Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line

References

• Brubach JB, Jannin V, Mahler B, Bourgaux C, Lessieur P, Roy P, Ollivon M. 2007. Structural and thermal characterization of glyceryl behenate by X-ray diffraction coupled to differential calorimetry and infrared spectroscopy. Int J Pharm. 336:248–256.
   PubMed Web of Science ®Google Scholar
• Bunjes H. Koch MHJ, Westesen K. 2002. Effects of surfactants on the crystallization and polymorphism of lipid nanoparticles, Prog. Colloid Polym Sci. 121:7–10.
   Google Scholar
• Chawla V, Saraf SA. 2011. Glyceryl Behenate and its suitability for production of aceclofenac solid lipid nanoparticles. J Am Oil Chem Soc. 88:119–126.
   Web of Science ®Google Scholar
• Doktorovova S, Kovacevic AB, Garcia ML, Souto EB. 2016. Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: current evidence from in vitro and in vivo evaluation. Eur J Pharm Biopharm. 108:235–252.
   PubMed Web of Science ®Google Scholar
• Doktorovova S, Shegokar R, Fernandes L, Martins-Lopes P, Silva AM, Müller RH, Souto EB. 2014. Trehalose is not a universal solution for solid lipid nanoparticles freeze-drying. Pharma Develop Technol. 19:922–929.
   PubMed Web of Science ®Google Scholar
• Fangueiro JF, Andreani T, Egea MA, Garcia ML, Souto SB, Silva AM, Souto EB. 2014a. Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity. International Journal of Pharmaceutics. 461:64–73.
   PubMed Web of Science ®Google Scholar
• Fangueiro JF, Andreani T, Fernandes L, Garcia ML, Egea MA, Silva AM, Souto EB. 2014b. Physicochemical characterization of epigallocatechin gallate lipid nanoparticles (EGCG-LNs) for ocular instillation. Coll Surf B Biointer. 123:452–460.
   PubMed Web of Science ®Google Scholar
• Fangueiro JF, Calpena AC, Clares B, Andreani T, Egea MA, Veiga FJ, Garcia ML, Silva AM, Souto EB. 2016. Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): in vivo, in vitro and ex vivo studies. Int J Pharma. 502:161–169.
   PubMed Web of Science ®Google Scholar
• Freitas C, Müller RH. 1999. Correlation between log-term stability of solid lipid nanoparticles (SLN™) and crystallinity of the lipid phase. Eur J Pharm Biopharm. 47:125–132.
   PubMed Web of Science ®Google Scholar
• Hossin B, Rizi K, Murdan S. 2016. Application of hansen solubility parameters to predict drug-nail interactions, which can assist the design of nail medicines. Eur J Pharma Biopharma. 102:32–40.
   PubMed Web of Science ®Google Scholar
• Huerta C, Aberturas M. d R, Molpeceres J. 2015. Nimesulide-loaded nanoparticles for the potential coadjuvant treatment of prostate cancer. Int J Pharm. 493:152–160.
   PubMed Web of Science ®Google Scholar
• Knapik J, Wojnarowska Z, Grzybowska K, Tajber L, Mesallati H, Paluch KJ, Paluch M. 2016. Molecular dynamics and physical stability of amorphous nimesulide drug and its binary drug-polymer systems. Mol Pharma. 13:1937–1946.
   PubMed Web of Science ®Google Scholar
• Liu M, Wang RY. 2015. Size-dependent melting behavior of colloidal In, Sn, and Bi nanocrystals. Sci Rep. 5:16353.
   PubMed Web of Science ®Google Scholar
• Martins S, Tho I, Reimold I, Fricker G, Souto E, Ferreira D, Brandl M. 2012. Brain delivery of camptothecin by means of solid lipid nanoparticles: formulation design, in vitro and in vivo studies. Int J Pharma. 439:49–62.
   PubMed Web of Science ®Google Scholar
• Prosapio V, Reverchon E, De Marco I. 2016. Formation of PVP/nimesulide microspheres by supercritical antisolvent coprecipitation. J Supercritical Fluids. 118:19–26.
   Web of Science ®Google Scholar
• Severino P, Andreani T, Jager A, Chaud MV, Santana MH, Silva AM, Souto EB. 2014. Solid lipid nanoparticles for hydrophilic biotech drugs: optimization and cell viability studies (Caco-2 & HEPG-2 cell lines). Eur J Med Chem. 81:28–34.
   PubMed Web of Science ®Google Scholar
• Severino P, Chaud MV, Shimojo A, Antonini D, Lancelloti M, Santana MH, Souto EB. 2015. Sodium alginate-cross-linked polymyxin B sulphate-loaded solid lipid nanoparticles: Antibiotic resistance tests and HaCat and NIH/3T3 cell viability studies. Coll Surf B Biointer. 129:191–197.
   PubMed Web of Science ®Google Scholar
• Severino P, Pinho SC, Souto EB, Santana MH. 2011. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. Coll Surf B Biointer. 86:125–130.
   PubMed Web of Science ®Google Scholar
• Severino P, Santana MH, Souto EB. 2012. Optimizing SLN and NLC by 2(2) full factorial design: effect of homogenization technique. Mat Sci Eng C Mater Biol Appl. 32:1375–1379.
   PubMed Web of Science ®Google Scholar
• Shah RM, Eldridge DS, Palombo EA, Harding IH. 2016. Microwave-assisted formulation of solid lipid nanoparticles loaded with non-steroidal anti-inflammatory drugs. Int J Pharma. 515:543–554.
   PubMed Web of Science ®Google Scholar
• Siekmann B, Westesen K. 1998. Submicron lipid suspensions (Solid lipid nanoparticles) versus lipid nanoemulsions: similarities and differences. In: Benita S, editor. Submicron emulsions in drug targeting and delivery. Amsterdam: Harwood Academic Publishers; p. 205–218.
   Google Scholar
• Sousa R, Pereira I, Boonme P, Vieira V, Fangueiro JF, Santos AC, Souto EB. 2017. Nimesulide-Loaded Solid Lipid Nanoparticles (SLN): Pre-Formulation Studies Based on Hansen Solubility Parameters (HSP), International Conference in Poznań, Faculty of Biology. April 2017. p. 6–8.
   Google Scholar
• Souto EB, Almeida AJ, Müller RH. 2007. Lipid nanoparticles (SLN®, NLC®) for cutaneous drug delivery: structure, protection & skin effects. J Biomed Nanotechnol. 3:317–331.
   Web of Science ®Google Scholar
• Souto EB, Muller RH. 2010. Lipid nanoparticles: effect on bioavailability and pharmacokinetic changes. Handbook Exper Pharmacol. 197:115–141.
   PubMedGoogle Scholar
• Souto EB, Wissing SA, Barbosa CM, Muller RH. 2004. Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. Int J Pharma. 278:71–77.
   PubMed Web of Science ®Google Scholar