545
Views
25
CrossRef citations to date
0
Altmetric
Original Articles

On the Nature and Geography of Innovation and Interactive Learning: A Case Study of the Biotechnology Industry in the Aachen Technology Region, Germany

&
Pages 1141-1163 | Received 01 Dec 2009, Accepted 01 Sep 2010, Published online: 02 Aug 2011

References

  • Amin , A. and Cohendet , P. 2004 . Architectures of Knowledge: Firms, Capabilities, and Communities , Oxford : Oxford University Press .
  • Asheim , B. T. and Coenen , L. 2005 . Knowledge bases and regional innovation systems: Comparing Nordic clusters . Research Policy , 34 ( 8 ) : 1173 – 1190 .
  • Asheim , B. T. and Gertler , M. S. 2005 . “ The geography of innovation: Regional innovation systems ” . In The Oxford Handbook of Innovation , Edited by: Fagerberg , J. , Mowery , D. C. and Nelson , R. R. 291 – 317 . Oxford : Oxford University Press .
  • Asheim, B. T., Boschma, R. A. & Cooke, P. (2011) Constructing regional advantage: Platform policies based on related variety and differentiated knowledge bases. Regional Studies, forthcoming. DOI: 10.1080/00343404.2010.543126
  • Asheim , B. T. , Coenen , L. , Moodysson , J. and Vang , J. 2007a . Constructing knowledge-based regional advantage: Implications for regional innovation policy . International Journal of Entrepreneurship and Innovation Management , 7 ( 2–5 ) : 140 – 155 .
  • Asheim , B. T. , Coenen , L. and Vang , J. 2007b . Face-to-face, buzz, and knowledge bases: Sociospatial implications for learning, innovation, and innovation policy . Environment and Planning C: Government and Policy , 25 ( 5 ) : 655 – 670 .
  • Audretsch , B. 1998 . Agglomeration and the location of innovative activity . Oxford Review of Economic Policy , 14 ( 2 ) : 18 – 29 .
  • Autio , E. 1998 . Evaluation of RTD in regional systems of innovation . European Planning Studies , 6 ( 2 ) : 131 – 140 .
  • Bathelt , H. , Malmberg , A. and Maskell , P. 2004 . Clusters and knowledge: Local buzz, global pipelines and the process of knowledge creation . Progress in Human Geography , 28 ( 1 ) : 31 – 56 .
  • Borgatti , S. P. , Everett , M. G. and Freeman , L. C. 1999 . UCINET 5 for Windows. Software for Social Network Analysis. User's Guide , Natick, MA : Analytic Technologies .
  • Boschma , R. A. and Iammarino , S. 2009 . Related variety, trade linkages, and regional growth in Italy . Economic Geography , 85 ( 3 ) : 289 – 311 .
  • Boschma , R. A. and Ter Wal , A. L. J. 2007 . Knowledge networks and innovative performance in an industrial district: The case of a footwear district in the South of Italy . Industry and Innovation , 14 ( 2 ) : 177 – 199 .
  • Brandt , A. , Hahn , C. , Krätke , S. and Kiese , M. 2009 . Metropolitan regions in the knowledge economy: Network analysis as a strategic information tool . Tijdschrift voor Economische en Sociale Geografie , 100 : 236 – 249 .
  • Camagni , R. 1991 . “ Local milieu, uncertainty and innovation networks: Towards a new dynamic theory of economic space ” . In Innovation Networks: Spatial Perspectives , Edited by: Camagni , R. 121 – 142 . London : Belhaven Press .
  • Cantner , U. and Graf , H. 2006 . The network of innovators in Jena: An application of social network analysis . Research Policy , 35 ( 4 ) : 463 – 480 .
  • Coenen , L. , Moodysson , J. , Ryan , C. D. , Asheim , B. T. and Phillips , P. 2006 . Comparing a pharmaceutical and an agro-food bioregion: On the importance of knowledge bases for socio-spatial patterns of innovation . Industry and Innovation , 13 ( 4 ) : 393 – 414 .
  • Cohen , W. M. and Levinthal , D. 1990 . Absorptive capacity: A New perspective on learning and innovation . Administrative Science Quarterly , 35 : 128 – 152 .
  • Cooke , P. 2002 . Biotechnology clusters as regional, sectoral innovation systems . International Regional Science Review , 25 ( 1 ) : 8 – 37 .
  • Cooke , P. 2007 . To construct regional advantage from innovation systems first build policy platforms . European Planning Studies , 15 ( 2 ) : 179 – 194 .
  • Cooke , P. and Morgan , K. 1998 . The Associational Economy: Firms, Regions, and Innovation , Oxford : Oxford University Press .
  • Dohse , D. 2000 . Technology policy and the regions—the case of the BioRegio contest . Research Policy , 29 ( 9 ) : 1111 – 1133 .
  • Eurostat . 2008 . NACE Rev. 2. Statistical Classification of Economic Activities in the European Community , Luxembourg : Eurostat . Available at http://epp.eurostat.ec.europa.eu/cache/ITY_OFFPUB/KS-RA-07-015/EN/KS-RA-07-015-EN.PDF (accessed 13 August 2009)
  • Freeman , L. C. 1979 . Centrality in social networks: Conceptual clarification . Social Networks , 1 ( 3 ) : 215 – 239 .
  • Frenken , K. , Van Oort , F. and Verburg , T. 2007 . Related variety, unrelated variety and regional economic growth . Regional Studies , 41 ( 5 ) : 685 – 697 .
  • Fritsch , M. and Stephan , A. 2005 . Regionalization of innovation policy—introduction to the special issue . Research Policy , 34 ( 8 ) : 1123 – 1127 .
  • Fromhold-Eisebith , M. 2007 . Bridging scales in innovation policies: How to link regional, national and international innovation systems . European Planning Studies , 15 ( 2 ) : 217 – 233 .
  • Fromhold-Eisebith , M. and Eisebith , G. 2005 . How to institutionalize innovative clusters? Comparing explicit top-down and implicit bottom-up approaches . Research Policy , 34 ( 8 ) : 1250 – 1268 .
  • Gertler , M. and Wolfe , D. 2006 . “ Spaces of knowledge flows: Clusters in a global context ” . In Clusters and Regional Development: Critical Reflections and Explorations , Edited by: Asheim , B. , Cooke , P. and Martin , R. 218 – 235 . New York : Routledge .
  • Giuliani , E. and Bell , M. 2005 . The micro-determinants of meso-level learning and innovation: Evidence from a Chilean wine cluster . Research Policy , 34 ( 1 ) : 47 – 68 .
  • Graf , H. 2011 . Gatekeepers in regional networks of innovators . Cambridge Journal of Economics , 35 ( 1 ) : 173 – 198 .
  • Hanneman , R. A. and Riddle , M. 2005 . Introduction to Social Network Methods , Riverside, CA : University of California .
  • Hassink , R. 2005 . How to unlock regional economies from path dependency? From learning region to learning cluster . European Planning Studies , 13 ( 4 ) : 521 – 535 .
  • Hassink , R. and Ibert , O. 2009 . “ Zum Verhältnis von Innovation und Raum in Subnationalen Innovationssystemen ” . In Innovationssysteme: Technologie, Institutionen und die Dynamik der Wettbewerbsfähigkeit , Edited by: Blättel-Mink , B. and Ebner , A. 159 – 175 . Wiesbaden : Verlag für Sozialwissenschaften .
  • Johnson , B. , Lorenz , E. and Lundvall , B.-Å. 2002 . Why all this fuss about codified and tacit knowledge? . Industrial and Corporate Change , 11 ( 2 ) : 245 – 262 .
  • Krätke , S. 2002 . Network analysis of production clusters: The Potsdam, Babelsberg film industry as an example . European Planning Studies , 10 ( 1 ) : 27 – 55 .
  • Krätke , S. 2010 . Regional knowledge networks: A network analysis approach to the interlinking of knowledge resources . European Urban and Regional Studies , 17 ( 1 ) : 83 – 97 .
  • Krätke , S. and Brandt , A. 2009 . Knowledge networks as a regional development resource: A network analysis of the interlinks between scientific institutions and regional firms in the metropolitan region of Hanover, Germany . European Planning Studies , 17 ( 1 ) : 43 – 63 .
  • Laestadius , S. 1998 . “ Technology level, knowledge formation and industrial competence in paper manufacturing ” . In Micro Foundations of Economic Growth , Edited by: Eliasson , G. and Green , C. 212 – 226 . Ann Arbour : The University of Michigan Press .
  • Lundvall , B.-Å. 1992 . National Systems of Innovation: Towards a Theory of Innovation and Interactive Learning , London : Pinter .
  • Malmberg , A. and Maskell , P. 2002 . The elusive concept of localization economies: Towards a knowledge-based theory of spatial clustering . Environment and Planning A , 34 ( 3 ) : 429 – 449 .
  • Moodysson , J. , Coenen , L. and Asheim , B. T. 2008 . Explaining spatial patterns of innovation: Analytical and synthetic modes of knowledge creation in the Medicon Valley life-science cluster . Environment and Planning A , 40 ( 5 ) : 1040 – 1056 .
  • Morgan , K. 1997 . The learning region: Institutions, innovation and regional renewal . Regional Studies , 31 ( 5 ) : 491 – 503 .
  • Morrison , A. 2008 . Gatekeepers of knowledge within industrial districts: Who they are, how they interact . Regional Studies , 42 ( 6 ) : 817 – 835 .
  • Nonaka , I. and Takeuchi , H. 1995 . The Knowledge-creating Company: How Japanese Companies Create the Dynamics of Innovation , New York : Oxford University Press .
  • OECD . 2005 . A Framework for Biotechnology Statistics , Paris : OECD .
  • Owen-Smith , J. and Powell , W. W. 2004 . Knowledge networks as channels and conduits: The effects of spillovers in the Boston biotechnology community . Organization Science , 15 ( 1 ) : 5 – 21 .
  • Polanyi , M. 1966 . The Tacit Dimension , New York : Doubleday .
  • Porter , M. E. 2000 . “ The Oxford handbook of economic geography ” . In The Oxford Handbook of Economic Geography , Edited by: Clark , G. L. , Feldman , M. P. and Gertler , M. S. 253 – 274 . New York : Oxford University Press .
  • Pyke , F. S. , Becattini , G. and Sengenberger , W. 1990 . Industrial Districts and Inter-firm Co-operation in Italy , Geneva : International Institute for Labour Studies .
  • Rehfeld , D. Cluster Management, Sectoral Change and the Context of Structural Policy . Regional growth agendas. Paper presented at the Regional Studies Association Conference, Aalborg University, Aalborg, Denmark ,
  • Scott , J. 2000 . Social Network Analysis: A Handbook , 2 , Thousand Oaks : Sage .
  • Ter Wal , A. L. J. and Boschma , R. A. 2009 . Applying social network analysis in economic geography: Framing some key analytic issues . Annals of Regional Science , 43 ( 3 ) : 739 – 756 .
  • Tödtling , F. and Trippl , M. 2007 . Knowledge links in high-technology industries: Markets, networks or milieu? The case of the Vienna biotechnology cluster . International Journal of Entrepreneurship and Innovation Management , 7 ( 2–5 ) : 345 – 365 .
  • Wasserman , S. and Faust , K. 1994 . Social Network Analysis: Methods and Applications , Cambridge : Cambridge University Press .
  • Waxell , A. and Malmberg , A. 2007 . What is global and what is local in knowledge generating interaction? The case of the biotech cluster in Uppsala, Sweden . Entrepreneurship & Regional Development , 19 ( 2 ) : 137 – 159 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.