Self-assembled dihydroartemisinin nanoparticles as a platform for cervical cancer chemotherapy

References

• Acharya S, Sahoo SK. (2011). PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect. Adv Drug Deliv Rev 63:170–83.
   PubMed Web of Science ®Google Scholar
• Boardman CH, Brady WE, Dizon DS, et al. (2018). A phase I evaluation of extended field radiation therapy with concomitant cisplatin chemotherapy followed by paclitaxel and carboplatin chemotherapy in women with cervical carcinoma metastatic to the para-aortic lymph nodes: an NRG Oncology/Gynecologic Oncology Group Study. Gynecol Oncol 151:202–7.
   PubMed Web of Science ®Google Scholar
• Chen W, Zheng R, Baade PD, et al. (2016). Cancer statistics in China, 2015. CA Cancer J Clin 66:115–32.
   PubMed Web of Science ®Google Scholar
• Danafar H, Davaran S, Rostamizadeh K, et al. (2014). Biodegradable m-PEG/PCL core–shell micelles: preparation and characterization as a sustained release formulation for curcumin. Adv Pharm Bull 4:501–10.
   PubMedGoogle Scholar
• Dell'Eva R, Pfeffer U, Vené R, et al. (2004). Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate. Biochem Pharmacol 68:2359–66.
   PubMed Web of Science ®Google Scholar
• Duan X, Chan C, Han W, et al. (2019). Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nat Commun 10:1899–913.
   PubMed Web of Science ®Google Scholar
• Farokhzad OC, Jon S, Khademhosseini A, et al. (2004). Nanoparticle–aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res 64:7668–72.
   PubMed Web of Science ®Google Scholar
• Gong C, Xie Y, Wu Q, et al. (2012). Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma. Nanoscale 4:6004–17.
   PubMed Web of Science ®Google Scholar
• Gou ML, Men K, Shi HS, et al. (2011). Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo. Nanoscale 3:1558–67.
   PubMed Web of Science ®Google Scholar
• Gou ML, Zheng XL, Men K, et al. (2009). Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles. Pharm Res 26:2164–73.
   PubMed Web of Science ®Google Scholar
• Jiang Z, Zhu Z, Liu C, et al. (2008). Non-enzymatic and enzymatic degradation of poly(ethylene glycol)-b-poly-(ε-caprolactone) diblock copolymer micelles in aqueous solution. Polymer 49:5513–9.
   Web of Science ®Google Scholar
• Kumar R, Singh M, Meena J, et al. (2019). Hyaluronic acid–dihydroartemisinin conjugate: synthesis, characterization and in vitro evaluation in lung cancer cells. Int J Biol Macromol 133:495–502.
   PubMed Web of Science ®Google Scholar
• Li H, Li X, Shi X, et al. (2019). Effects of magnetic dihydroartemisinin nano-liposome in inhibiting the proliferation of head and neck squamous cell carcinomas. Phytomedicine 56:215–28.
   PubMed Web of Science ®Google Scholar
• Lin R, Zhang Z, Chen L, et al. (2016). Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells. Cancer Lett 381:165–75.
   PubMed Web of Science ®Google Scholar
• Liu JJ, Tang W, Fu M, et al. (2019). Development of R8 modified epirubicin-dihydroartemisinin liposomes for treatment of non-small-cell lung cancer. Artif Cells Nanomed Biotechnol 47:1947–60.
   PubMed Web of Science ®Google Scholar
• Liu K, Dai L, Li C, et al. (2016). Self-assembled targeted nanoparticles based on transferrin-modified eight-arm-polyethylene glycol-dihydroartemisinin conjugate. Sci Rep 6:29461.
   PubMed Web of Science ®Google Scholar
• Liu L, Wei Y, Zhai S, et al. (2015). Dihydroartemisinin and transferrin dual-dressed nano-graphene oxide for a pH-triggered chemotherapy. Biomaterials 62:35–46.
   PubMed Web of Science ®Google Scholar
• Liu Y, Gao S, Zhu J, et al. (2018a). Dihydroartemisinin induces apoptosis and inhibits proliferation, migration, and invasion in epithelial ovarian cancer via inhibition of the hedgehog signaling pathway. Cancer Med 7:5704–15.
   PubMed Web of Science ®Google Scholar
• Liu Y, Liu K, Li X, et al. (2018b). A novel self-assembled nanoparticle platform based on pectin-eight-arm polyethylene glycol–drug conjugates for co-delivery of anticancer drugs. Mater Sci Eng C Mater Biol Appl 86:28–41.
   PubMed Web of Science ®Google Scholar
• Lu ZH, Peng JH, Zhang RX, et al. (2018). Dihydroartemisinin inhibits colon cancer cell viability by inducing apoptosis through up-regulation of PPARγ expression. Saudi J Biol Sci 25:372–6.
   PubMed Web of Science ®Google Scholar
• Ma W, Xu A, Ying J, et al. (2015). Biodegradable core–shell copolymer-phospholipid nanoparticles for combination chemotherapy: an in vitro study. J Biomed Nanotechnol 11:1193–200.
   PubMed Web of Science ®Google Scholar
• Qiu JF, Gao X, Wang BL, et al. (2013). Preparation and characterization of monomethoxy poly(ethylene glycol)–poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin. Int J Nanomedicine 8:3061–9.
   PubMed Web of Science ®Google Scholar
• Shi S, Zhu X, Guo Q, et al. (2012). Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro. Int J Nanomedicine 7:1749–59.
   PubMed Web of Science ®Google Scholar
• Sun Q, Teong B, Chen IF, et al. (2014). Enhanced apoptotic effects of dihydroartemisinin-aggregated gelatin and hyaluronan nanoparticles on human lung cancer cells. J Biomed Mater Res B Appl Biomater 102:455–62.
   PubMed Web of Science ®Google Scholar
• Wan X, Zhong H, Pan W, et al. (2019). Programmed release of dihydroartemisinin for synergistic cancer therapy using a CaCO3 mineralized metal-organic framework. Angew Chem Int Ed Engl 58:14134–9.
   PubMed Web of Science ®Google Scholar
• Wang D, Zhou J, Chen R, et al. (2016a). Magnetically guided delivery of DHA and Fe ions for enhanced cancer therapy based on pH-responsive degradation of DHA-loaded Fe3O4@C@MIL-100(Fe) nanoparticles. Biomaterials 107:88–101.
   PubMed Web of Science ®Google Scholar
• Wang L, Li J, Shi X, et al. (2019a). Antimalarial dihydroartemisinin triggers autophagy within HeLa cells of human cervical cancer through Bcl-2 phosphorylation at Ser70. Phytomedicine 52:147–56.
   PubMed Web of Science ®Google Scholar
• Wang L, Wang Y, Wang X, et al. (2016b). Encapsulation of low lipophilic and slightly water-soluble dihydroartemisinin in PLGA nanoparticles with phospholipid to enhance encapsulation efficiency and in vitro bioactivity. J Microencapsul 33:43–52.
   PubMed Web of Science ®Google Scholar
• Wang Y, Pang XL, Luo J, et al. (2019b). Naproxen nanoparticle-loaded thermosensitive chitosan hydrogel for prevention of postoperative adhesions. ACS Biomater Sci Eng 5:1580–8.
   PubMed Web of Science ®Google Scholar
• Wang Y, Yu H, Zhang Y, et al. (2013). Emodin induces apoptosis of human cervical cancer HeLa cells via intrinsic mitochondrial and extrinsic death receptor pathway. Cancer Cell Int 13:71.
   PubMed Web of Science ®Google Scholar
• Wang Z, Duan X, Lv Y, et al. (2019c). Low density lipoprotein receptor (LDLR)-targeted lipid nanoparticles for the delivery of sorafenib and Dihydroartemisinin in liver cancers. Life Sci 239:117013.
   PubMed Web of Science ®Google Scholar
• Wu GS, Lu JJ, Guo JJ, et al. (2013). Synergistic anti-cancer activity of the combination of dihydroartemisinin and doxorubicin in breast cancer cells. Pharmacol Rep 65:453–9.
   PubMed Web of Science ®Google Scholar
• Wu M, Liu J, Hu C, et al. (2018). Olaparib nanoparticles potentiated radiosensitization effects on lung cancer. Int J Nanomedicine 13:8461–72.
   PubMed Web of Science ®Google Scholar
• Xu Z, Liu S, Kang Y, et al. (2015). Glutathione- and pH-responsive nonporous silica prodrug nanoparticles for controlled release and cancer therapy. Nanoscale 7:5859–68.
   PubMed Web of Science ®Google Scholar
• You H, Fu S, Qin X, et al. (2016). A study of the synergistic effect of folate-decorated polymeric micelles incorporating hydroxycamptothecin with radiotherapy on xenografted human cervical carcinoma. Colloids Surf B Biointerfaces 140:150–60.
   PubMed Web of Science ®Google Scholar
• Yu Y, Xu S, You H, et al. (2017). In vivo synergistic anti-tumor effect of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma. Drug Deliv 24:75–82.
   PubMed Web of Science ®Google Scholar
• Zhang CZ, Zhang H, Yun J, et al. (2012). Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo. Biochem Pharmacol 83:1278–89.
   PubMed Web of Science ®Google Scholar
• Zhang H, Jiang Y, Ni X, et al. (2018). Glycyrrhetinic acid-modified norcantharidin nanoparticles for active targeted therapy of hepatocellular carcinoma. J Biomed Nanotechnol 14:114–26.
   PubMed Web of Science ®Google Scholar
• Zhang T, Hu Y, Wang T, et al. (2017). Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation. Int J Mol Med 40:21–30.
   PubMed Web of Science ®Google Scholar
• Zhang X, Liu J, Qiao H, et al. (2010). Formulation optimization of dihydroartemisinin nanostructured lipid carrier using response surface methodology. Powder Technol 197:120–8.
   Web of Science ®Google Scholar
• Zheng X, Kan B, Gou M, et al. (2010). Preparation of MPEG-PLA nanoparticle for honokiol delivery in vitro. Int J Pharm 386:262–7.
   PubMed Web of Science ®Google Scholar
• Zhu H, Liao SD, Shi JJ, et al. (2014). DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal. Free Radic Biol Med 71:121–32.
   PubMed Web of Science ®Google Scholar