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Original Articles

Antioxidant Properties and Phenolic Composition of Greek Propolis Extracts

, &
Pages 511-522 | Received 24 Aug 2011, Accepted 26 Nov 2011, Published online: 08 Nov 2013

REFERENCES

  • Burdock , G.A. 1998 . Review of the biological properties and toxicity of bee propolis . Food and Chemical Toxicology , 36 : 347 – 363 .
  • Kujumgiev , A. , Tsvetkova , T. , Serkedjieva , Y. , Bankova , V. , Christov , R. and Antibacterial , Popov, S. 1999 . antifungal and antiviral activity of propolis of different geographic origin . Journal of Ethnopharmacology , 64 : 235 – 240 .
  • Banskota , A.H. , Tezuka , Y. and Kadota , S. 2001 . Recent progress in pharmacological research of propolis . Phytotherapy Research , 15 : 561 – 571 .
  • Isla , M.I. , Nieva Moreno , M.I. , Sampietro , A.R. and Vattuone , M.A. 2001 . Antioxidant activity of Argentine propolis extracts . Journal of Ethnopharmacology , 76 : 165 – 170 .
  • Ahn , M.R. , Kunimasa , K. , Ohta , T. , Kumazawa , S. , Kamihira , M. , Kaji , K. , Uto , Y. , Hori , H. , Nagasawa , H. and Nakayama , T. 2007 . Suppression of tumor-induced angiogenesis by Brazilian propolis: Major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation . Cancer Letters , 252 : 235 – 243 .
  • Bankova , V.S. , De Castro , S.L. and Marcucci , M.C. 2000 . Propolis: Recent advances in chemistry and plant origin . Apidologie , 31 : 3 – 15 .
  • Moreno , N.M. , Isla , M.I. , Sampietro , A.R. and Vattuone , M. 2000 . Comparison of the free radical-scavenging activity of propolis from several regions of Argentina . Journal of Ethnopharmacology , 71 : 109 – 114 .
  • Kalogeropoulos , N. , Konteles , S.J. , Troulidou , E. , Mourtzinos , I. and Karathanos , V.T. 2009 . Chemical composition, antioxidant activity and antimicrobial properties of propolis extracts from Greece and Cyprus . Food Chemistry , 116 : 452 – 461 .
  • Luna , L. and Fabani , M. 2009 . Schmeda-Hirschmann, G.; Podio, N.; Wunderlin, D.; Feresin, G. Main flavonoids, DPPH activity and metal content allow determination of the geographical origin of propolis from the province of San Juan (Argentina). Journal of Agricultural and Food Chemistry , 57 : 2691 – 2698 .
  • Isla , M.I. , Paredes-Guzman , J.F. , Nieva-Moreno , M.I. , Koo , H. and Park , Y.K. 2005 . Some chemical composition and biological activity of Northern Argentine propolis . Journal of Agricultural and Food Chemistry , 53 : 1166 – 1172 .
  • Rice-Evans , A.C. , Miller , N.J. and Papanga , G. 1996 . Structure antioxidant activity relationship of flavonoids and phenolic acids . Free Radical Biology and Medicine , 20 : 933 – 956 .
  • Kroon , P.A. and Williamson , G. 1999 . Hydroxycinnamates in plants and food: Current and future perspectives . Journal of the Science of Food and Agriculture , 79 : 355 – 361 .
  • Nijveldt , R.J. , Van Nood , E. , Van Hoorn , D.E.C. , Boelens , P.G. , Van Noren , K. and Van Leeuwen . 2002 . P.A.M. Flavonoids: A review of probable mechanisms of action and potential applications . The American Journal of Clinical Nutrition , 74 : 418 – 425 .
  • Chen , J.H. and Ho , C.T. 1997 . Antioxidant activities of caffeic acid and its related hydroxycinnamic acid compounds . Journal of Agriculture and Food Chemistry , 41 : 2371 – 2378 .
  • Wu , W.-M. , Lu , L. , Long , Y. , Wang , T. , Liu , L. , Chen , Q. and Wang , R. 2007 . Free radical scavenging and antioxidative activities of caffeic acid phenethyl ester (CAPE) and its related compounds in solution and membranes: a structure-activity insight . Food Chemistry , 105 : 107 – 115 .
  • Ogiwara , T. , Satoh , K. , Kadoma , Y. , Murakami , Y. , Unten , S. and AtsumI , T. 2002 . Radical scavenging activity and cytotoxicity of ferulic acid . Anticancer Research , 22 : 2711 – 2717 .
  • Srinivasan , M. , Sudheer , A.R. , Pillai , K.R. , Kumar , P.R. , Sudhakaram , P.R. and Moon , V.P. 2006 . Influence of ferulic acid on gamma-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes . Toxicology , 228 : 249 – 258 .
  • Mandsen , H.L. and Bertelesen , G. 1995 . Spices as antioxidants . Trends of Food Science and Technology , 6 : 271 – 277 .
  • Sancez-Moreno , C. , Jimenez-Escrig , A. and Saura-Calixto , F. 2000 . Study of low density lipoprotein oxidizability indexes to measure the antioxidant activity of dietary polyphenols . Nutrition Research , 20 : 941 – 953 .
  • Cushnie , T.P. and Lamb , A.J. 2005 . Antimicrobial activity of flavonoids . International Journal of Antimicrobial Agents , 26 : 343 – 356 .
  • Haenen , G.R.M.M. and Bast , A. 1999 . Nitric oxide radical scavenging of flavonoids . Methods in Enzymology , 301 : 490 – 503 .
  • Ferry , D.R. , Smith , A. , Malkhandi , J. , Fyfe , D.W. , deTakats , P.G. Anderson , D. 1996 . Phase I clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition . Clinical Cancer Research , 2 : 659 – 668 .
  • Verma , A.K. , Johnson , J.A. , Gould , M.N. and Tanner , M.A. 1988 . Inhibition of 7,12-dimethylbenz(a)anthracene and N-nitrosomethylurea induced mammary cancer by dietary flavonol quercetin . Cancer Research , 48 : 5754 – 5788 .
  • Pignatelli , P. , Pulcinelli , F.M. , Celestini , A. , Lenti , L. , Ghiselli , A. Gazzaniga , P.P. 2000 . The flavonoids quercetin and catechin synergistically inhibit platelet function by antagonizing the intracellular production of hydrogen peroxide . The American Journal of Clinical Nutrition , 72 : 1150 – 1155 .
  • Heo , M.Y. , Lee , J.H. , Sohn , S.J. and Au , W.W. 1996 . Anticlastogenic effects of galangin against mitomycin C-induced micronuclei in reticulocytes of mice . Mutatation Research , 360 : 37 – 41 .
  • Wall , M.E. , Wani , M.C. , Manikumar , G. , Abraham , P. , Taylor , H. , Hughes , T.J. , Warner , J. and McGiveney , R. 1988 . Plant antimutagenic agents . 2. Flavonoids. Journal of Natural Products , 51 : 1084 – 1091 .
  • Cholbi , M.R. , Paya , M. and Alcaraz , M.J. 1991 . Inhibitory effects of phenolic compounds on CCl4-induced microsomal lipid peroxidation . Experientia , 47 : 195 – 199 .
  • Cai , Q. , Rahn , R.Q. and Zhang , R. 1997 . Dietary flavonoids quercetin, luteolin and genistein reduce oxidative DNA damage and lipid peroxidation and quench free radicals . Cancer Letters , 119 : 99 – 107 .
  • Mira , L. , Fernandez , M.T. , Santos , M. , Rocha , R. , Florencio , M.H. and Jennings , K.R. 2002 . Interactions of flavonoids with iron and copper ions a mechanism for their antioxidant activity . Free Radical Research , 36 : 1199 – 1208 .
  • Sadik , C.D. , Sies , H. and Schewe , T. 2003 . Inhibition of 15-lipoxygenases by flavonoids: Structure activity relations and mode of action . Biochemical Pharmacology , 65 : 773 – 781 .
  • McKay , D.L. and Blumberg , J.B. 2006 . A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.) . Phytotherapy Research , 20 : 519 – 530 .
  • Mendes da Silva , J.F. , De Souza , M.C. , Matta , S.R. , De Andrade , M.R. and Vidal , F.V.N . 2006 . Correlation analysis between phenolic levels of Brazilian propolis extracts and their antimicrobial and antioxidant activities . Food Chemistry , 99 : 431 – 435 .
  • Chaillou , L.L. and Nazareno , A. 2009 . Bioactivity of propolis from Santiago del Estero, Argentina related to their chemical composition . LWT–Food Science and Technology , 42 : 1422 – 1427 .
  • Gregoris , E. and Stevanato , R. 2010 . Correlations between polyphenolic composition and antioxidant activity of Venetian propolis . Food and Chemical Toxicology , 48 : 76 – 82 .
  • Scheller , S. , Krol , W. , Swiacik , J. , Owczarek , S. , Gabrys , J. and Shani , J. 1989 . Antitumoral property of ethanolic extract of propolis in mice-bearing Ehrlich carcinoma, as compared to bleomycin . Zeitschrift fur Naturforschung , 44 : 1063 – 1065 .
  • Tosi , E.A. , Ortega , M.E. and Cazzoli , A.F. 2007 . Food preservative based on propolis: Bacteriostatic activity of propolis polyphenols and flavonoids upon Escherichia coli . Food Chemistry , 104 : 1025 – 1029 .
  • Chikaraishi , Y. , Izuta , H. , Mishima , S. and Hara , H. 2010 . Angiostatic effects of Brazilian green propolis and its chemical constituents . Molecular Nutrition and Food Research , 54 : 566 – 575 .
  • Basnet , P. , Matsushige , K. , Hase , K. , Kadota , S. and Nanba , T. 1996 . Four di-O-caffeoyl quinic acid derivatives from propolis . Potent hepatoprotective activity in experimental liver injury models. Biological and Pharmaceutical Bulletin , 19 : 1479 – 1484 .
  • Khayyal , M.T. , El-Ghazaly , M.A. and El-Khatib , A.S. 1993 . Mechanisms involved in the antiinflammatory effect of propolis extract . Drugs under Experimantal and Clinical Research , 19 : 197 – 203 .
  • Nagai , T. , Inoue , R. and Suzuki , N. 2003 . Preparation and antioxidant properties of water extracts of propolis . Food Chemistry , 80 : 29 – 33 .
  • Gulcin , I. , Bursal , E. , Sehitoglu , H.M. , Bilsel , M. and Goren , A.C. 2010 . Polyphenol contents and antioxidant activity of lyophilized aqueous extracts of propolis from Erzurum, Turkey . Food and Chemical Toxicology , 48 : 2227 – 2238 .
  • Laskar , R.A. , R , Nayan and Begum . 2010 . N.A. Antioxidant activity of Indian propolis and its chemical constituents . Food Chemistry , 122 : 233 – 237 .
  • Melliou , E. and Chinou , I. 2004 . Chemical analysis and antimicrobial activity of Greek propolis . Planta Medica , 70 : 515 – 519 .
  • Velikova , M. , Bankova , V. , Sorkun , K. , Houcine , S. , Tsvetkova , I. and Kujumgiev , A. 2000 . Propolis from the Mediterranean region: Chemical composition and antimicrobial activity . Zeitschrift fur Naturforschung , 55 : 790 – 793 .
  • Brand-Williams , W. , Cuvelier , M.E. and Berset , C. 1995 . Use of free radical method to evaluate antioxidant activity . Lebensmittel-Wissenschaft und- Technology , 28 : 25 – 30 .
  • Benzie , I.F. and Strain , J.J. 1996 . The ferric reducing ability of plasma as a measure of “antioxidant power” the FRAP assay . Analytical Biochemistry , 239 : 70 – 76 .
  • Slinkard , K. and Singleton , V.L. 1997 . Total phenol analysis: automation and comparison with manual methods . American Journal of Enology and Viticulture , 28 : 49 – 55 .
  • Zhisen , J. 1999 . The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals . Food Chemistry , 64 : 555 – 559 .
  • Moreira , L. , Dias , L.G. , Pereira , J.A. and Estevinho , L. 2008 . Antioxidant properties, total phenols and pollen analysis of propolis samples from Portugal . Food Chemical and Toxicology , 46 : 3482 – 3485 .
  • Lagouri , V. and Alexandri , G. 2013 . Antioxidant properties of Greek O. Dictamnus and R. officinalis methanol and aqueous extracts-HPLC determination of phenolic acids . International Journal of Food Properties , 16 (3) : 549 – 562 .
  • Silva , F.A. , Borges , F. , Guimaraes , C. , Lima , J.L. , Matos , C. and Reis , S. 2000 . Phenolic acids and derivatives: Studies on the relationship among structure, radical scavenging activity, and physicochemical parameters . Journal of Agricultural and Food Chemistry , 48 : 2122 – 2126 .
  • Graf , E. 1992 . Antioxidant potential of ferulic acid . Free Radical Biology and Medicine , 13 : 435 – 448 .
  • Cholbi , M.R. , Pays , M. and Alcaraz , M.J. 1991 . Inhibitory effects of phenolic compounds on carbon tetrachloride induced microsomal lipid peroxidation . Experientia , 47 : 195 – 199 .
  • Heijnen , C.G. , Haenen , G.R.M.M. , Oostveen , R.M. , Stalpers , E.M. and Bast , A. 2002 . Protection of flavonoids against lipid peroxidation: The structure activity relationship revisited . Free Radical Research , 36 : 575 – 581 .
  • Arts , M.J.T.J. , Dallinga , J.S. , Voss , H.P. and Haenen , G.R.M.M. 2004 . A new approach to assess the total antioxidant capacity using the TEAC assay . Food Chemistry , 88 : 557 – 567 .
  • Russo , A. , Longo , R. and Vanella , A. 2002 . Antioxidant activity of propolis: Role of caffeic acid phenethyl ester and galangin . Fitoterapia , 73 : 21 – 29 .
  • Son , S. and Lewis , B.A. 2002 . Free radical scavenging and antioxidative activity of caffeic acid amide and ester analogues: Structure–activity relationship . Journal of Agriculture and Food Chemistry , 50 : 468 – 472 .
  • Kumazawa , S. , Hamasaka , T. and Nakayama , T. 2004 . Antioxidant activity of propolis of various geographic origins . Food Chemistry , 84 : 329 – 339 .
  • Aliyazicioglu , R. , Sahin , H. , Erturk , O. , Ulusoy , E. and Kolayli , S. 2013 . Properties of phenolic composition and biological activity of propolis from Turkey . International Journal of Food Properties , 16 (2) : 277 – 287 .
  • Mohammadzadeh , S. , Sharriatpanahi , M. , Hamedi , M. , Amanzadeh , Y. , Ebrahimi , S.E.S. and Ostad , S.N. 2007 . Antioxidant power of Iranian propolis extract . Food Chemistry , 103 : 729 – 33 .

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