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The future is bright: Biofortification of common foods can improve vitamin D status

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References

  • Aguilera, J. M. 2019. The food matrix: implications in processing, nutrition and health. Critical Reviews in Food Science and Nutrition 59 (22):3612–29. doi: 10.1080/10408398.2018.1502743.
  • Alexander, B. M., B. C. Ingold, J. L. Young, S. R. Fensterseifer, P. J. Wechsler, K. J. Austin, and D. E. Larson-Meyer. 2017. Sunlight exposure increases vitamin D sufficiency in growing pigs fed a diet formulated to exceed requirements. Domestic Animal Endocrinology 59:37–43. 10.1016/j.domaniend.2016.10.006. doi: 10.1016/j.domaniend.2016.10.006.
  • Armas, L. A., B. W. Hollis, and R. P. Heaney. 2004. Vitamin D2 is much less effective than vitamin D3 in humans. The Journal of Clinical Endocrinology & Metabolism 89 (11):5387–91. doi: 10.1210/jc.2004-0360.
  • Aune, D., D. S. Chan, A. R. Vieira, D. A. Navarro Rosenblatt, R. Vieira, D. C. Greenwood, E. Kampman, and T. Norat. 2013. Red and processed meat intake and risk of colorectal adenomas: a systematic review and meta-analysis of epidemiological studies. Cancer Causes & Control 24 (4):611–27. doi: 10.1007/s10552-012-0139-z.
  • Banlangsawan, N., and N. Sanoamuang. 2016. Effect of UV-B irradiation on contents of ergosterol, vitamin D2, vitamin B1 and vitamin B2 in Thai edible mushrooms. Chiang Mai Journal of Science 43 (1):45–53.
  • Barger-Lux, M. J., R. P. Heaney, S. Dowell, T. C. Chen, and M. F. Holick. 1998. Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men. Osteoporosis International 8 (3):222–30. doi: 10.1007/s001980050058.
  • Barnkob, L. L., A. Argyraki, and J. Jakobsen. 2020. Naturally enhanced eggs as a source of vitamin D: a review. Trends in Food Science & Technology 102:62–70. 10.1016/j.tifs.2020.05.018. doi: 10.1016/j.tifs.2020.05.018.
  • Barnkob, L. L., A. Argyraki, P. M. Petersen, and J. Jakobsen. 2016. Investigation of the effect of UV-LED exposure conditions on the production of vitamin D in pig skin. Food Chemistry 212:386–91. doi: 10.1016/j.foodchem.2016.05.155.
  • Barnkob, L. L., P. M. Petersen, J. P. Nielsen, and J. Jakobsen. 2019. Vitamin D enhanced pork from pigs exposed to artificial UVB light in indoor facilities. European Food Research and Technology 245 (2):411–8. doi: 10.1007/s00217-018-3173-6.
  • Benito, P., and D. Miller. 1998. Iron absorption and bioavailability: an updated review. Nutrition Research 18 (3):581–603. 10.1016/S0271-5317(98)00044-X. doi: 10.1016/S0271-5317(98)00044-X.
  • Bennett, L., C. Kersaitis, S. L. Macaulay, G. Münch, G. Niedermayer, J. Nigro, M. Payne, P. Sheean, P. Vallotton, D. Zabaras, et al. 2013. Vitamin D2-enriched button mushroom (Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice. PLoS One 8 (10):e76362. doi: 10.1371/journal.pone.0076362.
  • Bikle, D. 2009. Nonclassic actions of vitamin D. The Journal of Clinical Endocrinology and Metabolism 94 (1):26–34. doi: 10.1210/jc.2008-1454.
  • Bikle, D. D. 2014. Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & Biology 21 (3):319–29. 10.1016/j.chembiol.2013.12.016. doi: 10.1016/j.chembiol.2013.12.016.
  • Bilbao-Sainz, C., B. S. Chiou, T. Williams, D. Wood, W. X. Du, I. Sedej, Z. Ban, V. Rodov, E. Poverenov, Y. Vinokur, et al. 2017. Vitamin D-fortified chitosan films from mushroom waste. Carbohydrate Polymers 167 (1):97–104. doi: 10.1016/j.carbpol.2017.03.010.
  • Binkley, N., D. Gemar, J. Engelke, R. Gangnon, R. Ramamurthy, D. Krueger, and M. K. Drezner. 2011. Evaluation of ergocalciferol or cholecalciferol dosing, 1,600 IU daily or 50,000 IU monthly in older adults. The Journal of Clinical Endocrinology & Metabolism 96 (4):981–8. doi: 10.1210/jc.2010-0015.
  • Bischoff-Ferrari, H. A., B. Dawson-Hughes, E. Stöcklin, E. Sidelnikov, W. C. Willett, J. O. Edel, H. B. Stähelin, S. Wolfram, A. Jetter, J. Schwager, et al. 2012. Oral supplementation with 25(OH)D3 versus vitamin D3: effects on 25(OH)D levels, lower extremity function, blood pressure, and markers of innate immunity. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research 27 (1):160–9. doi: 10.1002/jbmr.551.
  • Black, L. J., K. M. Seamans, K. D. Cashman, and M. Kiely. 2012. An updated systematic review and meta-analysis of the efficacy of vitamin D food fortification. The Journal of Nutrition 142 (6):1102–8. doi: 10.3945/jn.112.158014.
  • Borel, P., D. Caillaud, and N. J. Cano. 2015. Vitamin D bioavailability: state of the art. Critical Reviews in Food Science and Nutrition 55 (9):1193–205. doi: 10.1080/10408398.2012.688897.
  • Bouillon, R., N. M. Van Schoor, E. Gielen, S. Boonen, C. Mathieu, D. Vanderschueren, and P. Lips. 2013. Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine. The Journal of Clinical Endocrinology and Metabolism 98 (8):E1283–304. doi: 10.1210/jc.2013-1195.
  • Bouillon, R., L. Verlinden, and A. Verstuyf. 2016. Is vitamin D2 really bioequivalent to vitamin D3? Endocrinology 157 (9):3384–7. 10.1210/en.2016-1528. doi: 10.1210/en.2016-1528.
  • Bouis, H. E., and A. Saltzman. 2017. Improving nutrition through biofortification: a review of evidence from HarvestPlus, 2003 through 2016. Global Food Security 12:49–58. doi: 10.1016/j.gfs.2017.01.009.
  • Bouvard, V., D. Loomis, K. Z. Guyton, Y. Grosse, F. E. Ghissassi, L. Benbrahim-Tallaa, N. Guha, H. Mattock, and K. Straif. 2015. Carcinogenicity of consumption of red and processed meat. The Lancet. Oncology 16 (16):1599–600. doi: 10.1016/S1470-2045(15)00444-1.
  • Browning, L. C., and A. J. Cowieson. 2014. Vitamin D fortification of eggs for human health. Journal of the Science of Food and Agriculture 94 (7):1389–96. doi: 10.1002/jsfa.6425.
  • Brustad, M., T. Braaten, and E. Lund. 2004. Predictors for cod-liver oil supplement use-the Norwegian women and cancer study. European Journal of Clinical Nutrition 58 (1):128–36. doi: 10.1038/sj.ejcn.1601759.
  • Brustad, M., T. Sandanger, T. Wilsgaard, L. Aksnes, and E. Lund. 2003. Change in plasma levels of vitamin D after consumption of cod-liver and fresh cod-liver oil as part of the traditional north Norwegian fish dish "Mølje. International Journal of Circumpolar Health 62 (1):40–53. doi: 10.3402/ijch.v62i1.17527.
  • Burild, A., H. L. Frandsen, M. Poulsen, and J. Jakobsen. 2015. Tissue content of vitamin D3 and 25-hydroxy vitamin D3 in minipigs after cutaneous synthesis, supplementation and deprivation of vitamin D3. Steroids 98:72–9. doi: 10.1016/j.steroids.2015.02.017.
  • Burild, A., C. Lauridsen, N. Faqir, H. M. Sommer, and J. Jakobsen. 2016. Vitamin D3 and 25-hydroxyvitamin D3 in pork and their relationship to vitamin D status in pigs. Journal of Nutritional Science 5:e3. doi: 10.1017/jns.2015.28.
  • Buttriss, J. L., and S. A. Lanham‐New. 2020. Is a vitamin D fortification strategy needed? Nutrition Bulletin 45 (2):115–22. 10.1111/nbu.12430. doi: 10.1111/nbu.12430.
  • Calvo, M. S., U. S. Babu, L. H. Garthoff, T. O. Woods, M. Dreher, G. Hill, and S. Nagaraja. 2013. Vitamin D2 from light-exposed edible mushrooms is safe, bioavailable and effectively supports bone growth in rats. Osteoporosis International : A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 24 (1):197–207. doi: 10.1007/s00198-012-1934-9.
  • Cardwell, G., J. F. Bornman, A. P. James, and L. J. Black. 2018. A Review of mushrooms as a potential source of dietary vitamin D. Nutrients 10 (10):1498. doi: 10.3390/nu10101498.
  • Cashman, K. D. 2020a. Food-based strategies for prevention of vitamin D deficiency as informed by vitamin D dietary guidelines, and consideration of minimal-risk UVB radiation exposure in future guidelines. Photochemical and Photobiological Sciences 19:800-9. doi: 10.1039/c9pp00462a.
  • Cashman, K. D. 2020b. Vitamin D deficiency: defining, prevalence, causes, and strategies of addressing. Calcified Tissue International 106 (1):14–29. doi: 10.1007/s00223-019-00559-4.
  • Cashman, K. D., K. G. Dowling, Z. Škrabáková, M. Gonzalez-Gross, J. Valtueña, S. De Henauw, L. Moreno, C. T. Damsgaard, K. F. Michaelsen, C. Mølgaard, et al. 2016a. Vitamin D deficiency in Europe: pandemic? The American Journal of Clinical Nutrition 103 (4):1033–44. doi: 10.3945/ajcn.115.120873.
  • Cashman, K. D., S. Duffy, A. Hayes, K. Seamans, J. Kerry, A. Kelly, J. Jakobsen, and J. O'Doherty. 2015. Biofortification of eggs and pork with vitamin D as a means of increasing dietary supply. The FASEB Journal 29 (S1):758–13. doi: 10.1096/fasebj.29.1_supplement.758.13.
  • Cashman, K. D., M. Kiely, K. M. Seamans, and P. Urbain. 2016b. Effect of ultraviolet light–exposed mushrooms on vitamin D status: liquid chromatography–tandem mass spectrometry reanalysis of biobanked sera from a randomized controlled trial and a systematic review plus meta-analysis. The Journal of Nutrition 146 (3):565–75. doi: 10.3945/jn.115.223784.
  • Cashman, K. D., S. M. O'Sullivan, K. Galvin, and M. Ryan. 2020. Contribution of vitamin D2 and D3 and their respective 25-hydroxy metabolites to the total vitamin D content of beef and lamb. Current Developments in Nutrition 4 (7):nzaa112. doi: 10.1093/cdn/nzaa112..
  • Cashman, K. D., K. M. Seamans, A. J. Lucey, E. Stöcklin, P. Weber, M. Kiely, and T. R. Hill. 2012. Relative effectiveness of oral 25-hydroxyvitamin D3 and vitamin D3 in raising wintertime serum 25-hydroxyvitamin D in older adults. The American Journal of Clinical Nutrition 95 (6):1350–6. doi: 10.3945/ajcn.111.031427.
  • Cashman, K. D., E. G. van den Heuvel, R. J. Schoemaker, D. P. Prévéraud, H. M. Macdonald, and J. Arcot. 2017. 25-Hydroxyvitamin D as a biomarker of vitamin D status and its modeling to inform strategies for prevention of vitamin D deficiency within the population. Advances in Nutrition (Bethesda, Md.) 8 (6):947–57. doi: 10.3945/an.117.015578.
  • Cesareo, R., A. Falchetti, R. Attanasio, G. Tabacco, A. M. Naciu, and A. Palermo. 2019. Hypovitaminosis D: is it time to consider the use of calcifediol? Nutrients 11 (5):1016. 10.3390/nu11051016. doi: 10.3390/nu11051016.
  • Chiang, Y. H., S. I. Hwang, and M. F. Holick. 1996. Influence of different time of ultraviolet irradiation on performance and vitamin D3 metabolism in laying hens. Korean Journal of Animal Nutrition & Feedstuffs 20 (6):497–508.
  • Chiang, Y. H., S. I. Hwang, and M. F. Holick. 1997. Effect of vitamin D3 oral dose or ultraviolet irradiation on yolk vitamin D3, plasma minerals, eggshell thickness and intensity in laying hens. Korean Journal of Animal Nutrition & Feedstuffs 21 (6):475–88.
  • Chien, R. C., S.-C. Yang, L. M. Lin, and J. L. Mau. 2017. Anti-inflammatory and antioxidant properties of pulsed light irradiated Lentinula edodes. Journal of Food Processing and Preservation 41 (4):e13045. doi: 10.1111/jfpp.13045.
  • Christakos, S., P. Dhawan, A. Verstuyf, L. Verlinden, and G. Carmeliet. 2016. Vitamin D: Metabolism, molecular mechanism of action, and pleiotropic effects. Physiological Reviews 96 (1):365–408. 10.1152/physrev.00014.2015. doi: 10.1152/physrev.00014.2015.
  • Cianferotti, L., C. Cricelli, J. A. Kanis, R. Nuti, J. Y. Reginster, J. D. Ringe, R. Rizzoli, and M. L. Brandi. 2015. The clinical use of vitamin D metabolites and their potential developments: a position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Endocrine 50 (1):12–26. doi: 10.1007/s12020-015-0606-x.
  • Clausen, I., J. Jakobsen, T. Leth, and L. Ovesen. 2003. Vitamin D3 and 25-hydroxyvitamin D3 in raw and cooked pork cuts. Journal of Food Composition and Analysis 16 (5):575–85. doi: 10.1016/S0889-1575(03)00064-4.
  • Clonan, A., K. E. Roberts, and M. Holdsworth. 2016. Socioeconomic and demographic drivers of red and processed meat consumption: implications for health and environmental sustainability. The Proceedings of the Nutrition Society 75 (3):367–73. 10.1017/S0029665116000100. doi: 10.1017/S0029665116000100.
  • Coates, A. M., S. Sioutis, J. D. Buckley, and P. R. Howe. 2008. Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors. British Journal of Nutrition 101 (4):592–7. doi: 10.1017/S0007114508025063.
  • Cocking, C.,. J. Walton, L. Kehoe, K. D. Cashman, and A. Flynn. 2020. The role of meat in the European diet: current state of knowledge on dietary recommendations, intakes and contribution to energy and nutrient intakes and status. Nutrition Research Reviews 33 (2):181–9. doi: 10.1017/S0954422419000295.
  • Davies, M., E. B. Mawer, and E. L. Krawitt. 1980. Comparative absorption of vitamin D3 and 25-hydroxyvitamin D3 in intestinal disease. Gut 21 (4):287–92. doi: 10.1136/gut.21.4.287.
  • Dawson-Hughes, B., S. S. Harris, N. J. Palermo, L. Ceglia, and H. Rasmussen. 2013. Meal conditions affect the absorption of supplemental vitamin D3 but not the plasma 25-hydroxyvitamin D response to supplementation. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research 28 (8):1778–83. doi: 10.1002/jbmr.1896.
  • Degre, R., and Z. Zhang. 2014. Yeast cell walls comprising vitamin D2, uses thereof and method of producing the same, LALLEMAND Inc. [WO/2014/114342 A1] EP2948004A1 (EU), CA2897551A1 (Canada), filed January 24, 2013, and issued July 31, 2014.
  • Degre, R., Z. Zhang, and G. Edwards. 2008. Novel vitamin D2 yeast preparation, a method for producing the same and the use thereof, LALLEMAND Inc. [1020090106462] US20080138469A1 (US), EP2092055A4 (EU), filed October 26, 2007, and issued October 09, 2009.
  • Drewnowski, A., E. C. Monterrosa, S. de Pee, E. A. Frongillo, and S. Vandevijvere. 2020. Shaping physical, economic, and policy components of the food environment to create sustainable healthy diets. Food and Nutrition Bulletin 41 (2_suppl):74S–86S. doi: 10.1177/0379572120945904.
  • Duffy, S. K., A. K. Kelly, G. Rajauria, and J. V. O'Doherty. 2018a. Biofortification of meat with vitamin D. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources 13 (045):1–11. doi: 10.1079/PAVSNNR201813045.
  • Duffy, S. K., A. K. Kelly, G. Rajauria, J. Jakobsen, L. C. Clarke, F. J. Monahan, K. G. Dowling, G. Hull, K. Galvin, K. D. Cashman, et al. 2018c. The use of synthetic and natural vitamin D sources in pig diets to improve meat quality and vitamin D content. Meat Science 143:60–8. doi: 10.1016/j.meatsci.2018.04.014.
  • Duffy, S. K., G. Rajauria, L. C. Clarke, A. K. Kelly, K. D. Cashman, and J. V. O'Doherty. 2017b. The potential of cholecalciferol and 25-hydroxyvitamin D3 enriched diets in laying hens, to improve egg vitamin D content and antioxidant availability. Innovative Food Science & Emerging Technologies 44:109–16. doi: 10.1016/j.ifset.2017.07.007.
  • Duffy, S. K., J. V. O'Doherty, G. Rajauria, L. C. Clarke, A. Hayes, K. G. Dowling, M. N. O'Grady, J. P. Kerry, J. Jakobsen, K. D. Cashman, et al. 2018b. Vitamin D-biofortified beef: a comparison of cholecalciferol with synthetic versus UVB-mushroom-derived ergosterol as feed source. Food Chemistry 256:18–24. doi: 10.1016/j.foodchem.2018.02.099.
  • Duffy, S. K., J. V. O'Doherty, G. Rajauria, L. C. Clarke, K. D. Cashman, A. Hayes, M. N. O'Grady, J. P. Kerry, and A. K. Kelly. 2017a. Cholecalciferol supplementation of heifer diets increases beef vitamin D concentration and improves beef tenderness. Meat Science 134:103–10. doi: 10.1016/j.meatsci.2017.07.024.
  • EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). 2014. Scientific opinion on the safety of vitamin D-enriched UV-treated baker‘s yeast. EFSA Journal 12 (1):3520. doi: 10.2903/j.efsa.2014.3520.
  • EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). 2010. Scientific Opinion on the substantiation of health claims related to vitamin D and normal function of the immune system and inflammatory response (ID 154, 159), maintenance of normal muscle function (ID 155) and maintenance of normal cardiovascular function (ID 159) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal 8 (2):1468. doi: 10.2903/j.efsa.2010.1468.
  • European Food Safety Authority. 2009. Commission regulation (EC) No 887/2009. Accessed May 06, 2020. https://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:254:0068:0070:EN:PDF.
  • European Food Safety Authority. 2017. Commission implementing regulation (EU) 2017/1492. Accessed May 06, 2020. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32017R1492&from=EN
  • Fairweather-Tait, S. J. 1993. Bioavailability of nutrients. In: Encyclopaedia of food science, food technology and nutrition, ed. R. Macrae, R. K. Robinson and M. J. Sadler, 384–8. London: Academic Press.
  • Federal Department of Home Affairs. 2019. Swiss food composition database (V6.0). Accessed November 03, 2020. https://www.naehrwertdaten.ch/en/.
  • Fernández-García, E., I. Carvajal-Lérida, and A. Pérez-Gálvez. 2009. In vitro bioaccessibility assessment as a prediction tool of nutritional efficiency. Nutrition Research (New York, N.Y.) 29 (11):751–60. doi: 10.1016/j.nutres.2009.09.016.
  • Food and Drug Administration 2012. Food additives permitted for direct addition to food for human consumption; vitamin D2. Accessed May 04, 2020. https://www.federalregister.gov/documents/2012/08/29/2012-21353/food-additives-permitted-for-direct-addition-to-food-for-human-consumption-vitamin-d2.
  • Friedman, M. 2016. Mushroom polysaccharides: chemistry and antiobesity, antidiabetes, anticancer, and antibiotic properties in cells, rodents, and humans. Foods 5 (4):80. doi: 10.3390/foods5040080.
  • Galior, K., S. Grebe, and R. Singh. 2018. Development of vitamin D toxicity from overcorrection of vitamin D deficiency: a review of case reports. Nutrients 10 (8):953. doi: 10.3390/nu10080953.
  • Geng, Y., Q. Ma, Z. Wang, and Y. Guo. 2018. Dietary vitamin D3 supplementation protects laying hens against lipopolysaccharide-induced immunological stress. Nutrition & Metabolism 15 (58):58 doi: 10.1186/s12986-018-0293-8.
  • Glendenning, P., G. T. Chew, H. M. Seymour, M. J. Gillett, P. R. Goldswain, C. A. Inderjeeth, S. D. Vasikaran, M. Taranto, A. A. Musk, and W. D. Fraser. 2009. Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol. Bone 45 (5):870–5. doi: 10.1016/j.bone.2009.07.015.
  • Godber, J. S. 1990. Nutrient bioavailability in humans and experimental animals. Journal of Food Quality 13 (1):21–36. 10.1111/j.1745-4557.1990.tb00003.x. doi: 10.1111/j.1745-4557.1990.tb00003.x.
  • Godfray, H. C., J. R. Beddington, I. R. Crute, L. Haddad, D. Lawrence, J. F. Muir, J. Pretty, S. Robinson, S. M. Thomas, and C. Toulmin. 2010. Food security: the challenge of feeding 9 billion people. Science (New York, N.Y.) 327 (5967):812–8. doi: 10.1126/science.1185383.
  • Graff, I. E., J. Øyen, M. Kjellevold, L. Frøyland, C. G. Gjesdal, B. Almås, G. Rosenlund, and Ø. Lie. 2016. Reduced bone resorption by intake of dietary vitamin D and K from tailor-made Atlantic salmon: a randomized intervention trial. Oncotarget 7 (43):69200–15. doi: 10.18632/oncotarget.10171.
  • Graff, I. E., S. Høie, G. K. Totland, and Ø. Lie. 2002. Three different levels of dietary vitamin D-3 fed to first-feeding fry of Atlantic salmon (Salmo salar L.): effect on growth, mortality, calcium content and bone formation. Aquaculture Nutrition 8 (2):103–11. doi: 10.1046/j.1365-2095.2002.00197.x.
  • Guan, W., J. Zhang, R. Yan, S. Shao, T. Zhou, J. Lei, and Z. Wang. 2016. Effects of UV-C treatment and cold storage on ergosterol and vitamin D2 contents in different parts of white and brown mushroom (Agaricus bisporus). Food Chemistry 210:129–34. doi: 10.1016/j.foodchem.2016.04.023.
  • Guo, J., J. A. Lovegrove, and D. I. Givens. 2018. 25(OH)D3-enriched or fortified foods are more efficient at tackling inadequate vitamin D status than vitamin D3. The Proceedings of the Nutrition Society 77 (3):282–91. doi: 10.1017/S0029665117004062.
  • Guo, J., J. A. Lovegrove, and D. I. Givens. 2019. Food fortification and biofortification as potential strategies for prevention of vitamin D deficiency. Nutrition Bulletin 44 (1):36–42. doi: 10.1111/nbu.12363.
  • Guo, J., K. G. Jackson, C. S. B. Che Taha, Y. Li, D. I. Givens, and J. A. Lovegrove. 2017. A 25-hydroxycholecalciferol-fortified dairy drink is more effective at raising a marker of postprandial vitamin D status than cholecalciferol in men with suboptimal vitamin D status. The Journal of Nutrition 147 (11):2076–82. doi: 10.3945/jn.117.254789.
  • Hammami, M. M., and A. Yusuf. 2017. Differential effects of vitamin D2 and D3 supplements on 25-hydroxyvitamin D level are dose, sex, and time dependent: a randomized controlled trial. BMC Endocrine Disorders 17 (1):12. doi: 10.1186/s12902-017-0163-9.
  • Hammami, M. M., K. Abuhdeeb, S. Hammami, and A. Yusuf. 2019. Vitamin-D2 treatment-associated decrease in 25(OH)D3 level is a reciprocal phenomenon: a randomized controlled trial. BMC Endocrine Disorders 19 (1):8. doi: 10.1186/s12902-019-0337-8.
  • Haug, A., N. F. Nyquist, T. J. Mosti, M. Andersen, and A. T. Høstmark. 2012. Increased EPA levels in serum phospholipids of humans after four weeks daily ingestion of one portion chicken fed linseed and rapeseed oil. Lipids in Health and Disease 11 (1):104. doi: 10.1186/1476-511X-11-104.
  • Hayes, A., and K. D. Cashman. 2017. Food-based solutions for vitamin D deficiency: putting policy into practice and the key role for research. The Proceedings of the Nutrition Society 76 (1):54–63. doi: 10.1017/S0029665116000756.
  • Hayes, A., S. Duffy, M. O'Grady, J. Jakobsen, K. Galvin, J. Teahan-Dillon, J. Kerry, A. Kelly, J. O'Doherty, S. Higgins, et al. 2016. Vitamin D-enhanced eggs are protective of wintertime serum 25-hydroxyvitamin D in a randomized controlled trial of adults. The American Journal of Clinical Nutrition 104 (3):629–37. doi: 10.3945/ajcn.116.132530.
  • Health Canada. 2015. The Canadian nutrient file (CNF). Accessed November 23, 2020. https://www.canada.ca/en/health-canada/services/food-nutrition/healthy-eating/nutrient-data/canadian-nutrient-file-2015-download-files.html.
  • Heaney, R. P., R. R. Recker, J. Grote, R. L. Horst, and L. A. Armas. 2011. Vitamin D3 is more potent than vitamin D2 in humans. The Journal of Clinical Endocrinology & Metabolism 96 (3):E447–52. doi: 10.1210/jc.2010-2230.
  • Hedrén, E., G. Mulokozi, and U. Svanberg. 2002. In vitro accessibility of carotenes from green leafy vegetables cooked with sunflower oil or red palm oil. International Journal of Food Sciences and Nutrition 53 (6):445–53. 10.1080/09637480220164334. doi: 10.1080/09637480220164334.
  • Hilger, J., A. Friedel, R. Herr, T. Rausch, F. Roos, D. A. Wahl, D. D. Pierroz, P. Weber, and K. Hoffmann. 2014. A systematic review of vitamin D status in populations worldwide. The British Journal of Nutrition 111 (1):23–45. doi: 10.1017/S0007114513001840.
  • Hohman, E. E., B. R. Martin, P. J. Lachcik, D. T. Gordon, J. C. Fleet, and C. M. Weaver. 2011. Bioavailability and efficacy of vitamin D2 from UV-irradiated yeast in growing, vitamin D-deficient rats. Journal of Agricultural and Food Chemistry 59 (6):2341–6. doi: 10.1021/jf104679c.
  • Holick, M. F., N. C. Binkley, H. A. Bischoff-Ferrari, C. M. Gordon, D. A. Hanley, R. P. Heaney, M. H. Murad, and C. M. Weaver. 2012. Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. The Journal of Clinical Endocrinology and Metabolism 97 (4):1153–8. 10.1210/jc.2011-2601. doi: 10.1210/jc.2011-2601.
  • Holick, M. F., N. C. Binkley, H. A. Bischoff-Ferrari, C. M. Gordon, D. A. Hanley, R. P. Heaney, M. H. Murad, and C. M. Weaver. 2011. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline. The Journal of Clinical Endocrinology and Metabolism 96 (7):1911–30. 10.1210/jc.2011-0385. doi: 10.1210/jc.2011-0385.
  • Hollis, B. W., B. A. Roos, H. H. Draper, and P. W. Lambert. 1981. Vitamin D and its metabolites in human and bovine milk. The Journal of Nutrition 111 (7):1240–8. doi: 10.1093/jn/111.7.1240.
  • Horvli, O., Ø. Lie, and L. Aksnes. 1998. Tissue distribution of vitamin D3 in Atlantic salmon Salmo salar: effect of dietary level. Aquaculture Nutrition 4 (2):127–31. doi: 10.1046/j.1365-2095.1998.00062.x.
  • Houghton, L. A., and R. Vieth. 2006. The case against ergocalciferol (vitamin D2) as a vitamin supplement. The American Journal of Clinical Nutrition 84 (4):694–7. doi: 10.1093/ajcn/84.4.694.
  • Hu, D., W. Chen, X. Li, T. Yue, Z. Zhang, Z. Feng, C. Li, X. Bu, Q. X. Li, C. Y. Hu, et al. 2020. Ultraviolet irradiation increased the concentration of vitamin D2 and decreased the concentration of ergosterol in shiitake mushroom (Lentinus edodes) and oyster mushroom (Pleurotus ostreatus) powder in ethanol suspension. ACS Omega 5 (13):7361–8. doi: 10.1021/acsomega.9b04321.
  • Huang, G., W. Cai, and B. Xu. 2017. Vitamin D2, ergosterol, and vitamin B2 content in commercially dried mushrooms marketed in China and increased vitamin D2 content following UV-C irradiation. International Journal for Vitamin and Nutrition Research 87 (5-6):1–10. doi: 10.1024/0300-9831/a000294.
  • Huang, S.-J., C.-P. Lin, and S.-Y. Tsai. 2015. Vitamin D2 content and antioxidant properties of fruit body and mycelia of edible mushrooms by UV-B irradiation. Journal of Food Composition and Analysis 42:38–45. 10.1016/j.jfca.2015.02.005. doi: 10.1016/j.jfca.2015.02.005.
  • Institute of Medicine, et al. 2011. Overview of Vitamin D. In Dietary Reference Intakes for Calcium and Vitamin D, ed. A. C. Ross, C. L. Taylor, A. L. Yaktine, Washington (DC): The National Academies Press (US). www.ncbi.nlm.nih.gov/books/NBK56061/.
  • Itkonen, S. T., E. Skaffari, P. Saaristo, E. M. Saarnio, M. Erkkola, J. Jakobsen, K. D. Cashman, and C. Lamberg-Allardt. 2016. Effects of vitamin D2-fortified bread v. supplementation with vitamin D2 or D3 on serum 25-hydroxyvitamin D metabolites: an 8-week randomised-controlled trial in young adult Finnish women. British Journal of Nutrition 115 (7):1232–9. doi: 10.1017/S0007114516000192.
  • Itkonen, S. T., E. T. Pajula, K. G. Dowling, G. L. Hull, K. D. Cashman, and C. J. Lamberg-Allardt. 2018. Poor bioavailability of vitamin D2 from ultraviolet-irradiated D2-rich yeast in rats. Nutrition Research 59:36–43. doi: 10.1016/j.nutres.2018.07.008.
  • Itkonen, S. T., M. Erkkola, and C. Lamberg-Allardt. 2018. Vitamin D fortification of fluid milk products and their contribution to vitamin D intake and vitamin D status in observational studies-A review. Nutrients 10 (8):1054. doi: 10.3390/nu10081054.
  • Itkonen, S. T., R. Andersen, A. K. Björk, Å. Brugård Konde, H. Eneroth, M. Erkkola, K. Holvik, A. A. Madar, H. E. Meyer, I. Tetens, et al. 2020. Vitamin D status and current policies to achieve adequate vitamin D intake in the Nordic countries. Scandinavian Journal of Public Health. Advance online publication doi: 10.1177/1403494819896878.
  • Jackson, M. J. 1997. The assessment of bioavailability of micronutrients: introduction. European Journal of Clinical Nutrition 51 (Suppl 1):S1–S2.
  • Jakobsen, J., A. Melse-Boonstra, and M. Rychlik. 2019. Challenges to quantify total vitamin activity: how to combine the contribution of diverse vitamers? Current Developments in Nutrition 3 (10):nzz086 doi: 10.1093/cdn/nzz086.
  • Jakobsen, J., C. Smith, A. Bysted, and K. D. Cashman. 2019. Vitamin D in wild and farmed Atlantic salmon (Salmo salar)-what do we know? Nutrients 11 (5):982. doi: 10.3390/nu11050982.
  • Jakobsen, J., E. Andersen, T. Christensen, R. Andersen, and S. Bügel. 2017. Vitamin D vitamers affect vitamin D status differently in young healthy males. Nutrients 10 (1):12. 10.3390/nu10010012. doi: 10.3390/nu10010012.
  • Jakobsen, J., H. Maribo, A. Bysted, H. Sommer, and O. Hels. 2007. 25-Hydroxyvitamin D3 affects vitamin D status similar to vitamin D3 in pigs – but the meat produced has a lower content of vitamin D. British Journal of Nutrition 98 (5):908–13. doi: 10.1017/S0007114507756933.
  • Jakobsen, J., S. K. Jensen, L. Hymøller, E. W. Andersen, P. Kaas, A. Burild, and R. B. Jäpelt. 2015. Short communication: artificial ultraviolet B light exposure increases vitamin D levels in cow plasma and milk. Journal of Dairy Science 98 (9):6492–8. doi: 10.3168/jds.2014-9277.
  • Jakobsen, S. S., J. P. Nielsen, and J. Jakobsen. 2020. Effect of UVB light on vitamin D status in piglets and sows. The Journal of Steroid Biochemistry and Molecular Biology 200(:105637. doi: 10.1016/j.jsbmb.2020.105637.
  • Jäpelt, R. B., and J. Jakobsen. 2013. Vitamin D in plants: a review of occurrence, analysis, and biosynthesis. Frontiers in Plant Science 4:136. doi: 10.3389/fpls.2013.00136.
  • Jasinghe, V. J., and C. O. Perera. 2005. Distribution of ergosterol in different tissues of mushrooms and its effect on the conversion of ergosterol to vitamin D2 by UV irradiation. Food Chemistry 92 (3):541–6. doi: 10.1016/j.foodchem.2004.08.022.
  • Jasinghe, V. J., and C. O. Perera. 2006. Ultraviolet irradiation: the generator of vitamin D2 in edible mushrooms. Food Chemistry 95 (4):638–43. doi: 10.1016/j.foodchem.2005.01.046.
  • Jasinghe, V. J., C. O. Perera, and P. J. Barlow. 2006. Vitamin D2 from irradiated mushrooms significantly increases femur bone mineral density in rats. Journal of Toxicology and Environmental Health. Part A 69 (21):1979–85. doi: 10.1080/15287390600751413.
  • Jasinghe, V. J., C. O. Perera, and S. S. Sablani. 2007. Kinetics of the conversion of ergosterol in edible mushrooms. Journal of Food Engineering 79 (3):864–9. doi: 10.1016/j.jfoodeng.2006.01.085.
  • Jetter, A., A. Egli, B. Dawson-Hughes, H. B. Staehelin, E. Stoecklin, R. Goessl, J. Henschkowski, and H. A. Bischoff-Ferrari. 2014. Pharmacokinetics of oral vitamin D3 and calcifediol. Bone 59:14–9. doi: 10.1016/j.bone.2013.10.014.
  • Jha, A. B., and T. D. Warkentin. 2020. Biofortification of pulse crops: status and future perspectives. Plants 9 (1):73. doi: 10.3390/plants9010073.
  • Jones, K. S., S. Assar, D. Harnpanich, R. Bouillon, D. Lambrechts, A. Prentice, and I. Schoenmakers. 2014. 25(OH)D2 half-life is shorter than 25(OH)D3 half-life and is influenced by DBP concentration and genotype. The Journal of Clinical Endocrinology & Metabolism 99 (9):3373–81. doi: 10.1210/jc.2014-1714.
  • Kalaras, M. D., R. B. Beelman, and R. J. Elias. 2012a. Effects of postharvest pulsed UV light treatment of white button mushrooms (Agaricus bisporus) on vitamin D2 content and quality attributes. Journal of Agricultural and Food Chemistry 60 (1):220–5. doi: 10.1021/jf203825e.
  • Kalaras, M. D., R. B. Beelman, M. F. Holick, and R. J. Elias. 2012b. Generation of potentially bioactive ergosterol-derived products following pulsed ultraviolet light exposure of mushrooms (Agaricus bisporus). Food Chemistry 135 (2):396–401. doi: 10.1016/j.foodchem.2012.04.132.
  • Kamweru, P. K., and E. L. Tindibale. 2016. Vitamin D and vitamin D from ultraviolet-irradiated mushrooms (review). International Journal of Medicinal Mushrooms 18 (3):205–14. doi: 10.1615/IntJMedMushrooms.v18.i3.30.
  • Kawazoe, T., K. Yuasa, K. Noguchi, M. Yamazaki, and M. Ando. 1996. Effect of different sources of vitamin D on transfer of vitamin D to egg yolk. Nippon Shokuhin Kagaku Kogaku Kaishi 43 (4):444–50. doi: 10.3136/nskkk.43.444.
  • Kawazoe, T., K. Yuasa, M. Yamazaki, and M. Ando. 1994. Production of Vitamin D-fortified eggs by feeding vitamin D2-fortified shiitake. Nippon Shokuhin Kogyo Gakkaishi 41 (12):891–6. doi: 10.3136/nskkk1962.41.891.
  • Keegan, R. J., Z. Lu, J. M. Bogusz, J. E. Williams, and H. F. Holick. 2013. Photobiology of vitamin D in mushrooms and its bioavailability in humans. Dermato-endocrinology 5 (1):165–76. doi: 10.4161/derm.23321.
  • Ko, J. A., B. H. Lee, J. S. Lee, and H. J. Park. 2008. Effect of UV-B exposure on the concentration of vitamin D2 in sliced shiitake mushroom (Lentinus edodes) and white button mushroom (Agaricus bisporus). Journal of Agricultural and Food Chemistry 56 (10):3671–4. doi: 10.1021/jf073398s.
  • Kohn, J. B. 2016. Are mushrooms a significant source of vitamin D? Journal of the Academy of Nutrition and Dietetics 116 (9):1520. doi: 10.1016/j.jand.2016.07.001.
  • Kolp, E., M. R. Wilkens, W. Pendl, B. Eichenberger, and A. Liesegang. 2017. Vitamin D metabolism in growing pigs: influence of UVB irradiation and dietary vitamin D supply on calcium homeostasis, its regulation and bone metabolism. Journal of Animal Physiology and Animal Nutrition 101 (Suppl 1):79–94. doi: 10.1111/jpn.12707.
  • Korn, K. T., R. P. Lemenager, M. C. Claeys, M. Engstrom, and J. P. Schoonmaker. 2013. Supplemental vitamin D3 and zilpaterol hydrochloride. I. Effect on performance, carcass traits, tenderness, and vitamin D metabolites of feedlot steers. Journal of Animal Science 91 (7):3322–31. doi: 10.2527/jas.2012-5960.
  • Koshy, K. T., and A. L. Van Der Slik. 1979. High-performance liquid chromatographic method for the determination of 25-hydroxycholecalciferol in chicken egg yolks. Journal of Agricultural and Food Chemistry 27 (1):180–3. doi: 10.1021/jf60221a033.
  • Kotta, S., D. Gadhvi, N. Jakeways, M. Saeed, R. Sohanpal, S. Hull, O. Famakin, A. Martineau, and C. Griffiths. 2015. "Test me and treat me"-attitudes to vitamin D deficiency and supplementation: a qualitative study . BMJ Open 5 (7):e007401. doi: 10.1136/bmjopen-2014-007401.
  • Koyyalamudi, S. R., S.-C. Jeong, C.-H. Song, K. Y. Cho, and G. Pang. 2009. Vitamin D2 formation and bioavailability from Agaricus bisporus button mushrooms treated with ultraviolet irradiation. Journal of Agricultural and Food Chemistry 57 (8):3351–5. doi: 10.1021/jf803908q.
  • Koyyalamudi, S. R., S.-C. Jeong, G. Pang, A. Teal, and T. Biggs. 2011. Concentration of vitamin D2 in white button mushrooms (Agaricus bisporus) exposed to pulsed UV light. Journal of Food Composition and Analysis 24 (7):976–9. doi: 10.1016/j.jfca.2011.02.007.
  • Krings, U., and R. G. Berger. 2014. Dynamics of sterols and fatty acids during UV-B treatment of oyster mushroom. Food Chemistry 149:10–4. doi: 10.1016/j.foodchem.2013.10.064.
  • Kristensen, H. L., E. Rosenqvist, and J. Jakobsen. 2012. Increase of vitamin D2 by UV-B exposure during the growth phase of white button mushroom (Agaricus bisporus). Food & Nutrition Research 56 (1):7114. ( doi: 10.3402/fnr.v56i0.7114.
  • Kühn, J., A. Schutkowski, F. Hirche, A. C. Baur, N. Mielenz, and G. I. Stangl. 2015. Non-linear increase of vitamin D content in eggs from chicks treated with increasing exposure times of ultraviolet light. The Journal of Steroid Biochemistry and Molecular Biology 148:7–13. doi: 10.1016/j.jsbmb.2014.10.015.
  • Kühn, J., A. Schutkowski, H. Kluge, F. Hirche, and G. I. Stangl. 2014. Free-range farming: a natural alternative to produce vitamin D-enriched eggs. Nutrition 30 (4):481–4. doi: 10.1016/j.nut.2013.10.002.
  • Kühn, J., C. Wassermann, S. Ebschke, A. Schutkowski, K. Thamm, M. Wensch-Dorendorf, E. von Borell, and G. I. Stangl. 2019. Feasibility of artificial light regimes to increase the vitamin D content in indoor-laid eggs. Poultry Science 98 (10):5177–87. doi: 10.3382/ps/pez234.
  • Larson-Meyer, D. E., B. C. Ingold, S. R. Fensterseifer, K. J. Austin, P. J. Wechsler, B. W. Hollis, A. J. Makowski, and B. M. Alexander. 2017. Sun exposure in pigs increases the vitamin D nutritional quality of pork. PLoS One 12 (11):e0187877. doi: 10.1371/journal.pone.0187877.
  • Lee, G.-S., H.-S. Byun, K.-H. Yoon, J.-S. Lee, K.-C. Choi, and E.-B. Jeung. 2009. Dietary calcium and vitamin D2 supplementation with enhanced Lentinula edodes improves osteoporosis-like symptoms and induces duodenal and renal active calcium transport gene expression in mice. European Journal of Nutrition 48 (2):75–83. doi: 10.1007/s00394-008-0763-2.
  • Lee, N. K., and B. Y. Aan. 2016. Optimization of ergosterol to vitamin D2 synthesis in Agaricus bisporus powder using ultraviolet-B radiation. Food Science and Biotechnology 25 (6):1627–31. doi: 10.1007/s10068-016-0250-0.
  • Leventis, P., and P. D. Kiely. 2009. The tolerability and biochemical effects of high-dose bolus vitamin D2 and D3 supplementation in patients with vitamin D insufficiency. Scandinavian Journal of Rheumatology 38 (2):149–53. doi: 10.1080/03009740802419081.
  • Lietzow, J., H. Kluge, C. Brandsch, N. Seeburg, F. Hirche, M. Glomb, and G. I. Stangl. 2012. Effect of short-term UVB exposure on vitamin D concentration of eggs and vitamin D status of laying hens. Journal of Agricultural and Food Chemistry 60 (3):799–804. doi: 10.1021/jf204273n.
  • Lin, L. Y., L. Smeeth, S. Langan, and C. Warren-Gash. 2021. Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank. BMJ Open 11 (1):e038503. 10.1136/bmjopen-2020-038503. doi: 10.1136/bmjopen-2020-038503.
  • Lipkie, T. E., M. G. Ferruzzi, and C. M. Weaver. 2016. Low bioaccessibility of vitamin D2 from yeast-fortified bread compared to crystalline D2 bread and D3 from fluid milks. Food & Function 7 (11):4589–96. 10.1039/c6fo00935b. doi: 10.1039/C6FO00935B.
  • Logan, V. F., A. R. Gray, M. C. Peddie, M. J. Harper, and L. A. Houghton. 2013. Long-term vitamin D3 supplementation is more effective than vitamin D2 in maintaining serum 25-hydroxyvitamin D status over the winter months. British Journal of Nutrition 109 (6):1082–8. doi: 10.1017/S0007114512002851.
  • Maislos, M., and S. Shany. 1987. Bile salt deficiency and the absorption of vitamin D metabolites. In vivo study in the rat. Israel Journal of Medical Sciences 23 (11):1114–7.
  • Maislos, M.,. J. Silver, and M. Fainaru. 1981. Intestinal absorption of vitamin D sterols: differential absorption into lymph and portal blood in the rat. Gastroenterology 80 (6):1528–34. doi: 10.1016/0016-5085(81)90268-7.
  • Malagoli, M.,. M. Schiavon, S. dall'Acqua, and E. A. Pilon-Smits. 2015. Effects of selenium biofortification on crop nutritional quality. Frontiers in Plant Science 6(:280 doi: 10.3389/fpls.2015.00280.
  • Manson, J. E., N. R. Cook, I. M. Lee, W. Christen, S. S. Bassuk, S. Mora, H. Gibson, D. Gordon, T. Copeland, D. D'Agostino, et al. 2019. Vitamin D supplements and prevention of cancer and cardiovascular disease. The New England Journal of Medicine 380 (1):33–44. doi: 10.1056/NEJMoa1809944.
  • Marangoni, F., G. Corsello, C. Cricelli, N. Ferrara, A. Ghiselli, L. Lucchin, and A. Poli. 2015. Role of poultry meat in a balanced diet aimed at maintaining health and wellbeing: an Italian consensus document. Food & Nutrition Research 59:27606. doi: 10.3402/fnr.v59.27606.
  • Martineau, A. R., K. E. Thummel, Z. Wang, D. A. Jolliffe, B. J. Boucher, S. J. Griffin, N. G. Forouhi, and G. A. Hitman. 2019. Differential effects of oral boluses of vitamin D2 vs vitamin D3 on vitamin D metabolism: a randomized controlled trial. The Journal of Clinical Endocrinology and Metabolism 104 (12):5831–9. doi: 10.1210/jc.2019-00207.
  • Mattila, P. H., E. Valkonen, and J. Valaja. 2011. Effect of different vitamin D supplementations in poultry feed on vitamin D content of eggs and chicken meat. Journal of Agricultural and Food Chemistry 59 (15):8298–303. doi: 10.1021/jf2012634.
  • Mattila, P., J. Valaja, L. Rossow, E. Venäläinen, and T. Tupasela. 2004. Effect of vitamin D2- and D3-enriched diets on egg vitamin D content, production, and bird condition during an entire production period. Poultry Science 83 (3):433–40. doi: 10.1093/ps/83.3.433.
  • Mattila, P., K. Lehikoinen, T. Kiiskinen, and V. Piironen. 1999a. Cholecalciferol and 25-hydroxycholecalciferol content of chicken egg yolk as affected by the cholecalciferol content of feed. Journal of Agricultural and Food Chemistry 47 (10):4089–92. doi: 10.1021/jf990183c.
  • Mattila, P., T. Rokka, K. Könkö, J. Valaja, L. Rossow, and E. L. Ryhänen. 2003. Effect of cholecalciferol-enriched hen feed on egg quality. Journal of Agricultural and Food Chemistry 51 (1):283–7. doi: 10.1021/jf020743z.
  • Mattila, P., V. Piironen, T. Hakkarainen, T. Hirvi, E. Uusi‐Rauva, and P. Eskelinen. 1999b. Possibilities to raise vitamin D content of rainbow trout (Oncorhynchus mykiss) by elevated feed cholecalciferol contents. Journal of the Science of Food and Agriculture 79 (2):195–8. doi: 10.1002/(SICI)1097-0010(199902)79:2 < 195::AID-JSFA166 > 3.0.CO;2-C.
  • Mau, J. L., P.-R. Chen, and J.-H. Yang. 1998. Ultraviolet irradiation increased vitamin D2 content in edible mushrooms. Journal of Agricultural and Food Chemistry 46 (12):5269–72. doi: 10.1021/jf980602q.
  • Maurya, V. K., and M. Aggarwal. 2017. Factors influencing the absorption of vitamin D in GIT: an overview. Journal of Food Science and Technology 54 (12):3753–65. doi: 10.1007/s13197-017-2840-0.
  • Mazahery, H., and P. R. von Hurst. 2015. Factors affecting 25-hydroxyvitamin D concentration in response to vitamin D supplementation. Nutrients 7 (7):5111–42. 10.3390/nu7075111. doi: 10.3390/nu7075111.
  • McAfee, A. J., E. M. McSorley, G. J. Cuskelly, A. M. Fearon, B. W. Moss, J. A. Beattie, J. M. Wallace, M. P. Bonham, and J. J. Strain. 2011. Red meat from animals offered a grass diet increases plasma and platelet n-3 PUFA in healthy consumers. British Journal of Nutrition 105 (1):80–9. doi: 10.1017/S0007114510003090.
  • McDermott, C. M., D. C. Beitz, E. T. Littledike, and R. L. Horst. 1985. Effects of dietary vitamin D3 on concentrations of vitamin D and its metabolites in blood plasma and milk of dairy cows. Journal of Dairy Science 68 (8):1959–67. doi: 10.3168/jds.S0022-0302(85)81057-2.
  • McNeill, S., and M. E. Van Elswyk. 2012. Red meat in global nutrition. Meat Science 92 (3):166–73. doi: 10.1016/j.meatsci.2012.03.014.
  • Mehrotra, A., M. S. Calvo, R. B. Beelman, E. Levy, J. Siuty, M. D. Kalaras, and J. Uribarri. 2014. Bioavailability of vitamin D2 from enriched mushrooms in prediabetic adults: a randomized controlled trial. European Journal of Clinical Nutrition 68 (10):1154–60. 10.1038/ejcn.2014.157. doi: 10.1038/ejcn.2014.157.
  • Melhem, S. J., K. M. Aiedeh, and K. A. Hadidi. 2015. Effects of a 10-day course of a high dose calciferol versus a single mega dose of ergocalciferol in correcting vitamin D deficiency. Annals of Saudi Medicine 35 (1):13–8. doi: 10.5144/0256-4947.2015.13.
  • Mocanu, V., and R. Vieth. 2013. Three-year follow-up of serum 25-hydroxyvitamin D, parathyroid hormone, and bone mineral density in nursing home residents who had received 12 months of daily bread fortification with 125 μg of vitamin D3. Nutrition Journal 12:137. 10.1186/1475-2891-12-137. doi: 10.1186/1475-2891-12-137.
  • Montgomery, J. L., F. C. Parrish, Jr., D. C. Beitz, R. L. Horst, E. J. Huff-Lonergan, and A. H. Trenkle. 2000. The use of vitamin D3 to improve beef tenderness. Journal of Animal Science 78 (10):2615–21. doi: 10.2527/2000.78102615x.
  • Montgomery, J. L., M. A. Carr, C. R. Kerth, G. G. Hilton, B. P. Price, M. L. Galyean, R. L. Horst, and M. F. Miller. 2002. Effect of vitamin D3 supplementation level on the postmortem tenderization of beef from steers. Journal of Animal Science 80 (4):971–81. doi: 10.2527/2002.804971x.
  • Montgomery, J. L., M. B. King, J. G. Gentry, A. R. Barham, B. L. Barham, G. G. Hilton, J. R. Blanton, R. L. Horst, M. L. Galyean, K. J. Morrow, et al. 2004. Supplemental vitamin D3 concentration and biological type of steers. II. Tenderness, quality, and residues of beef. Journal of Animal Science 82 (7):2092–104. doi: 10.2527/2004.8272092x.
  • Mulligan, G. B., and A. Licata. 2010. Taking vitamin D with the largest meal improves absorption and results in higher serum levels of 25-hydroxyvitamin D. Journal of Bone and Mineral Research 25 (4):928–30. doi: 10.1002/jbmr.67.
  • National Food Institute. 2019. Danish food composition databank (version 4). Accessed November 03, 2020. https://frida.fooddata.dk/. Technical University of Denmark.
  • National Nutrition Council. 2010. Valtion ravitsemusneuvottelukunta. D-vitamiinityöryhmän raportti [Report of vitamin D working group]. Accessed May 14, 2021. https://www.ruokavirasto.fi/globalassets/teemat/terveytta-edistava-ruokavalio/ravitsemus–ja-ruokasuositukset/erityisohjeet-ja-rajoitukset/d-vitamiiniraportti2010.pdf.
  • Natri, A.-M., P. Salo, T. Vikstedt, A. Palssa, M. Huttunen, M. U. Kärkkäinen, H. Salovaara, V. Piironen, J. Jakobsen, and C. J. Lamberg-Allardt. 2006. Bread fortified with cholecalciferol increases the serum 25-hydroxyvitamin D concentration in women as effectively as a cholecalciferol supplement. The Journal of Nutrition 136 (1):123–7. 10.1093/jn/136.1.123. doi: 10.1093/jn/136.1.123.
  • Navarro-Valverde, C., M. Sosa-Henríquez, M. R. Alhambra-Expósito, and J. M. Quesada-Gómez. 2016. Vitamin D3 and calcidiol are not equipotent. The Journal of Steroid Biochemistry and Molecular Biology 164:205–8. doi: 10.1016/j.jsbmb.2016.01.014.
  • Nemeth, M. V., M. R. Wilkens, and A. Liesegang. 2017. Vitamin D status in growing dairy goats and sheep: influence of ultraviolet B radiation on bone metabolism and calcium homeostasis. Journal of Dairy Science 100 (10):8072–86. doi: 10.3168/jds.2017-13061.
  • NEVO online version 6.0. 2019. Dutch Food Composition Database. RIVM National Institute for Public Health and the Environment, Bilthoven. Accessed November 23, 2020. https://www.rivm.nl/en/dutch-food-composition-database.
  • Nieman, D. C., N. D. Gillitt, R. A. Shanely, D. Dew, M. P. Meaney, and B. Luo. 2013. Vitamin D2 supplementation amplifies eccentric exercise-induced muscle damage in NASCAR pit crew athletes. Nutrients 6 (1):63–75. doi: 10.3390/nu6010063.
  • Nikooyeh, B., T. R. Neyestani, M. Zahedirad, M. Mohammadi, S. H. Hosseini, Z. Abdollahi, F. Salehi, J. Mirzay Razaz, N. Shariatzadeh, A. Kalayi, et al. 2016. Vitamin D-fortified bread is as effective as supplement in improving vitamin D status: a randomized clinical trial. The Journal of Clinical Endocrinology & Metabolism 101 (6):2511–9. 10.1210/jc.2016-1631. doi: 10.1210/jc.2016-1631.
  • Nimitphong, H., S. Saetung, S. Chanprasertyotin, L. O. Chailurkit, and B. Ongphiphadhanakul. 2013. Changes in circulating 25-hydroxyvitamin D according to vitamin D binding protein genotypes after vitamin D3 or D2 supplementation. Nutrition Journal 12 (1) doi: 10.1186/1475-2891-12-39.
  • Nölle, N.,. D. Argyropoulos, S. Ambacher, J. Müller, and H. K. Biesalski. 2017. Vitamin D2 enrichment in mushrooms by natural or artificial UV-light during drying. LWT - Food Science and Technology 85 (B):400–4. doi: 10.1016/j.lwt.2016.11.072.
  • Nussey, S., and S. Whitehead. 2001. The parathyroid glands and vitamin D. In Endocrinology: an integrated approach. Oxford: BIOS Scientific Publishers. www.ncbi.nlm.nih.gov/books/NBK24/.
  • OECD. 2020. Meat consumption. Accessed April 01, 2020. doi: 10.1787/fa290fd0-en.
  • Oliveri, B., S. R. Mastaglia, G. M. Brito, M. Seijo, G. A. Keller, J. Somoza, R. A. Diez, and G. D. Girolamo. 2015. Vitamin D3 seems more appropriate than D2 to sustain adequate levels of 25OHD: a pharmacokinetic approach. European Journal of Clinical Nutrition 69 (6):697–702. doi: 10.1038/ejcn.2015.16.
  • Park, S. W., H. Namkung, H. J. Ahn, and I. K. Paik. 2005. Enrichment of vitamins D3, K and iron in eggs of laying hens. Asian-Australasian Journal of Animal Sciences 18 (2):226–9. doi.org/ doi: 10.5713/ajas.2005.226.
  • Perera, C. O., V. J. Jasinghe, F. L. Ng, and A. S. Mujumdar. 2003. The effect of moisture content on the conversion of ergosterol to vitamin D in shiitake mushrooms. Drying Technology 21 (6):1091–9. doi: 10.1081/DRT-120021876.
  • Phillips, K. M., and A. S. Rasor. 2013. A nutritionally meaningful increase in vitamin D in retail mushrooms is attainable by exposure to sunlight prior to consumption. Journal of Nutrition and Food Sciences 3 (6) doi: 10.4172/2155-9600.1000236.
  • Phillips, K. M., D. M. Ruggio, R. L. Horst, B. Minor, R. R. Simon, M. J. Feeney, W. C. Byrdwell, and D. B. Haytowitz. 2011. Vitamin D and sterol composition of 10 types of mushrooms from retail suppliers in the United States. Journal of Agricultural and Food Chemistry 59 (14):7841–53. doi: 10.1021/jf104246z.
  • Pierens, S. L., and D. R. Fraser. 2015. The origin and metabolism of vitamin D in rainbow trout. The Journal of Steroid Biochemistry and Molecular Biology 145:58–64. doi: 10.1016/j.jsbmb.2014.10.005.
  • Pilz, S., A. Zittermann, C. Trummer, V. Theiler-Schwetz, E. Lerchbaum, M. H. Keppel, M. R. Grübler, W. März, and M. Pandis. 2019. Vitamin D testing and treatment: a narrative review of current evidence. Endocrine Connections 8 (2):R27–R43. 10.1530/EC-18-0432. doi: 10.1530/EC-18-0432.
  • Pilz, S., W. März, K. D. Cashman, M. E. Kiely, S. J. Whiting, M. F. Holick, W. B. Grant, P. Pludowski, M. Hiligsmann, C. Trummer, et al. 2018. Rationale and plan for vitamin D food fortification: a review and guidance paper. Frontiers in Endocrinology 9:373. doi: 10.3389/fendo.2018.00373.
  • Pittas, A. G., B. Dawson-Hughes, P. Sheehan, J. H. Ware, W. C. Knowler, V. R. Aroda, I. Brodsky, L. Ceglia, C. Chadha, R. Chatterjee., et al. 2019. Vitamin D supplementation and prevention of type 2 diabetes. The New England Journal of Medicine 381 (6):520–30. doi:10.1056/NEJMoa1900906N.
  • Plaimast, H., S. Kijparkorn, and P. Ittitanawong. 2015. Effects of Vitamin D-3 and Calcium on Productive Performance, Egg quality and Vitamin D-3 Content in Egg of Second Production Cycle Hens. The Thai Veterinary Medicine 45 (2):189–95.
  • Public Health England 2018. NDNS results from years 7 and 8 (combined): data tables. Last Modified April 11, 2018. Accessed May 27, 2020. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/699242/NDNS_yr_7_to_8_statistics.xlsx.
  • Public Health England 2019. McCance and Widdowson's composition of foods integrated dataset. Accessed May 05, 2020. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/788485/McCance_Widdowson_Comp_Foods_Integrated_Dataset_User_Guide_2019__1_.pdf.
  • Quesada-Gomez, J. M., and R. Bouillon. 2018. Is calcifediol better than cholecalciferol for vitamin D supplementation? Osteoporosis International : A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 29 (8):1697–711. doi: 10.1007/s00198-018-4520-y.
  • Reeve, L. E., N. A. Jorgensen, and H. F. Deluca. 1982. Vitamin D compounds in cows' milk . The Journal of Nutrition 112 (4):667–72. doi: 10.1093/jn/112.4.667.
  • Roberts, J. S., Teichert, A. A., and T. H. McHugh. 2008. Vitamin D2 formation from post-harvest UV-B treatment of mushrooms (Agaricus bisporus) and retention during storage. Journal of Agricultural and Food Chemistry 56 (12):4541–4. doi: 10.1021/jf0732511.
  • Ruslan, K., R. A. Reza, and S. Damayanti. 2011. Effect of ultraviolet radiation on the formation of ergocalciferol (vitamin D2) in Pleurotus streatus. Bionatura-Jurnal Ilmu-Ilmu Hayati Dan Fisik 13 (3):255–61.
  • Russo, S., L. Carlucci, C. Cipriani, A. Ragno, S. Piemonte, R. D. Fiacco, J. Pepe, V. Fassino, S. Arima, E. Romagnoli, et al. 2011. Metabolic changes following 500 μg monthly administration of calcidiol: a study in normal females. Calcified Tissue International 89 (3):252–7. doi: 10.1007/s00223-011-9513-1.
  • Sandström, B., S. Bügel, C. Lauridsen, F. Nielsen, C. Jensen, and L. H. Skibsted. 2000. Cholesterol-lowering potential in human subjects of fat from pigs fed rapeseed oil. The British Journal of Nutrition 84 (2):143–50. doi: 10.1017/S0007114500001367.
  • Sapozhnikova, Y., W. C. Byrdwell, A. Lobato, and B. Romig. 2014. Effects of UV-B radiation levels on concentrations of phytosterols, ergothioneine, and polyphenolic compounds in mushroom powders used as dietary supplements. Journal of Agricultural and Food Chemistry 62 (14):3034–42. doi: 10.1021/jf403852k.
  • Saternus, R., T. Vogt, and J. Reichrath. 2019. A critical appraisal of strategies to optimize vitamin D status in Germany, a population with a Western diet. Nutrients 11 (11):2682. doi doi: 10.3390/nu11112682.
  • Saura-Calixto, F., J. Serrano, and I. Goñi. 2007. Intake and bioaccessibility of total polyphenols in a whole diet. Food Chemistry 101 (2):492–501. doi: 10.1016/j.foodchem.2006.02.006.
  • Schutkowski, A., J. Kramer, H. Kluge, F. Hirche, A. Krombholz, T. Theumer, and G. I. Stangl. 2013. UVB exposure of farm animals: study on a food-based strategy to bridge the gap between current vitamin D intakes and dietary targets. PLoS One 8 (7):e69418. doi: 10.1371/journal.pone.0069418.
  • Scientific Advisory Committee on Nutrition (SACN). 2010. Iron and Health Report. Accessed August 02, 2019. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/339309/SACN_Iron_and_Health_Report.pdf.
  • Scientific Advisory Committee on Nutrition (SACN). 2016. Vitamin D and Health. Accessed August 19, 2019. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/537616/SACN_Vitamin_D_and_Health_report.pdf.
  • Scragg, R. 2019. Overview of results from the Vitamin D Assessment (ViDA) study. Journal of Endocrinological Investigation 42 (12):1391–9. doi: 10.1007/s40618-019-01056-z.
  • Shanely, R. A., D. C. Nieman, A. M. Knab, N. D. Gillitt, M. P. Meaney, F. Jin, W. Sha, and L. Cialdella-Kam. 2014. Influence of vitamin D mushroom powder supplementation on exercise-induced muscle damage in vitamin D insufficient high school athletes. Journal of Sports Sciences 32 (7):670–9. doi: 10.1080/02640414.2013.847279.
  • Shieh, A., C. Ma, R. F. Chun, S. Witzel, B. Rafison, H. Contreras, J. Wittwer-Schegg, L. Swinkels, T. Huijs, M. Hewison, et al. 2017. Effects of cholecalciferol vs calcifediol on total and free 25-hydroxyvitamin D and parathyroid hormone. The Journal of Clinical Endocrinology & Metabolism 102 (4):1133–40. doi: 10.1210/jc.2016-3919.
  • Shieh, A., R. F. Chun, C. Ma, S. Witzel, B. Meyer, B. Rafison, L. Swinkels, T. Huijs, S. Pepkowitz, B. Holmquist, et al. 2016. Effects of high-dose vitamin D2 versus D3 on total and free 25-hydroxyvitamin D and markers of calcium balance. The Journal of Clinical Endocrinology & Metabolism 101 (8):3070–8. doi: 10.1210/jc.2016-1871.
  • Simon, R. R., K. M. Phillips, R. L. Horst, and I. C. Munro. 2011. Vitamin D mushrooms: comparison of the composition of button mushrooms (Agaricus bisporus) treated postharvest with UVB light or sunlight. Journal of Agricultural and Food Chemistry 59 (16):8724–32. doi: 10.1021/jf201255b.
  • Sioutis, S.,. A. M. Coates, J. D. Buckley, T. W. Murphy, H. A. Channon, and P. R. C. Howe. 2008. N‐3 enrichment of pork with fishmeal: effects on production and consumer acceptability. European Journal of Lipid Science and Technology 110 (8):701–6. doi: 10.1002/ejlt.200700253.
  • Sitrin, M. D., and J. M. Bengoa. 1987. Intestinal absorption of cholecalciferol and 25-hydroxycholecalciferol in chronic cholestatic liver disease. The American Journal of Clinical Nutrition 46 (6):1011–5. doi: 10.1093/ajcn/46.6.1011.
  • Sławińska, A., E. Fornal, W. Radzki, K. Skrzypczak, M. Zalewska-Korona, M. Michalak-Majewska, E. Parfieniuk, and A. Stachniuk. 2016. Study on vitamin D2 stability in dried mushrooms during drying and storage. Food Chemistry 199:203–9. doi: 10.1016/j.foodchem.2015.11.131.
  • Sosa Henríquez, M., and M. J. Gómez de Tejada Romero. 2020. Cholecalciferol or calcifediol in the management of vitamin D deficiency. Nutrients 12 (6):1617. 10.3390/nu12061617. doi: 10.3390/nu12061617.
  • Springmann, M., M. Clark, D. Mason-D'Croz, K. Wiebe, B. L. Bodirsky, L. Lassaletta, W. de Vries, S. J. Vermeulen, M. Herrero, K. M. Carlson, et al. 2018. Options for keeping the food system within environmental limits. Nature 562 (7728):519–25. doi: 10.1038/s41586-018-0594-0.
  • Stephensen, C. B., M. Zerofsky, D. J. Burnett, Y. P. Lin, B. D. Hammock, L. M. Hall, and T. McHugh. 2012. Ergocalciferol from mushrooms or supplements consumed with a standard meal increases 25-hydroxyergocalciferol but decreases 25-hydroxycholecalciferol in the serum of healthy adults. The Journal of Nutrition 142 (7):1246–52. 10.3945/jn.112.159764. doi: 10.3945/jn.112.159764.
  • Stepien, M., L. O'Mahony, A. O'Sullivan, J. Collier, W. D. Fraser, M. J. Gibney, A. P. Nugent, and L. Brennan. 2013. Effect of supplementation with vitamin D2-enhanced mushrooms on vitamin D status in healthy adults. Journal of Nutritional Science 2, e29. doi: 10.1017/jns.2013.22.
  • Taofiq, O., A. Fernandes, A. Barros, M. F. Barreiro, and I. C. F. R. Ferreira. 2017. UV-irradiated mushrooms as a source of vitamin D2: a review. Trends in Food Science & Technology 70:82–94. doi: 10.1016/j.tifs.2017.10.008.
  • Teichmann, A., P. C. Dutta, A. Staffas, and M. Jägerstad. 2007. Sterol and vitamin D2 concentrations in cultivated and wild grown mushrooms: effects of UV irradiation. LWT - Food Science and Technology 40 (5):815–22. doi: 10.1016/j.lwt.2006.04.003.
  • Terry, M., M. Lanenga, J. L. McNaughton, and L. E. Stark. 1999. Safety of 25-hydroxyvitamin D3 as a source of vitamin D3 in layer poultry feed. Veterinary and Human Toxicology 41 (5):312–6.
  • Tripkovic, L., H. Lambert, K. Hart, C. P. Smith, G. Bucca, S. Penson, G. Chope, E. Hyppönen, J. Berry, R. Vieth, et al. 2012. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. The American Journal of Clinical Nutrition 95 (6):1357–64. doi: 10.3945/ajcn.111.031070.
  • U.S. Department of Agriculture (USDA), Agricultural Research Service. 2019. FoodData Central. Accessed November 03, 2020. https://ndb.nal.usda.gov/ndb/foods/show/112.
  • Urbain, P., and J. Jakobsen. 2015. Dose-response effect of sunlight on vitamin D2 production in Agaricus bisporus mushrooms. Journal of Agricultural and Food Chemistry 63 (37):8156–61. doi: 10.1021/acs.jafc.5b02945.
  • Urbain, P., F. Singler, G. Ihorst, H. K. Biesalski, and H. Bertz. 2011. Bioavailability of vitamin D2 from UV-B-irradiated button mushrooms in healthy adults deficient in serum 25-hydroxyvitamin D: a randomized controlled trial. European Journal of Clinical Nutrition 65 (8):965–71. doi: 10.1038/ejcn.2011.53.
  • Urbain, P., J. Valverde, and J. Jakobsen. 2016. Impact on vitamin D2, vitamin D4 and agaritine in Agaricus bisporus mushrooms after artificial and natural solar UV light exposure. Plant Foods for Human Nutrition 71 (3):314–21. doi: 10.1007/s11130-016-0562-5.
  • Vaes, A., M. Tieland, M. F. de Regt, J. Wittwer, L. van Loon, and L. de Groot. 2018. Dose-response effects of supplementation with calcifediol on serum 25-hydroxyvitamin D status and its metabolites: a randomized controlled trial in older adults. Clinical Nutrition 37 (3):808–14. doi: 10.1016/j.clnu.2017.03.029.
  • Vielma, J., S. P. Lall, J. Koskela, F.-J. Schöner, and P. Mattila. 1998. Effects of dietary phytase and cholecalciferol on phosphorus bioavailability in rainbow trout (Oncorhynchus mykiss). Aquaculture 163 (3-4):309–23. doi: 10.1016/S0044-8486(98)00240-3.
  • Wacker, M., and M. F. Holick. 2013. Sunlight and Vitamin D: a global perspective for health. Dermato-endocrinology 5 (1):51–108. doi: 10.4161/derm.24494.
  • Weiss, W. P., E. Azem, W. Steinberg, and T. A. Reinhardt. 2015. Effect of feeding 25-hydroxyvitamin D3 with a negative cation-anion difference diet on calcium and vitamin D status of periparturient cows and their calves. Journal of Dairy Science 98 (8):5588–600. doi: 10.3168/jds.2014-9188.
  • Wen, J., K. A. Livingston, and M. E. Persia. 2019. Effect of high concentrations of dietary vitamin D3 on pullet and laying hen performance, skeleton health, eggshell quality, and yolk vitamin D3 content when fed to W36 laying hens from day of hatch until 68 wk of age. Poultry Science 98 (12):6713–20. doi: 10.3382/ps/pez386.
  • Wetmore, J. B., C. Kimber, J. D. Mahnken, and J. R. Stubbs. 2016. Cholecalciferol v. ergocalciferol for 25-hydroxyvitamin D (25(OH)D) repletion in chronic kidney disease: a randomised clinical trial. British Journal of Nutrition 116 (12):2074–81. doi: 10.1017/S000711451600427X.
  • Wilborn, B. S., C. R. Kerth, W. F. Owsley, W. R. Jones, and L. T. Frobish. 2004. Improving pork quality by feeding supranutritional concentrations of vitamin D3. Journal of Animal Science 82 (1):218–24. doi: 10.2527/2004.821218x.
  • Willett, W.,. J. Rockström, B. Loken, M. Springmann, T. Lang, S. Vermeulen, T. Garnett, D. Tilman, F. DeClerck, A. Wood, et al. 2019. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. Lancet (London, England) 393 (10170):447–92. doi: 10.1016/S0140-6736(18)31788-4.
  • Williams, P. 2007. Nutritional composition of red meat. Nutrition & Dietetics 64 (s4 The Role of):S113–S9. doi: 10.1111/j.1747-0080.2007.00197.x.
  • Wilson, L. R., L. Tripkovic, K. H. Hart, and S. A. Lanham-New. 2017. Vitamin D deficiency as a public health issue: using vitamin D2 or vitamin D3 in future fortification strategies. The Proceedings of the Nutrition Society 76 (3):392–9. doi: 10.1017/S0029665117000349.
  • Wittig, M., U. Krings, and R. G. Berger. 2013. Single-run analysis of vitamin D photoproducts in oyster mushroom (Pleurotus ostreatus) after UV-B treatment. Journal of Food Composition and Analysis 31 (2):266–74. doi: 10.1016/j.jfca.2013.05.017.
  • Won, D. J., S. Y. Kim, C. H. Jang, J. S. Lee, J. A. Ko, and H. J. Park. 2018. Optimization of UV irradiation conditions for the vitamin D2-fortified shiitake mushroom (Lentinula edodes) using response surface methodology. Food Science and Biotechnology 27 (2):417–24. doi: 10.1007/s10068-017-0266-0.
  • World Cancer Research Fund. 2018. Diet, nutrition, physical activity and cancer: a global perspective. Accessed June 15, 2020. www.dietandcancerreport.org.
  • Wu, W. J., and B. Y. Ahn. 2014. Statistical optimization of ultraviolet irradiate conditions for vitamin D2 synthesis in oyster mushrooms (Pleurotus ostreatus) using response surface methodology. PLoS One 9 (4):e95359 doi: 10.1371/journal.pone.0095359.
  • Yao, L., T. Wang, M. Persia, R. L. Horst, and M. Higgins. 2013. Effects of vitamin D(3) -enriched diet on egg yolk vitamin D(3) content and yolk quality . Journal of food science78 (2):C178–83. doi: 10.1111/1750-3841.12032.
  • Zhang, Y., W.-J. Wu, G.-S. Song, and B.-Y. Ahn. 2015. Optimization of ultraviolet irradiate conditions for vitamin D2 synthesis in shitake mushrooms (Lentinula Edodes) by using response surface methodology. Journal of Applied Biological Chemistry 58 (1):25–9. doi: 10.3839/jabc.2015.006.