Publication Cover
Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 25, 2022 - Issue 12
3,336
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Elevation of brain magnesium with Swiss chard and buckwheat extracts in an animal model of reduced magnesium dietary intake

ORCID Icon, , , , , & show all

References

  • Sadir S, Tabassum S, Emad S, Liaquat L, Batool Z, Madiha S, et al. Neurobehavioral and biochemical effects of magnesium chloride (MgCl2), magnesium sulphate (MgSO4) and magnesium-L-threonate (MgT) supplementation in rats: a dose dependent comparative study. Pak J Pharm Sci. 2019;32:277–283.
  • Slutsky I, Abumaria N, Wu LJ, Huang C, Zhang L, Li B, et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010;65:165–177. doi:10.1016/j.neuron.2009.12.026.
  • Cazzola R, Della Porta M, Manoni M, Iotti S, Pinotti L, Maier JA. Going to the roots of reduced magnesium dietary intake: a tradeoff between climate changes and sources. Heliyon. 2020;6:e05390. doi:10.1016/j.heliyon.2020.e05390.
  • Razzaque MS. Magnesium: are we consuming enough? Nutrients. 2018;10. doi:10.3390/nu10121863.
  • Workinger JL, Doyle RP, Bortz J. Challenges in the diagnosis of magnesium status. Nutrients. 2018;10. doi:10.3390/nu10091202.
  • Moshfegh AG, Ahuja J, Rhodes D, LaComb R. What we eat in America, NHANES 2005-2006: usual nutrient intakes from food and water compared to 1997 dietary reference intakes for vitamin D, calcium, phosphorus, and magneisum. U.S. Department of Agriculture, Agriculture Research Service, Beltsville Human Research Center, Beltsville, MD; 2009.
  • Altura BM. Introduction: importance of Mg in physiology and medicine and the need for ion selective electrodes. Scand J Clin Lab Invest Suppl. 1994;217:5–9.
  • Quann EE, Fulgoni VL, Auestad N. Consuming the daily recommended amounts of dairy products would reduce the prevalence of inadequate micronutrient intakes in the United States: diet modeling study based on NHANES 2007-2010. Nutr J. 2015;14:90. doi:10.1186/s12937-015-0057-5.
  • DiNicolantonio JJ, O'Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018;5:e000668. doi:10.1136/openhrt-2017-000668.
  • Del Gobbo LC, Imamura F, Wu JH, de Oliveira Otto MC, Chiuve SE, Mozaffarian D. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies. Am J Clin Nutr. 2013;98:160–173. doi:10.3945/ajcn.112.053132.
  • Efstratiadis G, Sarigianni M, Gougourelas I. Hypomagnesemia and cardiovascular system. Hippokratia. 2006;10:147–152.
  • Galland L. Magnesium, stress and neuropsychiatric disorders. Magnes Trace Elem. 1991;10:287–301.
  • Glasdam SM, Glasdam S, Peters GH. The importance of magnesium in the human body: a systematic literature review. Adv Clin Chem. 2016;73:169–193. doi:10.1016/bs.acc.2015.10.002.
  • Guasch-Ferré M, Bulló M, Estruch R, Corella D, Martínez-González MA, Ros E, et al. Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk. J Nutr. 2014;144:55–60. doi:10.3945/jn.113.183012.
  • Hruby A, Meigs JB, O'Donnell CJ, Jacques PF, McKeown NM. Higher magnesium intake reduces risk of impaired glucose and insulin metabolism and progression from prediabetes to diabetes in middle-aged Americans. Diabetes Care. 2014;37:419–427. doi:10.2337/dc13-1397.
  • Ikee R. Cardiovascular disease, mortality, and magnesium in chronic kidney disease: growing interest in magnesium-related interventions. Renal Replac Therapy. 2018;4.; doi:10.1186/s41100-017-0142-7.
  • Kirkland AE, Sarlo GL, Holton KF. The role of magnesium in neurological disorders. Nutrients. 2018;10. doi:10.3390/nu10060730.
  • Nayak R, Attry S, Ghosh SN. Serum magnesium as a marker of neurological outcome in severe traumatic brain injury patients. Asian J Neurosurg. 2018;13:685–688. doi:10.4103/ajns.AJNS_232_16.
  • Xue W, You J, Su Y, Wang Q. The effect of magnesium deficiency on neurological disorders: a narrative review article. Iran J Public Health. 2019;48:379–387.
  • Altura BM, Gebrewold A, Zhang A, Altura BT, Gupta RK. Short-term reduction in dietary intake of magnesium causes deficits in brain intracellular free Mg2+ and [H + ]i but not high-energy phosphates as observed by in vivo 31P-NMR. Biochim Biophys Acta. 1997;1358:1–5. doi:10.1016/s0167-4889(97)00077-3.
  • Singewald N, Sinner C, Hetzenauer A, Sartori SB, Murck H. Magnesium-deficient diet alters depression- and anxiety-related behavior in mice–influence of desipramine and Hypericum perforatum extract. Neuropharmacology. 2004;47:1189–1197. doi:10.1016/j.neuropharm.2004.08.010.
  • Morris ME. Brain and CSF magnesium concentrations during magnesium deficit in animals and humans: neurological symptoms. Magnes Res. 1992;5:303–313.
  • Sartori SB, Whittle N, Hetzenauer A, Singewald N. Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment. Neuropharmacology. 2012;62:304–312. doi:10.1016/j.neuropharm.2011.07.027.
  • Haensch C-A. Cerebrospinal fluid magnesium level in different neurological disorders. Neurosci Med. 2010;01:60–63. doi:10.4236/nm.2010.12009.
  • Serita T, Miyahara M, Tanimizu T, Takahashi S, Oishi S, Nagayoshi T, et al. Dietary magnesium deficiency impairs hippocampus-dependent memories without changes in the spine density and morphology of hippocampal neurons in mice. Brain Res Bull. 2019;144:149–157. doi:10.1016/j.brainresbull.2018.11.019.
  • Altura BM, Altura BT. Role of magnesium in patho-physiological processes and the clinical utility of magnesium ion selective electrodes. Scand J Clin Lab Invest Suppl. 1996;224:211–234. doi:10.3109/00365519609088642.
  • Ates M, Kizildag S, Yuksel O, Hosgorler F, Yuce Z, Guvendi G, et al. Dose-dependent absorption profile of different magnesium compounds. Biol Trace Elem Res. 2019;192:244–251. doi:10.1007/s12011-019-01663-0.
  • Kim YJ, McFarlane C, Warner DS, Baker MT, Choi WW, Dexter F. The Effects of plasma and brain magnesium concentrations on lidocaine-induced seizures in the rat. Anesth Analg. 1996;83:1223-8.
  • Vink R. Magnesium in the CNS: recent advances and developments. Magnes Res. 2016;29:95–101. doi:10.1684/mrh.2016.0408.
  • Wary C, Brillault-Salvat C, Bloch G, Leroy-Willig A, Roumenov D, Grognet JM, et al. Effect of chronic magnesium supplementation on magnesium distribution in healthy volunteers evaluated by 31P-NMRS and ion selective electrodes. Br J Clin Pharmacol. 1999;48:655–662. doi:10.1046/j.1365-2125.1999.00063.x.
  • Gee JB, Corbett RJ, Perlman JM, Laptook AR. Hypermagnesemia does not increase brain intracellular magnesium in newborn swine. Pediatr Neurol. 2001;25:304–308. doi:10.1016/s0887-8994(01)00317-4.
  • McKee JA, Brewer RP, Macy GE, Phillips-Bute B, Campbell KA, Borel CO, et al. Analysis of the brain bioavailability of peripherally administered magnesium sulfate: A study in humans with acute brain injury undergoing prolonged induced hypermagnesemia. Crit Care Med. 2005;33:661–666. doi:10.1097/01.ccm.0000156293.35868.b2.
  • Mercieri M, De Blasi RA, Palmisani S, Forte S, Cardelli P, Romano R, et al. Changes in cerebrospinal fluid magnesium levels in patients undergoing spinal anaesthesia for hip arthroplasty: does intravenous infusion of magnesium sulphate make any difference? A prospective, randomized, controlled study. Br J Anaesth. 2012;109:208–215. doi:10.1093/bja/aes146.
  • Karley AJ, White PJ. Moving cationic minerals to edible tissues: potassium, magnesium, calcium. Curr Opin Plant Biol. 2009;12:291–298. doi:10.1016/j.pbi.2009.04.013.
  • White PJ, Broadley MR. Biofortification of crops with seven mineral elements often lacking in human diets–iron, zinc, copper, calcium, magnesium, selenium and iodine. New Phytol. 2009;182:49–84. doi:10.1111/j.1469-8137.2008.02738.x.
  • Wilkinson SR, Welch RM, Mayland HF, Grunes DL. Magnesium in plants: uptake, distribution, function, and utilization by man and animals. Met Ions Biol Syst. 1990;26:33–56.
  • Maathuis FJ. Physiological functions of mineral macronutrients. Curr Opin Plant Biol. 2009;12:250–258. doi:10.1016/j.pbi.2009.04.003.
  • Gout E, Rebeille F, Douce R, Bligny R. Interplay of Mg2+, ADP, and ATP in the cytosol and mitochondria: unravelling the role of Mg2+ in cell respiration. Proc Natl Acad Sci U S A. 2014;111:E4560–4567. doi:10.1073/pnas.1406251111.
  • U.S. Department of Agriculture, Agricultural Research Service. (2018). Nutrient intakes from food and beverages: mean amounts consumed per individual, by gender and age, what we eat in America, NHANES 2015-2016. 2018.
  • Colonna E, Rouphael Y, Barbieri G, De Pascale S. Nutritional quality of ten leafy vegetables harvested at two light intensities. Food Chem. 2016;199:702–710. doi:10.1016/j.foodchem.2015.12.068.
  • Gamba M, Raguindin PF, Asllanaj E, Merlo F, Glisic M, Minder B, et al. Bioactive compounds and nutritional composition of Swiss chard (Beta vulgaris L. var. cicla and flavescens): a systematic review. Crit Rev Food Sci Nutr. 2020: 1–16. doi:10.1080/10408398.2020.1799326.
  • Mzoughi Z, Chahdoura H, Chakroun Y, Camara M, Fernandez-Ruiz V, Morales P, et al. Wild edible Swiss chard leaves (Beta vulgaris L. var. cicla): nutritional, phytochemical composition and biological activities. Food Res Int. 2019;119:612–621. doi:10.1016/j.foodres.2018.10.039.
  • Klepacka J, Najda A, Klimek K. Effect of buckwheat groats processing on the content and bioaccessibility of selected minerals. Foods. 2020;9. doi:10.3390/foods9060832.
  • Huda MN, Lu S, Jahan T, Ding M, Jha R, Zhang K, et al. Treasure from garden: Bioactive compounds of buckwheat. Food Chem. 2021;335:127653. doi:10.1016/j.foodchem.2020.127653.
  • Crinnion WJ. Organic foods contain higher levels of certain nutrients, lower levels of pesticides, and may provide health benefits for the consumer. Altern Med Rev. 2010;15:4–12.
  • Lairon D. Nutritional quality and safety of organic food. Agron. Sustain Dev. 2010;30:33–41. doi:10.1051/agro/2009019.
  • Fine KD, Santa Ana CA, Porter JL, Fordtran JS. Intestinal absorption of magnesium from food and supplements. J Clin Invest. 1991;88:396–402. doi:10.1172/JCI115317.
  • Walf AA, Frye CA. The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nat Protoc. 2007;2:322–328. doi:10.1038/nprot.2007.44.
  • Antunes M, Biala G. The novel object recognition memory: neurobiology, test procedure, and its modifications. Cogn Process. 2012;13:93–110. doi:10.1007/s10339-011-0430-z.
  • Lalonde R. The neurobiological basis of spontaneous alternation. Neurosci Biobehav Rev. 2002;26:91–104. doi:10.1016/s0149-7634(01)00041-0.
  • Newhouse IJ, Johnson KP, Montelpare WJ, McAuliffe JE. Variability within individuals of plasma ionic magnesium concentrations. BMC Physiol. 2002;2:6. doi:10.1186/1472-6793-2-6.
  • Rosanoff A, Weaver CM, Rude RK. Suboptimal magnesium status in the United States: are the health consequences underestimated? Nutr Rev. 2012;70:153–164. doi:10.1111/j.1753-4887.2011.00465.x.
  • Rosanoff A, Dai Q, Shapses SA. Essential nutrient interactions: does low or suboptimal magnesium status interact with vitamin D and/or calcium status? Adv Nutr. 2016;7:25–43. doi:10.3945/an.115.008631.
  • McIntosh TK, Vink R, Yamakami I, Faden AI. Magnesium protects against neurological deficit after brain injury. Brain Res. 1989;482:252–260. doi:10.1016/0006-8993(89)91188-8.
  • Brewer RP, Parra A, Borel CO, Hopkins MB, Reynolds JD. Intravenous magnesium sulfate does not increase ventricular CSF ionized magnesium concentration of patients with intracranial hypertension. Clin Neuropharmacol. 2001;24:341–345. doi:10.1097/00002826-200111000-00005.
  • Chutkow JG. Compendium on magnesium and its role in biology, nutrition, and physiology. In: H Siegel, A Siegel, editors. New York: Marcel Dekker; 1990. p. 441–462.
  • McCarthy J., Kumar R. Divalent cation metabolism: magnesium. In: Schrier RW, editor. The schrier atlas of diseases of the kidney. Hoboken: Wiley-Blackwell; 2000. p. 1–12.
  • Schuette SA, Lashner BA, Janghorbani M. Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection. J Parenter Enteral Nutr. 1994;18:430–435. doi:10.1177/0148607194018005430.
  • Boyle NB, Lawton C, Dye L. The effects of magnesium supplementation on subjective anxiety and stress – a systematic review. Nutrients. 2017;9. doi:10.3390/nu9050429.
  • Pyndt Jorgensen B, Winther G, Kihl P, Nielsen DS, Wegener G, Hansen AK, Sorensen DB. Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice. Acta Neuropsychiatr. 2015;27:307–311. doi:10.1017/neu.2015.10.
  • Grases G, Perez-Castello JA, Sanchis P, Casero A, Perello J, Isern B, et al. Anxiety and stress among science students. Study of calcium and magnesium alterations. Magnes Res. 2006;19:102–106.
  • Laarakker MC, van Lith HA, Ohl F. Behavioral characterization of A/J and C57BL/6J mice using a multidimensional test: association between blood plasma and brain magnesium-ion concentration with anxiety. Physiol Behav. 2011;102:205–219. doi:10.1016/j.physbeh.2010.10.019.
  • Nair AB, Jacob S. A simple practice guide for dose conversion between animals and human. J Basic Clin Pharm. 2016;7:27–31. doi:10.4103/0976-0105.177703.