke P (1998) Introduction: origins of the concept In Braczyk H‐J Cooke P Heindenreich M Regional Innovation Systems (Eds) pp. 2–27 London, UK: UCL Press
   Google Scholar
• Coombs , JE and Deeds , DL . (2000) . International alliances as sources of capital: evidence from the biotechnology industry . The Journal of High Technology Management Research , 11 (2) : pp. 235–253
   Google Scholar
• Cumby J Conrod J (2001) Assessing Value Creation in the Canadian Biotechnology Industry Proceedings of the 31st Annual Atlantic Schools of Business Conference Halifax, Nova Scotia
   Google Scholar
• Gertler , MS . (2001a) . Central Canada and the Global Economy: Politics and Possibilities . Canadian Geographer , 45 (1) : pp. 31–35
   Web of Science ®Google Scholar
• Gertler , MS . (2001b) . Urban Economy and Society in Canada: Flows of People, Capital and Ideas . The Canadian Journal of Policy Research , 2 (3) : pp. 119–130
   Google Scholar
• Gertler , MS , Wolfe , DA and Garkut , D . (2000) . No Place Like Home? The Embeddedness of Innovation in a Regional Economy . Review of International Political Economy , 7 (4) : pp. 688–718
   Web of Science ®Google Scholar
• Government of Canada (2002) Biotechnology Advancing Society, Canada Leading the Way Canadian Biotechnology Advisory Committee, http://cbac‐cccb.ca
   Google Scholar
• Hall S (1987) Invisible Frontiers: The Race to Synthesize a Human Gene London: Sidgwick and Jackson
   Google Scholar
• Hall , L and Bagchi‐Sen , S . (2002) . A Study of R&D, innovation and business performance in the Canadian biotechnology industry . Technovation , 22 : pp. 231–244
   Web of Science ®Google Scholar
• Hall , L and Bagchi‐Sen , S . (2001) . An Analysis of R&D, innovation and business performance in the US biotechnology industry . International Journal of Biotechnology , 3 (3/4) : pp. 267–286
   Google Scholar
• Li , S and Tomalin , A . (2002) . Patentees Research and Development Expenditure in Canada . Journal of Pharmaceutical Science , 5 (1) : pp. 5–11
   Web of Science ®Google Scholar
• Liebeskind JP Oliver AL Zucker LG Brewer MB (1995) Social Networks, Learning and Flexibility: Sourcing Scientific Knowledge in New Biotechnology Firms NBER Working Paper Series, No. 5320. National Bureau of Economic Research, Cambridge, MA
   Google Scholar
• Malecki EJ (1997) Technology and Economic Development Essex, UK: Addison Wesley Longman Limited
   Google Scholar
• McNiven C (2001) Biotechnology Use and Development – 1999 Statistics Canada, Cat. No. 88F0006XIE01007
   Google Scholar
• Nightingale , P . (2000) . Economies of Scale in Experimentation: Knowledge and Technology in Pharmaceutical R&D . Industrial and Corporate Change , 9 : pp. 315–359
   Google Scholar
• Niosi , J and Bas , T . (2001) . The Competencies of Regions – Canada's Clusters in Biotechnology . Small Business Economics , 17 : pp. 31–42
   Web of Science ®Google Scholar
• National Research Council Canada (2003) Biotechnology – National Research Council http://www.nrc‐cnrc.gc.ca/randd/areas/biotechnology_e.html
   Google Scholar
• Oinas , P and Malecki , EJ . (2002) . The evolution of technologies in time and space: from national and regional to spatial innovation systems . International Regional Science Review , 25 : pp. 102–131
   Web of Science ®Google Scholar
• Patented Medicine Prices Review Board (2002a) New Patented Medicines Reported to PMPRB – 2002
   Google Scholar
• Patented Medicine Prices Review Board (2002b) New Patented Medicines Reported to PMPRB – 2001
   Google Scholar
• Patented Medicine Prices Review Board (2002c) New Patented Medicines Reported to PMPRB – 2000
   Google Scholar
• Patented Medicine Prices Review Board (2002d) New Patented Medicines Reported to PMPRB – 1999
   Google Scholar
• Patented Medicine Prices Review Board (2002e) New Patented Medicines Reported to PMPRB – 1998
   Google Scholar
• Pisano , G . (1991) . The governance of innovation: vertical integration and collaborative arrangements in the biotechnology industry . Research Policy , 20 : pp. 237–249
   Web of Science ®Google Scholar
• Pisano G Shan W Teece DJ (1988) Joint ventures and collaboration in the biotechnology industry in Mowery D (Ed.) International Collaborative Ventures in U.S. Manufacturing Cambridge, MA: Ballinger Publishing Co
   Google Scholar
• Powell , WW , Koput , KW , Bowie , JI and Smith‐Doerr , L . (2002) . The spatial clustering of science and capital: accounting for biotech firm‐venture capital relationships . Regional Studies , 36 (3) : pp. 291–305
   Web of Science ®Google Scholar
• Prevezer M (1998) Clustering in Biotechnology in the USA In Peter Swann GM Prevezer M Stout D The Dynamics of Industrial Clustering pp. 124–193 Oxford: Oxford University Press
   Google Scholar
• Rose A (1998) Biotechnology Use by Canadian Industry – 1996 Science and Technology Redesign Project, Statistics Canada, ST‐98–05
   Google Scholar
• Strachan , G . (1995) . The Impact of Regulations on the Growth and Evolution of Canadian Commercial Biotechnology . Current Opinion in Biotechnology , 6 (3) : pp. 261–263
   Web of Science ®Google Scholar
• Strategis Canada (2002) The Biotechnology Gateway: Overview of Biotechnology http://strategis.ic.gc.ca/SSG/bo01544e.html
   Google Scholar
• Statistics Canada (2002a) We Have Learned a Great Deal! Innovation Analysis Bulletin 4 (1) pp. 3–6
   Google Scholar
• Statistics Canada (2002b) IP Protection Practices by Manufacturing Firms Innovation Analysis Bulletin 4 (1) pp. 7–10
   Google Scholar
• Statistics Canada (2002c) A Profile of Spin‐off Firms in the Biotechnology Sector Innovation Analysis Bulletin 4 (1) pp. 12
   Google Scholar
• Swann GM, Peter Prevezer M Stout D (1998) The Dynamics of Industrial Clustering Oxford, UK: Oxford University Press
   Google Scholar
• White K (2000) Economic Profile of the Biotechnology Sector The Canadian Biotechnology Advisory Committee Project Steering Committee Intellectual Property and the Patenting of Higher Life Forms
   Google Scholar
• Woiceshyn , J and Hartel , D . (1996) . Strategies and Performance of Canadian Biotechnology Firms: An Empirical Investigation . Technovation , 16 (5) : pp. 231–243
   Web of Science ®Google Scholar
• Wolfe , DA and Gertler , MS . (2001) . Globalization and Economic Restructuring in Ontario: From Industrial Heartland to Learning Region . European Planning Studies , 9 (5) : pp. 575–592
   Web of Science ®Google Scholar
• Zucker , LG , Darby , MR and Armstrong , JS . (2002) . Commercializing knowledge: university science, knowledge capture, and firm performance in biotechnology . Management Science , 48 (1) : pp. 138–153
   Web of Science ®Google Scholar
• Zucker , LG , Darby , MR and Brewer , MB . (1998) . Intellectual Human Capital and the Birth of U.S. Biotechnology Enterprises . American Economic Review , 88 (1) : pp. 290–306
   Web of Science ®Google Scholar