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Research Articles

Effect of Soluplus on the supersaturation and absorption of tacrolimus formulated as inclusion complex with dimethyl-β-cyclodextrin

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Pages 1076-1082 | Received 14 Nov 2018, Accepted 08 Jun 2019, Published online: 08 Jul 2019

References

  • Alopaeus JF, Hagesaether E, Tho I. 2019. Micellisation mechanism and behaviour of Soluplus®-furosemide micelles: preformulation studies of an oral nanocarrier-based system. Pharmaceuticals (Basel). 12.
  • Arima H, Yunomae K, Miyake K, Irie T, Hirayama F, Uekama K. 2001. Comparative studies of the enhancing effects of cyclodextrins on the solubility and oral bioavailability of tacrolimus in rats. J Pharm Sci. 90:690–701.
  • Brouwers J, Brewster ME, Augustijns P. 2009. Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability? J Pharm Sci. 98:2549–2572.
  • Brouwers J, Geboers S, Mols R, Tack J, Augustijns P. 2017. Gastrointestinal behavior of itraconazole in humans – Part 1: supersaturation from a solid dispersion and a cyclodextrin-based solution. Int J Pharm. 525:211–217.
  • Ding P, Shen H, Wang J, Ju J. 2018. Improved oral bioavailability of magnolol by using a binary mixed micelle system. Artif Cells Nanomed Biotechnol. 46:668–674.
  • Franca MT, Nicolay Pereira R, Kluppel Riekes M, Munari Oliveira Pinto J, Stulzer HK. 2018. Investigation of novel supersaturating drug delivery systems of chlorthalidone: the use of polymer-surfactant complex as an effective carrier in solid dispersions. Eur J Pharm Sci. 111:142–152.
  • Frank DS, Matzger AJ. 2019. Effect of polymer hydrophobicity on the stability of amorphous solid dispersions and supersaturated solutions of a hydrophobic pharmaceutical. Mol Pharm. 16:682–688.
  • Hu X, Lin C, Chen D, Zhang J, Liu Z, Wu W, Song H. 2012. Sirolimus solid self-microemulsifying pellets: formulation development, characterization and bioavailability evaluation. Int J Pharm. 438:123–133.
  • Hu XY, Lou H, Hageman MJ. 2018. Preparation of lapatinib ditosylate solid dispersions using solvent rotary evaporation and hot melt extrusion for solubility and dissolution enhancement. Int J Pharm. 552:154–163.
  • Hughey JR, Keen JM, Miller DA, Kolter K, Langley N, McGinity JW. 2013. The use of inorganic salts to improve the dissolution characteristics of tablets containing Soluplus®-based solid dispersions. Eur J Pharm Sci. 48:758–766.
  • Huo T, Chen X, Zhang Q, Sun K, Zhang M, Tao C, Song H. 2018. Preparation and intestinal absorption studies of tacrolimus cyclodextrin inclusion complexes. Chin J New Drugs. 27:1918–1926.
  • Kalt DA. 2017. Tacrolimus: a review of laboratory detection methods and indications for use. Lab Med. 48:e62–e65.
  • Kawakami K. 2017. Supersaturation and crystallization: non-equilibrium dynamics of amorphous solid dispersions for oral drug delivery. Expert Opin Drug Deliv. 14:735–743.
  • Kulkarni C, Kelly AL, Gough T, Jadhav V, Singh KK, Paradkar A. 2018. Application of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug. Drug Dev Ind Pharm. 44:206–214.
  • Medarevic D, Kachrimanis K, Djuric Z, Ibric S. 2015. Influence of hydrophilic polymers on the complexation of carbamazepine with hydroxypropyl-β-cyclodextrin . Eur J Pharm Sci. 78:273–285.
  • Nguyen TVA, Yoshii H. 2018. Release behavior of allyl sulfide from cyclodextrin inclusion complex of allyl sulfide under different storage conditions. Biosci Biotechnol Biochem. 1–8.
  • Ohtsuki M, Morimoto H, Nakagawa H. 2018. Tacrolimus ointment for the treatment of adult and pediatric atopic dermatitis: review on safety and benefits. J Dermatol. 45:936–942.
  • Park S. 2016. Cyclic glucans enhance solubility of bioavailable flavonoids. Molecules. 21:pii: E1556.
  • Pui Y, Chen Y, Chen H, Wang S, Liu C, Tonnis W, Chen L, Serno P, Bracht S, Qian F. 2018. Maintaining supersaturation of nimodipine by PVP with or without the presence of sodium lauryl sulfate and sodium taurocholate. Mol Pharm. 15:2754–2763.
  • Purohit HS, Trasi NS, Sun DD, Chow ECY, Wen H, Zhang X, Gao Y, Taylor LS. 2018. Investigating the impact of drug crystallinity in amorphous tacrolimus capsules on pharmacokinetics and bioequivalence using discriminatory in vitro dissolution testing and physiologically based pharmacokinetic modeling and simulation. J Pharm Sci. 107:1330–1341.
  • Sharma N, Baldi A. 2016. Exploring versatile applications of cyclodextrins: an overview. Drug Deliv. 23:739–757.
  • Shi NQ, Wang SR, Zhang Y, Huo JS, Wang LN, Cai JH, Li ZQ, Xiang B, Qi XR. 2019. Hot melt extrusion technology for improved dissolution, solubility and “spring-parachute” processes of amorphous self-micellizing solid dispersions containing BCS II drugs indomethacin and fenofibrate: profiles and mechanisms. Eur J Pharm Sci. 130:78–90.
  • Tamura S, Ohike A, Ibuki R, Amidon GL, Yamashita S. 2002. Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats. J Pharm Sci. 91:719–729.
  • Tang KT, Tseng CH, Hsieh TY, Chen DY. 2018. Induction therapy for membranous lupus nephritis: a systematic review and network meta-analysis. Int J Rheum Dis. 21:1163–1172.
  • Taupitz T, Dressman JB, Klein S. 2013a. In vitro tools for evaluating novel dosage forms of poorly soluble, weakly basic drugs: case example ketoconazole. J Pharm Sci. 102:3645–3652.
  • Taupitz T, Dressman JB, Klein S. 2013b. New formulation approaches to improve solubility and drug release from fixed dose combinations: case examples pioglitazone/glimepiride and ezetimibe/simvastatin. Eur J Pharm Biopharm. 84:208–218.
  • Thiry J, Kok MG, Collard L, Frere A, Krier F, Fillet M, Evrard B. 2017a. Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule. Eur J Pharm Sci. 99:1–8.
  • Thiry J, Krier F, Ratwatte S, Thomassin JM, Jerome C, Evrard B. 2017b. Hot-melt extrusion as a continuous manufacturing process to form ternary cyclodextrin inclusion complexes. Eur J Pharm Sci. 96:590–597.
  • Wilson V, Lou X, Osterling DJ, Stolarik DF, Jenkins G, Gao W, Zhang GGZ, Taylor LS. 2018. Relationship between amorphous solid dispersion in vivo absorption and in vitro dissolution: phase behavior during dissolution, speciation, and membrane mass transport. J Control Release. 292:172–182.
  • Zhang X, Lin G, Tan L, Li J. 2018. Current progress of tacrolimus dosing in solid organ transplant recipients: pharmacogenetic considerations. Biomed Pharmacother. 102:107–114.
  • Zhu C, Gong S, Ding J, Yu M, Ahmad E, Feng Y, Gan Y. 2019. Supersaturated polymeric micelles for oral silybin delivery: the role of the Soluplus-PVPVA complex. Acta Pharm Sin B. 9:107–117.
  • Zhu Q, Guo T, Xia D, Li X, Zhu C, Li H, Ouyang D, Zhang J, Gan Y. 2013. Pluronic F127-modified liposome-containing tacrolimus-cyclodextrin inclusion complexes: improved solubility, cellular uptake and intestinal penetration. J Pharm Pharmacol. 65:1107–1117.

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