2,996
Views
48
CrossRef citations to date
0
Altmetric
Research Article

Co-delivery of doxorubicin and paclitaxel by reduction/pH dual responsive nanocarriers for osteosarcoma therapy

, , &
Pages 1044-1053 | Received 28 Apr 2020, Accepted 16 Jun 2020, Published online: 07 Jul 2020

References

  • Anderson ME. (2016). Update on survival in osteosarcoma. Orthop Clin North Am 47:283–92.
  • Baabur-Cohen H, Vossen LI, Kruger HR, et al. (2017). In vivo comparative study of distinct polymeric architectures bearing a combination of paclitaxel and doxorubicin at a synergistic ratio. J Control Release 257:118–31.
  • Chakravarthi S, Bulleid NJ. (2004). Glutathione is required to regulate the formation of native disulfide bonds within proteins entering the secretory pathway. J Biol Chem 279:39872–9.
  • Chen H, Tham HP, Ang CY, et al. (2016). Responsive prodrug self-assembled vesicles for targeted chemotherapy in combination with intracellular imaging. ACS Appl Mater Interf 8:24319–24.
  • Chen W, Achazi K, Schade B, Haag R. (2015). Charge-conversional and reduction-sensitive poly(vinyl alcohol) nanogels for enhanced cell uptake and efficient intracellular doxorubicin release. J Control Release 205:15–24.
  • Cheng R, Feng F, Meng F, et al. (2011). Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery. J Control Release 152:2–12.
  • Chiper M, Niederreither K, Zuber G. (2018). Transduction methods for cytosolic delivery of proteins and bioconjugates into living cells. Adv Healthc Mater 7:e1701040.
  • Chou T-C. (2006). Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58:621–81.
  • Eldar-Boock A, Polyak D, Scomparin A, Satchi-Fainaro R. (2013). Nano-sized polymers and liposomes designed to deliver combination therapy for cancer. Curr Opin Biotechnol 24:682–9.
  • Fan W, Yung B, Huang P, Chen X. (2017). Nanotechnology for multimodal synergistic cancer therapy. Chem Rev 117:13566–638.
  • Feng C, Zhang H, Chen J, et al. (2019). Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer. Int J Pharm 560:191–204.
  • Fu A, Tang R, Hardie J, et al. (2014). Promises and pitfalls of intracellular delivery of proteins. Bioconjug Chem 25:1602–8.
  • Gao L, Wang T, Jia K, et al. (2017). Glucose-responsive supramolecular vesicles based on water-soluble pillar[5]arene and pyridylboronic acid derivatives for controlled insulin delivery. Chemistry 23:6605–14.
  • Giantonio BJ, Catalano PJ, Meropol NJ, et al. (2007). Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the eastern cooperative oncology group study E3200. J Clin Oncol 25:1539–44.
  • Hao Q, Chen Y, Huang Z, et al. (2018). Supramolecular chemotherapy: carboxylated pillar[6]arene for decreasing cytotoxicity of oxaliplatin to normal cells and improving its anticancer bioactivity against colorectal cancer. ACS Appl Mater Interf 10:5365–72.
  • Harrison DJ, Geller DS, Gill JD, et al. (2018). Current and future therapeutic approaches for osteosarcoma. Expert Rev Anticancer Ther 18:39–50.
  • He C, Tang Z, Tian H, Chen X. (2016). Co-delivery of chemotherapeutics and proteins for synergistic therapy. Adv Drug Deliv Rev 98:64–76.
  • Heymann MF, Brown HK, Heymann D. (2016). Drugs in early clinical development for the treatment of osteosarcoma. Expert Opin Investig Drugs 25:1265–80.
  • Hoffman AS. (2013). Stimuli-responsive polymers: biomedical applications and challenges for clinical translation. Adv Drug Deliv Rev 65:10–6.
  • Hu X, Zhang Y, Xie Z, et al. (2017). Stimuli-responsive polymersomes for biomedical applications. Biomacromolecules 18:649–73.
  • Huang H, Zhang X, Yu J, et al. (2013). Fabrication and reduction-sensitive behavior of polyion complex nano-micelles based on PEG-conjugated polymer containing disulfide bonds as a potential carrier of anti-tumor paclitaxel. Coll Surf B Biointerf 110:59–65.
  • Jackson TM, Bittman M, Granowetter L. (2016). Pediatric malignant bone tumors: a review and update on current challenges, and emerging drug targets. Curr Probl Pediatr Adolesc Health Care 46:213–28.
  • Ji GR, Yu NC, Xue X, Li ZG. (2015). PERK-mediated autophagy in osteosarcoma cells resists ER stress-induced cell apoptosis. Int J Biol Sci 11:803–12.
  • Jiang T, Mo R, Bellotti A, et al. (2014). Gel–liposome-mediated co-delivery of anticancer membrane-associated proteins and small-molecule drugs for enhanced therapeutic efficacy. Adv Funct Mater 24:2295–304.
  • Jiang Y, Zhou Y, Zhang CY, Fang T. (2020). Co-delivery of paclitaxel and doxorubicin by pH-responsive prodrug micelles for cancer therapy. Int J Nanomed 15:3319–31.
  • Jin C, Li H, He Y, et al. (2010). Combination chemotherapy of doxorubicin and paclitaxel for hepatocellular carcinoma in vitro and in vivo. J Cancer Res Clin Oncol 136:267–74.
  • Kamaly N, Yameen B, Wu J, Farokhzad OC. (2016). Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release. Chem Rev 116:2602–63.
  • Landesman-Milo D, Ramishetti S, Peer D. (2015). Nanomedicine as an emerging platform for metastatic lung cancer therapy. Cancer Metastasis Rev 34:291–301.
  • Leader B, Baca QJ, Golan DE. (2008). Protein therapeutics: a summary and pharmacological classification. Nat Rev Drug Discov 7:21–39.
  • Li Y, Yang H, Yao J, et al. (2018). Glutathione-triggered dual release of doxorubicin and camptothecin for highly efficient synergistic anticancer therapy. Coll Surf B Biointerf 169:273–9.
  • Liu Y, Fang J, Kim Y-J, et al. (2014). Codelivery of doxorubicin and paclitaxel by cross-linked multilamellar liposome enables synergistic antitumor activity. Mol Pharm 11:1651–61.
  • Lu S, Zhao F, Zhang Q, Chen P. (2018). Therapeutic peptide amphiphile as a drug carrier with ATP-triggered release for synergistic effect, improved therapeutic index, and penetration of 3D cancer cell spheroids. Int J Mol Sci 19:2773.
  • Mo J, Wang L, Huang X, et al. (2017). Multifunctional nanoparticles for co-delivery of paclitaxel and carboplatin against ovarian cancer by inactivating the JMJD3-HER2 axis. Nanoscale 9:13142–52.
  • Park J, Wrzesinski SH, Stern E, et al. (2012). Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy. Nat Mater 11:895–905.
  • Qiu Y, Wu C, Jiang J, et al. (2017). Lipid-coated hollow mesoporous silica nanospheres for co-delivery of doxorubicin and paclitaxel: preparation, sustained release, cellular uptake and pharmacokinetics. Mater Sci Eng C Mater Biol Appl 71:835–43.
  • Ramasamy T, Ruttala HB, Choi JY, et al. (2015). Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan. Chem Commun 51:5758–61.
  • Samanta K, Setua S, Kumari S, et al. (2019). Gemcitabine combination nano therapies for pancreatic cancer. Pharmaceutics 11:574.
  • Torchilin V. (2011). Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 63:131–5.
  • Wang H, Wu J, Williams GR, et al. (2019). Platelet-membrane-biomimetic nanoparticles for targeted antitumor drug delivery. J Nanobiotechnol 17:60.
  • Wang H, Zhao Y, Wu Y, et al. (2011). Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles. Biomaterials 32:8281–90.
  • Wang Y, Zhang H, Hao J, et al. (2016). Lung cancer combination therapy: co-delivery of paclitaxel and doxorubicin by nanostructured lipid carriers for synergistic effect. Drug Deliv 23:1398–403.
  • Wu C, Xu J, Hao Y, et al. (2017). Application of a lipid-coated hollow calcium phosphate nanoparticle in synergistic co-delivery of doxorubicin and paclitaxel for the treatment of human lung cancer A549 cells. Int J Nanomed 12:7979–92.
  • Wu X, Sun X, Guo Z, et al. (2014). In vivo and in situ tracking cancer chemotherapy by highly photostable NIR fluorescent theranostic prodrug. J Am Chem Soc 136:3579–88.
  • Xiaoya D, Yu W, Gao L, et al. (2019). Iminoboronate ester cross-linked hydrogels with injectable, self-healing and multi-responsive properties. Acta Polymerica Sinica 50:505–15.
  • Xu XD, Zhao L, Qu Q, et al. (2015). Imaging-guided drug release from glutathione-responsive supramolecular porphysome nanovesicles. ACS Appl Mater Interf 7:17371–80.
  • Yamawaki K, Asoh TA, Kikuchi A. (2016). Redox-responsive minimized fragmentation of three-armed oligo(ethylene glycol) gels for protein release. Coll Surf B Biointerf 146:343–51.
  • Yang H, Shen W, Liu W, et al. (2018). PEGylated poly(α-lipoic acid) loaded with doxorubicin as a pH and reduction dual responsive nanomedicine for breast cancer therapy. Biomacromolecules 19:4492–503.
  • Yang M, Ding H, Zhu Y, et al. (2019). Co-delivery of paclitaxel and doxorubicin using mixed micelles based on the redox sensitive prodrugs. Coll Surf B Biointerf 175:126–35.
  • Zhang Y, Xiao CS, Li MQ, et al. (2014). Core-cross-linked micellar nanoparticles from a linear-dendritic prodrug for dual-responsive drug delivery. Polym Chem 5:2801–8.
  • Zhao D, Wu J, Li C, et al. (2017). Precise ratiometric loading of PTX and DOX based on redox-sensitive mixed micelles for cancer therapy. Coll Surf B Biointerf 155:51–60.
  • Zhao L, Zhu L, Liu F, et al. (2011). pH triggered injectable amphiphilic hydrogel containing doxorubicin and paclitaxel. Int J Pharma 410:83–91.