Antibiotic-Resistant Bacteria: A Challenge for the Food Industry

REFERENCES

• Abriouel , H. , Omar , N. B. , Molinos , A. C. , López , R. L. , Grande , M. J. , Martínez-Viedma , P. , Ortega , E. , Martínez-Cañamero , M. and Galvez , A. 2008 . Comparative analysis of genetic diversity and incidence of virulence factors and antibiotic resistance among enterococcal populations from raw fruit and vegetable foods, water and soil, and clinical samples . Int. J. Food Microbiol. , 123 ( 1–2 ) : 38 – 49 .
   PubMed Web of Science ®Google Scholar
• Aertsen , A. , Van Houdt , R. , Vanoirbeek , K. and Michiels , C. W. 2004 . An SOS response induced by high pressure in Escherichia coli . J. Bacteriol. , 186 ( 18 ) : 6133 – 6141 .
   PubMed Web of Science ®Google Scholar
• AHI (Animal Health Institute) . 2008 . Sales of disease-fighting animal medicines rise . Available at: http://www.ahi.org/files/Media%20Center/Antibiotic%20Use%202007.pdf. Date last accessed: May 4, 2010
   Google Scholar
• Alabouvette , C. , Olivain , C. and Steinberg , C. 2006 . Biological control of plant diseases: The European situation . Eur. J. Plant Pathol. , 114 : 329 – 341 .
   Web of Science ®Google Scholar
• Alanis , A. J. 2005 . Resistance to antibiotics: are we in the post-antibiotic era? . Arch. Med. Res. , 36 ( 6 ) : 697 – 705 .
   PubMed Web of Science ®Google Scholar
• Albihn , A. and Vinnerås , B. 2007 . Biosecurity and arable use of manure and biowaste: Treatment alternatives . Livest. Sci. , 112 ( 3 ) : 232 – 239 .
   Web of Science ®Google Scholar
• Alekshun , M. N. and Levy , S. B. 1997 . Regulation of chromosomally mediated multiple antibiotic resistance: The mar regulon . Antimicrob. Agents Ch. , 41 ( 10 ) : 2067 – 2075 .
   Web of Science ®Google Scholar
• Alonso-Hernando , A. , Capita , R. , Prieto , M. and Alonso-Calleja , C. 2009a . Adaptation and cross-adaptation of Listeria monocytogenes and Salmonella enterica to poultry decontaminants . J. Microbiol. , 47 ( 2 ) : 142 – 146 .
   PubMed Web of Science ®Google Scholar
• Alonso-Hernando , A. , Capita , R. , Prieto , M. and Alonso-Calleja , C. 2009b . Comparison of antibiotic resistance patterns in Listeria monocytogenes and Salmonella enterica strains pre-exposed and exposed to poultry decontaminants . Food Control , 20 ( 12 ) : 1108 – 1111 .
   Web of Science ®Google Scholar
• Alonso-Hernando , A. , Alonso-Calleja , C. and Capita , R. 2009c . Comparative analysis of acid resistance in Listeria monocytogenes and Salmonella enterica strains before and after exposure to poultry decontaminants. Role of the glutamate decarboxylase (GAD) system . Food Microbiol. , 26 ( 8 ) : 905 – 909 .
   PubMed Web of Science ®Google Scholar
• Alonso-Hernando , A. , Alonso-Calleja , C. and Capita , R. 2010 . Effects of exposure to poultry chemical decontaminants on the membrane fluidity of Listeria monocytogenes and Salmonella enterica strains . Int. J. Food Microbiol. , 37 ( 2–3 ) : 130 – 136 .
   Google Scholar
• Álvarez-Ordóñez , A. , Fernández , A. , López , M. , Arenas , R. and Bernardo , A. 2008 . Modifications in membrane fatty acid composition of Salmonella typhymurium in response to growth conditions and their effect on heat resistance . Int. J. Food Microbiol. , 123 ( 3 ) : 212 – 219 .
   PubMed Web of Science ®Google Scholar
• Angulo , F. J. Impacts of antimicrobial growth promoter termination in Denmark. In: Proceedings of the 53rd Western Poultry Disease Conference, pp. 16–19. Sacramento, CA. ,
   Google Scholar
• Armstrong , G. L. , Conn , L. A. and Pinner , R. W. 1999 . Trends in infectious disease mortality in the United States during the 20th Century . JAMA , 281 ( 1 ) : 61 – 66 .
   PubMed Web of Science ®Google Scholar
• Atterbury , R. J. 2009 . Bacteriophage biocontrol in animals and meat products . Microb. Biotechnol. , 2 ( 6 ) : 601 – 612 .
   Google Scholar
• Ausubel , J. H. , Meyer , P. S. and Wernick , I. K. 2001 . Death and the human environment: the United States in the 20th century . Technol. Soc. , 23 ( 3 ) : 131 – 146 .
   Google Scholar
• Bager , F. , Madsen , M. , Christesen , J. and Aarestrup , F. M. 1997 . Avoparcin used as a growth promoter is associated with the occurrence of vancomycin-resistant Enterococcus faecium on Danish poultry and pig farms . Prev. Vet. Med. , 31 ( 1–2 ) : 95 – 112 .
   PubMed Web of Science ®Google Scholar
• Balogh , B. , Jones , J. B. , Iriarte , F. B. and Momol , M. T. 2010 . Phage therapy for plant disease control . Curr. Pharm. Biotechnol. , 11 ( 1 ) : 48 – 57 .
   PubMed Web of Science ®Google Scholar
• Barza , M. and Travers , K. 2002 . Excess infections due to antimicrobial resistance. The “Attributable Fraction.” . Clin. Infect. Dis. , 34 ( Suppl. 3 ) : S126 – S130 .
   PubMed Web of Science ®Google Scholar
• Bax , R. 2001 . How to evaluate and predict the ecological impact of antibiotics: the pharmaceutical industry view from research and development . Clin. Microbiol. Infect. , 7 ( Suppl. 5 ) : 46 – 48 .
   Google Scholar
• Becker , D. , Selbach , M. , Rollenhagen , C. , Ballmaier , M. , Meyer , T. F. , Mann , M. and Bumann , D. 2006 . Robust Salmonella metabolism limits possibilities for new antimicrobials . Nature , 440 ( 7082 ) : 303 – 307 .
   PubMed Web of Science ®Google Scholar
• Beinlich , K. L. , Chuanchuen , R. and Schweizer , H. P. 2001 . Contribution of multidrug efflux pumps to multiple antibiotic resistance in veterinary clinical isolates of Pseudomonas aeruginosa . FEMS Microbiol. Lett. , 198 ( 22 ) : 129 – 134 .
   Google Scholar
• Boeris , P. S. , Domenech , C. E. and Lucchesi , G. I. 2007 . Modification of phospholipid composition in Pseudomonas putida A ATCC 12633 induced by contact with tetradecyltrimethylammonium . J. Appl. Microbiol. , 103 ( 4 ) : 1048 – 1054 .
   Web of Science ®Google Scholar
• Boklund , A. , Alban , L. , Mortensen , S. and Houe , H. 2004 . Biosecurity in 116 Danish fattening swineherds: descriptive results and factor analysis . Prev. Vet. Med. , 66 ( 1–4 ) : 49 – 62 .
   Web of Science ®Google Scholar
• Bremner , A. and Johnston , M. 1996 . “ Control of microbial hazards in poultry processing ” . In Poultry Meat Hygiene and Inspection , 135 – 136 . London : W.B. Saunders .
   Google Scholar
• Bywater , R. J. and Casewell , M. W. 2000 . An assessment of the impact of antibiotic resistance in different bacterial species and of the contribution of animal sources to resistance in human infections . J. Antimicrob. Ch. , 46 ( 4 ) : 643 – 645 .
   Web of Science ®Google Scholar
• Callaway , T. R. , Edrington , T. S. , Anderson , R. C. , Harvey , R. B. , Genovese , K. J. , Kennedy , C. N. , Venn , D. W. and Nisbet , D. J. 2008 . Probiotics, prebiotics and competitive exclusion for prophylaxis against bacterial disease . Anim. Health Res. Rev. , 9 ( 2 ) : 217 – 225 .
   Google Scholar
• Capita , R. 2007 . Variation in Salmonella resistance to poultry chemical decontaminants, based on serotype, phage type, and antibiotic resistance patterns . J. Food Protect. , 70 ( 8 ) : 1835 – 1843 .
   PubMed Web of Science ®Google Scholar
• Capita , R. , Prieto , M. and Alonso-Calleja , C. 2003 . Sampling methods for microbiological analysis of red meat and poultry carcasses . J. Food Protect. , 67 ( 6 ) : 1303 – 1308 .
   Web of Science ®Google Scholar
• Carlson , S. A. , Sharma , V. K. , McCuddin , Z. P. , Rasmussen , M. A. and Franklin , S. K. 2007 . Involvement of an Salmonella genomic island 1 gene in the rumen protozoa-mediated enhancement of invasion for multiple antibiotic resistant Salmonella enterica serovar Typhimurium . Infect. Immun. , 75 ( 2 ) : 792 – 800 .
   Web of Science ®Google Scholar
• Carpenter , C. F. and Chambers , H. F. 2004 . Daptomycin: another novel agent for treating infections due to drug-resistant gram positive pathogens . Clin. Infect. Dis. , 38 ( 7 ) : 994 – 1000 .
   PubMed Web of Science ®Google Scholar
• Cars , O. and Nordberg , O. C. 2004 . “ Antibiotic resistance: The faceless threat ” . In The Global Threat of Antibiotic Resistance: Exploring Roads towards Concerted Action. A Multidisciplinary Meeting at the Dag Hammarskjöld Foundation Uppsala , , Sweden Available at: http://soapimg.icecube.snowfall.se/react/Meeting%20the%20challenge%20of%20Antibiotic%20Resistance%20-%20The%20Swedish%20Experience%20April%202009_version%20with%20chinese%20complements.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• Carvalho , M. G.S. , Steigerwalt , A. G. , Morey , R. E. , Shewmaker , P. L. , Falsen , E. , Facklam , R. R. and Teixeira , L. M. 2008 . Designation of the provisional new enterococcus species CDC PNS-E2 as Enterococcus sanguinicola sp. nov., isolated from human blood, and identification of a strain previously named Enterococcus CDC PNS-E1 as Enterococcus italicus Fortina, Ricci, Mora, and Manachini 2004 . J. Clin. Microbiol. , 46 ( 10 ) : 3473 – 3476 .
   Web of Science ®Google Scholar
• Casewell , M. , Friis , C. , Marco , E. , McMullin , P. and Phillips , I. 2003 . The European ban on growth-promoting antibiotics and emerging consequences for human and animal health . J. Antimicrob. Ch. , 52 ( 2 ) : 159 – 161 .
   PubMed Web of Science ®Google Scholar
• Castanon , J. I.R. 2007 . Review: History of the use of antibiotic as growth promoters in European poultry feeds . Poultry Sci. , 86 : 2466 – 2471 .
   PubMed Web of Science ®Google Scholar
• CDC . 2006 . Management of Multidrug-Resistant Organisms in Healthcare Settings, 2006. Centers for Disease Prevention and Control . Available at: http://www.cdc.gov/ncidod/dhqp/pdf/ar/mdroGuideline2006.pdf. Date last accessed: May 6, 2010.
   Google Scholar
• CDC . 2009 . Centers for Disease Prevention and Control. Antimicrobial Resistance in Healthcare Settings . Available at: http://www.cdc.gov/ncidod/dhqp/ar.html. Date last accessed: May 6, 2010.
   Google Scholar
• Cerf , O. , Carpentier , B. and Sanders , P. 2010 . Tests for determining in-use concentrations of antibiotics and disinfectants are based on entirely different concepts: “Resistance has different meanings.” . Int. J. Food Microbiol. , 136 ( 3 ) : 247 – 254 .
   PubMed Web of Science ®Google Scholar
• Chamba , J. F. and Jamet , E. 2008 . Contribution to the safety assessment of technological microflora found in fermented dairy products . Int. J. Food Microbiol. , 126 ( 3 ) : 263 – 266 .
   Web of Science ®Google Scholar
• Cliver , D. O. 2009 . Disinfection of animal manures, food safety and policy . Biores. Technol. , 100 ( 22 ) : 5392 – 5394 .
   Web of Science ®Google Scholar
• Cloete , T. E. 2003 . Resistance mechanisms of bacteria to antimicrobial compounds . Int. Biodet. Biodegr. , 51 ( 4 ) : 277 – 282 .
   Web of Science ®Google Scholar
• Cole , D. W. , Cole , R. , Gaydos , S. J. , Gray , J. , Hyland , G. , Jacques , M. L. , Powell-Dunford , N. , Sawhney , C. and Au , W. W. 2009 . Aquaculture: Environmental, toxicological, and health issues . Int. J. Hyg. Environ. Health , 212 ( 4 ) : 369 – 377 .
   PubMed Web of Science ®Google Scholar
• Collier , J. and Iheanacho , I. 2002 . The pharmaceutical industry as an informant . Lancet , 360 ( 9343 ) : 1405 – 1409 .
   PubMed Web of Science ®Google Scholar
• Compant , S. , Duffy , B. , Nowak , J. , Clément , C. and Barka , E. A. 2005 . Use of plant growth-promoting bacteria for biocontrol of plant diseases: Principles, mechanisms of action, and future prospects . Appl. Environ. Microbiol. , 71 ( 9 ) : 4951 – 4959 .
   PubMed Web of Science ®Google Scholar
• Companyó , R. , Granados , M. , Guiteras , J. and Prat , M. D. 2009 . Antibiotics in food: Legislation and validation of analytical methodologies . Anal. Bioanal. Chem. , 395 ( 4 ) : 877 – 891 .
   Web of Science ®Google Scholar
• Cools , D. , Merckx , R. , Vlassak , K. and Verhaegen , J. 2001 . Survival of E. coli and Enterococcus spp. derived from pig slurry in soils of different texture . Appl. Soil Ecol. , 17 ( 1 ) : 53 – 62 .
   Google Scholar
• Coque , T. M. , Tomayko , J. F. , Ricke , S. C. , Okhyusen , P. C. and Murray , B. E. 1996 . Vancomycin-resistant enterococci from nosocomial, community, and animal sources in the United States . Antimicrob. Agents Ch. , 40 ( 11 ) : 2605 – 2609 .
   Web of Science ®Google Scholar
• Cosgrove , S. E. , Sakoulas , G. , Perencevich , E. N. , Schwaber , M. J. , Karchmer , A. W. and Carmeli , Y. 2003 . Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteraemia: A meta-analysis . Clin. Infect. Dis. , 36 ( 1 ) : 53 – 59 .
   PubMed Web of Science ®Google Scholar
• Cottell , A. , Denyer , S. , Hanlon , G. , Ochs , D. and Maillard , J. 2009 . Triclosan-tolerant bacteria: Changes in susceptibility to antibiotics . J. Hosp. Infect. , 72 ( 1 ) : 71 – 76 .
   Web of Science ®Google Scholar
• Courvalin , P. and Davies , J. 2003 . Antimicrobials: time to act! . Curr. Opin. Microbiol. , 6 ( 5 ) : 425 – 426 .
   Web of Science ®Google Scholar
• Cox , R. A. , Conquest , C. , Mallaghan , C. and Marples , R. R. 1995 . A major outbreak of methicillin-resistant Staphylococus aureus caused by a new phage type (EMRSA-16) . J. Hosp. Infect. , 29 ( 2 ) : 87 – 106 .
   Web of Science ®Google Scholar
• Daikos , G. L. , Koutsolioutsou , A. , Tsiodras , S. , Theodoridou , M. , Koutouzis , E. I. , Charissiadou , A. , Pangalis , A. , Michos , A. G. , Chaidopoulou , F. , Braoudaki , M. and Syriopoulou , V. P. 2008 . Evolution of macrolide resistance in Streptococcus pneumoniae clinical isolates in the prevaccine era . Diagn. Microbiol. Infect. Dis. , 60 ( 4 ) : 393 – 398 .
   Web of Science ®Google Scholar
• Davidson , P. M. and Zivanovic , S. 2003 . “ The use of natural antimicrobials ” . In Food Preservation Techniques , Edited by: Zeuthen , P. and Bøgh-Sørensen , L. 5 – 30 . Cambridge : Woodhead Publishing Ltd. .
   Google Scholar
• DCosta , V. M. , McGrann , K. M. , Hughes , D. W. and Wright , G. D. 2006 . Sampling the antibiotic resistome . Science , 311 ( 5759 ) : 374 – 377 .
   Web of Science ®Google Scholar
• Demanèche , S. , Sanguin , H. , Poté , J. , Navarro , E. , Bernillon , D. , Mavingui , P. , Wildi , W. , Vogel , T. M. and Simonet , P. 2008 . Antibiotioc-resistant soil bacteria in transgenic plant fields . P. Nat. Acad. Sci. , 105 ( 10 ) : 3957 – 3962 .
   PubMed Web of Science ®Google Scholar
• Demple , B. 1996 . Redox signaling and gene control in the Escherichia coli soxRS oxidative stress regulon: A review . Gene , 179 ( 1 ) : 53 – 57 .
   Web of Science ®Google Scholar
• Dibner , J. J. and Richards , J. D. 2005 . Antibiotic growth promoters in agriculture: history and mode of action . Poultry Sci. , 84 ( 4 ) : 634 – 643 .
   PubMed Web of Science ®Google Scholar
• Dobránszki , J. and Teixeira da Silva , J. A. 2010 . Micropropagation of apple: A review . Biotech. Adv. , 28 ( 4 ) : 462 – 488 .
   Web of Science ®Google Scholar
• Dona , A. and Arvanitoyannis , I. S. 2009 . Health risks of genetically modified foods . Crit. Rev. Food Sci. Nutr. , 49 ( 2 ) : 164 – 175 .
   PubMed Web of Science ®Google Scholar
• Donoghue , D. J. 2003 . Antibiotic residues in poultry tissues and eggs: human health concerns? . Poultry Sci. , 82 ( 4 ) : 618 – 621 .
   PubMed Web of Science ®Google Scholar
• Doublet , B. , Golding , G. R. , Mulvey , M. R. and Cloeckaert , A. 2008 . Secondary chromosomal attachment site and tandem integration of the mobilizable Salmonella genomic island 1 . PLoS ONE , 3 ( 4 ) : 1 – 11 . Available at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2297512/pdf/pone.0002060.pdf. Date last accessed: May 6, 2010.
   Google Scholar
• Doyle , M. P. and Erickson , M. C. 2006 . Emerging microbiological food safety issues related to meat . Meat Sci. , 74 ( 1 ) : 98 – 112 .
   Web of Science ®Google Scholar
• Duggan , P. S. , Chambers , P. A. , Heritage , J. and Forbes , J. M. 2000 . Survival of free DNA encoding antibiotic resistance from transgenic maize and the transformation activity of DNA on ovine saliva, ovine rumen fluid and silage effluent . FEMS Microbiol. Lett. , 191 ( 1 ) : 71 – 77 .
   Web of Science ®Google Scholar
• EARSS . 2005 . European Antimicrobial Resistance Surveillance System. Annual Report 2005 . Available at: http://www.rivm.nl/earss/result/Monitoring_reports/. Date last accessed: May 6, 2010.
   Google Scholar
• EARSS . 2007 . European Antimicrobial Resistance Surveillance System. Annual report 2007. European Antibiotic Resistance Surveillance System . Available at: http://www.rivm.nl/earss/Images/EARSS%202007_FINAL_tcm61-55933.pdf. Data last accessed: May 6, 2010.
   Google Scholar
• EASAC . 2007 . Tackling antibacterial resistance in Europe. European Academies Science Advisory Council, June 2007 . Available at: http://www.leopoldina-halle.de/easac-report07.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• ECDC/EFSA/EMEA . 2009 . Joint scientific report of ECDC, EFSA and EMEA on methicillin resistant Staphylococcus aureus (MRSA) in livestock, companion animals and foods. EFSA-Q-2009–00612 (EFSA Scientific Report 2009 301, 1–10) and EMEA/CVMP/SAGAM/62464/2009 . Available at: http://www.efsa.europa.eu/de/scdocs/doc/301r.pdf. Date last accessed: July 12, 2010.
   Google Scholar
• ECDC/EFSA/EMEA/SCENIHR . 2009 . Joint Opinion on antimicrobial resistance (AMR) focused on zoonotic infections. Scientific Opinion of the European Centre for Disease Prevention and Control; Scientific Opinion of the Panel on Biological Hazards; Opinion of the Committee for Medicinal Products for Veterinary Use; Scientific Opinion of the Scientific Committee on Emerging and Newly Identified Health Risks . EFSA J. , 7 ( 11 ) : 1372 – 1450 . 2009 Available at: http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/1372.pdf?ssbinary=true. Date last accessed: May 6, 2010.
   Google Scholar
• ECDC/EMEA . 2009 . ECDC/EMEA (European Centre for Disease Prevention and Control/European Medicines Agency) joint technical report. The bacterial challenge: time to react . Available at: http://ecdc.europa.eu/en/publications/Publications/0909_TER_The_Bacterial_Challenge_Time_to_React.pdf. Date last accessed: May 6, 2010.
   Google Scholar
• Economic and Social Committee of the European Union . 1998 . Opinion on resistance to antibiotics as a threat to public health. Brussels, Septembre 1998. N° ESC-98–016-EN . Available at : http://eescopinions.eesc.europa.eu/EESCopinionDocument.aspx?identifier=ces\anciennes_sections\envi\envi471\ces1118-1998_ac.doc&language=EN. Date last accessed: May 6, 2010.
   Google Scholar
• Edmond , M. B. , Ober , J. F. , Dawson , J. D. , Weinbaum , D. L. and Wenzel , R. P. 1996 . Vancomycin-resistant enterococcal bacteremia: natural history and attributable mortality . Clin. Infect. Dis. , 23 ( 6 ) : 1234 – 1239 .
   PubMed Web of Science ®Google Scholar
• EEA (European Environment Agency) . 2010 . Environmental Terminology and Discovery Service (ETDS). Definitions . Available at: http://glossary.eea.europa.eu/terminology/concept_html?term=fungicide. Date last accessed: May 6, 2010.
   Google Scholar
• EFSA . 2004 . Opinion of the Scientific Panel on Genetically Modified Organisms on the use of antibiotic resistance genes as marker genes in genetically modified plants . EFSA J. , 48 : 1 – 18 . 2004 Available at: http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/opinion_gmo_05_en1,2.pdf. Date last accessed: July 17, 2010.
   Google Scholar
• EFSA . 2006a . Guidance document of the Scientific Panel of Genetically Modified Organisms for the risk assessment of genetically modified plants and derived food and feed. European Food Safety Authority . EFSA J. , 99 : 1 – 100 . 2006 Available at: http://www.efsa.europa.eu/cs/BlobServer/Guidance_of_Panel/gmo_guidance_derived_feed_food,0.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2006b . Guidance document of the scientific panel on genetically modified organisms for the risk assessment of genetically modified microorganisms and their derived products intended for food and feed use . EFSA J. , 374 : 1 – 115 . 2006 Available at: http://www.efsa.europa.eu/cs/BlobServer/Guidance_of_Panel/comm_Guidance_gmo_en.pdf?ssbinary= true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2007a . The Community Summary Report on Trends and Sources of Zoonoses, Zoonotic Agents, Antimicrobial Resistance and Foodborne Outbreaks in the European Union in 2006 . EFSA J. , 130 : 2 – 352 . 2007 Available at: http://www.efsa.europa.eu/en/scdocs/doc/130r.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2007b . Statement of the Scientific Panel on Genetically Modified Organisms on the safe use of the nptII antibiotic resistance marker gene in genetically modified plants . Available at: http://www.efsa.europa.eu/cs/BlobServer/Statement/gmo_statement_nptII_.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2007c . Opinion of the Scientific Committee on a request from EFSA on the introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA . EFSA J. , 587 : 1 – 16 . 2007 http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/sc_op_ej587_qps_en,3.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2007d . Opinion of the Scientific Panel on Biological Hazards on the safety vis-à-vis biological risk of the mesophilic process of biogas and compost treatment of animal by-products . EFSA J. , 465 : 1 – 16 . 2007 http://www.efsa.europa.eu/en/scdocs/doc/465.pdf. Date last accessed: July 17, 2010.
   Google Scholar
• EFSA . 2008a . Scientific opinion of the panel on biological hazards on a request from the European Food Safety Authority on foodborne antimicrobial resistance as a biological hazard . EFSA J. , 765 : 1 – 87 . 2008 Available at: http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/biohaz_op_ej765_antimicrobial_resistance_en,3.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2008b . Scientific Opinion of the Panel on Biological Hazards on a request from DG SANCO on the assessment of the possible effect of the four antimicrobial treatment substances on the emergence of antimicrobial resistance . EFSA J. , 659 : 1 – 26 . 2008 Available at: http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/biohaz_op_ej659_decontamination_four_substances_en,3.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2008c . Technical guidance prepared by the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) on the update of the criteria used in the assessment of bacterial resistance to antibiotics of human or veterinary importance. Adopted on 18 June, 2008 . EFSA J. , 732 : 1 – 15 . 2008 Available at: http://www.efsa.europa.eu/cs/BlobServer/Guidance_of_Panel/feedap_op_ej732_tg_antimicrobial_resistance_en,0.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2008d . Scientific Opinion of the Panel on Biological Hazards on a request from EFSA on the maintenance of the QPS list of microorganisms intentionally added to food or feed. Adopted on 10 December 2008 . EFSA J. , 923 : 1 – 48 . 2008 Available at: http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/biohaz_op_ej923_qps_en.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2008e . Scientific Opinion of the Panel on Biological Hazards on a request from the Health and Consumer Protection, Directorate General, European Commission on Microbiological Risk Assessment in feedingstuffs for food-producing animals. Adopted on 5 June 2008 . EFSA J. , 720 : 1 – 84 . 2008 Available at: http://www.efsa.europa.eu/en/scdocs/doc/720.pdf. Date last accessed: July 6, 2010.
   Google Scholar
• EFSA . 2009a . Scientific Opinion of the Panel on Biological Hazards on a request from the European Commission on Assessment of the Public Health significance of methicillin resistant Staphylococcus aureus (MRSA) in animals and foods . EFSA J. , 993 : 1 – 73 . 2009 Available at: http://www.efsa.europa.eu/cs/BlobServer/Scientific_Opinion/biohaz_op_993_mrsa_en,3.pdf?ssbinary=true. Date last accessed: May 6, 2010.
   Google Scholar
• EFSA . 2009b . Reasoned opinion of EFSA prepared by the Pesticides Unit (PRAPeR) on the 2007 Annual Report on Pesticide Residues . EFSA Scientific Report , 305 : 1 – 106 . 2009 Available at: http://www.efsa.europa.eu/cs/BlobServer/Report/EFSA_2007_Annual_Report_Pesticide%20Residue_en.pdf?ssbinary=true. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2009c . Consolidated presentation of the joint Scientific Opinion of the GMO and BIOHAZ Panels on the “Use of Antibiotic Resistance Genes as Marker Genes in Genetically Modified Plants” and the Scientific Opinion of the GMO Panel on “Consequences of the Opinion on the Use of Antibiotic Resistance Genes as Marker Genes in Genetically Modified Plants on Previous EFSA Assessments of Individual GM Plants.” . EFSA J. , 1108 : 1 – 8 . 2009 Available at: http://www.efsa.europa.eu/en/scdocs/doc/1108.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2010a . The community summary report on Trends and Sources of Zoonoses and Zoonotic Agents and Food-borne Outbreaks in the European Union in 2008 . EFSA J. , 8 ( 1 ) : 1496 – 1863 . 2010 Available at: http://www.efsa.europa.eu/en/scdocs/doc/1496.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• EFSA . 2010b . EFSA Panel on Biological Hazards (BIOHAZ) Guidance on Revision of the joint AFC/BIOHAZ guidance document on the submission of data for the evaluation of the safety and efficacy of substances for the removal of microbial surface contamination of foods of animal origin intended for human consumption . EFSA J , 8 ( 4 ) : 1544 – 1575 . 2010 Available at: http://www.efsa.europa.eu/en/scdocs/doc/1544.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• Einarsson , S. , Kristjansson , M. , Kristinsson , K. G. , Kjartansson , G. and Jonsson , S. 1998 . Pneumonia caused by Penicillin-non-susceptible and Penicillin-susceptible Pneumococci in adults: A case-control study . Scand. J. Infect. Dis. , 30 ( 3 ) : 253 – 256 .
   Web of Science ®Google Scholar
• Erill , I. , Campoy , S. and Barbé , J. 2007 . Aeons of distress: an evolutionary perspective on the bacterial SOS response . FEMS Microbiol. Rev. , 31 ( 6 ) : 637 – 656 .
   PubMed Web of Science ®Google Scholar
• European Commission . 1999 . Opinion of the Scientific Steering Committee on Antimicrobial Resistance. 28 May 1999 . Available at: http://ec.europa.eu/food/fs/sc/ssc/out50_en.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2001a . Communication from the Commission on a Community Strategy against antimicrobial resistance /* COM/2001/0333 final Volume I. . Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:52001DC0333:EN:HTML. Date last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2001b . Opinion of the Scientific Committee on Animal Nutrition on the criteria for assessing the safety of micro-organisms resistant to antibiotics of human clinical and veterinary importance, adopted on 3 July 2001, revised on 24 January 2003 . Available at: http://ec.europa.eu/food/fs/sc/scan/out108_en.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2006a . International surveillance network for the enteric infections - Salmonella, VTEC O157 and Campylobacter. Enter-net – Human enteric pathogen dedicated surveillance network Final report for the period 01/10/2003 – 01/10/2006 . Available at: http://ec.europa.eu/health/ph_projects/2003/action2/docs/2003_2_20_frep.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2006b . Scientific Committee on consumer products (SCCP). Opinion on triclosan. SCCP/1040/06. Adopted by the SCCP during the 9th plenary meeting of 10 October 2006 . Available at: http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_073.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2008 . Commission staff working document on the implementation of national residue monitoring Plans in the member states in 2007 (Council Directive 96/23/EC) . Available at: http://ec.europa.eu/food/food/chemicalsafety/residues/workdoc_2007_en.pdf. Data last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2009a . The Rapid Alert System for Food and Feed (RASFF). Annual Report 2008. EU Directorate General for Health and Consumers, Luxemburg . Available at: http://ec.europa.eu/food/food/rapidalert/report2008_en.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• European Commission . 2009b . EU pesticides database . Available at: http://ec.europa.eu/sanco_pesticides/public/index.cfm. Date last accessed: May 7, 2010.
   Google Scholar
• European Parliament . 2006 . Antibiotic resistance. IP/A/STOA/ST/2006-4 . Available at: http://www.europarl.europa.eu/stoa/publications/studies/stoa173_en.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• FAO/WHO . 1999 . Codex Alimentarius. Food Hygiene Basic Texts, 2nd ed. , Rome : Joint FAO/WHO Food Standards Programme. Codex Alimentarius Commission . Available at: ftp://ftp.fao.org/docrep/fao/005/Y1579e/Y1579e.pdf. Date last accessed: July 12, 2010.
   Google Scholar
• Flensburg , J. and Sköld , O. 1984 . Regulatory changes in the formation of chromosomal dihydrofolate reductase causing resistance to trimethoprim . J. Bacteriol. , 159 ( 1 ) : 184 – 190 .
   Web of Science ®Google Scholar
• Fortina , M. G. , Ricci , G. , Borgo , F. , Manachini , P. L. , Arends , K. , Schiwon , K. , Abajy , M. Y. and Grohmann , E. 2008 . A survey on biotechnological potential and safety of the novel Enterococcus species of dairy origin, E. italicus . Int. J. Food Microbiol. , 123 ( 3 ) : 204 – 211 .
   Web of Science ®Google Scholar
• FVE . 2002 . Antibiotic resistance and prudent use of antibiotics in veterinary medicine. Federation of Veterinarians of Europe, Brussels . Available at: http://www.fve.org/news/publications/pdf/antibioen.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• Gaggìa , F. , Mattarelli , P. and Biavati , B. 2010 . Probiotics and prebiotics in animal feeding for safe food production . Int. J. Food Microbiol. , 141 ( Suppl. 1 ) : S15 – S28 .
   Google Scholar
• Garcia-Armisen , T. and Servais , P. 2007 . Respective contributions of point and non-point sources of E. coli and enterococci in a large urbanized watershed (the Seine river, France) . J. Environ. Man. , 82 ( 4 ) : 512 – 518 .
   Web of Science ®Google Scholar
• Gay , P. and Guillespie , S. H. 2005 . Review. Antibiotic resistance markers in genetically modified plants: a risk to human health? . Lancet Infect. Dis. , 5 ( 10 ) : 637 – 646 .
   PubMed Web of Science ®Google Scholar
• Gebhard , F. and Smalla , K. 1998 . Transformation of Acinetobacter sp. strain BD413 by transgenic sugar beet DNA . Appl. Environ. Microbiol. , 64 ( 4 ) : 1550 – 1554 .
   Web of Science ®Google Scholar
• Gibbs , R. A. , Hu , H. J. , Ho , G. E. and Unkovich , I. 1997 . Regrowth of faecal coliforms and salmonellae in stored biosolids and soil amended with biocides . Water Sci. Technol. , 35 ( 11–12 ) : 269 – 275 .
   Web of Science ®Google Scholar
• Gomes , B. C. , Esteves , C. T. , Palazzo , I. C.V. , Darini , A. L.C. , Felis , G. E. , Sechi , L. A. , Franco , B. D.G.M. and De Martinis , E. C.P. 2008 . Prevalence and characterization of Enterococcus spp. isolated from Brazilian foods . Food Microbiol. , 25 ( 5 ) : 668 – 675 .
   Web of Science ®Google Scholar
• Gómez-Escalada , M. , Harwood , J. L. , Maillard , J.-Y. and Ochs , D. 2005 . Triclosan inhibition of fatty acid synthesis and its effect on growth of E. coli and Ps. aeruginosa . J. Antimicrob. Ch. , 55 ( 6 ) : 879 – 882 .
   Web of Science ®Google Scholar
• Gradel , K. O. , Randall , L. , Sayers , A. R. and Davies , R. H. 2005 . Possible associations between Salmonella persistence in poultry houses and resistance to commonly used disinfectants and a putative role of mar. . Vet. Microbiol. , 107 ( 1–2 ) : 127 – 138 .
   PubMed Web of Science ®Google Scholar
• Graham , J. P. , Price , L. B. , Evans , S. L. , Graczyk , T. K. and Silbergeld , E. K. 2009 . Antibiotic resistant enterococci and staphylococci isolated from flies collected near confined poultry feeding operations . Sci. Total Environ. , 407 ( 8 ) : 2701 – 2710 .
   PubMed Web of Science ®Google Scholar
• Grave , K. , Jersen , V. F. , Odensvik , K. , Wierup , M. and Bangen , M. 2006 . Usage of veterinary therapeutic antimicrobials in Denmark, Norway and Sweden following termination of antimicrobial growth promoter use . Prev. Vet. Med. , 75 ( 1–2 ) : 123 – 132 .
   PubMed Web of Science ®Google Scholar
• Guerin , E. , Cambray , G. , Sánchez-Alberola , N. , Campoy , S. , Erill , I. , Da Re , S. , González-Zorn , B. , Barbé , J. , Ploy , M-C. and Mazel , D. 2009 . The SOS response controls integron recombination . Science , 324 ( 5930 ) : 1034
   PubMed Web of Science ®Google Scholar
• Hald , T. , Wong , D. M.L.F. and Aarestrup , F. M. 2007 . The attribution of human infections with antimicrobial resistant Salmonella bacteria in Denmark to sources of animal origin . Foodborne Path. Dis. , 4 ( 3 ) : 313 – 326 .
   PubMed Web of Science ®Google Scholar
• Hall-Stoodley , L. , Costerton , J. W. and Stoodley , P. 2004 . Bacterial biofilms: from the natural environment to infectious diseases . Nature Rev. Microbiol. , 2 ( 2 ) : 95 – 108 .
   PubMed Web of Science ®Google Scholar
• Hammerum , A. M. , Heuer , O. E. , Lester , C. H. , Agersø , Y. , Seyfarth , A. M. , Emborg , H. D. , Frimodt-Møller , N. and Monnet , D. L. 2007 . Comment on: withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health . Int. J. Antimicrob. Ag. , 30 ( 5 ) : 466 – 468 .
   PubMed Web of Science ®Google Scholar
• Heinonen , M. , Laurila , T. , Vidgren , G. and Levonen , K. 2011 . Eradication of Mycoplasma hyopneumoniae from a swine finishing herd without total depopulation . Vet. J. , 188 ( 1 ) : 110 – 114 .
   Web of Science ®Google Scholar
• Helms , M. , Simonsen , J. and Mølbak , K. 2004 . Quinolone resistance is associated with increased risk of invasive illness or death during infection with Salmonella serotype Typhimurium . J. Infect. Dis. , 190 ( 9 ) : 1652 – 1654 .
   PubMed Web of Science ®Google Scholar
• Helms , M. , Simonsen , J. , Olsen , K. E. and Mølbak , K. 2005 . Adverse health events associated with antimicrobial drug resistance in Campylobacter species: A registry-based cohort study . J. Infect. Dis. , 191 ( 7 ) : 1050 – 1055 .
   PubMed Web of Science ®Google Scholar
• Hof , H. 2001 . Critical annotations to the use of azole antifungals for plant protection . Antimicrob. Agents Ch. , 45 ( 11 ) : 2987 – 2990 .
   Web of Science ®Google Scholar
• Høiby , N. , Bjarnsholt , T. , Givskov , M. , Molin , S. and Ciofu , O. 2010 . Antibiotic resistance of bacterial biofilms . Int. J. Antimicrob. Ag. , 35 ( 4 ) : 322 – 332 .
   PubMed Web of Science ®Google Scholar
• Holmberg , S. D. , Osterholm , M. T. , Senger , K. A. and Cohen , M. L. 1984 . Drug-resistant Salmonella from animals fed antimicrobials . New England J. Med. , 311 ( 10 ) : 617 – 622 .
   PubMed Web of Science ®Google Scholar
• HPA . 2008 . Antimicrobial Resistance and Prescribing in England, Wales and Northern Ireland , London : Health Protection Agency . 2008 Available at: http://www.hpa.org.uk/web/HPAwebFile/HPAweb_C/1216798080469. Date last accessed: May 7, 2010.
   Google Scholar
• Hunter , P. R. , Wilkinson , D. C. , Catling , L. A. and Barker , G. C. 2008 . Meta-analysis of experimental data concerning antimicrobial resistance gene transfer rates during conjugation . Appl. Environ. Microbiol. , 74 ( 19 ) : 6085 – 6090 .
   Web of Science ®Google Scholar
• Hutchison , M. L. , Walters , L. D. , Moore , A. and Avery , S. M. 2005 . Declines of zoonotic agents in liquid livestock wastes stored in batches on-farm . J. Appl. Microbiol. , 99 ( 1 ) : 58 – 65 .
   Web of Science ®Google Scholar
• Huyghebaert , G. , Ducatelle , R. and Van Immerseel , F. V. 2011 . An update on alternatives to antimicrobial growth promoters for broilers . Vet. J. , 187 ( 2 ) : 182 – 188 .
   PubMed Web of Science ®Google Scholar
• IFT (Institute of Food Technologists) . 2006 . Antimicrobial resistance: Implications for the Food System . Compr. Rev. Food Sci. Food Safety , 5 ( 3 ) : 71 – 137 .
   Web of Science ®Google Scholar
• James , C. 2008 . Global status of commercialized Biotech/GM Crops. International Service for the Acquisition of Agri-biotech Applications Brief No 39. ISAAA, Ithaca, N.Y. . Available at: http://croplife.intraspin.com/Biotech/papers/ID_372_james.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• Jansen , W. T. , van der Bruggen , J. T. , Verhoef , J. and Fluit , A. C. 2006 . Bacterial resistance: a sensitive issue complexity of the challenge and containment strategy in Europe . Drug Resist. Update , 9 ( 3 ) : 123 – 133 .
   Web of Science ®Google Scholar
• Jensen , L. B. , Agerso , Y. and Senelov , G. 2002 . Presence of erm genes among macrolide-resistant Gram-positive bacteria isolated from Danish farm soil . Environ. Int. , 28 ( 6 ) : 487 – 491 .
   Web of Science ®Google Scholar
• Joerger , R. D. 2002 . Alternatives to antibiotics: bacteriocins, antimicrobial peptides and bacteriphages . Poultry Sci. , 82 ( 4 ) : 640 – 647 .
   Web of Science ®Google Scholar
• Jolivet-Gougeon , A. , David-Jobert , S. , Tamanai-Shacoori , Z. , Menard , C. and Cormier , M. 2000 . Osmotic stress-induced genetic rearrangements in Escherichia coli H10407 detected by randomly amplified polymorphic DNA analysis . Appl. Environ. Microbiol. , 66 ( 12 ) : 5484 – 5487 .
   Web of Science ®Google Scholar
• Jurgens , D. J. , Sattar , S. A. and Mah , T. F. 2008 . Chloraminated drinking water does not generate bacterial resistance to antibiotics in Pseudomonas aeruginosa biofilms . Lett. Appl. Microbiol. , 46 ( 5 ) : 562 – 567 .
   Web of Science ®Google Scholar
• Katzif , S. , Danavall , D. , Bowers , S. , Balthazar , J. T. and Shafer , W. M. 2003 . The major cold shock gene cspA, is involved in the susceptibility of Staphylococcus aureus to an antimicrobial peptide of human cathepsin G . Infect. Immun. , 71 ( 8 ) : 4304 – 4312 .
   Web of Science ®Google Scholar
• Kay , E. , Vogel , T. M. , Bertolla , F. , Nalin , R. and Simonet , P. 2002 . In situ transfer of antibiotic resistance genes from transgenic (transplastomic) tobacco plants to bacteria . Appl. Environ. Microbiol. , 68 ( 7 ) : 3345 – 3351 .
   Web of Science ®Google Scholar
• Keese , P. 2008 . Risks from GMOs due to horizontal gene transfer . Environ Biosafety Res. , 7 ( 3 ) : 123 – 149 .
   PubMedGoogle Scholar
• Kempf , I. and Zeitouni , S. 2012 . Coût biologique de la résistance aux antibiotiques: analyse et conséquences . Pathol. Biol. , 60 ( 2 ) : e9 – e14 .
   Google Scholar
• Kim , H. , Ryu , J. H. and Beuchat , L. R. 2007 . Effectiveness of disinfectants in killing Enterobacter sakazakii in suspension, dried on the surface of stainless steel, and in a biofilm . Appl. Environ. Microbiol. , 73 ( 4 ) : 1256 – 1265 .
   Web of Science ®Google Scholar
• Kim , S. and Aga , D. S. 2007 . Potential ecological and human health impacts of antibiotics and antibiotic-resistant bacteria from wastewater treatment plants . J. Toxicol. Environ. Health B. , 10 : 559 – 573 .
   PubMed Web of Science ®Google Scholar
• Klein , G. , Pack , A. and Reuter , G. 1998 . Antibiotic resistance patterns of enterococci and occurrence of vancomycin-resistant enterococci in raw minced beef and pork in Germany . Appl. Environ. Microbiol. , 64 ( 5 ) : 1825 – 1830 .
   Web of Science ®Google Scholar
• Kollef , M. H. , Sherman , G. , Ward , S. and Fraser , V. J. 1999 . Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients . Chest. , 115 ( 2 ) : 462 – 474 .
   PubMed Web of Science ®Google Scholar
• Kools , S. A. , Moltmann , J. F. and Knacker , T. 2008 . Estimating the use of veterinary medicines in the European Union . Regul. Toxicol. Pharm. , 50 ( 1 ) : 59 – 65 .
   PubMed Web of Science ®Google Scholar
• Kreling , D. H. , Mott , D. A. , Wiederholt , J. B. , Lundy , J. and Levitt , L. 2001 . Prescription Drug Trends: A Chartbook Update Menlo Park , CA The Henry J. Kaiser Family Foundation
   Google Scholar
• Kudva , I. T. , Blanch , K. and Hovde , C. J. 1998 . Analysis of Escherichia coli O157:H7 survival in ovine or bovine manure and manure slurry . Appl. Environ. Microbiol. , 64 ( 9 ) : 3166 – 3174 .
   PubMed Web of Science ®Google Scholar
• Kümmerer , K. , Al-Ahmad , A. and Mersch-Sundermann , V. 2000 . Biodegradability of some antibiotics, elimination of the genotoxicity and affection of wastewater bacteria in a simple test . Chemosph. , 40 ( 7 ) : 701 – 710 .
   PubMed Web of Science ®Google Scholar
• Kümmerle , N. , Feucht , H.-H. and Kaulfers , P.-M. 1996 . Plasmid-mediated formaldehyde resistance in Escherichia coli: characterization of resistance gene . Antimicrob. Agents Ch. , 40 ( 10 ) : 2276 – 2279 .
   PubMed Web of Science ®Google Scholar
• Lado , B. H. and Yousef , A. E. 2002 . Alternative food-preservation technologies: efficacy and mechanisms . Microbes Infect. , 4 ( 4 ) : 433 – 440 .
   PubMed Web of Science ®Google Scholar
• Lamers , J. , Wanten , P. and Blok , W. 2004 . Biological soil disinfestation: a safe and effective approach for controlling soilborne pests and diseases . Agroindustria , 2004 ( 3 ) : 289 – 291 .
   Google Scholar
• Ledder , R. G. , Gilbert , P. , Wilis , C. and McBain , A. J. 2006 . Effects of chronic triclosan exposure upon the antimicrobial susceptibility of 40 ex-situ environmental and human isolates . J. Apl. Microbiol. , 100 ( 5 ) : 1132 – 1140 .
   Web of Science ®Google Scholar
• Lee , Y. K. 2009 . “ Probiotic microorganisms ” . In Handbook of probiotics and prebiotics, 2nd ed. , Edited by: Lee , Y. K. and Salminen , S. New York : John Wiley and Sons, Inc. . Available at: http://media.wiley.com/product_data/excerpt/41/04701354/0470135441.pdf. Date last accessed: May 6, 2010.
   Google Scholar
• Lester , C. H. , Frimodt-Møller , N. , Sørensen , T. L. , Monnet , D. L. and Hammerum , A. M. 2006 . In vivo transfer of the vanA resistance gene from an isolate of animal origin to an Enterococcus faecium isolate of human origin in the intestines of human volunteers . Antimicrob. Agents Ch. , 50 ( 2 ) : 596 – 599 .
   Web of Science ®Google Scholar
• Lewis , K. 2008 . Multidrug tolerance of biofilms and persister cells . Current Top. Microbiol. Immunol. , 322 : 107 – 131 .
   PubMed Web of Science ®Google Scholar
• Li , D. , Yu , T. , Zhang , Y. , Yang , M. , Li , Z. , Liu , M. and Qi , R. 2010 . Antibiotic resistance characteristics of environmental bacteria oxytetracycline production wastewater treatment plant and the receiving river . Appl. Environ. Microbiol. , 76 ( 11 ) : 3444 – 3451 .
   PubMed Web of Science ®Google Scholar
• Lin , C.-Y. 2003 . Improving plant protection for the development of sustainable agriculture in Taiwan . Micronesica , 7 : 101 – 112 . Suppl.
   Google Scholar
• Liu , J. , Liu , X. , Dai , L. and Wang , G. 2007 . Recent progress in elucidating the structure, function and evolution of disease resistance genes in plants . J. Genet. Genomics , 34 ( 9 ) : 765 – 776 .
   PubMedGoogle Scholar
• Loftin , K. A. , Henny , C. , Adams , C. D. , Surampali , R. and Mormile , M. R. 2005 . Inhibition of microbial metabolism in anaerobic lagoons by selected sulfonamides, tetracyclines, lincomycin and tylosin tartrate . Environ. Toxicol. Chem. , 24 ( 4 ) : 782 – 788 .
   Web of Science ®Google Scholar
• Lunestad , B. T. , Nesse , L. , Lassen , J. , Svihus , B. , Nesbakken , T. , Fossum , K. , Rosnes , J. T. , Kruse , H. and Yazdankhah , S. 2007 . Salmonella in fish feed; occurrence and implications for fish and human health in Norway . Aquaculture , 265 ( 1–4 ) : 1 – 8 .
   Web of Science ®Google Scholar
• Ma , D. , Cook , D. N. , Alberti , M. , Pon , N. G. , Nikaido , H. and Hearst , J. E. 1995 . Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli . Mol. Microbiol. , 16 ( 1 ) : 45 – 55 .
   PubMed Web of Science ®Google Scholar
• Mah , T.-F.C. and O’Toole , G. A. 2001 . Review. Mechanisms of biofilm resistance to antimicrobial agents . Trends Microbiol. , 9 ( 1 ) : 34 – 39 .
   PubMed Web of Science ®Google Scholar
• McEwen , S. A. 2006 . Antibiotic use in animal agriculture: What have we learned and where are we going? . Anim. Biotechnol. , 17 ( 2 ) : 239 – 250 .
   PubMed Web of Science ®Google Scholar
• McGowan-Spicer , L. L. , Fedorka-Cray , P. J. , Frye , J. G. , Meinersmann , R. J. , Barret , J. B. and Jackson , C. R. 2008 . Antimicrobial resistance and virulence of Enterococcus faecalis isolated from retail food . J. Food Protect. , 71 ( 4 ) : 760 – 769 .
   Web of Science ®Google Scholar
• McMahon , M. A.S. , Bair , I. S. , Moore , J. E. and McDowell , D. A. 2007 . The rate of horizontal transmission of antibiotic resistance plasmids is increased in food preservation-stressed bacteria . J. Appl. Microbiol. , 103 ( 5 ) : 1883 – 1888 .
   Web of Science ®Google Scholar
• McManus , P. S. 2000 . Antibiotic use and microbial resistance in plant agriculture . ASM News , 66 ( 8 ) : 448 – 449 .
   Google Scholar
• McManus , P. S. , Stockwell , V. O. , Sundin , G. W. and Jones , A. L. 2002 . Antibiotic use in plant agriculture . Annual Rev. Phytopathol. , 40 : 443 – 465 .
   PubMed Web of Science ®Google Scholar
• Meeusen , E. N.T. , Walker , J. , Peters , A. , Pastoret , P.-P. and Jurgersen , G. 2007 . Current status of veterinary vaccines . Clin. Microbiol. Rev. , 20 ( 3 ) : 489 – 510 .
   PubMed Web of Science ®Google Scholar
• Miller , G. Y. , McNamara , P. E. and Singer , R. S. 2006 . Stakeholder position paper: Economist's perspectives on antibiotic use in animals . Prev. Vet. Med. , 73 ( 2–3 ) : 163 – 168 .
   Web of Science ®Google Scholar
• Mølbak , K. 2004 . Spread of resistant bacteria and resistance genes from animals to humans–the public health consequences . J. Vet. Med. , 51 ( 8–9 ) : 364 – 369 .
   Google Scholar
• Monnet , D. L. 2005 . Antibiotic development and the changing role of the pharmaceutical industry . Int. J. Risk Safety Med. , 17 : 133 – 145 .
   Google Scholar
• Moorman , M. A. , Thelemann , C. A. , Zhou , S. , Pestka , J. J. , Linz , J. E. and Ryser , E. T. 2008 . Altered hydrophobicity and membrane composition in stress-adapted Listeria innocua . J. Food Protect. , 71 ( 1 ) : 182 – 185 .
   Web of Science ®Google Scholar
• Muirhead , S. 2002 . Therapeutic use of antibiotics on rise in Denmark . Feedstuffs , 74 : 1 – 5 .
   Google Scholar
• Mulvey , M. R. and Simor , A. E. 2009 . Antimicrobial resistance in hospitals: How concerned should we be? . Can. Med. Assoc. J. , 180 ( 4 ) : 408 – 415 .
   PubMed Web of Science ®Google Scholar
• Naghmouchi , K. , Kheadr , E. , Lacroix , C. and Fliss , I. 2007 . Class I/Class IIa bacteriocin cross-resistance phenomenon in Listeria monocytogenes . Food Microbiol. , 24 ( 7–8 ) : 718 – 727 .
   Web of Science ®Google Scholar
• NARMS . 2006 . National Antimicrobial Resistance Monitoring System: Enteric bacteria. 2006. Human Isolates Final Report. Centers for Disease Control and Prevention . Available at: http://www.cdc.gov/narms/annual/2006/NARMSAnnualReport2006.pdf. Date last accessed: May 7, 2010.
   Google Scholar
• Neetoo , H. , Pizzolato , T. and Chen , H. 2009 . Elimination of Escherichia coli O157:H7 from alfalfa seeds through a combination of high hydrostatic pressure and mild heat . Appl. Environ. Microbiol. , 75 ( 7 ) : 1901 – 1907 .
   Web of Science ®Google Scholar
• Nicholson , F. A. , Chambers , B. J. , Moore , A. , Nicholson , R. J. and Hickman , G. 2004 . Assessing and managing the risks of pathogen transfer from livestock manures into the food chain . Water Environ. J. , 18 ( 3 ) : 155 – 160 .
   Web of Science ®Google Scholar
• Nielsen , K. M. , Van Elsas , J. D. and Smalla , K. 2001 . Dynamics, horizontal transfer and selection of novel DNA in bacterial populations in the phytosphere of transgenic plants . Ann. Microbiol. , 51 ( 1 ) : 79 – 94 .
   Web of Science ®Google Scholar
• Nijsten , R. , London , N. , van den Bogaard , A. and Stobberingh , E. 1994 . Resistance in faecal Escherichia coli isolated from pig farmers and abattoir workers . Epidemiol. Infect , 113 ( 1 ) : 45 – 52 .
   Web of Science ®Google Scholar
• Ogden , I. D. , Hepburn , N. F. , MacRae , M. , Strachan , N. J.C. , Fenlon , D. R. , Rusbridge , S. M. and Pennington , T. H. 2002 . Long-term survival of Escherichia coli O157 on pasture following an outbreak associated with sheep in a scout camp . Lett. Appl. Microbiol. , 34 ( 2 ) : 100 – 104 .
   Web of Science ®Google Scholar
• OIE . 2006 . Guide to good farming practices for animal production food safety. OIE Animal Production Food Safety Working Group . Rev. Sci. Tech. Off. Int. Epiz. , 25 ( 2 ) : 823 – 836 . Available at: http://www.oie.int/boutique/extrait/25berlingueri823836_0.pdf. Date last accessed: July 14, 2010.
   Web of Science ®Google Scholar
• OIE . 2010 . Terrestrial animal health code. Responsible and prudent use of antimicrobial agents in veterinary medicine. Health standards of the World Organization for Animal Health . Available at: http://www.oie.int/eng/normes/mcode/en_chapitre_1.6.9.pdf. Date last accessed: August 20, 2010.
   Google Scholar
• OJEC . 1990 . Council Regulation (EEC) No 2377/90 of 26 June 1990 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin . Off. J. European Comm. , : 1 – 8 . 18/08/1990 L224 Available at: http://ec.europa.eu/health/files/eudralex/vol-5/reg_1990_2377/reg_1990_2377_en.pdf. Date last accessed: August 20, 2010.
   Google Scholar
• OJEC . 1991 . Council Directive 91/271/EEC of 21 May 1991 concerning urban waste-water treatment . Off. J. European Comm. , : 40 – 52 . 30/05/1991 L135 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:31991L0271:EN:HTML. Date last accessed: July 15, 2010.
   Google Scholar
• OJEC . 1996 . Council Directive 96/23/EC of 29 April 1996 on measures to monitor certain substances and residues thereof in live animals and animal products and repealing Directives 85/358/EEC and 86/469/EEC and Decisions 89/187/EEC and 91/664/EEC . Off. J. European Comm. , : 10 – 32 . 23/05/1996 L125 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:31996L0023:EN:HTML. Date last accessed: May 6, 2010.
   Google Scholar
• OJEC . 1997 . Commission Directive 97/6/EC of 30 January 1997 amending Council Directive 70/524/EEC concerning additives in feedingstuffs . Off. J. European Comm. , : 11 – 13 . 05/02/2007 L35 Available at: http://eur-lex.europa.eu/Notice.do?mode=dbl&lng1=en,es&lang=&lng2=cs,da,de,el, en,es,et,fi,fr,hu,it,lt,lv,mt,nl,pl,pt,sk,sl,sv,&val=218496:cs&page=&hwords =null. Date last accessed: May 7, 2010.
   Google Scholar
• OJEC . 1998a . Directive 98/8/EC of the European parliament and of the Council of 16 February 1998 concerning the placing of biocidal products on the market . Off. J. European Comm. , : 1 – 63 . 24/04/1998 L123 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:1998:123:0001:0001:E N:PDF. Date last accessed: May 7, 2010.
   Google Scholar
• OJEC . 1998b . Council Regulation (EC) No 2821/98 of 17 December 1998 amending, as regards withdrawal of the authorisation of certain antibiotics, Directive 70/524/EEC concerning additives in feedingstuffs . Off. J. European Comm. , L351 : 4 – 8 . 29/12/1998 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:1998:351:0004:0008:EN:PDF. Date last accessed: May 7, 2010.
   Google Scholar
• OJEC . 1998c . Commission Regulation (EC) No 2788/98 of 22 December 1998 amending Council Directive 70/524/EEC concerning additives in feedingstuffs as regards the withdrawal of authorisation for certain growth promoters . Off. J. European Comm. , L347 : 31 – 32 . 23/12/1998 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:1998:347:0031:0032:EN:PDF. Date last accessed: May 7, 2010.
   Google Scholar
• OJEC . 1998d . Council Directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption . Off. J. European Comm. , L330 : 32 – 54 . 05/12/1998 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:1998:330:0032:0054:EN:PDF. Date last accessed: May 6, 2010.
   Google Scholar
• OJEC . 2001a . Directive 2001/82/EC of the European Parliament and of the Council of 6 November 2001 on the Community code relating to veterinary medicinal products . Off. J. European Comm. , L311 : 1 – 66 . 28/11/2001 Available at: http://faolex.fao.org/docs/pdf/eur36747.pdf. Date last accessed: August 20, 2010.
   Google Scholar
• OJEC . 2001b . Directive 2001/18/EC of the European Parliament and of the Council of 12 March 2001 on the deliberate release into the environment of genetically modified organisms and repealing Council Directive 90/220/EEC . Off. J. European Comm. , L106 : 1 – 38 . 17/04/2001 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2001:106:0001:0038:EN: PDF. Date last accessed: May 7, 2010.
   Google Scholar
• OJEC . 2002 . Regulation (EC) No 1774/2002 of the European Parliament and of the Council of 3 October 2002 laying down health rules concerning animal by-products not intended for human consumption . Off. J. European Comm. , L273 : 1 – 95 . 10/10/2002 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2002:273:0001:0095:EN: PDF. Date last accessed: June 25, 2010.
   Google Scholar
• OJEU . 2003a . Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition . Off. J. European Union , L268 : 29 – 43 . Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2003:268:0029:0043:EN:PDF. Date last accessed: August 18, 2010.
   Google Scholar
• OJEU . 2003b . Regulation (EC) No 1829/2003 of the European Parliament and of the Council of 22 September 2003 on genetically modified food and feed . Official J European Union , L268 : 1 – 23 . 18/10/2003 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2003:268:0001:0023: EN:PDF. Date last accessed: May 8, 2010.
   Google Scholar
• OJEU . 2003c . Regulation (EC) No 1830/2003of the European Parliament and of the Council of 22 September 2003 concerning the traceability and labelling of genetically modified organisms and the traceability of food and feed products produced from genetically modified organisms and amending Directive 2001/18/EC . Official J. European Union , L268 : 24 – 28 . 18/10/2003 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2003:268:0024:0028:EN:PDF. Date last accessed: May 8, 2010.
   Google Scholar
• OJEU . 2004a . Regulation (EC) No 726/2004 of the European Parliament and of the Council of 31 March 2004 laying down Community procedures for the authorisation and supervision of medicinal products for human and veterinary use and establishing a European Medicines Agency . Off. J. European Union , L136 : 1 – 33 . 30/04/2004 Available at: http://apps.who.int/medicinedocs/documents/s17139e/s17139e.pdf. Date last accessed: August 20, 2010.
   Google Scholar
• OJEU . 2004b . Regulation (EC) No 853/2004 of the European Parliament and of the Council of 29 April 2004 laying down specific hygiene rules for food of animal origin . Off. J. European Union , L139 : 55 – 205 . 30/04/2004 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2004:139:0055:0205:EN:PDF. Date last accessed: August 20, 2010.
   Google Scholar
• OJEU . 2004c . Regulation (EC) No 852/2004 of the European Parliament and of the Council of 29 April 2004 on the hygiene of foodstuffs . Off. J. European Union , L139 : 1 – 54 . 30/04/2004 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2004:139:0001:0054:EN: PDF. Date last accessed: August 20, 2010.
   Google Scholar
• OJEU . 2005a . Regulation (EC) No 396/2005 of the European Parliament and of the Council of 23 February 2005 on maximum residue levels of pesticides in or on food and feed of plant and animal origin and amending Council Directive 91/414/EEC . Off. J. European Union , L70 : 1 – 16 . 16/03/2005 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2005:070:0001:0016:en:PDF. Date last accessed: May 8, 2010.
   Google Scholar
• OJEU . 2005b . Regulation (EC) No 183/2005 of the European Parliament and of the Council of 12 January 2005 laying down requirements for feed hygiene . Off. J. European Union , L35 : 1 – 22 . 08/02/2005 Available at: http://eur-http://eur-lex.europa.eu/LexUriServ/site/en/oj/2005/l_035/l_03520050208en00010022.pdf. Date last accessed: July 6, 2010.
   Google Scholar
• OJEU . 2006 . Commission Regulation (EC) No 1177/2006 of 1 August 2006 implementing Regulation (EC) No 2160/2003 of the European Parliament and of the Council as regards requirements for the use of specific control methods in the framework of the national programmes for the control of Salmonella in poultry . Off. J. European Union , L212 : 3 – 5 . 02/08/2006 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2006:212:0003:0005:EN:PDF. Date last accessed: June 23, 2010.
   Google Scholar
• OJEU . 2008 . Regulation (EC) No 1333/2008 of the European Parliament and of the Council of 16 December 2008 on food additives . Off. J. European Union , L354 : 16 – 33 . 31/12/2008 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2008:354:0016:0033:en:PDF. Date last accessed: May 8, 2010.
   Google Scholar
• OJEU . 2009a . Commission Directive 2009/9/EC of 10 February 2009 amending Directive 2001/82/EC of the European Parliament and of the Council on the Community code relating to medicinal products for veterinary use . Off. J. European Union , L44 : 10 – 61 . 14/02/2009 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:044:0010:0061: EN:PDF. Date last accessed: May 8, 2010.
   Google Scholar
• OJEU . 2009b . Council Decision 2009/121/EC of 18 December 2008 rejecting the proposal from the Commission for a Council Regulation implementing Regulation (EC) No 853/2004 of the European Parliament and of the Council as regards the use of antimicrobial substances to remove surface contamination from poultry carcasses . Off. J. European Union , L42 : 13 – 15 . 13/02/2009 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:042:0013:0015:EN:PDF. Date last accessed: May 8, 2010.
   Google Scholar
• OJEU . 2009c . Directive 2009/41/EC of the European Parliament and of the Council of 6 May 2009 on the contained use of genetically modified micro-organisms . Official J. European Union , L127 : 75 – 97 . 21/05/2009 Available at: http://www.bmwf.gv.at/fileadmin/user_upload/forschung/gentechnik/2009-41-EC.pdf. Date last accessed: May 8, 2010
   Google Scholar
• OJEU . 2009d . Regulation (EC) No 1069/2009 of the European Parliament and of the Council of 21 October 2009 laying down health rules as regards animal by-products and derived products not intended for human consumption and repealing regulation (EC) No 1774/2002 (Animal by-products Regulation) . Official J. European Union , L300 : 1 – 33 . 14/11/2009 Available at: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:300:0001:0033: EN:PDF. Date last accessed: June 27, 2010.
   Google Scholar
• Pan , Y. , Breidt , F. and Kathariou , S. 2006 . Resistance of Listeria monocytogenes biofilms to sanitizing agents in a simulated food processing environment . Appl. Environ. Microbiol. , 72 ( 12 ) : 7711 – 7717 .
   PubMed Web of Science ®Google Scholar
• Patterson , D. L. and Rice , L. B. 2003 . Empirical antibiotic choice for the seriously ill patients: Are minimization of selection resistant organisms and maximization of individual outcome mutually exclusive? . Clin. Infect. Dis. , 36 ( 8 ) : 1006 – 1012 .
   Web of Science ®Google Scholar
• Perić , L. , Žikić , D. and Lukić , M. 2009 . Application of alternative growth promoters in broiler production . Biotech. Anim. Husb. , 25 ( 5–6 ) : 387 – 397 .
   Google Scholar
• Peters , J. , Mac , K. , Wichmann-Schauer , H. , Klein , G. and Ellerbroek , L. 2003 . Species distribution and antibiotic resistance patterns of enterococci isolated from food of animal origin in Germany . Int. J. Food Microbiol. , 88 ( 2–3 ) : 311 – 314 .
   Web of Science ®Google Scholar
• Phillips , I. 2007 . Withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health . Int. J. Antimicrob. Agents , 30 ( 2 ) : 101 – 107 .
   PubMed Web of Science ®Google Scholar
• Potenski , C. J. , Gandhi , M. and Matthews , K. R. 2003 . Exposure of Salmonella Enteritidis to chlorine or food preservatives increases susceptibility to antibiotics . FEMS Microbiol. Lett. , 220 ( 2 ) : 181 – 186 .
   Web of Science ®Google Scholar
• Projan , S. J. 2003 . Why is big Pharma getting out of antimicrobial drug discovery? . Curr. Opin. Microbiol. , 6 ( 5 ) : 427 – 430 .
   PubMed Web of Science ®Google Scholar
• Rajbhandary , S. S. , Marks , S. M. and Bock , N. N. 2004 . Costs of patients hospitalized for multidrug-resistant tuberculosis . Int. J. Tuberc. Lung D. , 8 ( 8 ) : 1012 – 1016 .
   Web of Science ®Google Scholar
• Rajkovic , A. , Smigic , N. , Uyttendaele , M. , Medic , H. , Zutter , L. de and Devlieghere , F. 2009 . Resistance of Listeria monocytogenes, Escherichia coli O157:H7 and Campylobacter jejuni after exposure to repetitive cycles of mild bactericidal treatments . Food Microbiol. , 26 ( 8 ) : 889 – 895 .
   Web of Science ®Google Scholar
• Rajkovic , A. , Smigic , N. and Devlieghere , F. 2010 . Review. Contemporary strategies in combating microbial contamination in food chain . Int. J. Food Microbiol. , 141 ( suppl. 1 ) : S29 – S42 .
   Google Scholar
• Randall , L. P. , Cooles , S. W. , Coldham , N. G. , Penuela , E. G. , Mott , A. C. , Woodward , M. J. , Piddock , L. J.V. and Webber , M. A. 2007 . Commonly used farm disinfectants can select for mutant Salmonella enterica serovar Typhimurium with decreased susceptibility to biocides and antibiotics without compromising virulence . J. Antimicrob. Ch. , 60 ( 6 ) : 1273 – 1280 .
   Web of Science ®Google Scholar
• Rice , L. B. 2009 . The clinical consequences of antimicrobial resistance . Curr. Opin. Microbiol. , 12 ( 5 ) : 476 – 481 .
   PubMed Web of Science ®Google Scholar
• Rickard , A. H. , Lindsay , S. , Lockwood , G. B. and Gilbert , P. 2004 . Induction of the mar operon by miscellaneous groceries . J. Appl. Microbiol. , 97 ( 5 ) : 1063 – 1068 .
   PubMed Web of Science ®Google Scholar
• Roberts , R. R. , Hota , B. , Ahmad , I. , Scott , R. D. , Foster , S. D. , Abbasi , F. , Schabowski , S. , Kampe , L. M. , Ciavarella , G. G. , Supino , M. , Naples , J. , Cordell , R. , Levy , S. B. and Weinstein , R. A. 2009 . Hospital and societal costs of antimicrobial-resistant infections in a Chicago, teaching hospital: implications for antibiotic stewardship . Clin. Infect. Dis. , 49 ( 8 ) : 1175 – 1184 .
   PubMed Web of Science ®Google Scholar
• Rodrigo , D. , Sampedro , F. , Silva , A. , Palop , A. and Martínez , A. 2010 . New food processing technologies as a paradigm of safety and quality . Brit. Food J. , 112 ( 5 (9) : 467 – 475 .
   Web of Science ®Google Scholar
• Rosen , G. D. 2004 . Optimizing the replacement of pronutrient antibiotics in poultry nutrition . : 93 – 101 . Proceedings of Alltech's 20th Annual International Symposium Alltech, Lexington
   Google Scholar
• Rosenblatt-Farrell , N. 2009 . The landscape of antibiotic resistance . Environ. Health Persp. , 117 ( 6 ) : A245 – A250 .
   Web of Science ®Google Scholar
• Ross , G. R. , Gusils , C. , Oliszewski , R. , Colombo de Holgado , S. and González , S. N. 2010 . Effects of probiotic administration in swine . J. Biosci. Bioeng. , 109 ( 6 ) : 545 – 549 .
   Web of Science ®Google Scholar
• Rowan , N. J. 1999 . Evidence that inimical food-preservation barriers alter microbial resistance, cell morphology and virulence . Trends Food Sci. Tech. , 10 ( 8 ) : 261 – 270 .
   Web of Science ®Google Scholar
• Sanyal , D. and Greenwood , D. 1993 . An electronmicroscope study of glycopeptide antibiotic-resistant strains of Staphylococcus epidermidis . J. Med. Microbiol. , 39 : 204 – 210 .
   PubMed Web of Science ®Google Scholar
• SCENIHR . 2009 . Assessment of the Antibiotic Resistance Effects of Biocides. Scientific Committee on Emerging and Newly Identified Health Risks, 19 January 2009 . Available at: http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_021.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• SCHER-SCENIHR . 2008 . SCHER/SCENIHR scientific opinion on the environmental impact and effect on antimicrobial resistance of four substances used for the removal of microbial surface contamination of poultry carcasses, April 2008 . Available at: http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_015.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• Schmitz , F.-J. , Perdikouli , M. , Beeck , A. , Verhoef , J. , Fluit , A. C. and for the European SENTRY participants . 2001 . Resistance to trimethoprim-sulfamethoxazole and modifications in genes coding for dihydrofolate reductase and dihydropteroate synthase in European Streptococcus pneumoniae isolates . J. Antimicrob. Ch , 48 : 931 – 942 .
   Web of Science ®Google Scholar
• Scopa , A. , Candido , V. , Dumontet , S. , Pasquale , V. and Miccolis , V. 2009 . Repeated solarization and long-term effects on soil microbiological parameters and agronomic traits . Crop Prot. , 28 ( 10 ) : 818 – 824 .
   Web of Science ®Google Scholar
• Seifert , S. and Watzl , B. 2007 . Inulin and oligofructose: review of experimental data on inmune modulation . J. Nutr. , 137 ( 11 ) : 2563S – 2567S .
   PubMed Web of Science ®Google Scholar
• Sheldon , A. T. Jr. 2005 . Antiseptic “resistance”: Real or perceived threat? . Clin. Infect. Dis. , 40 ( 11 ) : 1650 – 1656 .
   Web of Science ®Google Scholar
• Shi , X. and Zhu , X. 2009 . Biofilm formation and food safety in food industries . Trends Food Sci. Tech. , 20 ( 9 ) : 407 – 413 .
   Web of Science ®Google Scholar
• Sidhu , J. , Gibbs , R. A. , Ho , G. E. and Unkovich , I. 2001 . The role of indigenous micoorganisms in suppression of Salmonella regrowth in composted biosolids . Water Res. , 35 ( 4 ) : 913 – 920 .
   Web of Science ®Google Scholar
• Sidhu , M. S. , Heir , E. , Leegaard , T. , Wiger , K. and Holck , A. 2002 . Frequency of disinfectant resistance genes and genetic linkage with beta-lactamase transposon Tn552 among clinical staphylococci . Antimicrob. Agents Ch. , 46 ( 9 ) : 2797 – 2803 .
   PubMed Web of Science ®Google Scholar
• Singer , R. S. , Cox , L. A. , Dickson , J. S. , Hurd , H. S. , Phillips , I. and Miller , G. Y. 2007 . Modeling the relationship between food animal health and human foodborne illness . Prev. Vet. Med. , 79 ( 2–4 ) : 186 – 203 .
   Web of Science ®Google Scholar
• Singer , R. S. , Finch , R. , Wegener , H. C. , Bywater , R. , Walters , J. and Lipsitch , M. 2003 . Antibiotic resistance - the interplay between antibiotic use in animals and human beings . Lancet Infect. Dis. , 3 ( 1 ) : 47 – 51 .
   Web of Science ®Google Scholar
• Smith , K. and Hunter , I. S. 2008 . Efficacy of common hospital biocides with biofilms of multi-drug resistant clinical isolates . J. Med. Microbiol. , 57 ( Pt 8 ) : 966 – 973 .
   PubMed Web of Science ®Google Scholar
• Sørum , H. 2006 . “ Antimicrobial Drug Resistance in Fish Pathogens ” . In Antimicrobial Resistance in Bacteria of Animal origin , Edited by: Aarestrup , F. M. 213 – 238 . Washington , DC : American Society for Microbiology Press .
   Google Scholar
• Spellberg , B. , Powers , J. H. , Brass , E. P. , Miller , L. G. and Edwards , J. E. Jr. 2004 . Trends in antimicrobial drug development: implications for the future . Clin. Infect. Dis. , 38 ( 9 ) : 1279 – 1286 .
   PubMed Web of Science ®Google Scholar
• Spellberg , B. 2008 . Antibiotic resistance and antibiotic development . Lancet Infect. Dis. , 8 ( 4 ) : 211 – 212 .
   PubMed Web of Science ®Google Scholar
• Stein , A. J. and Rodríguez-Cerezo , E. 2009 . The global pipeline of new GM crops. Implications of asynchronous approval for international trade. Institute for Prospective Technological Studies, Joint Research Centre, European Commission. EUR 23486 EN – 2009 . Available at: http://ftp.jrc.es/EURdoc/report_GMOpipeline_online_preprint.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• Stickler , D. J. 2004 . “ Intrinsic resistance of Gram-negative bacteria ” . In Principles and Practice of Disinfection, Preservation and Sterilization 4th ed. , Edited by: Fraise , A. P. , Lambert , P. A. and Maillard , J.-Y. 154 – 168 . Oxford : Blackwell Scientific Publication .
   Google Scholar
• Stickler , D. J. and Jones , G. L. 2008 . Reduced Susceptibility of Proteus mirabilis to triclosan . Antimicrob. Agents Ch. , 52 ( 3 ) : 991 – 994 .
   Web of Science ®Google Scholar
• Swennen , K. , Courtin , C. M. and Delcour , J. A. 2006 . Non-digestible oligosaccharides with prebiotic properties . Crit. Rev. Food Sci. Nutr. , 46 ( 6 ) : 459 – 471 .
   PubMed Web of Science ®Google Scholar
• Szczepanowski , R. , Krahn , I. , Linke , B. , Goesmann , A. , Pühler , A. and Schlüter , A. 2004 . Antibiotic multiresistance plasmid pRSB101 isolated from a wastewater treatment plant is related to plasmids residing in phytopathogenic bacteria and carries eight different resistance determinants including a multidrug transport system . Microbiol. , 150 : 3613 – 3630 .
   PubMed Web of Science ®Google Scholar
• Tarver , T. 2008 . “Just add water”: Regulating and protecting the most common ingredient . J. Food Sci. , 73 ( 1 ) : R1 – R13 .
   Web of Science ®Google Scholar
• Thomas , L. , Maillard , J.-Y. , Lambert , R. J.W. and Russell , A. D. 2000 . Development of resistance to chlorhexidine diacetate in Pseudomonas aeruginosa and the effect of a “residual” concentration . J. Hosp. Infect. , 46 ( 4 ) : 297 – 303 .
   PubMed Web of Science ®Google Scholar
• Thorrold , C. A. , Letsoalo , M. E. , Dusé , A. G. and Marais , E. 2007 . Efflux pump activity in fluoroquinolone and tetracycline resistant Salmonella and E. coli implicated in reduced susceptibility to household antimicrobial cleaning agents . Int. J. Food Microbiol. , 113 ( 3 ) : 315 – 320 .
   Web of Science ®Google Scholar
• Tkachenko , O. , Shepard , J. , Aris , V. M. , Joy , A. , Bello , A. , Londono , I. , Marku , J. , Soteropoulos , P. and Peteroy-Kelly , M. A. 2007 . A triclosan-ciprofloxacin cross-resistant mutant strain of Staphylococcus aureus displays an alteration in the expression of several cell membrane structural and functional genes . Res. Microbiol. , 158 ( 8–9 ) : 651 – 658 .
   PubMed Web of Science ®Google Scholar
• Trémolières , F. , Cohen , R. , Gauzit , R. , Vittecoq , D. and Stahl , J.-P. 2010 . Save antibiotics. What can be done to prevent a forecasted disaster! Suggestions to promote the development of new antibiotics . Med. Mal. Infect. , 40 ( 3 ) : 129 – 134 .
   Web of Science ®Google Scholar
• Tuovinen , V. 2004 . Biosecurity measures in animal husbandry to prevent epidemic zoonoses. International seminar and exhibition on animal feed biotechnology, United Nations Asian and Pacific Centre for Agricultural Engineering and Machinery . Available at: http://unapcaem.org/Activities%20Files/A16/Biosecurity%20measures%20in%20animal%20husbandry.pdf. Date last accessed: July 14, 2010.
   Google Scholar
• Ungemach , F. R. 2000 . Figures on quantities of antibacterials used for different purposes in the EU countries and interpretation . Acta Vet. Scand. , 93 : 89 – 98 . Suppl.
   Google Scholar
• Valenzuela , A. S. , Omar , N. B. , Abriouel , H. , López , R. L. , Ortega , E. , Cañamero , M. M. and Gálvez , A. 2008 . Risk factors in enterococci isolated from foods in Morocco: Determination of antimicrobial resistance and incidence of virulence traits . Food Chem. Toxicol. , 46 ( 8 ) : 2648 – 2652 .
   Web of Science ®Google Scholar
• Valkova , N. , Lépine , F. , Valeanu , L. , Dupont , M. , Labrie , L. , Bisaillon , J. G. , Beaudet , R. , Shareck , F. and Villemur , R. 2001 . Hydrolysis of 4-hydroxybenzoic acid esters (parabens) and their aerobic transformation into phenol by the resistant Enterobacter cloacae strain EM . Appl. Environ. Microbiol. , 67 ( 6 ) : 2404 – 2409 .
   Web of Science ®Google Scholar
• Van den Bogaard , A. E. and Stobberingh , E. E. 2000 . Epidemiology of resistance to antibiotics links between animals and humans . Int. J. Antimicrob. Agents , 14 ( 4 ) : 327 – 335 .
   PubMed Web of Science ®Google Scholar
• Van Loenen , M. C.A. , Turbett , Y. , Mullins , C. E. , Feilden , N. E.H. , Wilson , M. J. , Leifert , C. and Seel , W. E. 2003 . Low temperature-short duration steaming of soil kills soil-borne pathogens, nematode pests and weeds . Eur. J. Plant. Pathol. , 109 ( 9 ) : 993 – 1002 .
   Web of Science ®Google Scholar
• Varma , J. K. , Marcus , R. , Stenzel , S. A. , Hanna , S. S. , Gettner , S. , Anderson , B. J. , Hayes , T. , Shiferaw , B. , Crume , T. L. , Joyce , K. , Fullerton , K. E. , Voetsch , A. C. and Angulo , F. J. 2006 . Highly resistant Salmonella Newport-MDRAmpC transmitted through the domestic US food supply: a FoodNet case-control study of sporadic Salmonella Newport infections, 2002–2003 . J. Infect. Dis. , 194 ( 2 ) : 222 – 230 .
   Web of Science ®Google Scholar
• Velkov , V. V. 1999 . How environmental factors regulate mutagenesis and gene transfer in microorganisms . J. Biosci. , 24 ( 4 ) : 529 – 559 .
   Web of Science ®Google Scholar
• Venglovsky , J. , Sasakova , N. and Placha , I. 2009 . Pathogens and antibiotic residues in animal manures and hygienic and ecological risks related to subsequent land application . Biores. Technol. , 100 ( 22 ) : 5386 – 5391 .
   Web of Science ®Google Scholar
• Vidaver , A. K. 2002 . Uses of antimicrobials in plant agriculture . Clin Infect. Dis. , 34 ( Suppl. 3 ) : S107 – S110 .
   Google Scholar
• Viola , C. and DeVincent , S. J. 2006 . Overview of issues pertaining to the manufacture, distribution, and use of antimicrobials in animals and other information relevant to animal antimicrobial use data collection in the United States . Prev. Vet. Med. , 73 ( 2–3 ) : 111 – 131 .
   PubMed Web of Science ®Google Scholar
• Visarada , K. B.R.S. , Meena , K. , Aruna , C. , Srujana , S. , Saikishore , N. and Seetharama , N. 2009 . Transgenic breeding: perspectives and prospects . Crop Sci , 49 ( 5 ) : 1555 – 1563 .
   Web of Science ®Google Scholar
• Von Wright , A. and Bruce , A. 2003 . Genetically modified microorganisms and their potential effects on human health and nutrition . Trends Food Sci. Tech. , 14 ( 5–8 ) : 264 – 276 .
   Web of Science ®Google Scholar
• Walker , R. A. , Lawson , A. J. , Lindsay , E. A. , Ward , L. R. , Wright , P. A. , Bolton , F. J. , Wareing , D. R. , Corkish , J. D. , Davies , R. H. and Threlfall , E. J. 2000 . Decreased susceptibility to ciprofloxacin in outbreak-associated multiresistant Salmonella Typhimurium DT104 . Vet. Rec. , 147 ( 14 ) : 395 – 396 .
   Web of Science ®Google Scholar
• Wang , G. , Zhao , T. and Doyle , M. P. 1996 . Fate of enterohemorrhagic Escherichia coli O157:H7 in bovine faeces . Appl. Environ. Microbiol , 62 ( 7 ) : 2567 – 2570 .
   Web of Science ®Google Scholar
• Wassenaar , T. M. and Klein , G. 2008 . Safety aspects and implications of regulation of probiotic bacteria in food and food supplements . J Food Protect. , 71 ( 8 ) : 1734 – 1741 .
   PubMed Web of Science ®Google Scholar
• Watson , R. 2008 . Multidrug resistance responsible for half of deaths from healthcare associated infections in Europe . Brit. Med. J. , 336 ( 7656 ) : 1266 – 1267 .
   Web of Science ®Google Scholar
• Webber , D. and Kremer , M. 2001 . Perspectives on stimulating industrial research and development for neglected infectious diseases . B. World Health Organ. , 79 ( 8 ) : 735 – 741 .
   PubMed Web of Science ®Google Scholar
• Weese , J. S. , Dick , H. , Willey , B. M. , McGeer , A. , Kreiswirth , B. N. , Innis , B. and Low , D. E. 2006 . Suspected transmission of methicillin-resistant Staphylococcus aureus between domestic pets and humans in veterinary clinics and in the household . Vet. Microbiol. , 115 ( 1–3 ) : 148 – 155 .
   PubMed Web of Science ®Google Scholar
• WHO . 1997 . The medical impact of antimicrobial use in food animals . Report of a World Health Organization meeting, Berlin, Germany, 13–17 October 1997. Available at: http://whqlibdoc.who.int/hq/1997/WHO_EMC_ZOO_97.4.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2000 . World Health Organization global principles for the containment of antimicrobial resistance in animals intended for food . Report of a WHO consultation with the participation of the Food and Agriculture Organization of the United Nations (FAO) and the Office International des Epizooties (OIE), Geneva, Switzerland, 5–9 June, 2000. Available at: http://whqlibdoc.who.int/hq/2000/WHO_CDS_CSR_APH_2000.4.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2001 . World Health Organization global strategy for containment of antimicrobial resistance . Available at: http://www.who.int/csr/resources/publications/drugresist/WHO_CDS_CSR_DRS_2001_2_EN/en/. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2002 . World Health Organization. Antimicrobial resistance. Fact sheet N° 194 . Available at: http://www.who.int/mediacentre/factsheets/fs194/en/. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2003 . Impacts of antimicrobial growth promoter termination in Denmark . WHO/CDS/CPE/ZFK/2003.1 Document. World Health Organization, Foulum, Denmark. Available at: http://whqlibdoc.who.int/hq/2003/WHO_CDS_CPE_ZFK_2003.1.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2004 . Second Joint FAO/OIE/WHO Expert Workshop on Non-Human Antimicrobial Usage and Antimicrobial Resistance: Management options, 15–18 March 2004. Oslo, Norway . Available at: http://www.who.int/foodsafety/publications/micro/en/oslo_report.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2006 . Antimicrobial use in aquaculture and antimicrobial resistance. Report of a Joint FAO/OIE/WHO expert consultation. World Health Organization, Seoul, Republic of Korea, 13–16 June, 2006 . Available at: ftp://ftp.fao.org/ag/agn/food/aquaculture_rep_13_16june2006.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2007a . The world health report 2007 - A safer future: global public health security in the 21st century . Available at: http://www.who.int/whr/2007/en/index.html. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2007b . Critically Important Antimicrobials for Human Medicine: Categorization for the Development of Risk Management Strategies to contain Antimicrobial resistance due to Non-Human Antimicrobial Use. Report of the Second WHO Expert Meeting Copenhagen, 29–31 May 2007. Copenhagen, 29–31 May 2007 . Available at: http://www.who.int/foodborne_disease/resistance/antimicrobials_human.pdf. Date last accessed: May 8, 2010.
   Google Scholar
• WHO . 2009 . World Health Organization. Related WHO publications and links on antimicrobial resistance . Available at: http://www.who.int/foodborne_disease/resistance/publications/en/index.html. Date last accessed: May 8, 2010.
   Google Scholar
• Wierup , M. 2001a . The Swedish experience of the 1986 year ban of antimicrobial growth promoters, with special reference to animal health, disease prevention, productivity, and usage of antimicrobials . Microb. Drug Resist. , 7 ( 2 ) : 183 – 190 .
   PubMed Web of Science ®Google Scholar
• Wierup , M. 2001b . The experience of reducing antibiotics used in animal production in the Nordic countries . Int. J. Antimicrob. Ag. , 18 ( 3 ) : 287 – 290 .
   PubMed Web of Science ®Google Scholar
• Williams , G. J. and Stickler , D. J. 2008 . Effect of triclosan on the formation of crystalline biofilms by mixed communities of urinary tract pathogens on urinary catheters . J. Med. Microbiol. , 57 ( 9 ) : 1135 – 1140 .
   PubMed Web of Science ®Google Scholar
• Wilton , P. , Smith , R. D. , Coast , J. , Millar , M. and Karcher , A. 2001 . Directly observed treatment for multidrug-resistant tuberculosis: An economic evaluation in the United States of America and South Africa . Int. J. Tuberc. Lung D. , 5 ( 12 ) : 1137 – 1142 .
   PubMed Web of Science ®Google Scholar
• Winder , C. L. , Al-Adham , I. S.I. , Abdel Malek , S. M.A. , Buultjens , T. E.J. , Horrocks , A. J. and Collier , P. J. 2000 . Outer membrane protein shifts in biocide-resistant Pseudomonas aeruginosa PAO1 . J. Appl. Microbiol. , 89 ( 2 ) : 289 – 295 .
   PubMed Web of Science ®Google Scholar
• Yakabe , T. , Moore , E. L. , Yokota , S. , Sui , H. , Nobuta , Y. , Fukao , M. , Palmer , H. and Yajima , N. 2009 . Safety assessment of Lactobacillus brevis KB290 as a probiotic strain . Food Chem. Toxicol. , 47 ( 10 ) : 2450 – 2453 .
   Web of Science ®Google Scholar
• Yin , H. , Zhao , X. and Du , Y. 2010 . Oligochitosan: a plant disease vaccine: A review . Carbohyd. Polym. , 82 ( 1 ) : 1 – 8 .
   Web of Science ®Google Scholar