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Leukemia & Lymphoma Volume 61, 2020 - Issue 13
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Letters to the Editor

Renal pathology in patients with monoclonal gammopathy or multiple myeloma: monoclonal immunoglobulins are not always the cause

Efstathios Kastritisa Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, GreeceCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8191-5832
ORCID Icon,
Nikolaos Kanelliasa Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Foteini Theodorakakoua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Erasmia Psimenoua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Charikleia Gakiopouloub 1st Department of Pathology, National and Kapodistrian University of Athens, Athens, Greece
,
Smaragdi Marinakic Nephrology Unit, ‘Laikon’ Hospital, National and Kapodistrian University of Athens, Athens, Greece
,
Maria Roussoua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Maria Gavriatopouloua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, GreeceORCID Iconhttps://orcid.org/0000-0002-6244-1229
ORCID Icon,
Magdalini Migkoua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Despina Fotioua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, GreeceORCID Iconhttps://orcid.org/0000-0002-0618-8900
ORCID Icon,
Evangelos Eleutherakis-Papaiakovoua Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Panagiotis Malandrakisa Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
,
Evangelos Terposa Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, GreeceORCID Iconhttps://orcid.org/0000-0001-5133-1422
ORCID Icon &
Meletios A. Dimopoulosa Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, GreeceORCID Iconhttps://orcid.org/0000-0001-8990-3254
ORCID Icon show all
Pages 3247-3250 | Received 05 Apr 2020, Accepted 10 Jul 2020, Published online: 27 Jul 2020

References

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  • Sethi S, Rajkumar SV, D'Agati VD. The complexity and heterogeneity of monoclonal immunoglobulin-associated renal diseases. J Am Soc Nephrol. 2018;29(7):1810–1823.
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  • Leung N, Gertz M, Kyle RA, et al. Urinary albumin excretion patterns of patients with cast nephropathy and other monoclonal gammopathy-related kidney diseases. CJASN. 2012;7(12):1964–1968.
  • Hutchison CA, Cockwell P, Moroz V, et al. High cutoff versus high-flux haemodialysis for myeloma cast nephropathy in patients receiving bortezomib-based chemotherapy (EuLITE): a phase 2 randomised controlled trial. Lancet Haematol. 2019;6(4):e217–e228.
  • Bridoux F, Carron PL, Pegourie B, et al. Effect of high-cutoff hemodialysis vs conventional hemodialysis on hemodialysis independence among patients with myeloma cast nephropathy: a randomized clinical trial. JAMA. 2017;318(21):2099–2110.
  • Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15(12):e538-48–e548.
  • Kastritis E, Papassotiriou I, Merlini G, et al. Growth differentiation factor-15 is a new biomarker for survival and renal outcomes in light chain amyloidosis. Blood. 2018;131(14):1568–1575.
  • Papassotiriou GP, Kastritis E, Gkotzamanidou M, et al. Neutrophil gelatinase–associated lipocalin and cystatin c are sensitive markers of renal injury in patients with multiple myeloma. Clin Lymphoma Myeloma Leuk. 2016;16(1):29–35.
  • Terpos E, Christoulas D, Kastritis E, et al. The Chronic Kidney Disease Epidemiology Collaboration cystatin C (CKD-EPI-CysC) equation has an independent prognostic value for overall survival in newly diagnosed patients with symptomatic multiple myeloma; is it time to change from MDRD to CKD-EPI-CysC equations? Eur J Haematol. 2013;91(4):347–355.
  • Fermand JP, Bridoux F, Kyle RA, et al. How I treat monoclonal gammopathy of renal significance (MGRS). Blood. 2013;122(22):3583–3590.

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