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Review Articles

Clinical and nutritional management of very-low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: a practical guide for the nutritionist

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Pages 10775-10791 | Published online: 02 Jun 2022

References

  • Adawi, M., G. Damiani, N. L. Bragazzi, C. Bridgewood, A. Pacifico, R. R. Z. Conic, A. Morrone, P. Malagoli, P. D. M. Pigatto, H. Amital, et al. 2019. The impact of intermittent fasting (Ramadan fasting) on psoriatic arthritis disease activity, enthesitis, and dactylitis: A multicentre study. Nutrients 11 (3):601. doi: 10.3390/nu11030601.
  • Afifi, L., M. J. Danesh, K. M. Lee, K. Beroukhim, B. Farahnik, R. S. Ahn, D. Yan, R. K. Singh, M. Nakamura, J. Koo, et al. 2017. Dietary behaviors in psoriasis: Patient-reported outcomes from a U.S. National Survey. Dermatology and Therapy 7 (2):227–42. doi: 10.1007/s13555-017-0183-4.
  • Alotaibi, H. A. 2018. Effects of weight loss on psoriasis: A review of clinical trials. Cureus 10 (10):e3491. doi: 10.7759/cureus.3491.
  • Armstrong, A., S. Jarvis, W. H. Boehncke, M. Rajagopalan, P. Fernández-Peñas, R. Romiti, A. Bewley, B. Vaid, L. Huneault, T. Fox, et al. 2018. Patient perceptions of clear/almost clear skin in moderate-to-severe plaque psoriasis: Results of the Clear About Psoriasis worldwide survey. Journal of the European Academy of Dermatology and Venereology 32 (12):2200–7. doi: 10.1111/jdv.15065.
  • Balato, N., M. Megna, F. Palmisano, C. Patruno, M. Napolitano, M. Scalvenzi, and F. Ayala. 2015. Psoriasis and sport: A new ally? Journal of the European Academy of Dermatology and Venereology 29 (3):515–20. doi: 10.1111/jdv.12607.
  • Barrea, L., M. C. Savanelli, C. Di Somma, M. Napolitano, M. Megna, A. Colao, and S. Savastano. 2017. Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist. Reviews in Endocrine & Metabolic Disorders 18 (2):195–205. doi: 10.1007/s11154-017-9411-6. PMID: 28176237
  • Barrea, L., G. Annunziata, G. Muscogiuri, C. Di Somma, D. Laudisio, M. Maisto, G. de Alteriis, G. C. Tenore, A. Colao, and S. Savastano. 2018. Trimethylamine-N-oxide (TMAO) as novel potential biomarker of early predictors of metabolic syndrome. Nutrients 10 (12):1971. doi: 10.3390/nu10121971.
  • Barrea, L., G. Annunziata, G. Muscogiuri, D. Laudisio, C. Di Somma, M. Maisto, G. C. Tenore, A. Colao, and S. Savastano. 2019. Trimethylamine N-oxide, Mediterranean diet, and nutrition in healthy, normal-weight adults: Also a matter of sex? Nutrition 62:7–17. doi: 10.1016/j.nut.2018.11.015.
  • Barrea, L., N. Balato, C. Di Somma, P. E. Macchia, M. Napolitano, M. C. Savanelli, K. Esposito, A. Colao, and S. Savastano. 2015. Nutrition and psoriasis: Is there any association between the severity of the disease and adherence to the Mediterranean diet? Journal of Translational Medicine 13 (1):18. doi: 10.1186/s12967-014-0372-1.
  • Barrea, L., M. Donnarumma, S. Cacciapuoti, G. Muscogiuri, L. De Gregorio, C. Blasio, S. Savastano, A. Colao, and G. Fabbrocini. 2021. Phase angle and mediterranean diet in patients with acne: Two easy tools for assessing the clinical severity of disease. Journal of Translational Medicine 19 (1):171–185. doi: 10.1186/s12967-021-02826-1.
  • Barrea, L., G. Fabbrocini, G. Annunziata, G. Muscogiuri, M. Donnarumma, C. Marasca, A. Colao, and S. Savastano. 2018. Role of nutrition and adherence to the mediterranean diet in the multidisciplinary approach of hidradenitis suppurativa: Evaluation of nutritional status and its association with severity of disease. Nutrients 11 (1):57. doi: 10.3390/nu11010057.
  • Barrea, L., P. E. Macchia, G. Tarantino, C. Di Somma, E. Pane, N. Balato, M. Napolitano, A. Colao, and S. Savastano. 2015. Nutrition: A key environmental dietary factor in clinical severity and cardio-metabolic risk in psoriatic male patients evaluated by 7-day food-frequency questionnaire. Journal of Translational Medicine 13 (1):303. doi: 10.1186/s12967-015-0658-y.
  • Barrea, L., P. Marzullo, G. Muscogiuri, C. Di Somma, M. Scacchi, F. Orio, G. Aimaretti, A. Colao, and S. Savastano. 2018. Source and amount of carbohydrate in the diet and inflammation in women with polycystic ovary syndrome. Nutrition Research Reviews 31 (2):291–301. doi: 10.1017/S0954422418000136.
  • Barrea, L., M. Megna, S. Cacciapuoti, E. Frias-Toral, G. Fabbrocini, S. Savastano, A. Colao, and G. Muscogiuri. 2022. Very low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: An update for dermatologists and nutritionists. In Critical Reviews in Food Science and Nutrition 62 (2):398–414. doi: 10.1080/10408398.2020.1818053.
  • Barrea, L., G. Muscogiuri, E. Frias-Toral, D. Laudisio, G. Pugliese, B. Castellucci, E. Garcia-Velasquez, S. Savastano, and A. Colao. 2021. Nutrition and immune system: From the Mediterranean diet to dietary supplementary through the microbiota. Critical Reviews in Food Science and Nutrition 61 (18):3066–25. doi: 10.1080/10408398.2020.1792826.
  • Barrea, L., G. Muscogiuri, G. Pugliese, G. de Alteriis, M. Maisto, M. Donnarumma, G. C. Tenore, A. Colao, G. Fabbrocini, and S. Savastano. 2021. Association of Trimethylamine N-Oxide (TMAO) with the Clinical Severity of Hidradenitis Suppurativa (Acne Inversa). Nutrients 13 (6):1997. doi: 10.3390/nu13061997.
  • Barrea, L., F. Nappi, C. Di Somma, M. C. Savanelli, A. Falco, A. Balato, N. Balato, and S. Savastano. 2016. Environmental risk factors in psoriasis: The point of view of the nutritionist. International Journal of Environmental Research and Public Health 13 (7):743. doi: 10.3390/ijerph13070743.
  • Basciani, S., E. Camajani, S. Contini, A. Persichetti, R. Risi, L. Bertoldi, L. Strigari, G. Prossomariti, M. Watanabe, S. Mariani, et al. 2020. Very-low-calorie ketogenic diets with whey, vegetable, or animal protein in patients with obesity: A randomized pilot study. Journal of Clinical Endocrinology and Metabolism. 105 (9):2939–49. doi: 10.1210/clinem/dgaa336.
  • Benhadou, F., D. Mintoff, B. Schnebert, and H. B. Thio. 2018. Psoriasis and Microbiota: A Systematic Review. Diseases (Basel, Switzerland) 6 (2):47. doi: 10.3390/diseases6020047.
  • Bhatia, B. K., J. W. Millsop, M. Debbaneh, J. Koo, E. Linos, and W. Liao. 2014. Diet and psoriasis, part II: Celiac disease and role of a gluten-free diet. Journal of the American Academy of Dermatology 71 (2):350–8. doi: 10.1016/j.jaad.2014.03.017.
  • Bruci, A., D. Tuccinardi, R. Tozzi, A. Balena, S. Santucci, R. Frontani, S. Mariani, S. Basciani, G. Spera, L. Gnessi, et al. 2020. Very low-calorie ketogenic diet: A safe and effective tool for weight loss in patients with obesity and mild kidney failure. Nutrients 12 (2):333. doi: 10.3390/nu12020333.
  • Bueno, N. B., I. S. V. De Melo, S. L. De Oliveira, and T. Da Rocha Ataide. 2013. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: A meta-analysis of Randomised controlled trials. British Journal of Nutrition 110 (7):1178–87. doi: 10.1017/S0007114513000548.
  • Campbell, J. P., and J. E. Turner. 2018. Debunking the myth of exercise-induced immune suppression: Redefining the impact of exercise on immunological health across the lifespan. Frontiers in Immunology 9:648. doi: 10.3389/fimmu.2018.00648.
  • Caprio, M., M. Infante, E. Moriconi, A. Armani, A. Fabbri, G. Mantovani, S. Mariani, C. Lubrano, E. Poggiogalle, S. Migliaccio, the Cardiovascular Endocrinology Club of the Italian Society of Endocrinology, et al. 2019. Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: Systematic review and consensus statement from the Italian Society of Endocrinology (SIE). Journal of Endocrinological Investigation 42 (11):1365–86. doi: 10.1007/s40618-019-01061-2.
  • Castaldo, G., I. Pagano, M. Grimaldi, C. Marino, P. Molettieri, A. Santoro, I. Stillitano, R. Romano, P. Montoro, A. M. D’Ursi, et al. 2021. Effect of very-low-calorie ketogenic diet on psoriasis patients: A nuclear magnetic resonance-based metabolomic study. Journal of Proteome Research 20 (3):1509–21. doi: 10.1021/acs.jproteome.0c00646.
  • Castaldo, G., G. Galdo, F. Rotondi Aufiero, and E. Cereda. 2016. Very low-calorie ketogenic diet may allow restoring response to systemic therapy in relapsing plaque psoriasis. Obesity Research and Clinical Practice 10 (3):348–52. doi: 10.1016/j.orcp.2015.10.008. PMID: 26559897
  • Castaldo, G., L. Rastrelli, G. Galdo, P. Molettieri, F. Rotondi Aufiero, and E. Cereda. 2020. Aggressive weight-loss program with a ketogenic induction phase for the treatment of chronic plaque psoriasis: A proof-of-concept, single-arm, open-label clinical trial. Nutrition 74:110757. doi: 10.1016/j.nut.2020.110757.
  • Castellana, M., E. Conte, A. Cignarelli, S. Perrini, A. Giustina, L. Giovanella, F. Giorgino, and P. Trimboli. 2020. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis. Reviews in Endocrine and Metabolic Disorders. 21 (1):5–16. doi: 10.1007/s11154-019-09514-y.
  • Chapman, S. A., G. P. Wacksman, and B. D. Patterson. 2001. Pancreatitis associated with valproic acid: A review of the literature. Pharmacotherapy 21 (12):1549–60. doi: 10.1592/phco.21.20.1549.34480.
  • Cryan, J. F., and S. M. O’Mahony. 2011. The microbiome-gut-brain axis: From bowel to behavior. Neurogastroenterology and Motility: The Official Journal of the European Gastrointestinal Motility Society 23 (3):187–92. doi: 10.1111/j.1365-2982.2010.01664.x.
  • Custurone, P. Macca, L. Bertino, L. Mauro, D. Di, Trimarchi, F. Vaccaro, M, and Borgia, F. 2021. Mutual influence of psoriasis and sport. Medicina. 57 (2):161–172. doi: 10.3390/medicina57020161.
  • da Silveira, M. P. K. K. da Silva Fagundes, M. R. Bizuti, É. Starck, R. C. Rossi, and D. T. de Resende e Silva. 2021. Physical exercise as a tool to help the immune system against COVID-19: An integrative review of the current literature. Clinical and Experimental Medicine. 21 (1):15–28. doi: 10.1007/s10238-020-00650-3. PMID: 32728975
  • Damiani, G., N. L. Bragazzi, T. S. McCormick, P. D. M. Pigatto, S. Leone, A. Pacifico, D. Tiodorovic, S. Di Franco, A. Alfieri, and M. Fiore. 2020. Gut microbiota and nutrient interactions with skin in psoriasis: A comprehensive review of animal and human studies. World Journal of Clinical Cases 8 (6):1002–12. doi: 10.12998/wjcc.v8.i6.1002.
  • Damiani, G., A. Watad, C. Bridgewood, P. D. M. Pigatto, A. Pacifico, P. Malagoli, N. L. Bragazzi, and M. Adawi. 2019. The impact of ramadan fasting on the reduction of PASI score, in moderate-to-severe psoriatic patients: A real-life multicenter study. Nutrients 11 (2):277. doi: 10.3390/nu11020277.
  • de Heredia, F. P., S. Gómez-Martínez, and A. Marcos. 2012. Obesity, inflammation and the immune system. Proceedings of the Nutrition Society 71 (2):332–8. doi: 10.1017/S0029665112000092.
  • de Luis, D., J. C. Domingo, O. Izaola, F. F. Casanueva, D. Bellido, and I. Sajoux. 2016. Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: A randomized clinical trial. Endocrine 54 (1):111–22. doi: 10.1007/s12020-016-0964-z.
  • Di Rosa, C., G. Lattanzi, S. F. Taylor, S. Manfrini, and Y. M. Khazrai. 2020. Very low calorie ketogenic diets in overweight and obesity treatment: Effects on anthropometric parameters, body composition, satiety, lipid profile and microbiota. Obesity Research and Clinical Practice. 14 (6):491–503. doi: 10.1016/j.orcp.2020.08.009. PMID: 32919928
  • DiPietro, L., S. S. Al-Ansari, S. J. H. Biddle, K. Borodulin, F. C. Bull, M. P. Buman, G. Cardon, C. Carty, J. P. Chaput, S. Chastin, et al. 2020. Advancing the global physical activity agenda: Recommendations for future research by the 2020 WHO physical activity and sedentary behavior guidelines development group. International Journal of Behavioral Nutrition and Physical Activity 17 (1):143–154. doi: 10.1186/s12966-020-01042-2. PMC: 33239105
  • Ford, A. R., M. Siegel, J. Bagel, K. M. Cordoro, A. Garg, A. Gottlieb, L. J. Green, J. E. Gudjonsson, J. Koo, M. Lebwohl, et al. 2018. Dietary recommendations for adults with psoriasis or psoriatic arthritis from the medical board of the national psoriasis foundation a systematic review. JAMA Dermatology 154 (8):934. doi: 10.1001/jamadermatol.2018.1412.
  • Frankel, H. C., J. Han, T. Li, and A. A. Qureshi. 2012. The association between physical activity and the risk of incident psoriasis. Archives of Dermatology 148 (8):918–24. doi: 10.1001/archdermatol.2012.943.
  • Furman, D., J. Campisi, E. Verdin, P. Carrera-Bastos, S. Targ, C. Franceschi, L. Ferrucci, D. W. Gilroy, A. Fasano, G. W. Miller, et al. 2019. Chronic inflammation in the etiology of disease across the life span. Nature Medicine 25 (12):1822–32. doi: 10.1038/s41591-019-0675-0.
  • Garbicz, J., B. Całyniuk, M. Górski, M. Buczkowska, M. Piecuch, A. Kulik, and P. Rozentryt. 2021. Nutritional therapy in persons suffering from psoriasis. Nutrients 14 (1):119. doi: 10.3390/nu14010119.
  • Gentile, C. L., and T. L. Weir. 2018. The gut microbiota at the intersection of diet and human health. Science 362 (6416):776–80. doi: 10.1126/science.aau5812.
  • Goday, A., D. Bellido, I. Sajoux, A. B. Crujeiras, B. Burguera, P. P. García-Luna, A. Oleaga, B. Moreno, and F. F. Casanueva. 2016. Short-Term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus. Nutrition and Diabetes. 6 (9):e230–237. doi: 10.1038/nutd.2016.36.
  • Gomez-Arbelaez, D., D. Bellido, A. I. Castro, L. Ordonez-Mayan, J. Carreira, C. Galban, M. A. Martinez-Olmos, A. B. Crujeiras, I. Sajoux, and F. F. Casanueva. 2017. Body composition changes after very-low-calorie ketogenic diet in obesity evaluated by 3 standardized methods. Journal of Clinical Endocrinology and Metabolism. 102 (2):488–98. doi: 10.1210/jc.2016-2385. PMID:27754807
  • Greb, J. E., A. M. Goldminz, J. T. Elder, M. G. Lebwohl, D. D. Gladman, J. J. Wu, N. N. Mehta, A. Y. Finlay, and A. B. Gottlieb. 2016. Psoriasis. Nature Reviews. Nature Reviews. Disease Primers 2:16082. doi: 10.1038/nrdp.2016.82.
  • Hawkes, J. E., T. C. Chan, and J. G. Krueger. 2017. Psoriasis pathogenesis and the development of novel targeted immune therapies. The Journal of Allergy and Clinical Immunology 140 (3):645–53. doi: 10.1016/j.jaci.2017.07.004.
  • Hills, R. D., B. A. Pontefract, H. R. Mishcon, C. A. Black, S. C. Sutton, and C. R. Theberge. 2019. Gut microbiome: Profound implications for diet and disease. Nutrients 11 (7):1613. doi: 10.3390/nu11071613.
  • Hui, D. Y. 2016. Intestinal phospholipid and lysophospholipid metabolism in cardiometabolic disease. Current Opinion in Lipidology 27 (5):507–12. doi: 10.1097/MOL.0000000000000334.
  • Hwang, J., J. A. Yoo, H. Yoon, T. Han, J. Yoon, S. An, J. Y. Cho, and J. Lee. 2021. The role of leptin in the association between obesity and psoriasis. Biomolecules and Therapeutics 29 (1):11–21. doi: 10.4062/biomolther.2020.054. PMID:32690821
  • Johansson, K., J. Sundström, C. Marcus, E. Hemmingsson, and M. Neovius. 2014. Risk of symptomatic gallstones and cholecystectomy after a very-low-calorie diet or low-calorie diet in a commercial weight loss program: 1-year matched cohort study. International Journal of Obesity 38 (2):279–84. doi: 10.1038/ijo.2013.83.
  • Katsimbri, P., E. Korakas, A. Kountouri, I. Ikonomidis, E. Tsougos, D. Vlachos, E. Papadavid, A. Raptis, and V. Lambadiari. 2021. The effect of antioxidant and anti-inflammatory capacity of diet on psoriasis and psoriatic arthritis phenotype: Nutrition as therapeutic tool? Antioxidants 10 (2):157. doi: 10.3390/antiox10020157.
  • Kim, W. B., D. Jerome, and J. Yeung. 2017. Diagnosis and management of psoriasis. Canadian Family Physician Medecin de Famille Canadien 63 (4):278–85.
  • Kirkpatrick, C. F., J. P. Bolick, P. M. Kris-Etherton, G. Sikand, K. E. Aspry, D. E. Soffer, K. E. Willard, and K. C. Maki. 2019. Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the Nati. Journal of Clinical Lipidology 13 (5):689–711. doi: 10.1016/j.jacl.2019.08.003.
  • Korman, N. J. 2020. Management of psoriasis as a systemic disease: What is the evidence? In. British Journal of Dermatology 182 (4):840–8. doi: 10.1111/bjd.18245.
  • Kyriakou, A., A. Patsatsi, D. Sotiriadis, and D. G. Goulis. 2017. Serum leptin, resistin, and adiponectin concentrations in psoriasis: A meta-analysis of observational studies. Dermatology 233 (5):378–89. doi: 10.1159/000481882.
  • Leeds, A. R. 2014. Formula food-reducing diets:A new evidence-based addition to the weight management tool box. Nutrition Bulletin 39 (3):238–46. doi: 10.1111/nbu.12098.
  • Legat, F. J. 2018. The Antipruritic Effect of Phototherapy. Frontiers in Medicine 5:333. doi: 10.3389/fmed.2018.00333.
  • Lindefeldt, M., A. Eng, H. Darban, A. Bjerkner, C. K. Zetterström, T. Allander, B. Andersson, E. Borenstein, M. Dahlin, and S. Prast-Nielsen. 2019. The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy. NPJ Biofilms and Microbiomes 5 (1):5. doi: 10.1038/s41522-018-0073-2.
  • Luca, M., M. Di Mauro, M. Di Mauro, and A. Luca. 2019. Gut microbiota in Alzheimer’s disease, depression, and type 2 diabetes mellitus: The role of oxidative stress. Oxidative Medicine and Cellular Longevity 2019:4730539. doi: 10.1155/2019/4730539.
  • Magne, F., M. Gotteland, L. Gauthier, A. Zazueta, S. Pesoa, P. Navarrete, and R. Balamurugan. 2020. The firmicutes/bacteroidetes ratio: A relevant marker of gut dysbiosis in obese patients? Nutrients 12 (5):1474. doi: 10.3390/nu12051474.
  • Mazzocchi, A., L. Leone, C. Agostoni, and I. Pali-Schöll. 2019. The secrets of the mediterranean diet. Does [only] olive oil matter? Nutrients 11 (12):2941. doi: 10.3390/nu11122941.
  • Mazzucca, C. B., D. Raineri, G. Cappellano, and A. Chiocchetti. 2021. How to tackle the relationship between autoimmune diseases and diet: Well begun is half-done. Nutrients 13 (11):3956. doi: 10.3390/nu13113956.
  • Megna, M., A. Lobasso, M. Napolitano, F. W. Rossi, A. Balato, C. Matucci-Cerinic, F. Braconaro, F. Prignano, G. Monfrecola, N. Balato, et al. 2017. Soccer helps in controlling the development of psoriasis in Italian second league players. Journal of the European Academy of Dermatology and Venereology 31 (4):e212–e214. doi: 10.1111/jdv.13971.
  • Megna, M., M. Ferrillo, L. Barrea, C. Patruno, G. Muscogiuri, S. Savastano, G. Fabbrocini, and M. Napolitano. 2020. Vitamin D and psoriasis: An update for dermatologists and nutritionists. Minerva Endocrinologica. 45 (2):138–47. doi: 10.23736/S0391-1977.20.03190-9.
  • Merra, G., S. Gratteri, A. De Lorenzo, S. Barrucco, M. A. Perrone, E. Avolio, S. Bernardini, M. Marchetti, and L. Di Renzo. 2017. Effects of very-low-calorie diet on body composition, metabolic state, and genes expression: A randomized double-blind placebo-controlled trial. European Review for Medical and Pharmacological Sciences 21 (2):329–45.
  • Merra, G., R. Miranda, S. Barrucco, P. Gualtieri, M. Mazza, E. Moriconi, M. Marchetti, T. F. M. Chang, A. De Lorenzo, and L. Di Renzo. 2016. Very-low-calorie ketogenic diet with aminoacid supplement versus very low restricted-calorie diet for preserving muscle mass during weight loss: A pilot double-blind study. European Review for Medical and Pharmacological Sciences 20 (12):2613–21.
  • Molina-Leyva, A., C. Cuenca-Barrales, J. J. Vega-Castillo, J. C. Ruiz-Carrascosa, and R. Ruiz-Villaverde. 2019. Adherence to mediterranean diet in Spanish patients with psoriasis: Cardiovascular benefits? Dermatologic Therapy 32 (2):e12810. doi: 10.1111/dth.12810.
  • Moreno, B., A. B. Crujeiras, D. Bellido, I. Sajoux, and F. F. Casanueva. 2016. Obesity treatment by very low-calorie-ketogenic diet at two years: Reduction in visceral fat and on the burden of disease. Endocrine 54 (3):681–90. doi: 10.1007/s12020-016-1050-2.
  • Moriconi, E., E. Camajani, A. Fabbri, A. Lenzi, and M. Caprio. 2021. Very-low-calorie ketogenic diet as a safe and valuable tool for long-term glycemic management in patients with obesity and type 2 diabetes. Nutrients 13 (3):758. doi: 10.3390/nu13030758.
  • Muscogiuri, G., L. Barrea, D. Laudisio, G. Pugliese, C. Salzano, S. Savastano, and A. Colao. 2019. The management of very low-calorie ketogenic diet in obesity outpatient clinic: A practical guide. Journal of Translational Medicine 17 (1):356. doi: 10.1186/s12967-019-2104-z. PMC: 31665015
  • Muscogiuri, G., M. El Ghoch, A. Colao, M. Hassapidou, V. Yumuk, and L. Busetto, Obesity Management Task Force (OMTF) of the European Association for the Study of Obesity (EASO) 2021. European guidelines for obesity management in adults with a very low-calorie ketogenic diet: A systematic review and meta-analysis. Obesity Facts 14 (2):222–45. doi: 10.1159/000515381.
  • Muzumdar, S., and M. J. Rothe. 2021. Nutrition and psoriasis. Clinics in Dermatology. S0738-081X(21)00217-0. doi: 10.1016/j.clindermatol.2021.10.005.
  • Nutrition, Inflammation and Liver-Spleen Axis 2017. Critical Reviews in Food Science and Nutrition. doi: 10.1080/10408398.2017.1353479.
  • Oku, A., K. Nakai, and D. Tsuruta. 2021. A case of prurigo pigmentosa occurring in a patient with psoriasis vulgaris following a ketogenic diet during the COVID-19 pandemic. International Journal of Dermatology 60 (11):1437–8. doi: 10.1111/ijd.15833.
  • Ou, Z., L. Deng, Z. Lu, F. Wu, W. Liu, D. Huang, and Y. Peng. 2020. Protective effects of Akkermansia muciniphila on cognitive deficits and amyloid pathology in a mouse model of Alzheimer’s disease. Nutrition and Diabetes. 10 (1):12–22. doi: 10.1038/s41387-020-0115-8. PMC: 32321934
  • Owczarczyk-Saczonek, A., and W. Placek. 2017. Compounds of psoriasis with obesity and overweight. Postępy Higieny i Medycyny Doświadczalnej 71 (1). doi: 10.5604/01.3001.0010.3854.
  • Paroutoglou, K., E. Papadavid, G. S. Christodoulatos, and M. Dalamaga. 2020. Deciphering the association between psoriasis and obesity: Current evidence and treatment considerations. Current Obesity Reports 9 (3):165–78. doi: 10.1007/s13679-020-00380-3.
  • Phan, C., M. Touvier, E. Kesse-Guyot, M. Adjibade, S. Hercberg, P. Wolkenstein, O. Chosidow, K. Ezzedine, and E. Sbidian. 2018. Association between mediterranean anti-inflammatory dietary profile and severity of psoriasis: Results from the NutriNet-Santé cohort. JAMA Dermatology 154 (9):1017. doi: 10.1001/jamadermatol.2018.2127.
  • Pona, A., W. Haidari, S. S. Kolli, and S. R. Feldman. 2019. Diet and psoriasis. Dermatology Online Journal 25 (2):1–26. doi: 10.5070/D3252042883.
  • Ramsay, B., and M. Y. R. A. O’Reagan. 1988. A survey of the social and psychological effects of psoriasis. British Journal of Dermatology 118 (2):195–201. doi: 10.1111/j.1365-2133.1988.tb01774.x.
  • Rendon, A., and K. Schäkel. 2019. Psoriasis pathogenesis and treatment. International Journal of Molecular Sciences 20 (6):1475. doi: 10.3390/ijms20061475.
  • Rinninella, E., P. Raoul, M. Cintoni, F. Franceschi, G. A. D. Miggiano, A. Gasbarrini, and M. C. Mele. 2019. What is the healthy gut microbiota composition? A changing ecosystem across age, environment, diet, and diseases. Microorganisms 7 (1):14. doi: 10.3390/microorganisms7010014.
  • Rondanelli, M., C. Gasparri, G. Peroni, M. A. Faliva, M. Naso, S. Perna, P. Bazire, I. Sajoux, R. Maugeri, and C. Rigon. 2021. The potential roles of very low calorie, very low calorie ketogenic diets and very low carbohydrate diets on the gut microbiota composition. Frontiers in Endocrinology 12:662591. doi: 10.3389/fendo.2021.662591.
  • Ruggeri, R. M., S. Giovinazzo, M. C. Barbalace, M. Cristani, A. Alibrandi, T. M. Vicchio, G. Giuffrida, M. H. Aguennouz, M. Malaguti, C. Angeloni, et al. 2021. Influence of Dietary Habits on Oxidative Stress Markers in Hashimoto’s Thyroiditis. Thyroid 31 (1):96–105. doi: 10.1089/thy.2020.0299.
  • Saad, M. J. A., A. Santos, and P. O. Prada. 2016. Linking gut microbiota and inflammation to obesity and insulin resistance. Physiology 31 (4):283–93. doi: 10.1152/physiol.00041.2015.
  • Santangelo, C., R. Vari, B. Scazzocchio, P. De Sanctis, C. Giovannini, M. D’Archivio, and R. Masella. 2018. Anti-inflammatory activity of extra virgin olive oil polyphenols: Which role in the prevention and treatment of immune-mediated inflammatory diseases? Endocrine, Metabolic & Immune Disorders Drug Targets 18 (1):36–50. doi: 10.2174/1871530317666171114114321.
  • Scheffer, D. d L., and A. Latini. 2020. Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs. Biochimica et Biophysica Acta - Molecular Basis of Disease 1866 (10):165823. doi: 10.1016/j.bbadis.2020.165823.
  • Schwarz, P. E. H., A. Pinter, N. Melzer, P. Barteczek, and M. Reinhardt. 2019. ERAPSO: Revealing the High Burden of Obesity in German Psoriasis Patients. Dermatology and Therapy 9 (3):579–87. doi: 10.1007/s13555-019-0314-1.
  • Shapiro, J., N. A. Cohen, V. Shalev, A. Uzan, O. Koren, and N. Maharshak. 2019. Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls. The Journal of Dermatology 46 (7):595–603. doi: 10.1111/1346-8138.14933.
  • Stegenga, H., A. Haines, K. Jones, and J. Wilding, Guideline Development Group 2014. Identification, assessment, and management of overweight and obesity: Summary of updated NICE guidance. BMJ (Clinical Research ed.) 349:g6608. doi: 10.1136/bmj.g6608.
  • Stewart, W. A., K. Gordon, and P. Camfield. 2001. Acute pancreatitis causing death in a child on the ketogenic diet. Journal of Child Neurology 16 (9):682– . doi: 10.1177/088307380101600910.
  • Tan, L., S. Zhao, W. Zhu, L. Wu, J. Li, M. Shen, L. Lei, X. Chen, and C. Peng. 2018. The Akkermansia muciniphila is a gut microbiota signature in psoriasis. Experimental Dermatology 27 (2):144–9. doi: 10.1111/exd.13463.
  • Todberg, T., H. Kaiser, C. Zachariae, A. Egeberg, A.-S. Halling, and L. Skov. 2021. Characterization of the oral and gut microbiota in patients with psoriatic diseases: A systematic review. Acta Dermato-venereologica 101 (7):adv00512. adv00512doi: 10.2340/00015555-3882.
  • Toskes, P. P. 1990. Hyperlipidemic pancreatitis. Gastroenterology Clinics of North America 19 (4):783–91. http://www.ncbi.nlm.nih.gov/pubmed/2269517. doi: 10.1016/S0889-8553(21)00513-6.
  • Tremaroli, V., and F. Bäckhed. 2012. Functional interactions between the gut microbiota and host metabolism. Nature 489 (7415):242–9. doi: 10.1038/nature11552.
  • Wang, J., X. Gu, J. Yang, Y. Wei, and Y. Zhao. 2019. Gut Microbiota dysbiosis and increased plasma LPS and TMAO levels in patients with preeclampsia. Frontiers in Cellular and Infection Microbiology 9:409. doi: 10.3389/fcimb.2019.00409.
  • Wang, Z., and Y. Zhao. 2018. Gut microbiota derived metabolites in cardiovascular health and disease. Protein & Cell 9 (5):416–31. doi: 10.1007/s13238-018-0549-0.
  • Warburton, D. E. R., and S. S. D. Bredin. 2017. Health benefits of physical activity: A systematic review of current systematic reviews. Current Opinion in Cardiology 32 (5):541–56. doi: 10.1097/HCO.0000000000000437.
  • Wiciński, M., D. Adamkiewicz, M. Adamkiewicz, M. Śniegocki, M. Podhorecka, P. Szychta, and B. Malinowski. 2019. Impact of vitamin D on physical efficiency and exercise performance—a review. Nutrients 11 (11):2826. doi: 10.3390/nu11112826.
  • Wilson, J. M., R. P. Lowery, M. D. Roberts, M. H. Sharp, J. M. Joy, K. A. Shields, J. M. Partl, J. S. Volek, and D. P. D’Agostino. 2020. Effects of ketogenic dieting on body composition, strength, power, and hormonal profiles in resistance training men. Journal of Strength and Conditioning Research 34 (12):3463–74. doi: 10.1519/JSC.0000000000001935.
  • Wilson, P. B., K. A. Bohjanen, S. J. Ingraham, and A. S. Leon. 2012. Psoriasis and physical activity: A review. Journal of the European Academy of Dermatology and Venereology 26 (11):1345–53. doi: 10.1111/j.1468-3083.2012.04494.x.
  • Wilson, P. B. 2016. Cardiorespiratory fitness among individuals with psoriasis in the general population. Journal of Physical Activity and Health 13 (7):771–5. doi: 10.1123/jpah.2015-0150.
  • Wilson, P. B. 2017. Prevalence of weight loss attempts and behaviors used by individuals with psoriasis in the United States population. Journal of Dermatological Treatment 28 (6):515–9. doi: 10.1080/09546634.2016.1277180.
  • Wu, A. G., and J. M. Weinberg. 2019a. Correction: The impact of diet on psoriasis. Cutis 104 (4):241.
  • Wu, A. G, and J. M. Weinberg. 2019b. The impact of diet on psoriasis. Cutis. 104 (2S):7–10.
  • Xu, Y., N. Wang, H.-Y. Tan, S. Li, C. Zhang, and Y. Feng. 2020. Function of Akkermansia muciniphila in obesity: Interactions with lipid metabolism, immune response and gut systems. Frontiers in Microbiology 11:219. doi: 10.3389/fmicb.2020.00219.
  • Yasuda, H., H. Kobayashi, and A. Ohkawara. 1990. A survey of the social and psychological effects of psoriasis. Nippon Hifuka Gakkai Zasshi. The Japanese Journal of Dermatology. 100 (11):1167–71.doi: 10.14924/dermatol.100.1167.
  • Zhang, T. Q. Li, L. Cheng, H. Buch, and F. Zhang. 2019. Akkermansia muciniphila is a promising probiotic. Microbial Biotechnology. 12 (6):1109–1125. doi: 10.1111/1751-7915.13410.

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