References
- Klijn CJ, Kappelle LJ. Haemodynamic stroke: clinical features, prognosis, and management. Lancet Neurol. 2010 Oct;9(10):1008–1017. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20864053. doi:10.1016/S1474-4422(10)70185-X
- Jones F, Riazi A. Self-efficacy and self-management after stroke: a systematic review. Disabil Rehabil. 2011 Jan 27;33(10):797–810. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20795919. doi:10.3109/09638288.2010.511415
- Doyle PJ. Measuring health outcomes in stroke survivors. Arch Phys Med Rehabil. 2002 Dec 1;83:S39–S43. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0003999302006238. doi:10.1053/apmr.2002.36838
- Virani SS, Alonso A, Aparicio HJ, et al. Heart disease and stroke statistics—2021 update. Circulation. 2021 Feb 23: E254–E743. Available from: https://www.ahajournals.org/doi/abs/10.1161CIR.0000000000000950.
- Sumer M, Ozdemir I, Erturk O. Progression in acute ischemic stroke: frequency, risk factors and prognosis. J Clin Neurosci. 2003;10(2):177–180. Available from: https://www.sciencedirect.com/science/article/pii/S0967586802003259. doi:10.1016/S0967-5868(02)00325-9
- Lim SH, Lee JS, Lee JI, et al. The quantitative assessment of functional impairment and its correlation to infarct volume in rats with transient middle cerebral artery occlusion. Brain Res. 2008;1230:303–309. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18675259. doi:10.1016/j.brainres.2008.07.002
- Menzies SA, Hoff JT, Betz AL. Middle cerebral artery occlusion in rats. Neurosurgery [Internet]. 1992 Jul 1;31(1):100–107. Available from: https://academic.oup.com/neurosurgery/article/31/1/100/2751985.
- Sagai M, Bocci V. Mechanisms of action involved in ozone therapy: Is healing induced via a mild oxidative stress? Med Gas Res. 2011 Dec 20;1(1):29. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22185664. doi:10.1186/2045-9912-1-29
- Travagli V, Zanardi I, Silvietti A, et al. A physicochemical investigation on the effects of ozone on blood. Int J Biol Macromol. 2007 Dec 1;41(5):504–511. Available from: https://www.sciencedirect.com/science/article/pii/S0141813007001675. doi:10.1016/j.ijbiomac.2007.06.010
- Bocci V, Borrelli E, Travagli V, et al. The ozone paradox: ozone is a strong oxidant as well as a medical drug. Med Res Rev. 2009 Jul;29(4):646–682. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19260079. doi:10.1002/med.20150
- Johnson JA, Johnson DA, Kraft AD, et al. The Nrf2-ARE pathway. Ann N Y Acad Sci. 2008 Dec;1147(1):61–69. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19076431. doi:10.1196/annals.1427.036
- Bocci V, Zanardi I, Travagli V. Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects. Med Gas Res. 2011;1:1–6. Available from: /pmc/articles/PMC3231820/?report = abstract. doi:10.1186/2045-9912-1-1
- Tufekci KU, Civi Bayin E, Genc S, et al. The Nrf2/ARE pathway: a promising target to counteract mitochondrial dysfunction in Parkinson’s disease. Parkinson’s Disease [Internet]. 2011 Feb 22: 1–14. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21403858.
- Frosini M, Contartese A, Zanardi I, et al. Selective ozone concentrations may reduce the ischemic damage after a stroke. Free Radic Res. 2012 May 14;46(5):612–618. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22263539. doi:10.3109/10715762.2012.659247
- Fuccio C, Luongo C, Capodanno P, et al. A single subcutaneous injection of ozone prevents allodynia and decreases the over-expression of pro-inflammatory caspases in the orbito-frontal cortex of neuropathic mice. Eur J Pharmacol. 2009 Jan 28;603(1–3):42–49. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19100257. doi:10.1016/j.ejphar.2008.11.060
- Ozbay I, Ital I, Kucur C, et al. Effects of ozone therapy on facial nerve regeneration. Braz J Otorhinolaryngol. 2017;83(2):168–175. Available from: www.bjorl.org. doi:10.1016/j.bjorl.2016.02.009
- Ozturk O, Tezcan AH, Adali Y, et al. Effect of ozone and methylprednisolone treatment following crush type sciatic nerve injury. Acta Cirurgica Brasileira. 2016 Nov;31(11):730–735. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502016001100730&lng=en&tlng=en. doi:10.1590/s0102-865020160110000005
- Somay H, Emon ST, Uslu S, et al. The histological effects of ozone therapy on sciatic nerve crush injury in rats. World Neurosurg. 2017 Sep 1;105:702–708. Available from: https://www.sciencedirect.com/science/article/pii/S187887501730863X. doi:10.1016/j.wneu.2017.05.161
- Yucesoy T, Kutuk N, Canpolat DG, et al. Comparison of ozone and photo-biomodulation therapies on mental nerve injury in rats. J Oral Maxillofac Surg. 2017 Nov;75(11):2323–2332. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28529151. doi:10.1016/j.joms.2017.04.016
- Tricarico G, Isakovic J, Song M, et al. Ozone influences migration and proliferation of neural stem cells in vitro. Neurosci Lett [Internet]. 2020 Nov 20: 739. Available from: https://pubmed.ncbi.nlm.nih.gov/32947004/.
- Cai H, Tao X, Zheng L, et al. Ozone alleviates ischemia/reperfusion injury by inhibiting mitochondrion-mediated apoptosis pathway in SH-SY5Y cells. Cell Biol Int. 2020 Apr 21;44(4):975–984. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002cbin.11294. doi:10.1002/cbin.11294
- Clavo B, Catalá L, Pérez JL, et al. Ozone therapy on cerebral blood flow: a preliminary report. Evidence-Based Complementary Altern Med. 2004 Dec;1(3):315–319. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15841265. doi:10.1093/ecam/neh039
- Orlandin JR, Gomes IdS, Leandro SdF, et al. Treatment of chronic spinal cord injury in dogs using amniotic membrane-derived stem cells: preliminary results. Stem Cells Cloning: Adv Appl. 2021 Oct 18;14:39–49. Available from: https://www.dovepress.com/treatment-of-chronic-spinal-cord-injury-in-dogs-using-amniotic-membran-peer-reviewed-fulltext-article-SCCAA.
- Cardoso M, Pinheiro A, Vidane A, et al. Characterization of teratogenic potential and gene expression in canine and feline amniotic membrane-derived stem cells. Reprod Domest Anim. 2017 Apr;52:58–64. Available from: http://doi.wiley.com/10.1111rda.12832. doi:10.1111/rda.12832
- Vidane A, Pinheiro A, Casals J, et al. Transplantation of amniotic membrane-derived multipotent cells ameliorates and delays the progression of chronic kidney disease in cats. Reprod Domest Anim. 2017 Apr;52:316–326. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27774657. doi:10.1111/rda.12846
- Ambrosio C, Vidane A, Souza A, et al. Cat amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation. Stem Cells Cloning: Adv Appl. 2014 Aug;7:71. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25249758.
- Pinheiro A de O, Lara VM, Souza AF, et al. Characterization and immunomodulation of canine amniotic membrane stem cells. Stem Cells Cloning: Adv Appl. 2020 May 7;13:43–55. Available from: https://www.dovepress.com/characterization-and-immunomodulation-of-canine-amniotic-membrane-stem-peer-reviewed-fulltext-article-SCCAA.
- King N, Korolchuk S, McGivan JD, et al. A new method of quantifying glutathione levels in freshly isolated single superfused rat cardiomyocytes. J Pharmacol Toxicol Methods. 2004 Nov;50(3):215–222. Available from: https://pubmed.ncbi.nlm.nih.gov/15519908/. doi:10.1016/j.vascn.2004.05.003
- Casaril AM, Segatto N, Simões L, et al. Neuroprotective effect of 3-[(4-Chlorophenyl)selanyl]−1-methyl-1H-indole on hydrogen peroxide-induced oxidative stress in SH-SY5Y cells. Neurochem Res. 2021 Mar 1;46(3):535–549. Available from: https://link.springer.com/article/10.1007s11064-020-03190-0.
- Moldogazieva NT, Mokhosoev IM, Mel’Nikova TI, et al. Oxidative stress and advanced lipoxidation and glycation end products (ALEs and AGEs) in aging and age-related diseases. Oxid Med Cell Longev. 2019. Available from: /pmc/articles/PMC6710759/
- Berry R, López-Martínez G. A dose of experimental hormesis: when mild stress protects and improves animal performance. Comp Biochem Physiol A Mol Integr Physiol. 2020 Apr 1;242:110658. doi:10.1016/j.cbpa.2020.110658
- Bocci VA, Zanardi I, Travagli V. Ozone acting on human blood yields a hormetic dose-response relationship. J Transl Med. 2011 May 17;9(1):66. Available from: https://translational-medicine.biomedcentral.com/articles/10.11861479-5876-9-66. doi:10.1186/1479-5876-9-66
- Bocci V. The potential toxicity of ozone: side effects and contraindications of ozonetherapy. In: OZONE [Internet]. Dordrecht: Springer Netherlands; 2010. p. 75–84. Available from: http://link.springer.com/10.1007978-90-481-9234-2_7
- Bocci V. How does ozone act? How and why can we avoid ozone toxicity? In: OZONE [Internet]. Dordrecht: Springer Netherlands; 2010. p. 17–26. Available from: http://link.springer.com/10.1007978-90-481-9234-2_4
- Bocci V. Physical-chemical properties of ozone – Natural production of ozone: the toxicology of ozone. In: OZONE [Internet]. Dordrecht: Springer Netherlands; 2010. p. 1–4. Available from: http://link.springer.com/10.1007978-90-481-9234-2_1
- Bocci V. Is it true that ozone is always toxic? The end of a dogma. Toxicol Appl Pharmacol. 2006 Nov 1;216(3):493–504. Available from: https://pubmed.ncbi.nlm.nih.gov/16890971/. doi:10.1016/j.taap.2006.06.009
- Frosini M, Contartese A, Zanardi I, et al. Selective ozone concentrations may reduce the ischemic damage after a stroke. Free Radic Res. 2012 May 14;46(5):612–618. Available from: http://www.tandfonline.com/doi/full/10.310910715762.2012.659247 doi:10.3109/10715762.2012.659247
- Onal O, Yetisir F, Sarer AES, et al. Prophylactic ozone administration reduces intestinal mucosa injury induced by intestinal ischemia-reperfusion in the Rat. Mediators Inflamm. 2015. Available from: /pmc/articles/PMC4487723/
- Rodriǵuez ZZ, Guanche D, Álvarez RG, et al. Preconditioning with ozone/oxygen mixture induces reversion of some indicators of oxidative stress and prevents organic damage in rats with fecal peritonitis. Inflammation Res. 2009;58(7):371–375. Available from: https://pubmed.ncbi.nlm.nih.gov/19274439/. doi:10.1007/s00011-009-0001-2
- Laszczyca P, Kawka-Serwecińska E, Witas I, et al. Lipid peroxidation and activity of antioxidative enzymes in the rat model of ozone therapy. Materia Medica Polona. 1996;28(4):155–160. Available from: https://pubmed.ncbi.nlm.nih.gov/9308339/.
- Clavo B, Rodríguez-Esparragón F, Rodríguez-Abreu D, et al. Modulation of oxidative stress by ozone therapy in the prevention and treatment of chemotherapy-induced toxicity: review and prospects. Antioxidants. 2019 Nov 26;8(12):588. Available from: https://www.mdpi.com/2076-3921/8/12/588. doi:10.3390/antiox8120588
- Larini A, Bocci V. Effects of ozone on isolated peripheral blood mononuclear cells. Toxicol in Vitro. 2005 Feb;19(1):55–61. doi:10.1016/j.tiv.2004.06.007
- Peralta C, Xaus C, Bartrons R, et al. Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion. Free Radic Res. 2000;33(5):595–605. Available from: https://pubmed.ncbi.nlm.nih.gov/11200091/. doi:10.1080/10715760000301121
- Bocci V, Valacchi G, Corradeschi F, et al. Studies on the biological effects of ozone: 7. generation of reactive oxygen species (ROS) after exposure of human blood to ozone. J Biol Regul Homeost Agents. 1998;12(3):67–75. Available from: https://pubmed.ncbi.nlm.nih.gov/9795834/.
- Re L. Ozone in medicine: a few points of reflections. Front Physiol. 2022 Feb 23;13:103.
- Tricarico G, Travagli V. The relationship between ozone and human blood in the course of a well-controlled, mild, and transitory oxidative eustress. Antioxidants. 2021 Dec 1;10(12):1946–1960. Available from: https://pubmed.ncbi.nlm.nih.gov/34943049/. doi:10.3390/antiox10121946
- Koca K, Yurttaş Y, Yildiz C, et al. Effect of hyperbaric oxygen and ozone preconditioning on oxidative/nitrosative stress induced by tourniquet ischemia/reperfusion in rat skeletal muscle. Acta Orthop Traumatol Turc. 2010;44(6):476–483. Available from: https://pubmed.ncbi.nlm.nih.gov/21358255/. doi:10.3944/AOTT.2010.2327
- Ekici S, Doan Ekici AI, Öztürk G, et al. Comparison of melatonin and ozone in the prevention of reperfusion injury following unilateral testicular torsion in rats. Urology. 2012 Oct;80(4):899–906. Available from: https://pubmed.ncbi.nlm.nih.gov/22950989/. doi:10.1016/j.urology.2012.06.049
- Merin O, Attias E, Elstein D, et al. Ozone administration reduces reperfusion injury in an isolated rat heart model. J Card Surg. 2007 Jul;22(4):339–342. Available from: https://pubmed.ncbi.nlm.nih.gov/17661780/. doi:10.1111/j.1540-8191.2007.00419.x
- Kurtoglu T, Durmaz S, Akgullu C, et al. Ozone preconditioning attenuates contrast-induced nephropathy in rats. J Surg Res. 2015 May 15;195(2):604–611. Available from: https://www.sciencedirect.com/science/article/pii/S0022480415000700. doi:10.1016/j.jss.2015.01.041
- Wang L, Chen H, Liu XH, et al. The protective effect of ozone oxidative preconditioning against hypoxia/reoxygenation injury in rat kidney cells. Ren fail. 2014 Sep 23;36(9):1449–1454. Available from: https://www.tandfonline.com/doi/abs/10.3109/0886022X.2014.950934.
- Meng W, Xu Y, Li D, et al. Ozone protects rat heart against ischemia-reperfusion injury: A role for oxidative preconditioning in attenuating mitochondrial injury. Biomed Pharmacother. 2017 Apr 1;88:1090–1097. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0753332216320030. doi:10.1016/j.biopha.2017.01.151
- Orlandin JR, Machado LC, Ambrósio CE, et al. Ozone and its derivatives in veterinary medicine: A careful appraisal. Vet Anim Sci. 2021 Sep 1;13:100191. doi:10.1016/j.vas.2021.100191