Toward the bioactive potential of myricitrin in food production: state-of-the-art green extraction and trends in biosynthesis

References

• Agullo, G., L. Gamet-Payrastre, S. Manenti, C. Viala, C. Rémésy, H. Chap, and B. Payrastre. 1997. Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition. Biochemical Pharmacology 53 (11):1649–57. doi: 10.1016/s0006-2952(97)82453-7.
   PubMed Web of Science ®Google Scholar
• Ahangarpour, A., A. A. Oroojan, L. Khorsandi, M. Kouchak, and M. Badavi. 2018a. Antioxidant effect of myricitrin on hyperglycemia-induced oxidative stress in C2C12 cell. Cell Stress & Chaperones 23 (4):773–81. doi: 10.1007/s12192-018-0888-z.
   PubMed Web of Science ®Google Scholar
• Ahangarpour, A., A. A. Oroojan, L. Khorsandi, M. Kouchak, and M. Badavi. 2018b. Solid lipid nanoparticles of myricitrin have antioxidant and antidiabetic effects on streptozotocin-nicotinamide-induced diabetic model and myotube cell of male mouse. Oxidative Medicine and Cellular Longevity 2018:1–18. doi: 10.1155/2018/7496936.
   Web of Science ®Google Scholar
• Ahangarpour, A., A. A. Oroojan, L. Khorsandi, M. Kouchak, and M. Badavi. 2021. Hyperglycemia-induced oxidative stress in isolated proximal tubules of mouse: The in vitro effects of myricitrin and its solid lipid nanoparticle. Archives of Physiology and Biochemistry 127 (5):422–8. doi: 10.1080/13813455.2019.1647250.
   PubMed Web of Science ®Google Scholar
• Aldridge, S. 2012. Toll-like receptor blocker slows beta cell death in type 1 diabetes. Nature Biotechnology 30 (2):124. doi: 10.1038/nbt0212-124c.
   PubMed Web of Science ®Google Scholar
• Ali Redha, A. 2021. Review on extraction of phenolic compounds from natural sources using green deep eutectic solvents. Journal of Agricultural and Food Chemistry 69 (3):878–912. doi: 10.1021/acs.jafc.0c06641.
   PubMed Web of Science ®Google Scholar
• AlYammahi, J., K. Rambabu, A. Thanigaivelan, G. Bharath, S. W. Hasan, P. L. Show, and F. Banat. 2022. Advances of non-conventional green technologies for phyto-saccharides extraction: Current status and future perspectives. Phytochemistry Reviews. doi: 10.1007/s11101-022-09831-2.
   Web of Science ®Google Scholar
• Ameer, K., H. M. Shahbaz, and J.-H. Kwon. 2017. Green extraction methods for polyphenols from plant matrices and their byproducts: A review. Comprehensive Reviews in Food Science and Food Safety 16 (2):295–315. doi: 10.1111/1541-4337.12253.
   PubMed Web of Science ®Google Scholar
• Anana, D. D., S. B. Waller, C. Giordani, S. C. Perera, G. D. Capella, N. Berne, A. L. Strothmann, R. A. Freitag, and M. B. Cleff. 2022. Ovicidal activity of the hydroalcoholic extract of Brazilian peppertree (Schinus terebinthifolia Raddi) against Ancylostoma spp. from naturally parasitized dogs. Natural Product Research 36 (22):5899–903. doi: 10.1080/14786419.2021.2023145.
   PubMed Web of Science ®Google Scholar
• Araujo, N. M. P., H. S. Arruda, F. N. dos Santos, D. R. de Morais, G. A. Pereira, and G. M. Pastore. 2020. LC-MS/MS screening and identification of bioactive compounds in leaves, pulp and seed from Eugenia calycina Cambess. Food Research International 137:109556. doi: 10.1016/j.foodres.2020.109556.
   PubMed Web of Science ®Google Scholar
• Armstrong, C. G., K. J. Kim, L. M. L. Pham, E. Park, Z. Zhong, G. Huang, J. C. Wu, S. P. Elmer, V. Visuthikraisee, E. M. G. Cadag, et al. 2017. Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity. United States Patent No.
   Google Scholar
• Asano, N., T. Kuno, Y. Hirose, Y. Yamada, K. Yoshida, H. Tomita, Y. Nakamura, and H. Mori. 2007. Preventive effects of a flavonoid myricitrin on the formation of azoxymethane-induced premalignant lesions in colons of rats. Asian Pacific Journal of Cancer Prevention 8 (1):73–6.
   PubMedGoogle Scholar
• Azuma, A., H. Yakushiji, Y. Koshita, and S. Kobayashi. 2012. Flavonoid biosynthesis-related genes in grape skin are differentially regulated by temperature and light conditions. Planta 236 (4):1067–80. doi: 10.1007/s00425-012-1650-x.
   PubMed Web of Science ®Google Scholar
• Bao, Y., L. Reddivari, and J.-Y. Huang. 2020. Enhancement of phenolic compounds extraction from grape pomace by high voltage atmospheric cold plasma. LWT 133:109970. doi: 10.1016/j.lwt.2020.109970.
   Web of Science ®Google Scholar
• Barp, L., A. M. Višnjevec, and S. Moret. 2023. Pressurized liquid extraction: A powerful tool to implement extraction and purification of food contaminants. Foods 12 (10):2017. doi: 10.3390/foods12102017.
   PubMed Web of Science ®Google Scholar
• Ben Kaab, S., H. Jijakli, R. Ksouri, O. Parisi, and S. Dal Maso. 2020. Herbicidal composition comprising at least one phenolic active compound. United States Patent No.
   Google Scholar
• Bernstein, H. G., B. Bogerts, and G. Keilhoff. 2005. The many faces of nitric oxide in schizophrenia. A review. Schizophrenia Research 78 (1):69–86. doi: 10.1016/j.schres.2005.05.019.
   PubMed Web of Science ®Google Scholar
• Calassara, L. L., S. C. Pinto, C. P. M. Condack, B. F. Leite, L. Nery, L. W. Tinoco, F. A. Aguiar, I. C. R. Leal, S. M. Martins, L. L. da Silva, et al. 2021. Isolation and characterization of flavonoids from Tapirira guianensis leaves with vasodilatory and myeloperoxidase-inhibitory activities. Natural Product Research 35 (23):5480–3. doi: 10.1080/14786419.2020.1784170.
   PubMed Web of Science ®Google Scholar
• Cannavacciuolo, C., S. Pagliari, J. Frigerio, C. M. Giustra, M. Labra, and L. Campone. 2022. Natural deep eutectic solvents (NADESs) combined with sustainable extraction techniques: A review of the green chemistry approach in food analysis. Foods 12 (1):56. doi: 10.3390/foods12010056.
   PubMed Web of Science ®Google Scholar
• Cao, M. Y., J. Wu, L. Wu, Z. Gu, C. Q. Xie, L. Y. Wu, J. W. Hu, and G. Z. Xu. 2022. Separation of three flavonoid glycosides from Polygonum multiflorum Thunb. leaves using HSCCC and their antioxidant activities. European Food Research and Technology 248 (1):129–39. doi: 10.1007/s00217-021-03865-0.
   Web of Science ®Google Scholar
• Chang, C. H., G. Yu Lin, R. D. Kenneth, and C. Y. Wa. 2005. Myricitrin compounds for sleeping disorders.
   Google Scholar
• Chanioti, S., and C. Tzia. 2018. Extraction of phenolic compounds from olive pomace by using natural deep eutectic solvents and innovative extraction techniques. Innovative Food Science & Emerging Technologies 48:228–39. doi: 10.1016/j.ifset.2018.07.001.
   Web of Science ®Google Scholar
• Chawla, D., S. Bansal, B. D. Banerjee, S. V. Madhu, O. P. Kalra, and A. K. Tripathi. 2014. Role of advanced glycation end product (AGE)-induced receptor (RAGE) expression in diabetic vascular complications. Microvascular Research 95:1–6. doi: 10.1016/j.mvr.2014.06.010.
   PubMed Web of Science ®Google Scholar
• Chemat, F., N. Rombaut, A.-G. Sicaire, A. Meullemiestre, A.-S. Fabiano-Tixier, and M. Abert-Vian. 2017. Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review. Ultrasonics Sonochemistry 34:540–60. doi: 10.1016/j.ultsonch.2016.06.035.
   PubMed Web of Science ®Google Scholar
• Chen, M., P. Sun, A. Date, E. Yuyama, and D. L. Bissett. 2006a. Skin care composition. United States Patent No.
   Google Scholar
• Chen, M., P. Sun, A. Date, E. Yuyama, and D. L. Bissett. 2006b. Substrate based skin care device. United States Patent No.
   Google Scholar
• Chen, Y., X. Qie, W. Quan, M. Zeng, F. Qin, J. Chen, B. Adhikari, and Z. He. 2021. Omnifarious fruit polyphenols: An omnipotent strategy to prevent and intervene diabetes and related complication? Critical Reviews in Food Science and Nutrition :1–37. doi: 10.1080/10408398.2021.2000932.
   Web of Science ®Google Scholar
• Chen, Y. H., and C. Y. Yang. 2020. Ultrasound-assisted extraction of bioactive compounds and antioxidant capacity for thevValorization of Elaeocarpus serratus L. leaves. Processes 8 (10):1218. doi: 10.3390/pr8101218.
   Web of Science ®Google Scholar
• Cheng, M.-H., K. A. Rosentrater, J. Sekhon, T. Wang, S. Jung, and L. A. Johnson. 2019. Economic feasibility of soybean oil production by enzyme-assisted aqueous extraction processing. Food and Bioprocess Technology 12 (3):539–50. doi: 10.1007/s11947-018-2228-9.
   Web of Science ®Google Scholar
• Cho, B. O., J. Y. Shin, J. S. Kim, D. N. Che, H. J. Kang, H. J. Kang, H. Oh, Y. S. Kim, and S. I. Jang. 2020. Enzyme-treated date plum leave extract ameliorates atopic dermatitis-like skin lesion in hairless mice. Asian Pacific Journal of Tropical Biomedicine 10 (6):239–47. doi: 10.4103/2221-1691.283937.
   Web of Science ®Google Scholar
• Clatworthy, A. L., P. A. Illich, G. A. Castro, and E. T. Walters. 1995. Role of peri-axonal inflammation in the development of thermal hyperalgesia and guarding behavior in a rat model of neuropathic pain. Neuroscience Letters 184 (1):5–8. doi: 10.1016/0304-3940(94)11154-b.
   PubMed Web of Science ®Google Scholar
• Dairi, S., K. Madani, M. Aoun, J. L. K. Him, P. Bron, C. Lauret, J.-P. Cristol, and M.-A. Carbonneau. 2014. Antioxidative properties and ability of phenolic compounds of myrtus communis leaves to counteract in vitro LDL and phospholipid aqueous dispersion oxidation. Journal of Food Science 79 (7):C1260–C1270. doi: 10.1111/1750-3841.12517.
   PubMed Web of Science ®Google Scholar
• Daskalaki, A., M. E. Grafakou, C. Barda, Z. Kypriotakis, J. Heilmann, and H. Skaltsa. 2021. Secondary metabolites from Hypericum trichocaulon Boiss. & Heldr., growing wild in the island of crete. Biochemical Systematics and Ecology 97:104294. doi: 10.1016/j.bse.2021.104294.
   Web of Science ®Google Scholar
• de Aguiar, A. C., R. Vardanega, J. Viganó, and E. K. Silva. 2023. Supercritical carbon dioxide technology for recovering valuable phytochemicals from Cannabis sativa L. and valorization of its biomass for food applications. Molecules 28 (9):3849. doi: 10.3390/molecules28093849.
   PubMed Web of Science ®Google Scholar
• Del Rio, D., G. Borges, and A. Crozier. 2010. Berry flavonoids and phenolics: Bioavailability and evidence of protective effects. British Journal of Nutrition 104 (S3):S67–S90. doi: 10.1017/S0007114510003958.
   PubMed Web of Science ®Google Scholar
• Ding, G. L., Y. Liu, M. E. Liu, J. X. Pan, M. X. Guo, J. Z. Sheng, and H. F. Huang. 2015. The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis. Asian Journal of Andrology 17 (6):948–53. doi: 10.4103/1008-682x.150844.
   PubMed Web of Science ®Google Scholar
• Domitrovic, R., K. Rashed, O. Cvijanovic, S. Vladimir-Knezevic, M. Skoda, and A. Visnic. 2015. Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice. Chemico-Biological Interactions 230:21–9. doi: 10.1016/j.cbi.2015.01.030.
   PubMed Web of Science ®Google Scholar
• Donadon, M., A. F. Molinari, F. Corazzi, L. Rocchi, P. Zito, M. Cimino, G. Costa, F. Raimondi, and G. Torzilli. 2016. Pharmacological modulation of ischemic-reperfusion injury during pringle maneuver in hepatic surgery. A prospective randomized pilot study. World Journal of Surgery 40 (9):2202–12. doi: 10.1007/s00268-016-3506-1.
   PubMed Web of Science ®Google Scholar
• Dua, T. K., S. Joardar, P. Chakraborty, S. Bhowmick, A. Saha, V. De Feo, and S. Dewanjee. 2021. Myricitrin, a glycosyloxyflavone in Myrica esculenta bark ameliorates diabetic nephropathy via improving glycemic status, reducing oxidative stress, and suppressing inflammation. Molecules 26 (2):258. doi: 10.3390/molecules26020258.
   PubMed Web of Science ®Google Scholar
• El Achkar, T., H. Greige-Gerges, and S. Fourmentin. 2021. Basics and properties of deep eutectic solvents: A review. Environmental Chemistry Letters 19 (4):3397–408. doi: 10.1007/s10311-021-01225-8.
   Web of Science ®Google Scholar
• Emura, K., H. Oka, and H. Tanaka. 2012. Readily water-soluble myricitrin composition. United States Patent No.
   Google Scholar
• Fakhri, S., S. Z. Moradi, Z. Nouri, H. Cao, H. Wang, H. Khan, and J. Xiao. 2022. Modulation of integrin receptor by polyphenols: Downstream Nrf2-Keap1/ARE and associated cross-talk mediators in cardiovascular diseases. Critical Reviews in Food Science and Nutrition :1–25. doi: 10.1080/10408398.2022.2118226.
   PubMed Web of Science ®Google Scholar
• Farooq, M. O., and R. Bataller. 2016. Pathogenesis and management of alcoholic liver disease. Digestive Diseases (Basel, Switzerland) 34 (4):347–55. doi: 10.1159/000444545.
   PubMed Web of Science ®Google Scholar
• Feng, T., M. Zhang, Q. Sun, A. S. Mujumdar, and D. Yu. 2022. Extraction of functional extracts from berries and their high quality processing: A comprehensive review. Critical Reviews in Food Science and Nutrition :1–18. doi: 10.1080/10408398.2022.2040418.
   Web of Science ®Google Scholar
• Fernandes, A., N. Mateus, and V. de Freitas. 2023. Polyphenol-dietary fiber conjugates from fruits and vegetables: Nature and biological fate in a food and nutrition perspective. Foods 12 (5):1052. doi: 10.3390/foods12051052.
   PubMed Web of Science ®Google Scholar
• Fernandez, S. P., M. Nguyen, T. T. Yow, C. Chu, G. Johnston, J. R. Hanrahan, and M. J. N. R. Chebib. 2009a. The flavonoid glycosides, myricitrin. Gossypin and Naringin Exert Anxiolytic Action in Mice 34 (10):1867–75.
   Google Scholar
• Fernandez, S. P., M. Nguyen, T. T. Yow, C. Chu, G. A. R. Johnston, J. R. Hanrahan, and M. Chebib. 2009b. The flavonoid glycosides, myricitrin, gossypin and naringin exert anxiolytic action in mice. Neurochemical Research 34 (10):1867–75. doi: 10.1007/s11064-009-9969-9.
   PubMed Web of Science ®Google Scholar
• Figueroa-Gonzalez, G., and C. Perez-Plasencia. 2017. Strategies for the evaluation of DNA damage and repair mechanisms in cancer. Oncology Letters 13 (6):3982–8. doi: 10.3892/ol.2017.6002.
   PubMed Web of Science ®Google Scholar
• Fiorentino Gomez, S., M. Cifuentes Barreto, J. F. Hernandez Montaño, S. P. Santander Gonzales, P. C. P. Urueña, and D. M. Castañeda Uvajoa. 2012. Bioactive fraction of Petiveria alliacea, pharmaceutical composition containing same, and combination with immunostimulants for treating cancer. United States Patent No.
   Google Scholar
• Gao, C., Qiu, F. Zhang, and G. Chen. 2018. Myricitrin ameliorates ethanol-induced steatosis in mouse AML12 liver cells by activating AMPK, and reducing oxidative stress and expression of inflammatory cytokines.
   Google Scholar
• Gao, J., S. Chen, Z. K. Qiu, L. P. Fang, L. S. Zhang, C. Guo, T. Chen, and L. X. Qiu. 2018. Myricitrin ameliorates ethanol-induced steatosis in mouse AML12 liver cells by activating AMPK, and reducing oxidative stress and expression of inflammatory cytokines. Molecular Medicine Reports 17 (5):7381–7. doi: 10.3892/mmr.2018.8740.
   PubMed Web of Science ®Google Scholar
• Gao, J., C. C. Liu, H. P. Zhang, Z. Sun, and R. M. Wang. 2019. Myricitrin exhibits anti-atherosclerotic and anti-hyperlipidemic effects in diet-induced hypercholesterolemic rats. AMB Express 9 (1):204. doi: 10.1186/s13568-019-0924-0.
   Web of Science ®Google Scholar
• Gao, Y., B. Ya, X. Li, Y. Guo, H. J. M. Yin, and C. Biochemistry. 2020. Myricitrin ameliorates cognitive deficits in MCAOcerebral strokeratsvia histone acetylation-induced alterations of brain-derived neurotrophic factor. Molecular and Cellular Biochemistry 476:1–9.
   PubMed Web of Science ®Google Scholar
• Gao, Y., B. L. Ya, X. J. Li, Y. Guo, and H. Y. Yin. 2021. Myricitrin ameliorates cognitive deficits in MCAO cerebral stroke rats via histone acetylation-induced alterations of brain-derived neurotrophic factor. Molecular and Cellular Biochemistry 476 (2):609–17. doi: 10.1007/s11010-020-03930-4.
   PubMed Web of Science ®Google Scholar
• Gomes, D., L. R. Rodrigues, and J. L. Rodrigues. 2022. Perspectives on the design of microbial cell factories to produce prenylflavonoids. International Journal of Food Microbiology 367:109588. doi: 10.1016/j.ijfoodmicro.2022.109588.
   PubMed Web of Science ®Google Scholar
• Gomez-Martinez, H., F. Gil-Munoz, A. Bermejo, E. Zuriaga, and M. L. Badenes. 2021. Insights of phenolic pathway in fruits: Transcriptional and metabolic profiling in apricot (Prunus armeniaca). International Journal of Molecular Sciences 22 (7):3411. doi: 10.3390/ijms22073411.
   PubMed Web of Science ®Google Scholar
• Gong, J., S. Luo, S. Zhao, S. Yin, X. Li, and T. Mou. 2019. Myricitrin attenuates memory impairment in a rat model of sepsis-associated encephalopathy via the NLRP3/Bax/Bcl pathway. Folia Neuropathologica 57 (4):327–34. doi: 10.5114/fn.2019.89856.
   PubMed Web of Science ®Google Scholar
• Gullón, B., T. A. Lú-Chau, M. T. Moreira, J. M. Lema, and G. Eibes. 2017. Rutin: A review on extraction, identification and purification methods, biological activities and approaches to enhance its bioavailability. Trends in Food Science & Technology 67:220–35. doi: 10.1016/j.tifs.2017.07.008.
   Web of Science ®Google Scholar
• Hanson, J. E., and C. Antonacci. 2013. Natural sunscreen composition. United States Patent No.
   Google Scholar
• Hanson, J. E., and C. Antonacci. 2015. Natural sunscreen composition. United States Patent No.
   Google Scholar
• Hashemi, B., F. Shiri, F. Švec, and L. Nováková. 2022. Green solvents and approaches recently applied for extraction of natural bioactive compounds. TrAC Trends in Analytical Chemistry 157:116732. doi: 10.1016/j.trac.2022.116732.
   Web of Science ®Google Scholar
• He, N., P. Y. Wang, Y. Y. Niu, J. Q. Chen, C. Q. Li, and W. Y. Kang. 2019. Evaluation antithrombotic activity and action mechanism of myricitrin. Industrial Crops and Products 129:536–41. doi: 10.1016/j.indcrop.2018.12.036.
   Web of Science ®Google Scholar
• Higbee, J., P. Solverson, M. Zhu, and F. Carbonero. 2022. The emerging role of dark berry polyphenols in human health and nutrition. Food Frontiers 3 (1):3–27. doi: 10.1002/fft2.128.
   Google Scholar
• Hikmawanti, N., P. D. Ramadon, I. Jantan, and A. Mun’im. 2021. Natural deep eutectic solvents (NADES): Phytochemical extraction performance enhancer for pharmaceutical and nutraceutical product development. Plants 10 (10):2091. doi: 10.3390/plants10102091.
   Web of Science ®Google Scholar
• Hobbs, C. A., C. Swartz, R. Maronpot, J. Davis, L. Recio, M. Koyanagi, and S. Hayashi. 2015. Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 83:283–92. doi: 10.1016/j.fct.2015.06.016.
   PubMed Web of Science ®Google Scholar
• Hofer, B. 2016. Recent developments in the enzymatic O-glycosylation of flavonoids. Applied Microbiology and Biotechnology 100 (10):4269–81. doi: 10.1007/s00253-016-7465-0.
   PubMed Web of Science ®Google Scholar
• Hollman, P. C. H. 2004. Absorption, bioavailability, and metabolism of flavonoids. Pharmaceutical Biology 42 (sup1):74–83. doi: 10.3109/13880200490893492.
   Google Scholar
• Hong, J. T., H. C. Kim, H. S. Kim, Y. M. Lee, and K. W. Oh. 2005. The role of nitric oxide on glutaminergic modulation of dopaminergic activation. Pharmacological Research 52 (4):298–301. doi: 10.1016/j.phrs.2005.05.002.
   PubMed Web of Science ®Google Scholar
• Hsu, L. W., S. C. Chang, C. H. Shen, Y. X. Liao, and K. S. Chuang. 2006. Flavone derivatives as TNFalpha inhibitors or antagonists. United States Patent No.
   Google Scholar
• Hu, Z. P., G. Zhao, W. Gou, and H. Cheng. 2020. Myricitrin inhibits vascular endothelial growth factor-induced angiogenesis of human umbilical vein endothelial cells and mice. Biomedicine & Pharmacotherapy 130:110726. doi: 10.1016/j.biopha.2020.110726.
   PubMed Web of Science ®Google Scholar
• Huang, J., X. Zhao, and J. Chory. 2019. The arabidopsis transcriptome responds specifically and dynamically to high light stress. Cell Reports 29 (12):4186–99.e3. doi: 10.1016/j.celrep.2019.11.051.
   PubMed Web of Science ®Google Scholar
• Hwang, E. I., M. Kaneko, Y. Ohnishi, and S. Horinouchi. 2003. Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster. Applied and Environmental Microbiology 69 (5):2699–706. doi: 10.1128/aem.69.5.2699-2706.2003.
   PubMed Web of Science ®Google Scholar
• Jakobek, L., and C. Blesso. 2023. Beneficial effects of phenolic compounds: Native phenolic compounds vs metabolites and catabolites. Critical Reviews in Food Science and Nutrition :1–19. doi: 10.1080/10408398.2023.2208218.
   PubMed Web of Science ®Google Scholar
• JECFA. 2014. Evaluation of certain veterinary drug residues in food Seventy-eighth report of the Joint FAO/WHO Expert Committee on Food Additives Introduction. Evaluation of Certain Veterinary Drug Residues in Food 988:1.
   Google Scholar
• Jha, A. K., and N. Sit. 2022. Extraction of bioactive compounds from plant materials using combination of various novel methods: A review. Trends in Food Science & Technology 119:579–91. doi: 10.1016/j.tifs.2021.11.019.
   Web of Science ®Google Scholar
• Ji, Y., B. Li, M. Qiao, J. Li, H. Xu, L. Zhang, and X. Zhang. 2020. Advances on the in vivo and in vitro glycosylations of flavonoids. Applied Microbiology and Biotechnology 104 (15):6587–600. doi: 10.1007/s00253-020-10667-z.
   PubMed Web of Science ®Google Scholar
• Jimenez-Cortegana, C., P. Iglesias, J. Ribalta, T. Vilarino-Garcia, L. Montanez, F. Arrieta, M. Aguilar, S. Duran, J. C. Obaya, A. Becerra, et al. 2021. Nutrients and dietary approaches in patients with type 2 diabetes mellitus and cardiovascular disease: A narrative review. Nutrients 13 (11):4150. doi: 10.3390/nu13114150.
   PubMed Web of Science ®Google Scholar
• Jo, S., S. Kim, D. H. Shin, and M. S. Kim. 2020. Inhibition of African swine fever virus protease by myricetin and myricitrin. Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1):1045–9. doi: 10.1080/14756366.2020.1754813.
   PubMed Web of Science ®Google Scholar
• Keikhaei, F., M. A. Mirshekar, M. R. Shahraki, and A. Dashipour. 2020. Antiepileptogenic effect of myricitrin on spatial memory and learning in a kainate-induced model of temporal lobe epilepsy. Learning and Motivation 69:101610. doi: 10.1016/j.lmot.2019.101610.
   Web of Science ®Google Scholar
• Khan, H., H. Ullah, P. C. Machado Ferreira Castilho, A. S. Gomila, G. D’Onofrio, R. Filosa, F. Wang, S. M. Nabavi, M. Daglia, A. S. Silva, et al. 2020. Targeting NF-kappa B signaling pathway in cancer by dietary polyphenols. Critical Reviews in Food Science and Nutrition 60 (16):2790–800. doi: 10.1080/10408398.2019.1661827.
   PubMed Web of Science ®Google Scholar
• Khanra, R., N. Bhattacharjee, T. K. Dua, A. Nandy, A. Saha, J. Kalita, P. Manna, and S. Dewanjee. 2017. Taraxerol, a pentacyclic triterpenoid, from Abroma augusta leaf attenuates diabetic nephropathy in type 2 diabetic rats. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 94:726–41. doi: 10.1016/j.biopha.2017.07.112.
   PubMed Web of Science ®Google Scholar
• Kim, D. Y., S. R. Kim, and U. J. Jung. 2020. Myricitrin ameliorates hyperglycemia, glucose intolerance, hepatic steatosis, and inflammation in high-fat diet/streptozotocin-induced diabetic mice. International Journal of Molecular Sciences 21 (5):1870.
   PubMed Web of Science ®Google Scholar
• Kim, H. D., K. H. Jeong, U. J. Jung, and S. R. Kim. 2016. Myricitrin ameliorates 6-hydroxydopamine-induced dopaminergic neuronal loss in the substantia nigra of mouse brain. Journal of Medicinal Food 19 (4):374–82. doi: 10.1089/jmf.2015.3581.
   PubMed Web of Science ®Google Scholar
• Kim, H. J., and D. M. Chuang. 2014. HDAC inhibitors mitigate ischemia-induced oligodendrocyte damage: Potential roles of oligodendrogenesis, VEGF, and anti-inflammation. American Journal of Translational Research 6 (3):206–23.
   PubMed Web of Science ®Google Scholar
• Koike, S., N. Shirahata, and K. Okisaka. 2011. Miso. United States Patent No.
   Google Scholar
• Ku, Y. S., M. S. Ng, S. S. Cheng, A. W. Y. Lo, Z. X. Xiao, T. S. Shin, G. Chung, and H. M. Lam. 2020. Understanding the composition, biosynthesis, accumulation and transport of flavonoids in crops for the promotion of crops as healthy sources of flavonoids for human consumption. Nutrients 12 (6):1717. doi: 10.3390/nu12061717.
   PubMed Web of Science ®Google Scholar
• Kumar, S., S. Pipliya, and P. P. Srivastav. 2023. Effect of cold plasma on different polyphenol compounds: A review. Journal of Food Process Engineering 46 (1):14203. doi: 10.1111/jfpe.14203.
   Web of Science ®Google Scholar
• Kurkin, V. A., and N. I. Zimenkina. 2021. HPLC determination of myricitrin in Juglans nigra L. bark. Pharmaceutical Chemistry Journal 55 (9):881–5. doi: 10.1007/s11094-021-02512-y.
   Web of Science ®Google Scholar
• Lebovka, N. I., M. I. Bazhal, and E. Vorobiev. 2002. Estimation of characteristic damage time of food materials in pulsed-electric fields. Journal of Food Engineering 54 (4):337–46. doi: 10.1016/s0260-8774(01)00220-5.
   Web of Science ®Google Scholar
• Lei, Y. 2017. Myricitrin decreases traumatic injury of the spinal cord and exhibits antioxidant and anti-inflammatory activities in a rat model via inhibition of COX-2, TGF-beta 1, p53 and elevation of Bcl-2/Bax signaling pathway. Molecular Medicine Reports 16 (5):7699–705. doi: 10.3892/mmr.2017.7567.
   PubMed Web of Science ®Google Scholar
• Li, H., S. Gao, S. Zhang, W. Zeng, and J. Zhou. 2021. Effects of metabolic pathway gene copy numbers on the biosynthesis of (2S)-naringenin in Saccharomyces cerevisiae. Journal of Biotechnology 325:119–27. doi: 10.1016/j.jbiotec.2020.11.009.
   PubMed Web of Science ®Google Scholar
• Li, H., Y. Lyv, S. Zhou, S. Yu, and J. Zhou. 2022. Microbial cell factories for the production of flavonoids–barriers and opportunities. Bioresource Technology 360:127538. doi: 10.1016/j.biortech.2022.127538.
   PubMed Web of Science ®Google Scholar
• Li, R.,L. Hu,C. Hu,Q. Wang,Y. Lei, andB. Zhao. 2020. Myricitrin protects against cisplatin-induced kidney injury by eliminating excessive reactive oxygen species. International Urology and Nephrology 52 (1):187–196. doi: 10.1007/s11255-019-02334-8. 31828476.
   PubMed Web of Science ®Google Scholar
• Li, R., L. Hu, C. Hu, Q. Wang, B. J. I. U, and Zhao, N. 2020. Myricitrin protects against cisplatin-induced kidney injury by eliminating excessive reactive oxygen species. International Urology and Nephrology 52 (11):1–10.
   PubMedGoogle Scholar
• Lingwan, M., A. A. Pradhan, A. K. Kushwaha, M. A. Dar, L. Bhagavatula, and S. Datta. 2023. Photoprotective role of plant secondary metabolites: Biosynthesis, photoregulation, and prospects of metabolic engineering for enhanced protection under excessive light. Environmental and Experimental Botany 209:105300. doi: 10.1016/j.envexpbot.2023.105300.
   Web of Science ®Google Scholar
• Little, C. H., E. Combet, D. C. McMillan, P. G. Horgan, and C. S. D. Roxburgh. 2017. The role of dietary polyphenols in the moderation of the inflammatory response in early stage colorectal cancer. Critical Reviews in Food Science and Nutrition 57 (11):2310–20. doi: 10.1080/10408398.2014.997866.
   PubMed Web of Science ®Google Scholar
• Liu, S., X. Li, R. Cai, B. Chen, J. Zeng, C. Li, X. Zhou, and Y. Li. 2023. Ultra-high-performance liquid chromatography-quadrupole-exactive-orbitrap-tandem mass spectrometry-based putative identification for Eucommiae folium (Duzhongye) and its quality-marker candidate for pharmacopeia. Journal of Separation Science :2300041. doi: 10.1002/jssc.202300041.
   Web of Science ®Google Scholar
• Liu, T., X. Sui, L. Li, J. Zhang, X. Liang, W. Li, H. Zhang, and S. Fu. 2016. Application of ionic liquids based enzyme-assisted extraction of chlorogenic acid from Eucommia ulmoides leaves. Analytica Chimica Acta 903:91–9. doi: 10.1016/j.aca.2015.11.029.
   PubMed Web of Science ®Google Scholar
• Liu, X., L. Yin, S. Shen, and Y. Hou. 2023. Inflammation and cancer: Paradoxical roles in tumorigenesis and implications in immunotherapies. Genes & Diseases 10 (1):151–64. doi: 10.1016/j.gendis.2021.09.0062352-3042.
   PubMed Web of Science ®Google Scholar
• Liu, X. Y., H. N. Yu, S. Gao, Y. F. Wu, A. X. Cheng, and H. X. Lou. 2017. The isolation and functional characterization of three liverwort genes encoding cinnamate 4-hydroxylase. Plant Physiology and Biochemistry: PPB 117:42–50. doi: 10.1016/j.plaphy.2017.05.016.
   PubMed Web of Science ®Google Scholar
• Long, J., P. Guan, X. Hu, L. Y. Yang, L. Q. He, Q. L. Lin, F. J. Luo, J. Z. Li, X. G. He, Z. L. Du, et al. 2021. Natural polyphenols as targeted modulators in colon cancer: Molecular mechanisms and applications. Frontiers in Immunology 12:635484. doi: 10.3389/fimmu.2021.635484.
   PubMed Web of Science ®Google Scholar
• Lopez-Lazaro, M., E. Willmore, and C. A. Austin. 2010. The dietary flavonoids myricetin and fisetin act as dual inhibitors of DNA topoisomerases I and II in cells. Mutation Research 696 (1):41–7. doi: 10.1016/j.mrgentox.2009.12.010.
   PubMed Web of Science ®Google Scholar
• Lou, J., H. Duan, Q. Qin, Z. Teng, F. Gan, X. Zhou, and X. Zhou. 2023. Advances in Oral drug delivery systems: Challenges and opportunities. Pharmaceutics 15 (2):484. doi: 10.3390/pharmaceutics15020484.
   PubMed Web of Science ®Google Scholar
• Louvet, A., and P. Mathurin. 2015. Alcoholic liver disease: Mechanisms of injury and targeted treatment. Nature Reviews. Gastroenterology & Hepatology 12 (4):231–42. doi: 10.1038/nrgastro.2015.35.
   PubMed Web of Science ®Google Scholar
• Lu, Y., E. Zhang, J. Yang, and Z. Cao. 2018. Strategies to improve micelle stability for drug delivery. Nano Research 11 (10):4985–98. doi: 10.1007/s12274-018-2152-3.
   PubMed Web of Science ®Google Scholar
• Luo, X. D., M. J. Basile, and E. J. Kennelly. 2002. Polyphenolic antioxidants from the fruits of Chrysophyllum cainito L. (star apple). Journal of Agricultural and Food Chemistry 50 (6):1379–82. doi: 10.1021/jf011178n.
   PubMed Web of Science ®Google Scholar
• Lv, H. M., B. Y. An, Q. L. Yu, Y. Cao, Y. Liu, and S. Z. Li. 2020. The hepatoprotective effect of myricetin against lipopolysaccharide and D-galactosamine-induced fulminant hepatitis. International Journal of Biological Macromolecules 155:1092–104. doi: 10.1016/j.ijbiomac.2019.11.075.
   PubMed Web of Science ®Google Scholar
• Ma, J., X. D. Luo, P. Protiva, H. Yang, C. Y. Ma, M. J. Basile, I. B. Weinstein, and E. J. Kennelly. 2003. Bioactive novel polyphenols from the fruit of Manilkara zapota (Sapodilla). Journal of Natural Products 66 (7):983–6. doi: 10.1021/np020576x.
   PubMed Web of Science ®Google Scholar
• Ma, R., R. Zhou, R. Tong, S. Shi, and X. Chen. 2017. At-line hyphenation of high-speed countercurrent chromatography with Sephadex LH-20 column chromatography for bioassay-guided separation of antioxidants from vine tea (Ampelopsis grossedentata). Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 1040:112–7. doi: 10.1016/j.jchromb.2016.11.037.
   PubMed Web of Science ®Google Scholar
• Mangmool, S., I. Kunpukpong, W. Kitphati, and N. Anantachoke. 2021. Antioxidant and anticholinesterase activities of extracts and phytochemicals of Syzygium antisepticum leaves. Molecules 26 (11):3295. doi: 10.3390/molecules26113295.
   PubMed Web of Science ®Google Scholar
• Maronpot, R. R., M. Koyanagi, J. Davis, L. Recio, D. Marbury, M. Boyle, and S. M. Hayashi. 2015. Safety assessment and single-dose toxicokinetics of the flavouring agent myricitrin in Sprague-Dawley rats. Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment 32 (11):1799–809. doi: 10.1080/19440049.2015.1084653.
   PubMed Web of Science ®Google Scholar
• Meeran, S. M., and S. K. Katiyar. 2008. Cell cycle control as a basis for cancer chemoprevention through dietary agents. Frontiers in Bioscience: A Journal and Virtual Library 13:2191–202. doi: 10.2741/2834.
   PubMed Web of Science ®Google Scholar
• Mehta, N., J. S, P. Kumar, A. K. Verma, P. Umaraw, S. K. Khatkar, A. B. Khatkar, D. Pathak, U. Kaka, and A. Q. Sazili. 2022. Ultrasound-assisted extraction and the encapsulation of bioactive components for food applications. Foods 11 (19):2973. doi: 10.3390/foods11192973.
   PubMed Web of Science ®Google Scholar
• Meotti, F. C., R. Fachinetto, L. C. Maffi, F. C. Missau, M. G. Pizzolatti, J. B. Rocha, and A. R. Santos. 2007. Antinociceptive action of myricitrin: Involvement of the K+ and Ca2+ channels. European Journal of Pharmacology 567 (3):198–205. doi: 10.1016/j.ejphar.2007.03.039.
   PubMed Web of Science ®Google Scholar
• Meotti, F. C., A. P. Luiz, M. G. Pizzolatti, C. A. Kassuya, J. B. Calixto, and A. R. Santos. 2006. Analysis of the antinociceptive effect of the flavonoid myricitrin: Evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways. The Journal of Pharmacology and Experimental Therapeutics 316 (2):789–96. doi: 10.1124/jpet.105.092825.
   PubMed Web of Science ®Google Scholar
• Meotti, F. C., F. C. Missau, J. Ferreira, M. G. Pizzolatti, C. Mizuzaki, C. W. Nogueira, and A. R. S. Santos. 2006. Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice. Biochemical Pharmacology 72 (12):1707–13. doi: 10.1016/j.bcp.2006.08.028.
   PubMed Web of Science ®Google Scholar
• Meotti, F. C., T. Posser, F. C. Missau, M. G. Pizzolatti, R. B. Leal, and A. R. S. Santos. 2007. Involvement of p38(MAPK) on the antinociceptive action of myricitrin in mice. Biochemical Pharmacology 74 (6):924–31. doi: 10.1016/j.bcp.2007.06.024.
   PubMed Web of Science ®Google Scholar
• Meyer, E., M. A. Mori, A. C. Campos, R. Andreatini, F. S. Guimaraes, H. Milani, and R. M. W. de Oliveira. 2017. Myricitrin induces antidepressant-like effects and facilitates adult neurogenesis in mice. Behavioural Brain Research 316:59–65. doi: 10.1016/j.bbr.2016.08.048.
   PubMed Web of Science ®Google Scholar
• Michel, M. C. P., A. G. Guimarães, C. A. Paula, S. A. Rezende, M. E. G. Sobral, and D. A. Saúde Guimarães. 2013. Extracts from the leaves of Campomanesia velutina inhibits production of LPS/INF-γ induced inflammatory mediators in J774A.1 cells and exerts anti-inflammatory and antinociceptive effects in vivo. Revista Brasileira de Farmacognosia 23 (6):927–36. doi: 10.1590/S0102-695X2013000600010.
   Google Scholar
• Min, W., S. Gui-Bo, D. Yu-Yang, T. Yu, L. Ping, L. Xue-Song, Y. Jing-Xue, and S. J. F. i P. Xiao-Bo. 2017. Myricitrin protects cardiomyocytes from hypoxia/reoxygenation injury: Involvement of heat shock protein. Frontiers in Pharmacology 8:353.
   PubMed Web of Science ®Google Scholar
• Motlhatlego, K. E., M. A. Abdalla, C. M. Leonard, J. N. Eloff, and L. J. McGaw. 2020. Inhibitory effect of Newtonia extracts and myricetin-3-o-rhamnoside (myricitrin) on bacterial biofilm formation. BMC Complementary Medicine and Therapies 20 (1):358. doi: 10.1186/s12906-020-03139-4.
   PubMedGoogle Scholar
• Motlhatlego, K. E., P. Mehrbod, F. Fotouhi, M. A. Abdalla, J. N. Eloff, and L. J. McGaw. 2021. Anti-influenza A virus activity of two Newtonia species and the isolated compound myricetin-3-o-rhamnoside. BMC Complementary Medicine and Therapies 21 (1):92. doi: 10.1186/s12906-021-03250-0.
   PubMedGoogle Scholar
• Mustafa, A., and C. Turner. 2011. Pressurized liquid extraction as a green approach in food and herbal plants extraction: A review. Analytica Chimica Acta 703 (1):8–18. doi: 10.1016/j.aca.2011.07.018.
   PubMed Web of Science ®Google Scholar
• Na, M. K., J-k Yoo, C. B. Lee, J. P. Kim, G. H. Lim, D. I. Min, and Y. M. Jeon. 2010. Extract of Cercis chinensis having anti-oxidant activity and anti-aging activity, and cosmetical composition containing the extract for anti-oxidation, skin-aging protection and wrinkle improvement. United States Patent No.
   Google Scholar
• Neves, N. C. V., M. P. de Mello, I. Zaidan, L. P. Sousa, A. V. Braga, R. R. Machado, W. Kukula-Koch, F. Boylan, M. V. Caliari, and R. O. Castilho. 2023. Campomanesia lineatifolia Ruiz & Pavón (Myrtaceae): Isolation of major and minor compounds of phenolic-rich extract by high-speed countercurrent chromatography and anti-inflammatory evaluation. Journal of Ethnopharmacology 310:116417. doi: 10.1016/j.jep.2023.116417.
   PubMed Web of Science ®Google Scholar
• Nieto, J. A., S. Santoyo, M. Prodanov, G. Reglero, and L. Jaime. 2020. Valorisation of grape stems as a source of phenolic antioxidants by using a sustainable extraction methodology. Foods 9 (5):604. doi: 10.3390/foods9050604.
   PubMed Web of Science ®Google Scholar
• Nugroho, A., H. Heryani, and W. T. Istikowati. 2019. Quantitative determination of quercitrin and myricitrin in three different parts of Euphorbia hirta as bioflavonoid source for functional food. Paper presented at the 1st International Conference on Food and Bio-Industry (ICFB), Univ Padjadjaran, Bandung, Indonesia.
   Google Scholar
• Ogundele, A. V., A. Yadav, and A. M. Das. 2021. Antimicrobial and alpha-amylase inhibitory activities of constituents from Elaeocarpus floribundus. Revista Brasileira de Farmacognosia 31 (3):330–4. doi: 10.1007/s43450-021-00152-7.
   Google Scholar
• Oliveira, E. S. C., F. L. D. Pontes, L. D. R. Acho, A. S. do Rosario, B. J. P. da Silva, J. D. Bezerra, F. R. Campos, E. S. Lima, and M. B. Machado. 2021. qNMR quantification of phenolic compounds in dry extract of Myrcia multiflora leaves and its antioxidant, anti-AGE, and enzymatic inhibition activities. Journal of Pharmaceutical and Biomedical Analysis 201:114109. doi: 10.1016/j.jpba.2021.114109.
   PubMed Web of Science ®Google Scholar
• Oroojan, A. A., A. Ahangarpour, B. Paknejad, P. Zareian, Z. Hami, and S. R. Abtahi. 2021. Effects of myricitrin and solid lipid nanoparticle-containing myricitrin on reproductive system disorders induced by diabetes in male mouse. The World Journal of Men’s Health 39 (1):147–57. doi: 10.5534/wjmh.190010.
   PubMedGoogle Scholar
• Park, J., B. Lee, H. Choi, W. Kim, H. J. Kim, and H. Cheong. 2016. Antithrombosis activity of protocatechuic and shikimic acids from functional plant Pinus densiflora Sieb. et Zucc needles. Journal of Natural Medicines 70 (3):492–501. doi: 10.1007/s11418-015-0956-y.
   PubMed Web of Science ®Google Scholar
• Parvaneh, T., B. Abedi, G. H. Davarynejad, and E. G. Moghadam. 2019. Enzyme activity, phenolic and flavonoid compounds in leaves of Iranian red flesh apple cultivars grown on different rootstocks. Scientia Horticulturae 246:862–70. doi: 10.1016/j.scienta.2018.11.034.
   Web of Science ®Google Scholar
• Peixoto Araujo, N. M., E. K. Silva, H. S. Arruda, D. Rodrigues de Morais, M. Angela A. Meireles, G. A. Pereira, and G. M. Pastore. 2021. Recovering phenolic compounds from Eugenia calycina Cambess employing high-intensity ultrasound treatments: A comparison among its leaves, fruit pulp, and seed as promising sources of bioactive compounds. Separation and Purification Technology 272:118920. doi: 10.1016/j.seppur.2021.118920.
   Web of Science ®Google Scholar
• Perdomo, R. T., C. P. Defende, P. D. Mirowski, T. V. Freire, S. S. Weber, W. S. Garcez, Z. D. Guterres, M. D. C. Matos, and F. R. Garcez. 2021. Myricitrin from Combretum lanceolatum exhibits inhibitory effect on DNA-topoisomerase type II alpha and protective effect against in Vvvo doxorubicin-induced mutagenicity. Journal of Medicinal Food 24 (3):273–81. doi: 10.1089/jmf.2020.0033.
   PubMed Web of Science ®Google Scholar
• Pereira, M., I. P. Siba, L. R. Chioca, D. Correia, M. Vital, M. G. Pizzolatti, A. R. S. Santos, and R. Andreatini. 2011. Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models. Progress in Neuro-Psychopharmacology & Biological Psychiatry 35 (7):1636–44. doi: 10.1016/j.pnpbp.2011.06.002.
   PubMed Web of Science ®Google Scholar
• Perez-Vazquez, A., M. Carpena, P. Barciela, L. Cassani, J. Simal-Gandara, and M. A. Prieto. 2023. Pressurized liquid extraction for the recovery of bioactive compounds from seaweeds for food industry application: A review. Antioxidants 12 (3):612. doi: 10.3390/antiox12030612.
   Web of Science ®Google Scholar
• Perra, M., F.-J. Leyva-Jiménez, M. L. Manca, M. Manconi, H. N. Rajha, I. Borrás-Linares, A. Segura-Carretero, and J. Lozano-Sánchez. 2023. Application of pressurized liquid extraction to grape by-products as a circular economy model to provide phenolic compounds enriched ingredient. Journal of Cleaner Production 402:136712. doi: 10.1016/j.jclepro.2023.136712.
   Web of Science ®Google Scholar
• Picot-Allain, C., M. F. Mahomoodally, G. Ak, and G. Zengin. 2021. Conventional versus green extraction techniques—A comparative perspective. Current Opinion in Food Science 40:144–56. doi: 10.1016/j.cofs.2021.02.009.
   Web of Science ®Google Scholar
• Prasniewski, A., C. da Silva, B. R. B. Ayres, E. A. da Silva, E. J. Pilau, B. D. Nani, P. L. Rosalen, and T. L. C. Oldoni. 2021. Characterization of phenolic compounds by UHPLC-QTOF-MS/MS and functional properties of Syzygium malaccense leaves. South African Journal of Botany 139:418–26. doi: 10.1016/j.sajb.2021.01.036.
   Web of Science ®Google Scholar
• Pretlow, T. P., C. Cheyer, and M. A. O’Riordan. 1994. Aberrant crypt foci and colon tumors in f344 rats have similar increases in proliferative activity. International Journal of Cancer 56 (4):599–602. doi: 10.1002/ijc.2910560422.
   PubMed Web of Science ®Google Scholar
• Pretlow, T. P., M. Ann O’Riordan, T. G. Pretlow, and T. A. Stellato. 1992. Aberrant crypts in human colonic mucosa – Putative preneoplastic lesions. Journal of Cellular Biochemistry 50 (S16G):55–62. doi: 10.1002/jcb.240501111.
   Google Scholar
• Qi, S., Z. Feng, Q. Li, Z. Qi, and Y. Zhang. 2017. Myricitrin modulates NADPH oxidase-dependent ROS production to inhibit endotoxin-mediated inflammation by blocking the JAK/STAT1 and NOX2/p47(phox) pathways. Oxidative Medicine and Cellular Longevity 2017:1–20. doi: 10.1155/2017/9738745.
   Web of Science ®Google Scholar
• Qian, M., H. Wu, C. Yang, W. Zhu, B. Shi, B. Zheng, S. Wang, K. Zhou, and A. Gao. 2023. RNA-Seq reveals the key pathways and genes involved in the light-regulated flavonoids biosynthesis in mango (Mangifera indica L.) peel. Frontiers in Plant Science 13:1119384. doi: 10.3389/fpls.2022.1119384.
   PubMed Web of Science ®Google Scholar
• Qin, M., Y. Luo, X. B. Meng, M. Wang, H. W. Wang, S. Y. Song, J. X. Ye, R. L. Pan, F. Yao, P. Wu, et al. 2015. Myricitrin attenuates endothelial cell apoptosis to prevent atherosclerosis: An insight into PI3K/Akt activation and STAT3 signaling pathways. Vascular Pharmacology 70:23–34. doi: 10.1016/j.vph.2015.03.002.
   PubMed Web of Science ®Google Scholar
• Ramos Azevedo Oliveira, G., F. dos Santos Grasel, G. P. de Pinho, and F. Oliveira Silvério. 2020. Comparison of chemical composition of lipophilic extracts from Acacia mearnsii De Wild. wood of different ages. Industrial Crops and Products 147:112200. doi: 10.1016/j.indcrop.2020.112200.
   Web of Science ®Google Scholar
• Ren, G., J. Hou, Q. Fang, H. Sun, X. Liu, L. Zhang, and P. G. Wang. 2012. Synthesis of flavonol 3-O-glycoside by UGT78D1. Glycoconjugate Journal 29 (5-6):425–32. doi: 10.1007/s10719-012-9410-5.
   PubMed Web of Science ®Google Scholar
• Rodriguez, A., T. Strucko, S. G. Stahlhut, M. Kristensen, D. K. Svenssen, J. Forster, J. Nielsen, and I. Borodina. 2017. Metabolic engineering of yeast for fermentative production of flavonoids. Bioresource Technology 245 (Pt B):1645–54. doi: 10.1016/j.biortech.2017.06.043.
   PubMed Web of Science ®Google Scholar
• Roy, G., D. Gawkowski, F. Talebi, K. A. Boles, and D. Brand-Levine. 2013. Fading protection of colors derived from natural sources used in beverage products. United States Patent No.
   Google Scholar
• Rukavina, I., M. J. Rodrigues, C. G. Pereira, I. Mansinhos, A. Romano, S. Ślusarczyk, A. Matkowski, and L. Custódio. 2021. Greener Is better: First approach for the use of natural deep eutectic solvents (NADES) to extract antioxidants from the medicinal halophyte Polygonum maritimum L. Molecules 26 (20):6136. doi: 10.3390/molecules26206136.
   PubMed Web of Science ®Google Scholar
• Sanchez-Vega, R., P. Elez-Martinez, and O. Martin-Belloso. 2015. Influence of high-intensity pulsed electric field processing parameters on antioxidant compounds of broccoli juice. Innovative Food Science & Emerging Technologies 29:70–7. doi: 10.1016/j.ifset.2014.12.002.
   Web of Science ®Google Scholar
• Sangeetha, R., T. Pratheeba, C. Ragavendran, and D. Natarajan. 2019. Pouteria campechiana leaf extract and its bioactive compound myricitrin are mosquitocidal against Aedes aegypti and Culex quinquefasciatus. Asian Pacific Journal of Tropical Medicine 12 (7):321. doi: 10.4103/1995-7645.262076.
   Web of Science ®Google Scholar
• Sarkar, M. K., A. Kar, A. Jayaraman, K. Shanmugam, V. Vadivel, and S. K. Mahapatra. 2021. Apoptotic mechanisms of myricitrin isolated from Madhuca longifolia leaves in HL-60 leukemia cells. Molecular Biology Reports 48 (6):5327–34. doi: 10.1007/s11033-021-06500-z.
   PubMed Web of Science ®Google Scholar
• Sarkar, M. K., S. K. Mahapatra, and V. Vadivel. 2020. Oxidative stress mediated cytotoxicity in leukemia cells induced by active phyto-constituents isolated from traditional herbal drugs of West Bengal. Journal of Ethnopharmacology 251:112527. doi: 10.1016/j.jep.2019.112527.
   PubMed Web of Science ®Google Scholar
• Saxena, S., L. Pal, J. Naik, Y. Singh, P. K. Verma, D. Chattopadhyay, and A. Pandey. 2023. The R2R3-MYB-SG7 transcription factor CaMYB39 orchestrates surface phenylpropanoid metabolism and pathogen resistance in chickpea. New Phytologist 238 (2):798–816. doi: 10.1111/nph.18758.
   PubMedGoogle Scholar
• Schaart, J. G., C. Dubos, I. R. De La Fuente, A. van Houwelingen, R. C. H. de Vos, H. H. Jonker, W. J. Xu, J. M. Routaboul, L. Lepiniec, and A. G. Bovy. 2013. Identification and characterization of MYB-bHLH-WD40 regulatory complexes controlling proanthocyanidin biosynthesis in strawberry (Fragaria x ananassa) fruits. The New Phytologist 197 (2):454–67. doi: 10.1111/nph.12017.
   PubMed Web of Science ®Google Scholar
• Sefi, O., S. Bourgou, W. Megdiche-Ksouri, M. Libiad, A. Khabbach, M. El Haissoufi, F. Lamchouri, N. Krigas, and Z. Ghrabi-Gammar. 2022. Daskalaki. International Journal of Environmental Health Research 32 (11):2496–511. doi: 10.1080/09603123.2021.1973970.
   PubMedGoogle Scholar
• Shah, A., and D. L. Smith. 2020. Flavonoids in agriculture: Chemistry and roles in, biotic and abiotic stress responses, and microbial associations. Agronomy 10 (8):1209. doi: 10.3390/agronomy10081209.
   Web of Science ®Google Scholar
• Shen, Y. T., X. R. Shen, Y. Cheng, and Y. L. Liu. 2020. Myricitrin pretreatment ameliorates mouse liver ischemia reperfusion injury. International Immunopharmacology 89:107005. doi: 10.1016/j.intimp.2020.107005.
   PubMed Web of Science ®Google Scholar
• Shimosaki, S., Y. Tsurunaga, H. Itamura, and M. Nakamura. 2011. Anti-allergic effect of the flavonoid myricitrin from Myrica rubra leaf extracts in vitro and in vivo. Natural Product Research 25 (4):374–80. doi: 10.1080/14786411003774320.
   PubMed Web of Science ®Google Scholar
• Si, C., W. Dong, J. A. Teixeira da Silva, C. He, Z. Yu, M. Zhang, L. Huang, C. Zhao, D. Zeng, C. Li, et al. 2023. Functional analysis of flavanone 3-hydroxylase (F3H) from Dendrobium officinale, which confers abiotic stress tolerance. Horticultural Plant Journal 9 (2):356–64. doi: 10.1016/j.hpj.2022.03.006.
   Web of Science ®Google Scholar
• Singh, R. P., and R. Agarwal. 2006. Natural flavonoids targeting deregulated cell cycle progression in cancer cells. Current Drug Targets 7 (3):345–54. doi: 10.2174/138945006776055004.
   PubMed Web of Science ®Google Scholar
• Skarpalezos, D., and A. Detsi. 2019. Deep eutectic solvents as extraction media for valuable flavonoids from natural sources. Applied Sciences 9 (19):4169. doi: 10.3390/app9194169.
   Google Scholar
• Sobolewski, C., N. Legrand, F. Morceau, and M. Diederich. 2010. Inflammation: Novel arrows for an ancient target. Biochemical Pharmacology 80 (12):1769–70. doi: 10.1016/j.bcp.2010.06.026.
   PubMed Web of Science ®Google Scholar
• Soto-Otero, R., E. Mendez-Alvarez, A. Hermida-Ameijeiras, A. M. Lopez-Real, and J. L. Labandeira-Garcia. 2002. Effects of (-)-nicotine and (-)-cotinine on 6-hydroxydopamine-induced oxidative stress and neurotoxicity: Relevance for Parkinson’s disease. Biochemical Pharmacology 64 (1):125–35. doi: 10.1016/s0006-2952(02)01070-5.
   PubMed Web of Science ®Google Scholar
• Storkey, C., D. I. Pattison, J. A. Koehler, D. S. Gaspard, J. C. Evans, E. D. Hagestuen, and M. J. Davies. 2015. Prevention of degradation of the natural high potency sweetener (2R,4R)-monatin in mock beverage solutions. Food Chemistry 173:645–51. doi: 10.1016/j.foodchem.2014.10.054.
   PubMed Web of Science ®Google Scholar
• Sun, H., X. Ge, Y. Lv, and A. Wang. 2012. Application of accelerated solvent extraction in the analysis of organic contaminants, bioactive and nutritional compounds in food and feed. Journal of Chromatography A 1237:1–23. doi: 10.1016/j.chroma.2012.03.003.
   PubMed Web of Science ®Google Scholar
• Sun, J., W. Sun, G. Zhang, B. Lv, and C. Li. 2022. High efficient production of plant flavonoids by microbial cell factories: Challenges and opportunities. Metabolic Engineering 70:143–54. doi: 10.1016/j.ymben.2022.01.011.
   PubMed Web of Science ®Google Scholar
• Sun, T., J. B. Xue, Y. L. Zhou, and X. F. Wang. 2020. Myricitrin regulates proliferation, apoptosis and inflammation of chondrocytes treated with IL-1 beta. Cellular and Molecular Biology 66 (1):65–9. doi: 10.14715/cmb/2019.66.1.11.
   PubMed Web of Science ®Google Scholar
• Syabana, M. A., N. D. Yuliana, I. Batubara, and D. Fardiaz. 2022. Alpha-glucosidase inhibitors from Syzygium polyanthum (Wight) Walp leaves as revealed by metabolomics and in silico approaches. Journal of Ethnopharmacology 282:114618. doi: 10.1016/j.jep.2021.114618.
   PubMed Web of Science ®Google Scholar
• Tan, B. L., and M. E. Norhaizan. 2021. Oxidative stress, diet and prostate cancer. The World Journal of Men’s Health 39 (2):195–207. doi: 10.5534/wjmh.200014.
   PubMedGoogle Scholar
• Tenfen, A., L. Mariano, T. Boeing, C. C. Cechinel-Zanchett, L. M. da Silva, S. F. de Andrade, P. de Souza, and V. Cechinel-Filho. 2019. Effects of myricetin‐3‐O‐α‐rhamnoside (myricitrin) treatment on urinary parameters of wistar rats. Journal of Pharmacy and Pharmacology 71 (12):1832–8. doi: 10.1111/jphp.13172.
   PubMed Web of Science ®Google Scholar
• Thuan, N. H., R. P. Pandey, T. T. T. Thuy, J. W. Park, and J. K. Sohng. 2013. Improvement of regio-specific production of myricetin-3-O-α-l-rhamnoside in engineered Escherichia coli. Applied Biochemistry and Biotechnology 171 (8):1956–67. doi: 10.1007/s12010-013-0459-9.
   PubMed Web of Science ®Google Scholar
• Tomaz, I., L. Maslov, D. Stupic, D. Preiner, D. Asperger, and J. K. Kontic. 2016. Recovery of flavonoids from grape skins by enzyme-assisted extraction. Separation Science and Technology 51 (2):255–68. doi: 10.1080/01496395.2015.1085881.
   Web of Science ®Google Scholar
• Tsuchiya, S. T., Y. Seo, J. Kohori, R. Ochiai, and A. Suzuki. 2011. Liquid seasoning. United States Patent No.
   Google Scholar
• Tzima, S., I. Georgiopoulou, V. Louli, and K. Magoulas. 2023. Recent advances in supercritical CO2 extraction of pigments, lipids and bioactive compounds from microalgae. Molecules 28 (3):1410. doi: 10.3390/molecules28031410.
   PubMed Web of Science ®Google Scholar
• Uwineza, P. A., and A. Waśkiewicz. 2020. Recent advances in supercritical fluid extraction of natural bioactive compounds from natural plant materials. Molecules 25 (17):3847. doi: 10.3390/molecules25173847.
   PubMed Web of Science ®Google Scholar
• Vallverdu-Queralt, A., I. Odriozola-Serrano, G. Oms-Oliu, R. M. Lamuela-Raventos, P. Elez-Martinez, and O. Martin-Belloso. 2013. Impact of high-intensity pulsed electric fields on carotenoids profile of tomato juice made of moderate-intensity pulsed electric field-treated tomatoes. Food Chemistry 141 (3):3131–8. doi: 10.1016/j.foodchem.2013.05.150.
   PubMed Web of Science ®Google Scholar
• Vanegas, K. G., B. J. Lehka, and U. H. Mortensen. 2017. SWITCH: A dynamic CRISPR tool for genome engineering and metabolic pathway control for cell factory construction in Saccharomyces cerevisiae. Microbial Cell Factories 16 (1):53. doi: 10.1186/s12934-017-0668-y.
   Google Scholar
• Vermeulen, K., D. R. Van Bockstaele, and Z. N. Berneman. 2003. The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer. Cell Proliferation 36 (3):131–49. doi: 10.1046/j.1365-2184.2003.00266.x.
   PubMed Web of Science ®Google Scholar
• Vinitha, U. G., R. Sathasivam, M. S. Muthuraman, and S. U. Park. 2022. Intensification of supercritical fluid in the extraction of flavonoids: A comprehensive review. Physiological and Molecular Plant Pathology 118:101815. doi: 10.1016/j.pmpp.2022.101815.
   Web of Science ®Google Scholar
• Wang, G., Q. Cui, L. J. Yin, X. Zheng, M. Z. Gao, Y. Meng, and W. Wang. 2019. Efficient extraction of flavonoids from Flos Sophorae Immaturus by tailored and sustainable deep eutectic solvent as green extraction media. Journal of Pharmaceutical and Biomedical Analysis 170:285–94. doi: 10.1016/j.jpba.2018.12.032.
   PubMed Web of Science ®Google Scholar
• Wang, J., R. Ledesma-Amaro, Y. Wei, B. Ji, and X.-J. Ji. 2020. Metabolic engineering for increased lipid accumulation in Yarrowia lipolytica -A review. Bioresource Technology 313:123707. doi: 10.1016/j.biortech.2020.123707.
   PubMed Web of Science ®Google Scholar
• Wang, J. M., P. L. Lian, Q. Yu, J. F. Wei, and W. Y. Kang. 2017. Antithrombotic mechanism of polysaccharides in Blackberry (Rubus spp.) seeds. Food & Nutrition Research 61 (1):1379862. doi: 10.1080/16546628.2017.1379862.
   PubMed Web of Science ®Google Scholar
• Wang, M., G. B. Sun, Y. Y. Du, Y. Tian, P. Liao, X. S. Liu, J. X. Ye, and X. B. Sun. 2017. Myricitrin protects cardiomyocytes from hypoxia/reoxygenation injury: Involvement of heat shock protein 90. Frontiers in Pharmacology 8:353. doi: 10.3389/fphar.2017.00353.
   PubMed Web of Science ®Google Scholar
• Wang, W., H. Shen, J. J. Xie, J. Ling, and H. Lu. 2015. Neuroprotective effect of ginseng against spinal cord injury induced oxidative stress and inflammatory responses. International Journal of Clinical and Experimental Medicine 8 (3):3514–21.
   PubMed Web of Science ®Google Scholar
• Wang, Y.-H., Z.-H. Xuan, S. Tian, G.-R. He, and G.-H. Du. 2013. Myricitrin attenuates 6-hydroxydopamine-induced mitochondrial damage and apoptosis in PC12 cells via inhibition of mitochondrial oxidation. Journal of Functional Foods 5 (1):337–45. doi: 10.1016/j.jff.2012.11.004.
   Web of Science ®Google Scholar
• Wannapinpong, S., K. Srikulnath, A. Thongpan, K. Choowongkomon, and S. Peyachoknagul. 2015. Molecular cloning and characterization of the CHS gene family in turmeric (Curcuma longa Linn.). Journal of Plant Biochemistry and Biotechnology 24 (1):25–33. doi: 10.1007/s13562-013-0232-8.
   Web of Science ®Google Scholar
• Wen, L., Z. Zhang, D.-W. Sun, S. P. Sivagnanam, and B. K. Tiwari. 2020. Combination of emerging technologies for the extraction of bioactive compounds. Critical Reviews in Food Science and Nutrition 60 (11):1826–41. doi: 10.1080/10408398.2019.1602823.
   PubMed Web of Science ®Google Scholar
• Weydert, C. J., and J. J. Cullen. 2010. Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue. Nature Protocols 5 (1):51–66. doi: 10.1038/nprot.2009.197.
   PubMed Web of Science ®Google Scholar
• Won, J. H., S. Y. Park, S. G. Nam, H. J. Park, J. W. Choi, and K. T. Lee. 2005. Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide and cyclooxygenase-2 by chiisanoside via suppression of nuclear factor-kappa B activation in RAW 264.7 macrophage cells. Biological & Pharmaceutical Bulletin 28 (10):1919–24. doi: 10.1248/bpb.28.1919.
   PubMed Web of Science ®Google Scholar
• Wu, C., L. He, Y. Zhang, C. You, X. Li, P. Jiang, and F. Wang. 2023. Separation of flavonoids with significant biological activity from Acacia mearnsii leaves. RSC Advances 13 (13):9119–27. doi: 10.1039/d3ra00209h.
   PubMed Web of Science ®Google Scholar
• Wu, J. H., C. Y. Huang, Y. T. Tung, and S. T. Chang. 2008. Online RP-HPLC-DPPH screening method for detection of radical-scavenging phytochemicals from flowers of Acacia confusa. Journal of Agricultural and Food Chemistry 56 (2):328–32. doi: 10.1021/jf072314c.
   PubMed Web of Science ®Google Scholar
• Xi, J., Z. Li, and Y. Fan. 2021. Recent advances in continuous extraction of bioactive ingredients from food-processing wastes by pulsed electric fields. Critical Reviews in Food Science and Nutrition 61 (10):1738–50. doi: 10.1080/10408398.2020.1765308.
   PubMed Web of Science ®Google Scholar
• Xiang, D., C. G. Wang, W. Q. Wang, C. Y. Shi, W. Xiong, M. D. Wang, and J. G. Fang. 2017. Gastrointestinal stability of dihydromyricetin, myricetin, and myricitrin: An in vitro investigation. International Journal of Food Sciences and Nutrition 68 (6):704–11. doi: 10.1080/09637486.2016.1276518.
   PubMed Web of Science ®Google Scholar
• Xiao, J., T. S. Muzashvili, and M. I. Georgiev. 2014. Advances in the biotechnological glycosylation of valuable flavonoids. Biotechnology Advances 32 (6):1145–56. doi: 10.1016/j.biotechadv.2014.04.006.
   PubMed Web of Science ®Google Scholar
• Xie, P. Y., L. L. Cui, Y. Shan, and W. Y. Kang. 2017. Antithrombotic effect and mechanism of Radix Paeoniae Rubra. BioMed Research International 2017:1–9. doi: 10.1155/2017/9475074.
   Web of Science ®Google Scholar
• Xu, R., Y. Zhang, X. Ye, S. Xue, J. Shi, J. Pan, Q. J. F, and C. Chen. 2013. Inhibition effects and induction of apoptosis of flavonoids on the prostate cancer cell line PC-3 in vitro. Food Chemistry 138 (1):48–53. doi: 10.1016/j.foodchem.2012.09.102.
   PubMed Web of Science ®Google Scholar
• Xu, Z. M., X. K. Chu, H. B. Jiang, H. Schilling, S. D. Chen, and J. Feng. 2017. Induced dopaminergic neurons: A new promise for Parkinson’s disease. Redox Biology 11:606–12. doi: 10.1016/j.redox.2017.01.009.
   PubMed Web of Science ®Google Scholar
• Yamada, Y., N. Yoshimi, Y. Hirose, K. Kawabata, K. Matsunaga, M. Shimizu, A. Hara, and H. Mori. 2000. Frequent beta-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis. Cancer Research 60 (13):3323–7.
   PubMed Web of Science ®Google Scholar
• Yamada, Y., N. Yoshimi, Y. Hirose, K. Matsunaga, M. Katayama, K. Sakata, M. Shimizu, T. Kuno, and H. Mori. 2001. Sequential analysis of morphological and biological properties of beta-catenin-accumulated crypts, provable premalignant lesions independent of aberrant crypt foci in rat colon carcinogenesis. Cancer Research 61 (5):1874–8.
   PubMed Web of Science ®Google Scholar
• Yan, L.-G., L. He, and J. Xi. 2017. High intensity pulsed electric field as an innovative technique for extraction of bioactive compounds-A review. Critical Reviews in Food Science and Nutrition 57 (13):2877–88. doi: 10.1080/10408398.2015.1077193.
   PubMed Web of Science ®Google Scholar
• Yan, Z. J., Z. Lin, Y. F. Wu, J. D. Zhan, W. H. Qi, J. Lin, J. Q. Shen, X. H. Xue, and X. Y. Pan. 2020. The protective effect of myricitrin in osteoarthritis: An in vitro and in vivo study. International Immunopharmacology 84:106511. doi: 10.1016/j.intimp.2020.106511.
   PubMed Web of Science ®Google Scholar
• Yang, W.-B., J.-C. Liu, H. Liu, C.-L. Zhang, Z.-Z. Lv, and Z.-G. Jiao. 2019. Optimization of supercritical fluid extraction of phenolic compounds from peach blossom (Amygdalus persica) by response surface methodology. Current Topics in Nutraceutical Research 17 (2):180–7.
   Web of Science ®Google Scholar
• Yang, Y.-L., M. Liu, X. Cheng, W.-H. Li, S.-S. Zhang, Y.-H. Wang, and G.-H. Du. 2019. Myricitrin blocks activation of NF-kappa B and MAPK signaling pathways to protect nigrostriatum neuron in LPS-stimulated mice. Journal of Neuroimmunology 337:577049. doi: 10.1016/j.jneuroim.2019.577049.
   PubMed Web of Science ®Google Scholar
• Yildiz, A., S. Guleryuz, D. P. Ankerst, D. Ongur, and P. F. Renshaw. 2008. Protein kinase C inhibition in the treatment of mania. Archives of General Psychiatry 65 (3):255–63. doi: 10.1001/archgenpsychiatry.2007.43.
   PubMed Web of Science ®Google Scholar
• Yin, Y. C., X. D. Zhang, Z. Q. Gao, T. Hu, and Y. Liu. 2019. The research progress of chalcone isomerase (CHI) in plants. Molecular Biotechnology 61 (1):32–52. doi: 10.1007/s12033-018-0130-3.
   PubMed Web of Science ®Google Scholar
• You, K., H. Gu, Z. W. Yuan, and X. W. Xu. 2021. Tumor necrosis factor alpha signaling and organogenesis. Frontiers in Cell and Developmental Biology 9:727075. doi: 10.3389/fcell.2021.727075.
   PubMed Web of Science ®Google Scholar
• Zarate, C. A., J. B. Singh, P. J. Carlson, J. Quiroz, L. Jolkovsky, D. A. Luckenbaugh, and H. K. Manji. 2007. Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study. Bipolar Disorders 9 (6):561–70. doi: 10.1111/j.1399-5618.2007.00530.x.
   PubMed Web of Science ®Google Scholar
• Zhang, B., Y. P. Chen, Q. Shen, G. Y. Liu, J. X. Ye, G. B. Sun, and X. B. Sun. 2016. Myricitrin attenuates high glucose-induced apoptosis through activating Akt-Nrf2 signaling in H9c2 cardiomyocytes. Molecules 21 (7):880. doi: 10.3390/molecules21070880.
   PubMed Web of Science ®Google Scholar
• Zhang, B., Q. Shen, Y. P. Chen, R. L. Pan, S. H. Kuang, G. Y. Liu, G. B. Sun, and X. B. Sun. 2017. Myricitrin alleviates oxidative stress-induced inflammation and apoptosis and protects mice against diabetic cardiomyopathy. Scientific Reports 7 (1):44239. doi: 10.1038/srep44239.
   Google Scholar
• Zhang, C., X. Lyu, R. N. Arshad, R. M. Aadil, Y. Tong, W. Zhao, and R. Yang. 2023. Pulsed electric field as a promising technology for solid foods processing: A review. Food Chemistry 403:134367. doi: 10.1016/j.foodchem.2022.134367.
   PubMed Web of Science ®Google Scholar
• Zhang, H.-F., X.-H. Yang, and Y. Wang. 2011. Microwave assisted extraction of secondary metabolites from plants: Current status and future directions. Trends in Food Science & Technology 22 (12):672–88. doi: 10.1016/j.tifs.2011.07.003.
   Web of Science ®Google Scholar
• Zhang, Q. J. P. 2021. Insulin-mimic components in acer truncatum leaves: Bio-guided isolation, annual variance profiling and regulating pathway investigated by omics. Pharmaceuticals (Basel) 14 (7):662.
   PubMedGoogle Scholar
• Zhang, W. J., C. Torres-Rojas, J. M. Yue, and B. M. Zhu. 2021. Adipose-derived stem cells in ovarian cancer progression, metastasis, and chemoresistance. Experimental Biology and Medicine (Maywood, N.J.) 246 (16):1810–5. doi: 10.1177/15353702211023846.
   PubMed Web of Science ®Google Scholar
• Zhang, X. Y., Y. H. Liu, D. Z. Liu, J. Y. Xu, and Q. Zhang. 2021. Insulin-mimic components in Acer truncatum Leaves: Bio-guided isolation, annual variance profiling and regulating pathway investigated by omics. Pharmaceuticals 14 (7):662. doi: 10.3390/ph14070662.
   Web of Science ®Google Scholar
• Zhang, Y., S. G. Chen, C. Y. Wei, G. O. Rankin, X. Q. Ye, and Y. C. Chen. 2018. Flavonoids from Chinese bayberry leaves induced apoptosis and G1 cell cycle arrest via Erk pathway in ovarian cancer cells. European Journal of Medicinal Chemistry 147:218–26. doi: 10.1016/j.ejmech.2018.01.084.
   PubMed Web of Science ®Google Scholar
• Zhao, M. R., J. Li, L. Zhu, P. Chang, L. L. Li, and L. Y. Zhang. 2019. Identification and characterization of MYB-bHLH-WD40 regulatory complex members controlling anthocyanidin biosynthesis in blueberry fruits development. Genes 10(7):496. doi: 10.3390/genes10070496.
   PubMed Web of Science ®Google Scholar
• Zhou, M., O. A. Fakayode, M. Ren, H. Li, J. Liang, and C. Zhou. 2023. Green and sustainable extraction of lignin by deep eutectic solvent, its antioxidant activity, and applications in the food industry. Critical Reviews in Food Science and Nutrition :1–19. doi: 10.1080/10408398.2023.2181762.
   Web of Science ®Google Scholar